Replication of T4 DNA in Escherichia coli treated with toluene.

abstract：:Polyoma virus particles were purified by equilibrium centrifugation in CsCl. Particles from three regions of the density gradient were examined for infectivity, for their ability to induce expanded pools of deoxyribonucleic acid (DNA) precursors, and for their ability to stimulate the synthesis of DNA. The most infect...

journal_title：Journal of virology

authors： Skoog L,Nordenskjöld BA,Lindberg U

更新日期：1970-07-01 00:00:00

abstract：:The early steps of the intracellular trafficking of human papillomavirus type 16 (HPV-16), -31, and -58 pseudovirions were studied by investigating the effects of drugs acting at defined points of endocytosis pathways on virus-like particle-mediated pseudoinfection by overexpression of a dominant-negative form of the ...

journal_title：Journal of virology

authors： Bousarghin L,Touzé A,Sizaret PY,Coursaget P

更新日期：2003-03-01 00:00:00

abstract：:The initial virus strains from as many as 12% of individuals with primary human immunodeficiency virus (HIV) infection have a 50% inhibitory concentration

journal_title：Journal of virology

authors： Leigh Brown AJ,Frost SD,Good B,Daar ES,Simon V,Markowitz M,Collier AC,Connick E,Conway B,Margolick JB,Routy JP,Corbeil J,Hellmann NS,Richman DD,Little SJ

更新日期：2004-03-01 00:00:00

abstract：:Extrachromosomal DNA purified from mink cells acutely infected with the Snyder-Theilen strain of feline sarcoma virus (FeSV) was digested with restriction endonucleases, and the DNA fragments were electrophoretically separated, transferred to a solid substrate, and hybridized with radiolabeled DNA transcripts compleme...

journal_title：Journal of virology

authors： Sherr CJ,Fedele LA,Donner L,Turek LP

更新日期：1979-12-01 00:00:00

abstract：:Porcine reproductive and respiratory syndrome (PRRS) consistently elevates the frequency of disease and mortality in young pigs. Many different secondary bacterial diseases occur in PRRS virus (PRRSV)-infected pigs. However, to date, establishing a reproducible experimental model of PRRSV infection in weaned pigs, wit...

journal_title：Journal of virology

authors： Feng W,Laster SM,Tompkins M,Brown T,Xu JS,Altier C,Gomez W,Benfield D,McCaw MB

更新日期：2001-05-01 00:00:00

abstract：UNLABELLED:Retargeting of gammaretroviral envelope proteins has shown promising results in the isolation of novel isolates with therapeutic potential. However, the optimal conditions required to obtain high-affinity retargeted envelope proteins with narrow tropism are not understood. This study highlights the advantage...

journal_title：Journal of virology

authors： Valdivieso-Torres L,Sarangi A,Whidby J,Marcotrigiano J,Roth MJ

更新日期：2015-12-30 00:00:00

abstract：:Infection with human T-cell leukemia virus type I (HTLV-I) is associated with adult T-cell lymphoma/leukemia. This disease occurs in only a small minority of people infected with HTLV-I and manifests itself many years after infection. Therefore, it appears that a fine balance exists between HTLV-I and the host T-cell ...

journal_title：Journal of virology

authors： Clark NM,Smith MJ,Hilfinger JM,Markovitz DM

更新日期：1993-09-01 00:00:00

abstract：:Heterosubtypic immunity (HSI) is defined as cross-protection to infection with an influenza A virus serotype other than the one used for primary infection. Although HSI has been thought to be mediated by serotype cross-reactive cytotoxic T lymphocytes (CTL) that recognize conserved epitopes of structural proteins, rec...

journal_title：Journal of virology

authors： Nguyen HH,Zemlin M,Ivanov II,Andrasi J,Zemlin C,Vu HL,Schelonka R,Schroeder HW Jr,Mestecky J

更新日期：2007-09-01 00:00:00

abstract：:The nondefective adenovirus 2 (Ad2)-simian virus 40 (SV40) hybrid virus, Ad2(+)ND(1), differs from the defective Ad-SV40 hybrid populations previously described, in that this hybrid virus can replicate without the aid of nonhybrid adenovirus helper. Consequently, the deoxyribonucleic acid (DNA) from this virus, which ...

