Abstract:
:The time course of light adaptation after intense light exposure is significantly delayed by alcohol, marijuana, and a combined dose of alcohol and marijuana. These effects were found in a double blind experiment, using 10 subjects. The experimental treatments were placebo, 0.75 ml/kg of 95% ethanol, 8 and 15 mg of delta9 tetrahydrocannabinol (THC). and 0.75 ml/kg of 95% ethanol together with 15 mg of THC. The marijuana-induced delay in recovery is doserelated. Both drugs produce delayed recovery for at least 2 h after drug ingestion. The combined alcohol and marijuana treatment produces little more than the effect produced by either drug alone, suggesting some antagonism between the drugs--a suggestion supported by a significantly lower blood alcohol level for the alcohol dose when combined with marijuana than when taken alone.
journal_name
Psychopharmacology (Berl)journal_title
Psychopharmacologyauthors
Adams AJ,Brown B,Haegerstrom-Portnoy G,Flom MC,Jones RTdoi
10.1007/BF00571413subject
Has Abstractpub_date
1978-01-31 00:00:00pages
81-6issue
1eissn
0033-3158issn
1432-2072journal_volume
56pub_type
临床试验,杂志文章,随机对照试验abstract::To test the Pavlovian conditioning model of alcohol tolerance, two groups of eight male social drinkers each received five administrations of alcohol and five administrations of an equal volume of tonic each, on an alternating basis, during the initial 10-session tolerance development phase of the study. Group 1 recei...
journal_title:Psychopharmacology
pub_type: 杂志文章
doi:10.1007/BF00310519
更新日期:1986-01-01 00:00:00
abstract::The aim of the present study was to evaluate the effects of cholinergic receptor blockade in the rat prefrontal cortex on cognitive processes. The nicotinic antagonists neuronal bungarotoxin and dihydro-beta-erythroidine and the muscarinic antagonist scopolamine were injected into the prelimbic area of the prefrontal ...
journal_title:Psychopharmacology
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abstract:RATIONALE/OBJECTIVES:Previous research has shown that ecstasy users are impaired in thinking and reasoning. The present study sought to explore the possibility that syllogistic reasoning errors in ecstasy users were due to an inability to construct a model of the premises due to working memory limitations. METHODS:Twe...
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pub_type: 杂志文章
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更新日期:2005-09-01 00:00:00
abstract::In a 4 week study of the response of neurotic outpatients to treatment with amitriptyline, diazepam, amitriptyline and diazepam, or placebo clinical and psychophysiological variables and plasma levels of the drug were assessed. Clinical improvements were substantial in all treatment groups but clear relationships betw...
journal_title:Psychopharmacology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/BF00431822
更新日期:1981-01-01 00:00:00
abstract::The effects of bromocriptine, lisuride and apomorphine on specific binding of 3H-spiroperidol to homogenates of rat caudate nucleus were studied. (+)-Butaclamol was used to define specific binding. Bromocriptine and lisuride inhibited binding markedly, in vitro and also 30 min after in vivo injection. Bromocriptine co...
journal_title:Psychopharmacology
pub_type: 杂志文章
doi:10.1007/BF00432172
更新日期:1981-01-01 00:00:00
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更新日期:1997-04-01 00:00:00
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更新日期:1997-02-01 00:00:00
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journal_title:Psychopharmacology
pub_type: 杂志文章
doi:10.1007/BF00496858
更新日期:1976-08-17 00:00:00
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journal_title:Psychopharmacology
pub_type: 杂志文章
doi:10.1007/s002130050174
更新日期:1997-01-01 00:00:00
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journal_title:Psychopharmacology
pub_type: 杂志文章
doi:10.1007/s00213-012-2814-x
更新日期:2013-01-01 00:00:00
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journal_title:Psychopharmacology
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更新日期:2019-05-01 00:00:00
abstract:RATIONALE:Consistent sex differences are observed in human drug addiction, with females often exceeding males on drug intake. However, there is still a need for animal models for some aspects of addiction such as acquisition of drug self-administration and the subsequent development of drug-seeking. OBJECTIVES:The pre...
journal_title:Psychopharmacology
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pub_type: 杂志文章,评审
doi:10.1007/BF02245133
更新日期:1992-01-01 00:00:00
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journal_title:Psychopharmacology
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更新日期:1989-01-01 00:00:00
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更新日期:2016-05-01 00:00:00
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abstract:RATIONALE:Ecstasy is a commonly used psychoactive drug with 3,4-methylenedioxymethamphetamine (MDMA) as the main content. Importantly, it has been suggested that use of MDMA may be neurotoxic particularly for serotonergic (5-hydroxytryptamine (5-HT)) neurons. In the past decades, several molecular imaging studies exami...
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pub_type: 杂志文章,评审
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更新日期:2016-10-01 00:00:00
abstract::The behavioral consequences of prolonged continuous exposure to cocaine were examined in rhesus monkeys. Operant behavior was sampled for 0.5 h every 6 h, and cocaine was continuously infused through an intravenous catheter. Cocaine (4.0-32 mg/kg/day) initially caused reductions in the rate of responding for food and ...
journal_title:Psychopharmacology
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更新日期:1988-01-01 00:00:00
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journal_title:Psychopharmacology
pub_type: 杂志文章
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更新日期:2007-12-01 00:00:00
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journal_title:Psychopharmacology
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journal_title:Psychopharmacology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2000-09-01 00:00:00
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journal_title:Psychopharmacology
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更新日期:2000-07-01 00:00:00
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更新日期:2015-01-01 00:00:00