Antagonism of the intoxicating effects of ethanol by the potent benzodiazepine receptor ligand Ro 19-4603.

abstract：:Microencephalic rats induced by methylazoxymethanol (MAM) were observed to have notable hyperactivity compared to control rats, as measured by several behavioral parameters in an automated field apparatus. Acute injection of the stimulant drug, methamphetamine (MAP), produced an increase in the incidence of locomotion...

journal_title：Brain research

authors： Watanabe M,Shimizu K,Kodama Y,Takishima K,Mamiya G,Ichinowatari N

更新日期：1995-01-23 00:00:00

abstract：:Different doses of angiotensin II (AII) or angiotensin III (AIII) microinjections into the zona incerta have been studied on drinking of rats in separate experiments during the consequent 60-min-daily-drinking period. Also, the dipsogen power of only the effective dose of AII and AIII was compared to vehicle treated r...

journal_title：Brain research

authors： Bagi EE,Fekete E,Lénárd L

更新日期：2003-07-11 00:00:00

abstract：:The effects of a sensorimotor task on ipsilateral primary motor cortex (ipsi-M1) excitability mediated via the transcallosal pathway, including the changes in short-interval intracortical inhibition (SICI) and intracortical facilitation (ICF), were examined in ten right-handed subjects. Transcranial magnetic stimulati...

journal_title：Brain research

authors： Morishita T,Ninomiya M,Uehara K,Funase K

更新日期：2011-01-31 00:00:00

abstract：:Morphological changes in neocortical somatostatin- and neuropeptide-Y-immunoreactive cells in senile dementia of the Alzheimer type (SDAT) were studied using light-microscopic immunohistochemical methods. The density of somatostatin-immunoreactive cells in the neocortex did not decrease in cases of SDAT compared with ...

journal_title：Brain research

authors： Nakamura S,Vincent SR

更新日期：1986-04-02 00:00:00

abstract：:The prostacyclin (PGI2) formation in cerebral vessels, as reflected by the difference in concentration of internal carotid arterial and internal jugular venous radioimmunoassayed 6-keto-prostaglandin F1 alpha (6-keto-PGF1 alpha), was determined under normocapnic and hypercapnic conditions in 5 patients with mild cereb...

journal_title：Brain research

authors： Uyama O,Nagatsuka K,Fukunaga R,Kusunoki M,Takano T,Yoneda S,Kimura K,Abe H

更新日期：1983-01-24 00:00:00

abstract：:Previous electrophysiological experiments have shown that brain noradrenaline neurons in the locus ceruleus are activated by thermal cutaneous stimuli. In the present study a putative involvement of excitatory amino acids (EAA) in cutaneous LC activation was analyzed. Intraventricular administration of kynurenic acid ...

journal_title：Brain research

authors： Hajós M,Engberg G

更新日期：1990-06-25 00:00:00

abstract：:Neurological problems can develop when blood glucose levels rapidly rise or fall yet there has been little experimentation at a cellular level to assess how neurophysiological change may be induced. Using intracellular recording in the rat neocortical slice preparation, we examined pyramidal neurons of layers II-III a...

journal_title：Brain research

authors： Rosen AS,Andrew RD

更新日期：1991-07-26 00:00:00

abstract：:Atropine (5 nM to 5 muM), but not D-tubocurarine or hexamethonium, enhanced the release of acetylcholine (ACh) from rat brain cortical slices exposed to high K+. The enhancement was dose-dependent, and it could be partially antagonized by oxotremorine (50-500 muM) or by dibutyryl or 8-bromo-cyclic GMP (1 mM), but not ...

journal_title：Brain research

authors： Yonehara N,Matsuda T,Saito K,Ishida H,Yoshida H

更新日期：1980-01-20 00:00:00

abstract：:Experimental allergic encephalomyelitis (EAE) was induced in young male Lewis rats. Blood-brain barrier permeability to radiotracers of different molecular sizes was studied at intervals after induction using a tissue sampling technique. The results were correlated to the clinical picture and to the histological appea...

journal_title：Brain research

authors： Juhler M,Barry DI,Offner H,Konat G,Klinken L,Paulson OB

更新日期：1984-06-08 00:00:00

abstract：:The morphology of so-called interplexiform (IP) cells immunoreactive to tyrosine hydroxylase (TH) or somatostatin (SOM) in the rat retina was described in comparison with those in the carp retina. In frozen cross-sections of the rat retina, many processes of TH-like immunoreactive cells were found to extend toward the...

