Epidermolysis bullosa acquisita responsive to dapsone therapy.

abstract：BACKGROUND:Pseudoxanthoma elasticum-like papillary dermal elastolysis (PXE-PDE), a rare acquired elastolytic disorder, occurs in postmenopausal, elderly women and is characterized by soft, white-yellow papules that localize on the neck and supraclavicular regions and often coalesce into cobblestone plaques. It has no s...

journal_title：Journal of cutaneous medicine and surgery

authors： Valbuena V,Assaad D,Yeung J

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Forty-nine years ago the first complete and authoritative English text on the physiology and biochemistry of the skin was published by Stephen Rothman, an early basic researcher in dermatology. OBJECTIVE:The purpose of the article is to learn more about Stephen Rothman and his 1954 text, to learn more about...

journal_title：Journal of cutaneous medicine and surgery

authors： Jackson R

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Selective cyclooxygenase (COX) 2 nonsteroidal anti-inflammatory drugs (NSAIDs) have been associated with a general lower incidence of side effects compared with nonselective NSAIDs. Postmarketing information has highlighted the need to reassess the risk evaluation for specific organs, including the skin. OB...

journal_title：Journal of cutaneous medicine and surgery

authors： Atzori L,Pinna AL,Pau M,Aste N,Zucca M,Ferreli C

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:We report on a 42-year-old man with Stage IIA non-Hodgkin's lymphoma who developed a severe mucocutaneous blistering eruption. His diagnosis, paraneoplastic pemphigus, was based on clinical, histological, and immunofluorescence findings and confirmed by immunoprecipitation. Despite maximal ther...

journal_title：Journal of cutaneous medicine and surgery

authors： Ng PP,Rencic A,Nousari HC

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:Neurofibromatosis type 1 (NF1) is a neurocutaneous disorder caused by loss-of-function mutation in the NF1 gene. Segmental or mosaic NF1 (MNF) is an uncommon presentation of the NF1 result of postzygotic mutations that present with subtle localised clinical findings. OBJECTIVES:Our study's objectives were t...

journal_title：Journal of cutaneous medicine and surgery

authors： Lara-Corrales I,Moazzami M,García-Romero MT,Pope E,Parkin P,Shugar A,Kannu P

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Perforating dermatoses are a rare group of dermatologic conditions characterized by transepidermal elimination of dermal material that can be primary or acquired secondary to systemic disease. OBJECTIVE:We present an atypical case of perforating dermatosis resembling elastosis perforans serpiginosa (EPS) pr...

journal_title：Journal of cutaneous medicine and surgery

authors： Cloutier-Bosworth A,Naert K,Kirshen C

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Giant basal cell carcinomas (GBCC) can demonstrate very malignant behavior and pose a surgical challenge. OBJECTIVE:To present a surgical technique utilizing Mohs and the resection of narrow bands of tissue to excise a GBCC that created a large facial defect of 5 cm × 2 cm. METHODS:A unique combination of ...

journal_title：Journal of cutaneous medicine and surgery

authors： Nolan K,Henry M,Shohet M,Elahi E,Marmur E

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:To date, there is no standard treatment of folliculitis decalvans (FD), a rare type of cicatricial alopecia. OBJECTIVE AND METHODS:The records of 23 patients with FD (1998-2012) were retrospectively analyzed, with added data review on the course and treatment of long-standing cases. RESULTS:Initial managem...

journal_title：Journal of cutaneous medicine and surgery

authors： Bunagan MJ,Banka N,Shapiro J

更新日期：2014-10-01 00:00:00

abstract：:A renaissance is taking place in the field of wound healing. Interest in wounds has probably never been so great, and a number of key therapeutic advances in the last 2 or 3 years are only an indication of more progress to come. In large part, we are benefitting from decades of basic research that has provided the kno...

journal_title：Journal of cutaneous medicine and surgery

authors： Falanga V

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:Patient nonattendance is a frequent occurrence in dermatology clinics, and our responsibility regarding the follow-up of these patients remains nebulous. OBJECTIVE:This study sought to evaluate the beliefs and practices of physicians at a university-affiliated medical dermatology clinic regarding patient no...

