Antiangiogenic properties of a novel shark cartilage extract: potential role in the treatment of psoriasis.

abstract：BACKGROUND:Fewer dermatologists than other clinical specialists are entering and being retained as physicians in the Canadian medical workforce. Studies suggest that dermatologist numbers may influence skin disease outcomes. No study has questioned whether the number of clinical dermatologists can influence academic pr...

journal_title：Journal of cutaneous medicine and surgery

authors： Canzi Lanzini R,Fallen RS,Wismer J,Lima HC

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Vitiligo can negatively affect patients' quality of life (QoL). Assessment of QoL provides relevant information about treatment benefits. OBJECTIVES:To examine the effects of excimer laser treatment on vitiligo patients' QoL and to identify overall patient satisfaction. The literature review failed to show ...

journal_title：Journal of cutaneous medicine and surgery

authors： Al-Shobaili HA

更新日期：2014-10-01 00:00:00

abstract：:Oral glucocorticoids are commonly used across every field of medicine; however, discontinuing them in patients can be challenging. The risk of acute adrenal crises secondary to glucocorticoid withdrawal can be fatal and arises from chronic suppression of the adrenal glands. Identifying risk factors for adrenal suppres...

journal_title：Journal of cutaneous medicine and surgery

authors： Nicholas MN,Li SK,Dytoc M

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Neurofibromatosis type 1 (NF1) is a neurocutaneous disorder caused by loss-of-function mutation in the NF1 gene. Segmental or mosaic NF1 (MNF) is an uncommon presentation of the NF1 result of postzygotic mutations that present with subtle localised clinical findings. OBJECTIVES:Our study's objectives were t...

journal_title：Journal of cutaneous medicine and surgery

authors： Lara-Corrales I,Moazzami M,García-Romero MT,Pope E,Parkin P,Shugar A,Kannu P

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:A new treatment for actinic keratoses, ingenol mebutate, was recently approved by the US Food and Drug Administration. OBJECTIVE:To review the mechanisms of action, efficacy and safety data, and practical recommendations for ingenol mebutate. METHODS:The PubMed and clinicaltrials.gov databases were searche...

journal_title：Journal of cutaneous medicine and surgery

authors： Gupta AK,Paquet M

更新日期：2013-05-01 00:00:00

abstract：:Genital ulcer disease can be caused by a wide variety of sources. Most commonly, genital ulcer disease is grouped into infectious and noninfectious causes. HSV, syphilis, lymphogranuloma venereum, and chancroid represent some common infectious ulcers. Noninfectious causes on the other hand can be inflammatory, noninfl...

journal_title：Journal of cutaneous medicine and surgery

authors： Maliyar K,Mufti A,Syed M,Selk A,Dutil M,Bunce PE,Alavi A

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:We report a case of primary systemic amyloidosis in a 78-year-old Caucasian woman presented as a nonhealing ulcer on the right thigh for 3 months. Histopathology of the skin revealed widely thickened walls of middermal and subcutaneous vessels from deposition of amorphous eosinophilic material that stained p...

journal_title：Journal of cutaneous medicine and surgery

authors： Alhaddab M,Srolovitz H,Rosen N

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Selective cyclooxygenase (COX) 2 nonsteroidal anti-inflammatory drugs (NSAIDs) have been associated with a general lower incidence of side effects compared with nonselective NSAIDs. Postmarketing information has highlighted the need to reassess the risk evaluation for specific organs, including the skin. OB...

journal_title：Journal of cutaneous medicine and surgery

authors： Atzori L,Pinna AL,Pau M,Aste N,Zucca M,Ferreli C

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Mycobacterium marinum infections have been reported for over 50 years, mostly in association with trauma in the setting of water exposure. OBJECTIVE:The differential diagnosis for nodules in a sporotrichoid distribution with simultaneous bursitis is discussed. Mycobacterium marinum treatment regimens for sk...

journal_title：Journal of cutaneous medicine and surgery

authors： Saadatmand B,Poulton JK,Kauffman CL

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:Dermatofibrosarcoma protuberans with fibrosarcomatous differentiation (DFSP-FS) is a rare variant of DFSP with a more aggressive clinical course, characterized by higher rates of local recurrence, metastasis, and death. METHODS:We conducted a clinicopathologic review of all DFSP-FS cases that occurred in Al...

