Discrimination learning and reversal following electrolytic lesions of the median raphe nucleus.

Abstract:

:The current study examined the effects of electrolytic median raphe lesions on the performance of several T-maze discrimination tasks. Raphe lesions were found to impair the reversal, but not the acquisition, of a learned position habit, but to be without effect on either the acquisition or reversal of simultaneous brightness discrimination task. Rats with raphe damage were severely impaired in the acquisition of either a successive brightness discrimination task or of a delayed spatial alternation task. These results are similar to those which have been reported after limbic damage, and support the view that the paramedian midbrain tegmentum may play an important role in the functioning of limbic structures.

journal_name

Physiol Behav

journal_title

Physiology & behavior

authors

Wirtshafter D,Asin KE

doi

10.1016/0031-9384(86)90223-4

subject

Has Abstract

pub_date

1986-01-01 00:00:00

pages

213-9

issue

2

eissn

0031-9384

issn

1873-507X

pii

0031-9384(86)90223-4

journal_volume

37

pub_type

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