Abstract：
:Schizophrenia is an illness with a large variety of symptoms, significant variability of the individual course, and still not fully explained etiology. It is suggested that genetic, infectious and immunological factors may be involved, and neurodevelopmental, neurodegenerative and neurotransmitter hypotheses have been proposed. Detection of the measurable and reproducible biological indicators of the clinical picture and the course, referred to as biomarkers, may be essential to elucidate the etiopathogenic mechanism of the illness. For schizophrenia, this function may be performed by the retina of the eye and other elements of the visual pathway. The observed abnormalities are of a structural and functional nature. They concern virtually the entire visual system, and, in accordance with the neurodevelopmental theory of schizophrenia, arise at the early stages of brain formation. What is essential - the specific structure of the human eye, its translucency, lack of myelin and low concentration of glial cells provide excellent opportunities for non-invasive assessment of the microstructure and function of the central nervous system. The following paper discusses the most important changes in the visual apparatus observed in patients with schizophrenia. Particular attention was paid to retinal vascular changes, anomalies in the electroretinogram and optical coherence tomography, structural and functional disorders of cortical centers and neurochemical disorders in the cells of the visual pathway.
journal_name
Psychiatr Poljournal_title
Psychiatria polskaauthors
Wójciak P,Stopa M,Rybakowski Fdoi
10.12740/PP/114952subject
Has Abstractpub_date
2020-08-31 00:00:00pages
673-686issue
4eissn
0033-2674issn
2391-5854pii
114952journal_volume
54pub_type
杂志文章,评审abstract：:In recent years increased interest in the connection of intestinal microflora and the state of human health resulted in a great deal of research on the influence of intestinal microflora in particular on mental health, including works on affective functions of the central nervous system (CNS). Previous studies on anim...
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journal_title：Psychiatria polska
pub_type： 杂志文章,评审
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journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2001-11-01 00:00:00
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journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：1990-11-01 00:00:00
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journal_title：Psychiatria polska
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doi：
更新日期：2008-07-01 00:00:00
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journal_title：Psychiatria polska
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doi：
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journal_title：Psychiatria polska
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doi：
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journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2007-11-01 00:00:00
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journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：
更新日期：1996-05-01 00:00:00
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journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：
更新日期：2000-05-01 00:00:00
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journal_title：Psychiatria polska
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doi：
更新日期：2002-09-01 00:00:00
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journal_title：Psychiatria polska
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doi：
更新日期：2000-01-01 00:00:00
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journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
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journal_title：Psychiatria polska
pub_type： 临床试验,杂志文章,多中心研究
doi：
更新日期：2002-11-01 00:00:00
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journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：1997-05-01 00:00:00
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journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2012-03-01 00:00:00
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doi：
更新日期：2013-09-01 00:00:00
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journal_title：Psychiatria polska
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doi：
更新日期：2001-03-01 00:00:00
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journal_title：Psychiatria polska
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doi：
更新日期：2010-09-01 00:00:00
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journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：1997-09-01 00:00:00
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journal_title：Psychiatria polska
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journal_title：Psychiatria polska
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doi：
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journal_title：Psychiatria polska
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journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：
更新日期：1992-05-01 00:00:00
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journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2008-09-01 00:00:00
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journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2003-11-01 00:00:00