journal_title：Journal of virology

authors： Crumpacker CS,Henry PH,Kakefuda T,Rowe WP,Levin MJ,Lewis AM Jr

更新日期：1971-03-01 00:00:00

abstract：:An immunochemical analysis of the hemagglutinin (VP4) of the simian rotavirus SA11 was performed to better understand the structure and function of this molecule. Following immunization of mice with double-shelled virus particles and VP4-enriched fractions from CsCl gradients, a battery of anti-SA11 hybridomas was gen...

journal_title：Journal of virology

authors： Burns JW,Greenberg HB,Shaw RD,Estes MK

更新日期：1988-06-01 00:00:00

abstract：:Proteolytic processing of the dengue virus polyprotein is mediated by host cell proteases and the virus-encoded NS2B-NS3 two-component protease. The NS3 protease represents an attractive target for the development of antiviral inhibitors. The three-dimensional structure of the NS3 protease domain has been determined, ...

journal_title：Journal of virology

authors： Niyomrattanakit P,Winoyanuwattikun P,Chanprapaph S,Angsuthanasombat C,Panyim S,Katzenmeier G

更新日期：2004-12-01 00:00:00

abstract：:We established a novel experimental model for human T-cell leukemia virus type 1 (HTLV-1)-induced tumor using NOD-SCID/gammac(null) (NOG) mice. This model is very useful for investigating the mechanism of tumorigenesis and malignant cell growth of adult T-cell leukemia (ATL)/lymphoma, which still remains unclear. Nine...

journal_title：Journal of virology

authors： Dewan MZ,Terashima K,Taruishi M,Hasegawa H,Ito M,Tanaka Y,Mori N,Sata T,Koyanagi Y,Maeda M,Kubuki Y,Okayama A,Fujii M,Yamamoto N

更新日期：2003-05-01 00:00:00

abstract：:Poliovirus proteins, except P3-7c, are associated with the endoplasmic reticulum after extraction of the cytoplasm and centrifugation of membranes to equilibrium in sucrose gradients. Proteins P3-2, P2-X, and P3-9 are found preferentially among the rough endoplasmic reticulum, whereas P3-7c is located in smooth endopl...

journal_title：Journal of virology

authors： Tershak DR

更新日期：1984-12-01 00:00:00

abstract：:We investigated properties of the rotavirus genome segment 11 protein. A rotavirus SA11 genome segment 11 cDNA which contains the entire coding region was sequenced and inserted into the baculovirus transfer vector pVL941. Recombinants containing gene 11 cDNA were selected, and the gene 11 product expressed in Spodopt...

journal_title：Journal of virology

authors： Welch SK,Crawford SE,Estes MK

更新日期：1989-09-01 00:00:00

abstract：:Primary HIV-1 infection (PHI) is marked by a flu-like syndrome and high levels of viremia that decrease to a viral set point with the first emergence of virus-specific CD8+ T-cell responses. Here, we investigated in a large cohort of 527 subjects the immunodominance pattern of the first virus-specific cytotoxic T-lymp...

journal_title：Journal of virology

authors： Streeck H,Jolin JS,Qi Y,Yassine-Diab B,Johnson RC,Kwon DS,Addo MM,Brumme C,Routy JP,Little S,Jessen HK,Kelleher AD,Hecht FM,Sekaly RP,Rosenberg ES,Walker BD,Carrington M,Altfeld M

更新日期：2009-08-01 00:00:00

abstract：:Recent reports suggest that human genogroup II genotype 17 (GII.17) noroviruses are increasing in prevalence. We analyzed the evolutionary changes of three GII.17 capsid protruding (P) domains. We found that the GII.17 P domains had little cross-reactivity with antisera raised against the dominant GII.4 strains. X-ray...

journal_title：Journal of virology

authors： Singh BK,Koromyslova A,Hefele L,Gürth C,Hansman GS

更新日期：2015-12-23 00:00:00

abstract：:The Epstein-Barr virus (EBV) genome contains an open reading frame, BHRF1, that encodes a presumptive membrane protein with sequence similarity to the proto-oncogene bcl2, which is linked to human B-cell follicular lymphoma. Potential roles for BHRF1 in EBV's ability to growth transform human B cells and to replicate ...