journal_title：Journal of cutaneous medicine and surgery

authors： Nasseri E,Bertrand J,Brassard D,Fortier-Riberdy G,Marcil I

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Schnitzler syndrome (SS) is a rare autoinflammatory disorder characterized by a recurrent urticarial rash and a monoclonal immunoglobulin M gammopathy, as well as 2 of the following minor criteria: recurrent fever (>38°C), objective signs of abnormal bone remodeling, elevated C-reactive protein level or leuk...

journal_title：Journal of cutaneous medicine and surgery

authors： Urbanski M,Holfeld K,Milne A,Abbas M

更新日期：2016-11-01 00:00:00

abstract：:Acne vulgaris, a condition that can affect people at any age, is the most common cause of referral to a dermatologist. Isotretinoin (ITT) is the most effective treatment available, but serious adverse effects, including a possible association with depression and suicide, limit its use. We review the current literature...

journal_title：Journal of cutaneous medicine and surgery

authors： Oliveira JM,Sobreira G,Velosa J,Telles Correia D,Filipe P

更新日期：2018-01-01 00:00:00

abstract：:Juvenile xanthogranuloma (JXG) is a member of the non-Langerhans cell group of proliferative disorders of mononuclear phagocytes. JXG is a benign tumour of histiocytic cells. Classic JXG is divided into 2 main clinical subtypes: dome-shaped papules (<0.5 cm) and single/multiple nodules (<2.0 cm). A rare variant is ref...

journal_title：Journal of cutaneous medicine and surgery

authors： Ladha MA,Haber RM

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Lichen planopilaris (LPP) is believed to be a follicular variant of lichen planus that affects pilosebaceous units, mainly of the scalp. An extremely rare variant of LPP is a linear form, which follows the lines of Blaschko. Of the five previously documented cases of linear LPP, all were limited to the face....

journal_title：Journal of cutaneous medicine and surgery

authors： Baker K,Pehr K

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:Multiple symmetric lipomatosis (MSL) is a relatively uncommon entity of unknown etiology characterized by symmetrically subcutaneous accumulation of nonencapsulated adipose tissue. Approximately 200 to 300 cases have been published. OBJECTIVES:The aims of this article are to report the case of a 58-year-old...

journal_title：Journal of cutaneous medicine and surgery

authors： Gomes da Silva R,Detoffol Bragança R,Ribeiro Costa C,Torres de Melo L,Weiss Telles R,Costa Silva L

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Omalizumab is a third-line treatment for chronic spontaneous urticaria (CSU). Studies investigating the use of higher doses of omalizumab in patients unresponsive to regular doses are limited. OBJECTIVES:This study aims to investigate the effectiveness and safety of omalizumab 450 mg in CSU. METHODS:A retr...

journal_title：Journal of cutaneous medicine and surgery

authors： Salman A,Comert E

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:The number of dermatology residency positions in Canada has not reflected the growing workforce shortage. Until 2005, all dermatology residents at the University of Ottawa were committed to return to their funding area at the completion of their training. This has left Eastern Ontario with a critical shortag...

journal_title：Journal of cutaneous medicine and surgery

authors： Heughan C,Kanigsberg N,Amdemichael E,Fergusson D,Ammerman D

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Nail changes are common in psoriatic arthritis (PsA), with varying relationships existing between skin, nail, and joint disease. OBJECTIVE:To further characterize relationships between nail changes, psoriasis, and joint involvement in PsA patients. METHODS:One hundred eighty-eight PsA patients had skin, fi...

journal_title：Journal of cutaneous medicine and surgery

authors： Sandre MK,Rohekar S,Guenther L

更新日期：2015-07-01 00:00:00

abstract：:As clinical dermatologists, we are all striving to achieve the highest possible accuracy in our clinical acumen and diagnostic skills. Over the past decade, one relatively simple advance, epiluminescence microscopy with the use of the dermatoscope, has significantly contributed to our diagnostic skills in the detectio...

journal_title：Journal of cutaneous medicine and surgery

authors： Sauder DN

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND:It has been demonstrated that hypertrophic scar fibroblasts (HSFs) overexpress collagen messenger ribonucleic acid (mRNA) and protein, especially alpha1 collagen. Antisense nucleic acids are effective in inhibiting harmful or uncontrolled gene expression, suggesting that antisense ribonucleic acid (RNA) can ...

journal_title：Journal of cutaneous medicine and surgery

authors： Ju-Lin X,Shao-Hai Q,Tian-Zeng L,Chao-Quan L,Hou-Dong L,Ying-Bin X,Xu-Sheng L,Bin S,Hui-Zhen L,Yong H