journal_title：Brain research

authors： Negishi K,Kato S,Teranishi T,Kiyama H,Katayama Y,Tohyama M

更新日期：1985-10-28 00:00:00

abstract：:In this study we used two lines of transgenic mice overexpressing tumor necrosis factor alpha (TNF-alpha) in the central nervous system (CNS), one characterized by reactive gliosis, inflammatory demyelination and neurological deficits (Tg6074) the other showing no neurological or phenotypical alterations (TgK3) to inv...

journal_title：Brain research

authors： Aloe L,Properzi F,Probert L,Akassoglou K,Kassiotis G,Micera A,Fiore M

更新日期：1999-09-04 00:00:00

abstract：:Milk ejection-related bursts of action potentials recurred at fairly regular intervals during suckling in oxytocin cells of anesthetized lactating rats. Additional milk ejection-related bursts were frequently induced in response to vaginal distension. The latency for the induced response was 2.9 +/- 0.2 s and the size...

journal_title：Brain research

authors： Negoro H,Uchide K,Tadokoro Y,Honda K,Higuchi T

更新日期：1987-02-24 00:00:00

abstract：:The neurotoxin alpha-latrotoxin elicits spontaneous exocytosis of neurotransmitter from neurons and peptide hormones from endocrine cells. While the mechanism of action is not fully understood, both Ca(2+)-dependent and Ca(2+)-independent pathways participate in the facilitation of release, with the relative contribut...

journal_title：Brain research

authors： Hlubek M,Tian D,Stuenkel EL

更新日期：2003-11-28 00:00:00

abstract：:We monitored the protein expression profiles of collapsin response mediator protein 2 and 4 (CRMP2 and CRMP4) throughout cat primary visual area 17 at different postnatal ages. Single immunocytochemical stainings revealed a clear effect of cortical maturation on the spatial and laminar distribution profile of CRMP2 an...

journal_title：Brain research

authors： Cnops L,Hu TT,Burnat K,Van der Gucht E,Arckens L

更新日期：2006-05-09 00:00:00

abstract：:Stroke-prone spontaneously hypertensive rats (SHRSP) are a well-characterized, genetic model for stroke. We showed earlier that the structure and function of the tight junctions in SHRSP blood-brain barrier endothelial cells is disturbed prior to stroke. To investigate the molecular events leading to endothelial dysfu...

journal_title：Brain research

authors： Kirsch T,Wellner M,Luft FC,Haller H,Lippoldt A

更新日期：2001-08-10 00:00:00

abstract：:The retinoblastoma protein (pRb) is a key regulator of cell growth, differentiation and survival. pRb(-/-) mice show abnormal neuronal cell death in the developing brain. The function of pRb is regulated by its phosphorylation state. In this study, the phosphorylation of pRb during retinoic acid (RA)-induced neuronal ...

journal_title：Brain research

authors： Watanabe Y,Watanabe T,Kitagawa M,Taya Y,Nakayama K,Motoyama N

更新日期：1999-09-25 00:00:00

abstract：:In the present study we found that mesencephalic trigeminal (Mes-V) neurons of the rat are innervated by nitrergic fibers and that nitric oxide (NO) modifies the electrophysiological properties of these cells. Mes-V neurons were surrounded by a network of fibers that contained neuronal nitric oxide synthase (nNOS); th...

journal_title：Brain research

authors： Pose I,Sampogna S,Chase MH,Morales FR

更新日期：2003-01-17 00:00:00

abstract：:In alert cats, extracellular spikes of neurons in the medial pontine tegmentum were recorded simultaneously with whole nerve discharges of the abducens and medial rectus nerves during horizontal vestibular nystagmus. Nystagmus-related neurons were classified by their firing patterns in relation to the abrupt cessation...

journal_title：Brain research

authors： Curthoys IS,Nakao S,Markham CH

更新日期：1981-10-05 00:00:00

abstract：:Non-specific convulsive behavior induced by intrathecal (IT) morphine microinjection appears to be tonically modulated by centrifugal pathways originating within the brain since the frequency of IT morphine-induced hindlimb seizures and myoclonic twitches are both increased following spinal transection. These effects ...

journal_title：Brain research

authors： Watkins LR,Frenk H,Miller J,Mayer DJ

更新日期：1984-09-24 00:00:00

abstract：:Microinjection of bicuculline (Bic) into the unilateral putamen (Put) of the cat resulted in periodic occurrence of contralateral movement of the head (dystonia). Corresponding to this dystonic movement, repetitive spikes of the field potential occurring in the Put of the injected side and strong inhibition of the ext...

