Increased tumor cell multiplication after radiofrequency lesions in median hypothalamus in the mouse and rat.

abstract：:Somatostatin receptors on lactotroph cells of the anterior pituitary are positively regulated by estradiol. In the present work, we investigated whether estradiol regulation of somatostatin receptors also occurred in the female rat brain. 125I-Tyr0-DTrp8-somatostatin (125I-SRIF: 780 Ci/mM) was used as a ligand. Female...

journal_title：Neuroendocrinology

authors： Slama A,Videau C,Kordon C,Epelbaum J

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:Manipulating thyroid hormones has been shown to influence learning and memory. Although a large body of literature is available on the effects of thyroid hormone deficiency on learning and memory functions during developmental or adult-onset hypothyroidism, electrophysiological findings are limited. This lim...

journal_title：Neuroendocrinology

authors： Taşkın E,Artis AS,Bitiktas S,Dolu N,Liman N,Süer C

更新日期：2011-01-01 00:00:00

abstract：:To gain further insight into the regulation of hypothalamic TRH by thyroid hormones, we measured TRH concentration in specific hypothalamic nuclei and preproTRH mRNA levels in the anterior hypothalamus. Adult male rats were decapitated 1, 7, 14 days after thyroidectomy. Micropunches by the method of Palkovitz from sev...

journal_title：Neuroendocrinology

authors： Yamada M,Satoh T,Monden T,Murakami M,Iriuchijima T,Wilber JF,Mori M

更新日期：1992-03-01 00:00:00

abstract：:These studies investigated the effect of aging on thyroid hormone regulation of beta-endorphin in rat corpus striatum and hypothalamus. In both brain areas, basal levels of beta-endorphin declined with age. In addition, age modified the response of beta-endorphin to thyroid hormone status. Hypothyroid rats aged 6 mont...

journal_title：Neuroendocrinology

authors： Gambert SR

更新日期：1981-02-01 00:00:00

abstract：:Pregnancy and parturition are associated with opioid-mediated elevations in maternal pain thresholds. This analgesia is subserved by a spinal cord dynorphin/kappa-opiate receptor system. During gestation, elevated pain thresholds are paralleled by a significant increase in the content of dynorphin (1-17 and 1-8) in th...

journal_title：Neuroendocrinology

authors： Medina VM,Dawson-Basoa ME,Gintzler AR

更新日期：1993-09-01 00:00:00

abstract：:In rats anesthetized with sodium pentobarbital, adrenal venous blood samples were collected and analyzed for epinephrine and norepinephrine by the fluorometric method. Stimulation of the inferior fovea or adjacent areas resulted in a significant increase in epinephrine secretion. Stimulation of some other areas of the...

journal_title：Neuroendocrinology

authors： Matsui H

更新日期：1979-01-01 00:00:00

abstract：:The reuptake of dopamine into nerve terminals is the primary mechanism of inactivation of this neurotransmitter in the synaptic cleft. We report sex differences and estrous cycle variations of rat striatal dopamine uptake sites. During the estrous cycle, peak density of striatal dopamine uptake sites labelled with [3H...

journal_title：Neuroendocrinology

authors： Morissette M,Di Paolo T

更新日期：1993-07-01 00:00:00

abstract：:Structural and functional impairment of the skeletal system remains an important cause of morbidity and disability in patients with Cushing's syndrome (CS). Glucocorticoid (GC) excess inhibits bone formation and calcium absorption from the gut, increases bone resorption, and alters the secretion of gonadotropin and gr...

journal_title：Neuroendocrinology

authors： Kaltsas G,Makras P

更新日期：2010-01-01 00:00:00

abstract：:17 alpha-hydroxyprogesterone (up to 200 mug/day) and 11 beta-hydroxyandrostenedione (up to 500 mug) had no effect on PMS-induced ovulation in intact immature rats. 10 mug/day of testosterone propoinate (TP) on days 28-30 of life decreased the percent of animals ovulating and the number of ova produced; this effect per...

journal_title：Neuroendocrinology

authors： Hagino N,Goldzieher JW

更新日期：1975-01-01 00:00:00

abstract：:Somatotropes and GC cells, a GH-producing cell line, exhibit [Ca(2+)](i) oscillations that result from rhythmic Ca(2+) action potentials. Determination of this operating mode required simultaneous recording of both parameters by fura-2 imaging and patch-clamp techniques. In order to test whether patch recording induce...

journal_title：Neuroendocrinology

authors： Robert C,Tseeb V,Kordon C,Hammond C

更新日期：1999-11-01 00:00:00

abstract：:To assess whether gonadotropin-releasing hormone (GnRH) release from the hypothalamus might be altered by hyperprolactinemia in the male rat, we measured in chronically hyperprolactinemic rats the pituitary GnRH receptor content and described the pattern of luteinizing hormone (LH) release during the postcastration ri...

