Abstract：
:Amisulpride is an antipsychotic available in Europe since 1990s, in Poland since 2000. Subsequent years brought to Polish market more second-generation compounds such as ziprasidone and aripiprazole. In 2018, the Agency for Health Technology Assessment and Tariff System issued positive recommendation for lurasidone in schizophrenia (Recommendation 30/2018) facilitating its entry to the market. Thanks to new molecules, therapeutic possibilities of medicines consequently rise, however, higher number of available substances of different properties brings also more dilemmas which one to pick. Since new publications of comparative drug trials, meta-analyses and systematic reviews are issued regularly, the authors present herein publications issued within last ten years focusing on amisulpride as opposed to other neuroleptics used in Poland. Although in many aspects it is equivalent to other atypical antipsychotics, it still has some advantages. Amisulpride seems to have better outcome than classic and atypical neuroleptics when it comes to depressive symptoms and predominant negative symptoms. It might also be superior to haloperidol in inducing symptomatic remission in first episode schizophrenia. Except for prolactin increase its side effects profile is favorable - it rarely leads to extrapyramidal symptoms (which are dose-dependent) and sedation. Therefore many patients accept treatment with amisulpride for its measurable clinical gains, such as improvement of positive symptoms and higher quality of life, compared to typical neuroleptics. Pharmacokinetics of amisulpride also encourage its wider use, especially when there is either a need for combined psychopharmacotherapy or comorbidity with general medical condition rises a need for somatic parallel treatment.
journal_name
Psychiatr Poljournal_title
Psychiatria polskaauthors
Hadryś T,Rymaszewska Jdoi
10.12740/PP/OnlineFirst/109129subject
Has Abstractpub_date
2020-10-31 00:00:00pages
977-989issue
5eissn
0033-2674issn
2391-5854pii
109129journal_volume
54pub_type
杂志文章,评审abstract：AIM:Combined biological and psychological basis of anorexia nervosa, related to increased self-control, low self-esteem and peculiar motivation, makes a synthetic approach still hard to achieve. The presented study assessed cognitive functions in anorectic patients with respect to both neuropsychological (test of atten...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2004-11-01 00:00:00
abstract：:Negative symptoms of schizophrenia constitute a serious diagnostic and therapeutic problem. They substantially account for the impairment of health, social functioning and quality of life whereas treatment is difficult. In this paper the development of the concept of schizophrenia and negative symptoms is presented. T...
journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：10.12740/PP/70610
更新日期：2018-04-30 00:00:00
abstract：OBJECTIVES:The aim of the study was identification of the barriers making it notably more challenging to access clinics in urban and rural communities. METHODS:The method, which was used in this study adopts the qualitative research perspective. The research tool was an interview with a standardized list of desired in...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：10.12740/PP/60345
更新日期：2017-02-26 00:00:00
abstract：:This article presents a review of the interactions between zinc and glutamate system in the pathophysiology and treatment of depression. ...
journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：
更新日期：2001-03-01 00:00:00
abstract：:58 men treated for epilepsy, average age 38.5, and their 100 children aged on average 11.2 were subjected to psychological tests adapted to patients age. Mental effectiveness test (IQ) were based on WHO criteria for Wechsler Scale. Among the epileptic patients 77.6% presented normal IQ tests results, whereas 5.6% were...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：1991-09-01 00:00:00
abstract：:The paper presents a critical review regarding the pathogenesis of schizophrenia. The neurodevelopmental theory which is now mostly recognized, needs some explanations, some elements of neurodegenerative theory are revisited. The developmental factors are confirmed as important in the pathogenesis of schizophrenia, bu...
journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：
更新日期：2005-03-01 00:00:00
abstract：:In the inauguration speech of the Congress stages of the path taken by the Polish Psychiatric Society were described in short: 1--The period from its establishment till 1939; 2--Tragic years of the war, 1939-1945, with extermination of ca. 20,000 patients and many psychiatrists; 3--Reconstruction after the war, accomp...
journal_title：Psychiatria polska
pub_type： 历史文章,杂志文章
doi：
更新日期：1999-01-01 00:00:00
abstract：:Cognitive dysfunctions are part of the symptomatology of depressive disorders but they may persist even after the patient reaches symptomatic remission. As persistent symptoms of depression, cognitive dysfunctions may inhibit and restrict the patient's functioning in many spheres and significantly impair its quality. ...
journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：10.12740/PP/OnlineFirst/105415
更新日期：2020-06-30 00:00:00
abstract：:The position of selective mutism disorder - SM - has been modified in the last edition of the classification of mental disorders DSM-5. It was removed from "Disorders of childhood and adolescence" and placed in "Anxiety disorders". This caused two important changes in the interpretation of the symptoms of selective mu...
journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：10.12740/PP/76088
更新日期：2018-04-30 00:00:00
abstract：AIM:The aim of the study was to determine the image of female-to-male transsexuals (FtM) in the opinion of women and men. Methods. The questionnaire studies were carried out in a group of 300 students. Respondents answered questions concerning their age, sex, birthplace and the questions related to different aspects of...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2012-09-01 00:00:00
abstract：:Evaluation of effects of amitriptyline, imipramine, maprotiline, mianserin , clomipramine and citalopram was performed in 84 patients (49 females and 35 males) age on average 40 years with diagnosis of affective psychosis treated in the Department of Psychiatry Medical School of Szczecin. Antidepressants independently...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：1991-05-01 00:00:00
abstract：:Many animal models in different species have been developed for mental and behavioral disorders. This review presents large animals (dog, ovine, swine, horse) as potential models of this disorders. The article was based on the researches that were published in the peer-reviewed journals. Aliterature research was carri...
journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：10.12740/PP/74304
更新日期：2017-12-30 00:00:00
abstract：:Thirty eight years after the successful clinical introduction of antidepressant agents, there has been an important progress in the knowledge and changes in thinking about the role of central serotonergic system in depression and in the mechanism of their therapeutic efficacy. Although it is not clear whether an incre...
journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：
更新日期：1996-11-01 00:00:00
abstract：:Early intervention in psychotic disorders, particularly schizophrenia, has been increasingly recognized as important by clinicians. The benefits of early intervention in schizophrenia to patients include prevention of neurobiological changes, minimization of secondary morbidity and prevention of relapse. Other benefit...
journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：
更新日期：2007-01-01 00:00:00
abstract：:The paper presents the objectives and design of an ongoing multicenter randomized, controlled trial EDEN (European Day Hospital EvaluatioN). The EDEN-study aims to evaluate the efficacy of acute psychiatric treatment in a day hospital setting in five European centres: Dresden, London, Michalovce, Prague and Wroclaw. T...
journal_title：Psychiatria polska
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2002-11-01 00:00:00
abstract：OBJECTIVES:The aim of the study was to investigate the general knowledge and attitudes towards ECT among Polish students, including students of medical faculties. Furthermore, the influence of pop-culture on society's opinion about ECT was investigated. METHODS:For this purpose, 1,370 students have been examined with ...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：10.12740/PP/109157
更新日期：2020-06-30 00:00:00
abstract：:A polish translation and the description of the clinical use of the novel screening tool in Alzheimer's disease, a "7 Minute Screen", is presented. ...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2001-05-01 00:00:00
abstract：:Psychopathological picture of depression and the conduct of some hormone tests vs the therapeutic response to thymoleptics were examined. On the grounds of some diagnostic criteria, 84 patients with affective psychosis were divided into three diagnostic groups: unipolar (DJ, n = 54) and bipolar (DD, n = 20) endogenous...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：:Up to 30% of medical students suffer from depression. They have better access to healthcare, but still receive appropriate treatment less frequently than people with depression in the general population. Most of them do not seek medical help as depression is perceived as a stigmatizing disorder, which leads to self-st...
journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：10.12740/PP/OnlineFirst/67373
更新日期：2017-06-18 00:00:00
abstract：:A group of 50 patients aged from 12 to 20 with anorexia nervosa was examined: 40 persons with a diagnosis of restricting type and 10 with binge-eating type according to DSM IV. The level of intelligence quotient (IQ) was estimated by using Wechsler Test, selfacceptation by SQ and aspiration by TAT and test of unfinish...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：1996-09-01 00:00:00
abstract：AIM:The objective of the study was to assess the relation between the occurrence of deliberate self-harm (DSH) in young patients during their psychiatric treatment and the presence of specific mental disorders, or the history of suicide attempts, the exposure to abuse and their family situation. METHOD:The studied gro...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2008-09-01 00:00:00
abstract：:Schizophrenia is an illness with a large variety of symptoms, significant variability of the individual course, and still not fully explained etiology. It is suggested that genetic, infectious and immunological factors may be involved, and neurodevelopmental, neurodegenerative and neurotransmitter hypotheses have been...
journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：10.12740/PP/114952
更新日期：2020-08-31 00:00:00
abstract：UNLABELLED:A pair of auditory stimuli presented in a 0.5 second interval cause a reduction of the P50 auditory evoked potential (P50 AEP) amplitude after the second stimuli in the pair. In some, but not all studies, a clear deficit of such P50 AEP gating was observed in schizophrenic patients. It was present constantly...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2004-05-01 00:00:00
abstract：:The studies dealt with the relationships between negative and depressive symptomatology in the active phase of paranoid schizophrenia and were aimed at distinguishing the symptoms of the greatest power discriminating either category of symptoms. ...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：:Considerations, concerning legal obligation to psychiatric treatment in case of criminal offenders declared as insane by court, are presented in the paper. Necessity of some changes in the legal system is pointed out. It is suggested that, after preventive measures in the form of compulsory psychiatric hospitalization...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：1999-03-01 00:00:00
abstract：:The evaluation of neurophysiological markers during imipramine treatment of 60 patients with endogenous depression was made. These markers were evaluated in 2 groups of patients: with cardio-vascular, and with brain circulation disturbances; both groups equal 30 subjects. During thymoleptic treatment of patients with ...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：1989-03-01 00:00:00
abstract：AIM:The aim of the study was to assess working memory and executive dysfunctions, as well as the intensity of depressive symptoms in hyperthyroid patients with Graves' disease compared to healthy persons. METHOD:Thirty (30) patients with Graves' disease (20 female, 10 male), aged 18-55, participated in the study. The ...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2008-03-01 00:00:00
abstract：OBJECTIVES:The aim of the study was to prepare the Polish adaptation of the Young Schema Questionnaire S3-PL. The scale is a self-assessment tool designed to measure 18 early maladaptive schemas. METHODS:The sample consists of 1,529 adults (927 women and 585 men), aged 18-85 years (mean age was 32 years), from non-cli...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：10.12740/PP/OnlineFirst/76541
更新日期：2018-08-24 00:00:00
abstract：:The use of non-selective monoamine oxidase inhibitors (IMAO) may be associated with the risk of addiction, which is confirmed by case studies published so far. Harmful use of antidepressants in patients with affective disorders and anxiety is not frequent, but due to the fact that in clinical practice can meet with th...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2013-01-01 00:00:00
abstract：:Monitored treatment of a depressed phase of unipolar affective disorder was conducted in 11 female patients receiving imipramine and in 12 females taking amitriptyline. Patients were randomly assigned to one of the drug and in 6 patients the drugs were switched because of the lack of response to the first used compoun...
journal_title：Psychiatria polska
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1991-05-01 00:00:00