更新日期：2009-05-01 00:00:00

abstract：:Atopic dermatitis (AD) is the most common pediatric chronic inflammatory skin disease in North America, often involving complex treatment regimens and impairing the quality of life of affected children and their families. Two topical calcineurin inhibitors (TCIs) have been available for the treatment of AD in pediatri...

journal_title：Journal of cutaneous medicine and surgery

authors： Fiorillo L,Marcoux D,Ramien M

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Sjögren syndrome (SS) is a chronic autoimmune inflammatory disease that involves primarily the exocrine glands, resulting in their functional impairment. SS typically presents as dry eyes (xerophthalmia) and dry mouth (xerostomia). This process can manifest either as the independent phenomenon of primary SS ...

journal_title：Journal of cutaneous medicine and surgery

authors： Kittridge A,Routhouska SB,Korman NJ

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Alefacept (Amevive) is a fully human LFA-3/IgG1 fusion protein with a dual mechanism of action inhibiting T-cell activation and selectively reducing memory T cells. Alefacept is currently approved as a 12-week course of weekly 15 mg intramuscular (IM) injections for the treatment of adults with moderate to s...

journal_title：Journal of cutaneous medicine and surgery

authors： Moul DK,Routhouska SB,Korman NJ

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:Tumour size is a crucial factor used to plan Mohs procedures. Larger tumours require more time and stages of excision, and they need to be triaged as a higher priority. Therefore, the accuracy in measurement of tumour size is critical. OBJECTIVE:To investigate if there is a significant difference in accurac...

journal_title：Journal of cutaneous medicine and surgery

authors： To D,Macdonald J

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Emotional stress has been associated with the development of alopecia areata (AA) and androgenetic alopecia (AGA). Emotional intelligence (EI), a component of general intelligence, is thought to govern the recognition, expression, and control of stress and other emotions. People with low EI are unable to ade...

journal_title：Journal of cutaneous medicine and surgery

authors： Monselise A,Bar-On R,Chan L,Leibushor N,McElwee K,Shapiro J

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:In 1997, it was reported that a PTEN gene deletion, a common genetic mutation in Cowden's disease (CD), was identified in a patient with Bannayan-Riley-Ruvacalba (BRR), suggesting that the two diseases were allelic. However, the clinical overlap between the two diseases has largely remained unclear. OBJECTI...

journal_title：Journal of cutaneous medicine and surgery

authors： Blum RR,Rahimizadeh A,Kardon N,Lebwohl M,Wei H

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Systemic therapy for atopic dermatitis (AD) has been challenging with limited safe and efficacious long-term treatment options. In 2017, dupilumab was approved in the United States, Europe, and Canada as the first targeted therapy for patients with moderate-to-severe AD. Despite promising efficacy and safety...

journal_title：Journal of cutaneous medicine and surgery

authors： Jo CE,Georgakopoulos JR,Ladda M,Ighani A,Mufti A,Drucker AM,Piguet V,Yeung J

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Dermatofibrosarcoma protuberans with fibrosarcomatous differentiation (DFSP-FS) is a rare variant of DFSP with a more aggressive clinical course, characterized by higher rates of local recurrence, metastasis, and death. METHODS:We conducted a clinicopathologic review of all DFSP-FS cases that occurred in Al...

journal_title：Journal of cutaneous medicine and surgery

authors： Kuzel P,Mahmood MN,Metelitsa AI,Salopek TG

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Merkel cell carcinoma is a rare, aggressive, malignant cutaneous tumor of the elderly or immunosuppressed individuals that usually appears on sun-exposed areas of the body. Its pathogenesis is still debated, and, currently, no standardized treatment exists. OBJECTIVE:To provide a current updated review of t...

journal_title：Journal of cutaneous medicine and surgery

authors： Zampetti A,Feliciani C,Massi G,Tulli A

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Vitiligo can negatively affect patients' quality of life (QoL). Assessment of QoL provides relevant information about treatment benefits. OBJECTIVES:To examine the effects of excimer laser treatment on vitiligo patients' QoL and to identify overall patient satisfaction. The literature review failed to show ...

journal_title：Journal of cutaneous medicine and surgery

authors： Al-Shobaili HA

更新日期：2014-10-01 00:00:00