journal_title：Neuroendocrinology

authors： Fox SR,Hoefer MT,Bartke A,Smith MS

更新日期：1987-10-01 00:00:00

abstract：INTRODUCTION:Several studies have suggested that diet, especially one enriched in microbiota-fermented fibers or fat, regulates behavior. The underlying mechanisms are currently unknown. We previously reported that certain macronutrients (fermentable fiber and protein) regulate energy homeostasis via the activation of ...

journal_title：Neuroendocrinology

authors： Sinet F,Soty M,Zemdegs J,Guiard B,Estrada J,Malleret G,Silva M,Mithieux G,Gautier-Stein A

更新日期：2021-01-11 00:00:00

abstract：:Neurons synthesizing growth hormone releasing factor were detected by immunocytochemistry with specific antiserum against synthetic rat hypothalamic growth hormone releasing factor. Growth hormone releasing factor immunoreactive neurons which also showed tyrosine hydroxylase immunoreactivity were located in the ventro...

journal_title：Neuroendocrinology

authors： Okamura H,Murakami S,Chihara K,Nagatsu I,Ibata Y

更新日期：1985-08-01 00:00:00

abstract：:The possible implication of the amygdaloid central nucleus (ACE) of the rat in the control of ACTH secretion in response to immobilization stress was assessed. The ACTH secretion, in response to stress and/or bilateral lesions of the ACE, was correlated with the serotoninergic activity in specific hypothalamic and amy...

journal_title：Neuroendocrinology

authors： Beaulieu S,Di Paolo T,Barden N

更新日期：1986-01-01 00:00:00

abstract：:Corticotropin-releasing hormone (CRH) plays a key role in adjusting the basal and stress-activated hypothalamic-pituitary-adrenal axis (HPA). CRH is also widely distributed in extrahypothalamic circuits, where it acts as a neuroregulator to integrate the complex neuroendocrine, autonomic, and behavioral adaptive respo...

journal_title：Neuroendocrinology

authors： Bonfiglio JJ,Inda C,Refojo D,Holsboer F,Arzt E,Silberstein S

更新日期：2011-01-01 00:00:00

abstract：:Bromocriptine or other dopamine agonists are usually effective for the treatment of prolactin-secreting adenomas. Five to 18% of prolactinomas, however, do not respond to such therapy. We have shown previously that such resistance to bromocriptine correlates with reduced binding to the D2 receptor subtype of dopamine,...

journal_title：Neuroendocrinology

authors： Caccavelli L,Feron F,Morange I,Rouer E,Benarous R,Dewailly D,Jaquet P,Kordon C,Enjalbert A

更新日期：1994-09-01 00:00:00

abstract：:Serotonin, a biologically active amine, is related to carcinoid syndrome in functioning neuroendocrine tumors (NETs). Telotristat ethyl is a novel inhibitor of the tryptophan hydroxylase (TPH), a key enzyme in the production of serotonin. While its use in patients with carcinoid syndrome and uncontrolled diarrhea unde...

journal_title：Neuroendocrinology

authors： Herrera-Martínez AD,Feelders RA,Van den Dungen R,Dogan-Oruc F,van Koetsveld PM,Castaño JP,de Herder WW,Hofland LJ

更新日期：2020-01-01 00:00:00

abstract：:The level of thyroid hormone in blood has been acutely decreased by about 20--30% within 20 min with the aid of isovolemic exchange transfusion (IET) of thyroid hormone free blood cell suspension (THFBCS) in three groups of rats: (1) intact control (C); (2) median eminence (ME)-lesioned; (3) thalamus (TH)-lesioned. Th...

journal_title：Neuroendocrinology

authors： Langer P,Földes O,Mess B,Kokesová H,Gschwendtová K

更新日期：1977-01-01 00:00:00

abstract：:The expression of the alpha-subunit of the glycoprotein hormones was studied in the developing rat pituitary by in situ hybridization and immunocytochemical techniques. The alpha-subunit mRNA labelling was detected in Rathke's pouch at 12 days' gestation (E12); at E13, it was exclusively concentrated in the pars tuber...

journal_title：Neuroendocrinology

authors： Stoeckel ME,Hindelang C,Klein MJ,Poissonnier M,Félix JM

更新日期：1993-12-01 00:00:00

abstract：:To assess the neuroendocrine correlates of menstrual status migrainosus (MSM) and menstrual migraine (MM), we evaluated the prolactin (PRL) and cortisol responses to the direct central serotoninergic (5-HT) agonist meta-chlorophenylpiperazine (m-CPP) administered orally (0.5 mg/kg) during the follicular (FP: +6, +8) a...