journal_title：Journal of cutaneous medicine and surgery

authors： Kuzel P,Mahmood MN,Metelitsa AI,Salopek TG

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:PASI is an inadequate outcome measure for the assessment of psoriasis treatments. No currently used endpoints provide a benefit: risk assessment of treatment taking into consideration all available efficacy and safety data. OBJECTIVE:To propose a new outcome measure called "safe psoriasis control" (SPC), wh...

journal_title：Journal of cutaneous medicine and surgery

authors： Papp KA,Henninger E

更新日期：2005-12-01 00:00:00

abstract：:The association between isotretinoin and atypical wound healing remains controversial. It is common practice to delay elective procedures for 6 to 24 months after oral isotretinoin therapy. The studies supporting common practices (SCP) recommend extending this period to include the 6 to 24 months preceding treatment. ...

journal_title：Journal of cutaneous medicine and surgery

authors： McDonald KA,Shelley AJ,Alavi A

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Merkel cell carcinoma is a rare, aggressive, malignant cutaneous tumor of the elderly or immunosuppressed individuals that usually appears on sun-exposed areas of the body. Its pathogenesis is still debated, and, currently, no standardized treatment exists. OBJECTIVE:To provide a current updated review of t...

journal_title：Journal of cutaneous medicine and surgery

authors： Zampetti A,Feliciani C,Massi G,Tulli A

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:The use of photodynamic therapy (PDT) with topical aminolevulinic acid (ALA) on large skin surfaces has recently been reported for patients with multiple actinic keratoses. OBJECTIVE:The current study compared the ability of topical and systemic ALA-PDT as well as topical ALA-PDT with blue light to delay th...

journal_title：Journal of cutaneous medicine and surgery

authors： Liu Y,Viau G,Bissonnette R

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Indoor tanning (IT) in fitness facilities encourages a misleading positive relationship between tanning and health. While IT in Canadian fitness facilities has been studied, American literature regarding this topic is lacking. OBJECTIVES:The objective of this study is to evaluate availability, cost, reporte...

journal_title：Journal of cutaneous medicine and surgery

authors： Huang CM,Kirchhof MG

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Moderate to severe chronic hand dermatitis (CHD) is not well controlled by current medical strategies; however, recent studies have shown significant improvement in patients treated with up to 6 months of oral alitretinoin (9-cis-retinoic acid). The results of longer-term continuous treatment are lacking. O...

journal_title：Journal of cutaneous medicine and surgery

authors： Gulliver WP,Baker KA

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Cytomegalovirus (CMV) infection usually remains asymptomatic in immunocompetent adults, and few cases of complicated disease in nonimmunosuppressed patients have been reported. Erythema multiforme (EM), an acute and self-limiting skin eruption characterized by a typical targetoid lesion that may also affect ...

journal_title：Journal of cutaneous medicine and surgery

authors： Vitiello M,Echeverria B,Elgart G,Kerdel F

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:The classification of many pigmented lesions is not well defined, and an association with melanoma has not been established. OBJECTIVE:To better define the spectrum of pigmented lesions (excluding common and dysplastic nevi) and explore links to melanoma. METHODS:Retrospective review of patients with total...

journal_title：Journal of cutaneous medicine and surgery

authors： Menon K,Dusza SW,Marghoob AA,Halpern AC,Nehal KS

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:An eczema action plan (EAP) is an individualized tool to help caregivers and patients self-manage eczema. While novel illustrated EAPs have been developed and validated, there is limited literature examining the value of EAPs from patient and caregiver perspectives. OBJECTIVES:The objective of this study wa...

journal_title：Journal of cutaneous medicine and surgery

authors： Shelley AJ,McDonald KA,McEvoy A,Sauder M,Kanigsberg N,Zemek R,Vaillancourt R,Pouliot A,Ramien ML

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Plantar warts are typically resistant to treatment. In recent years, treatments have included administration of intralesional tuberculin; measles, mumps, rubella vaccine; and Candida albicans antigen immunotherapy. To the best of our knowledge, there are no reports of intralesional vitamin D administration f...