journal_title：Brain research

authors： Yamada H,Fujimoto K,Yoshida M

更新日期：1995-04-24 00:00:00

abstract：:We used whole-head magnetoencephalograpy (MEG) to record changes in neuromagnetic N100m responses generated in the left and right auditory cortex as a function of the match between visual and auditory speech signals. Stimuli were auditory-only (AO) and auditory-visual (AV) presentations of /pi/, /ti/ and /vi/. Three t...

journal_title：Brain research

authors： Davis C,Kislyuk D,Kim J,Sams M

更新日期：2008-11-25 00:00:00

abstract：:The development of glial precursor cells in the mammalian optic nerve depends on retinal ganglion cell (RGC) axons, but the signals that mediate this neuron-to-glia interaction have not been fully characterized. Sonic hedgehog (Shh) is expressed by RGCs, and we showed previously that it is required for the specificati...

journal_title：Brain research

authors： Dakubo GD,Beug ST,Mazerolle CJ,Thurig S,Wang Y,Wallace VA

更新日期：2008-09-04 00:00:00

abstract：:Neural correlates of conscious awareness can be comfortably studied when awareness of the target stimuli is a varying dependent variable in the experimental conditions where the key independent variables are kept invariant. We presented vernier targets backward masked by an invariant grating with invariant SOA. EEG da...

journal_title：Brain research

authors： Aru J,Bachmann T

更新日期：2009-05-19 00:00:00

abstract：:The neurotoxicity of ionomycin, a Ca2+ ionophore, was investigated in cultured cortical neurons from embryonic rats. While about 90% of neurons survived 2 h after exposure to ionomycin, the surviving neurons had decreased by about 30 to 40% at 16 h. Both RNA and protein synthesis inhibitors blocked this neurotoxicity....

journal_title：Brain research

authors： Takei N,Endo Y

更新日期：1994-07-25 00:00:00

abstract：:Although it is generally believed that the central projections of the retina in birds are entirely crossed, using wheat germ agglutinin-conjugated horseradish peroxidase (WGA-HRP) as an anterograde tracer, we have found that in normal posthatched chicks there is a small ipsilateral retinofugal projection to the dience...

journal_title：Brain research

authors： O'Leary DM,Gerfen CR,Cowan WM

更新日期：1983-10-01 00:00:00

abstract：:Deacetylation is a rapid clearance mechanism for ocular melatonin. We have studied the distribution of retinal melatonin deacetylase activity among vertebrate classes. Exogenous radiolabeled melatonin is metabolized by ocular tissue prepared from the amphibian Xenopus laevis, the reptile Anolis carolinensis, the teleo...

journal_title：Brain research

authors： Grace MS,Cahill GM,Besharse JC

更新日期：1991-09-13 00:00:00

abstract：:Despite a blood-brain barrier for norepinephrine, the concentration of norepinephrine in plasma and cerebrospinal fluid has been observed to be similar. This relationship between plasma and cerebrospinal fluid norepinephrine levels suggest that peripheral sympathetic neurons innervating blood vessels to brain and spin...

journal_title：Brain research

authors： Peskind ER,Raskind MA,Wilkinson CW,Flatness DE,Halter JB

更新日期：1986-03-05 00:00:00

abstract：:The contribution of opioid receptors in the nucleus accumbens to contextual and auditory fear conditioning was examined. Impairment in contextual fear conditioning was found when training occurred under accumbal infusions of the opioid receptor agonist morphine in a dose-dependent and receptor specific fashion, only w...

journal_title：Brain research

authors： Iordanova MD,Haralambous T,McNally GP,Westbrook RF

更新日期：2013-06-23 00:00:00

abstract：:The vestibular system produces a variety of compensatory responses to accelerations of the head, which include reflex responses recorded from respiratory muscle nerves of the thorax and abdomen. In order to better understand the functional significance of vestibulo-respiratory reflexes, we investigated the extent to w...

journal_title：Brain research

authors： Siniaia MS,Miller AD

更新日期：1996-10-14 00:00:00

abstract：:The periodicity of the myelin sheath in glutaraldehyde carbohydrazide (GACH) embedded tissues from three 10-day-old and two 43-day-old mice was investigated with the electron microscope. The mean repeat period and number of repeats per fiber was measured in 31-89 fibers in the trapezoid bodies, olfactory tract and sci...

journal_title：Brain research

authors： Hedley-Whyte ET,Kirschner DA

更新日期：1976-09-03 00:00:00