journal_title：Neuroendocrinology

authors： Nappi RE,Sances G,Brundu B,Ghiotto N,Detaddei S,Biancardi C,Polatti F,Nappi G

更新日期：2003-07-01 00:00:00

abstract：:Parturition is initiated in sheep by an increase in the activity of the fetal hypothalamus-pituitary-adrenal (HPA) axis. Prostaglandins, known to augment the activity of this endocrine axis, have long been proposed as involved in the initiation of paturition. We have previously demonstrated that endogenously produced ...

journal_title：Neuroendocrinology

authors： Deauseault D,Giroux D,Wood CE

更新日期：2000-05-01 00:00:00

abstract：:Avian prolactin (PRL) secretion is regulated by vasoactive intestinal peptide (VIP) neurons residing in the infundibular nuclear complex (INF) of the hypothalamus. This VIPergic activity is modulated by stimulatory dopaminergic inputs. Dynorphin, serotonin (5-HT), dopamine (DA) and VIP all appear to stimulate PRL secr...

journal_title：Neuroendocrinology

authors： Youngren O,Chaiseha Y,Al-Zailaie K,Whiting S,Kang SW,El Halawani M

更新日期：2002-03-01 00:00:00

abstract：:Dehydration is a classic homeostatic stressor in rats that leads to a series of endocrine responses including stimulation of the hypothalamo-pituitary-adrenal (HPA) axis. During the last decade, it has been well established that perinatal food restriction is associated with the onset of diseases in adults. Our previou...

journal_title：Neuroendocrinology

authors： Sebaai N,Lesage J,Breton C,Vieau D,Deloof S

更新日期：2004-01-01 00:00:00

abstract：:The pituitary-adrenal axis is known to be stimulated during the acute-phase response. As cytokines play a central role in mediating the constellation of host response occurring during the acute-phase response it was of interest to assess the ability of cytokines to stimulate ACTH secretion from normal pituitary cells ...

journal_title：Neuroendocrinology

authors： Kehrer P,Turnill D,Dayer JM,Muller AF,Gaillard RC

更新日期：1988-08-01 00:00:00

abstract：:The role of endogenous opioid peptides in the control of gonadotropin-releasing hormone pulse generator activity was examined in long-term ovariectomized goats by recording the hypothalamic multiple-unit activity specifically associated with pulsatile luteinizing hormone secretion (MUA volleys). Administration of nalo...

journal_title：Neuroendocrinology

authors： Ito K,Tanaka T,Mori Y

更新日期：1993-04-01 00:00:00

abstract：:An initial study was performed to ascertain the effects of anisomycin, a reversible inhibitor of protein synthesis, on pulsatile luteinizing hormone (LH) release in adult, ovarietomized (OVX) rats. For this experiment, rats OVX 3-4 weeks earlier were fitted with indwelling atrial cannulae. On the next day (approximate...

journal_title：Neuroendocrinology

authors： DePaolo LV

更新日期：1989-07-01 00:00:00

abstract：:Overt Cushing's syndrome is a rare disorder with an annual incidence of 2-3/million of which benign adrenal adenomas account for 0.6/million. The female:male ratio is 3:1. Preliminary data indicate a high proportion of subclinical Cushing's syndrome in certain risk populations such as patients with type 2 diabetes or ...

journal_title：Neuroendocrinology

authors： Steffensen C,Bak AM,Rubeck KZ,Jørgensen JO

更新日期：2010-01-01 00:00:00

abstract：CONTEXT:Early pubertal luteinizing hormone (LH), and by inference gonadotropin-releasing hormone (GnRH), pulse secretion is marked by high nocturnal but low daytime frequency; however, the underlying mechanisms remain unclear. Plasma concentrations of progesterone, the major regulator of GnRH frequency in women, increa...

journal_title：Neuroendocrinology

authors： Collins JS,Marshall JC,McCartney CR

更新日期：2012-01-01 00:00:00

abstract：:The arcuate nucleus-median eminence complex (AM) undergoes major structural and functional changes during normal puberty or if exposed to a pulse of estradiol in the prepuberal period. Those changes are expressed by increased synaptogenesis and by a drastic alteration in the feedback control of anterior pituitary glan...

journal_title：Neuroendocrinology

authors： Rodriguez-Sierra JF,Heydorn WE,Creed GJ,Jacobowitz DM

更新日期：1987-06-01 00:00:00

abstract：:Vasoactive intestinal peptide (VIP) gene transcripts were demonstrated by RNA blot hybridization using VIP-specific RNA hybridization probes. High levels of expression were observed as early as in 16-day-old embryos. In aging rats, the VIP-mRNA levels were reduced significantly (in the cerebral cortex) as compared to ...

journal_title：Neuroendocrinology

authors： Gozes I,Schächter P,Shani Y,Giladi E

更新日期：1988-01-01 00:00:00