Lymphangiosarcoma of the scalp.

Abstract:

BACKGROUND:Lymphangiosarcoma is a rare, aggressive malignancy that originates from the endothelial cells lining lymphatic vessels and carries an extremely poor prognosis. Its clinical and histologic features are often indistinguishable from angiosarcoma. OBJECTIVE:We sought to better characterize the clinical and histologic features of lymphangiosarcoma. METHODS:Case report and review of the literature. RESULTS:A number of immunohistochemical markers, including Von Willebrand factor, Ulex europaeus agglutinin 1, CD31, VEGFR-3, D2-40, Prox-1, can be used to help differentiate lymphatic from vascular tissue. CONCLUSIONS:Recent characterization of several new biologic markers has allowed greater differentiation between these tumors and may provide new therapeutic targets for treatment.

journal_name

J Cutan Med Surg

authors

Mamelak AJ,Collie MR,Kroll R,Hanson ML,Harris HM

doi

10.2310/7750.2013.13025

subject

Has Abstract

pub_date

2014-03-01 00:00:00

pages

132-6

issue

2

eissn

1203-4754

issn

1615-7109

journal_volume

18

pub_type

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