journal_title：Journal of cutaneous medicine and surgery

authors： Aktaş H,Ergin C,Demir B,Ekiz Ö

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Elephantiasis is a well-known condition in dermatology usually affecting the legs and external genitalia. It is characterized by chronic inflammation and obstruction of the lymphatic channels and by hypertrophy of the skin and subcutaneous tissues. The etiology is either idiopathic or caused by a variety of ...

journal_title：Journal of cutaneous medicine and surgery

authors： Hanna D,Cloutier R,Lapointe R,Desgagné A

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Crohn disease of the vulva is a rare disease that is difficult to diagnose. There are limited reports describing treatment of this condition. OBJECTIVE:To describe the diagnosis and treatment of a 16-year-old girl with Crohn disease of the vulva, without onset of intestinal symptoms. METHODS:Crohn disease ...

journal_title：Journal of cutaneous medicine and surgery

authors： Zhang AJ,Zhan SH,Chang H,Gao YQ,Li YQ

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Ear keloids continue to be a therapeutic challenge. OBJECTIVE:To evaluate the clinical success of a modified "oyster splint technique." METHODS:Ten patients with an ear keloid agreed to receive the compression therapy. After surgical removal, a compressive device made of acrylic resin was applied on top of...

journal_title：Journal of cutaneous medicine and surgery

authors： Hassel JC,Löser C,Koenen W,Kreuter A,Hassel AJ

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Hybrid skin adnexal tumors are common, and spiradenocylindroma is well described. OBJECTIVE:However, malignant transformation in this setting is infrequent, especially resemblance to lymphoepithelioma-like carcinoma of skin, which is not associated with Epstein-Barr virus. METHODS:A 65-year-old female pres...

journal_title：Journal of cutaneous medicine and surgery

authors： Chetty R,Perez-Ordonez B,Gilbert R,Pagedar NA,Waldron J,Ghazarian D

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Amyloidosis refers to a group of depositional diseases that are classified into two main types: systemic and localized. Large nodules of localized cutaneous amyloidosis of the nasal ala and surrounding skin are rare and the treatment is often unsatisfactory. OBJECTIVE:We report a case of rapidly enlarging, ...

journal_title：Journal of cutaneous medicine and surgery

authors： Kakani RS,Goldstein AE,Meisher I,Hoffman C

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:Erosive lichen planus is a painful and disabling disease that is frequently resistant to topical and systemic therapies. Current therapies are considered palliative rather than curative as many patients relapse after discontinuing treatment. An association has been reported between some cases of oral lichen ...

journal_title：Journal of cutaneous medicine and surgery

authors： Donovan JC,Hayes RC,Burgess K,Leong IT,Rosen CF

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:Round and oval skin wounds, like facial pigmented nevi after excision, are traditionally sutured linearly for closure, leaving significant scars, which greatly influences their appearance. OBJECTIVE:This article provides an overview of our experience using intradermal purse-string suture for round and oval ...

journal_title：Journal of cutaneous medicine and surgery

authors： Zhu JW,Wu XJ,Lu ZF,Cai SQ,Zheng M

更新日期：2012-01-01 00:00:00

abstract：:Psoriasis has been associated with a number of behavioral and systemic comorbidities, including psoriatic arthritis, anxiety, depression, obesity, hypertension, diabetes mellitus, hyperlipidemia, metabolic syndrome, smoking, cardiovascular disease, alcoholism, Crohn's disease, lymphoma, and multiple sclerosis. Many of...

journal_title：Journal of cutaneous medicine and surgery

authors： Guenther L,Gulliver W

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Systemic therapy for atopic dermatitis (AD) has been challenging with limited safe and efficacious long-term treatment options. In 2017, dupilumab was approved in the United States, Europe, and Canada as the first targeted therapy for patients with moderate-to-severe AD. Despite promising efficacy and safety...

journal_title：Journal of cutaneous medicine and surgery

authors： Jo CE,Georgakopoulos JR,Ladda M,Ighani A,Mufti A,Drucker AM,Piguet V,Yeung J

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Omalizumab is a third-line treatment for chronic spontaneous urticaria (CSU). Studies investigating the use of higher doses of omalizumab in patients unresponsive to regular doses are limited. OBJECTIVES:This study aims to investigate the effectiveness and safety of omalizumab 450 mg in CSU. METHODS:A retr...

journal_title：Journal of cutaneous medicine and surgery

authors： Salman A,Comert E

更新日期：2019-09-01 00:00:00