journal_title：Journal of virology

authors： Lee MA,Yates JL

更新日期：1992-04-01 00:00:00

abstract：:Structural proteins of temperature-sensitive (ts) mutants of vesicular stomatitis virus, Indiana serotype, were compared with those of wild-type and revertant virions by electrophoresis on polyacrylamide gels of partial digests with Staphylococcus aureus V8 protease. Mutants of complementation groups III (tsG31 and ts...

journal_title：Journal of virology

authors： Metzel PS,Reichmann ME

更新日期：1981-01-01 00:00:00

abstract：:Some retroviruses with an extended repeat (R) region encode the polyadenylation signal within the R region such that this signal is present at both the 5' and 3' ends of the viral transcript. This necessitates differential regulation to either repress recognition of the 5' polyadenylation signal or enhance usage of th...

journal_title：Journal of virology

authors： Das AT,Klaver B,Berkhout B

更新日期：1999-01-01 00:00:00

abstract：:Several lines of evidence suggest that various cofactors may be required for prion replication. PrP binds to polyanions, and RNAs were shown to promote the conversion of PrP(C) into PrP(Sc) in vitro. In the present study, we investigated strain-specific differences in RNA requirement during in vitro conversion and the...

journal_title：Journal of virology

authors： Saá P,Sferrazza GF,Ottenberg G,Oelschlegel AM,Dorsey K,Lasmézas CI

更新日期：2012-10-01 00:00:00

abstract：:The activity of uracil-DNA glycosylase in Escherichia coli decreases dramatically to less than 10% of its original level after infection of the cells by phage T5. Phage-induced protein synthesis is required for this inhibition to occur, and the inhibition is induced by a mutant capable of injecting only the first 8% o...

journal_title：Journal of virology

authors： Warner HR,Johnson LK,Snustad DP

更新日期：1980-01-01 00:00:00

abstract：:A gene encoding a homolog of glycoprotein B of herpes simplex virus (gB homolog) has been identified on the Marek's disease virus (MDV) genome (L. J. N. Ross, M. Sanderson, S. D. Scott, M. M. Binns, T. Doel, and B. Milne, J. Gen. Virol. 70:1789-1804, 1989); however, the molecular and immunological characteristics of t...

journal_title：Journal of virology

authors： Niikura M,Matsuura Y,Endoh D,Onuma M,Mikami T

更新日期：1992-05-01 00:00:00

abstract：:Herpes simplex virus (HSV) codes for several envelope glycoproteins, including glycoprotein G-2 (gG-2) of HSV type 2 (HSV-2), which are dispensable for replication in cell culture. However, clinical isolates which are deficient in such proteins occur rarely. We describe here five clinical HSV-2 isolates which were fou...

journal_title：Journal of virology

authors： Liljeqvist JA,Svennerholm B,Bergström T

更新日期：1999-12-01 00:00:00

abstract：:Influenza viruses and rhinoviruses are responsible for a large number of acute respiratory viral infections in human populations and are detected as copathogens within hosts. Clinical and epidemiological studies suggest that coinfection by rhinovirus and influenza virus may reduce disease severity and that they may al...

journal_title：Journal of virology

authors： Gonzalez AJ,Ijezie EC,Balemba OB,Miura TA

更新日期：2018-11-12 00:00:00

abstract：:Characterizations of genetic variations among hepatitis delta virus (HDV) isolates have focused principally on phylogenetic analysis of sequences, which vary by 30 to 40% among three genotypes and about 10 to 15% among isolates of the same genotype. The significance of the sequence differences has been unclear but cou...

journal_title：Journal of virology

authors： Casey JL,Gerin JL

更新日期：1998-04-01 00:00:00

abstract：:Induction of virus-specific T-cell responses in mucosal as well as systemic compartments of the immune system is likely to be a critical feature of an effective AIDS vaccine. We investigated whether virus-specific CD8(+) lymphocytes induced in rhesus macaques by immunization with attenuated simian immunodeficiency vir...

journal_title：Journal of virology

authors： Cromwell MA,Veazey RS,Altman JD,Mansfield KG,Glickman R,Allen TM,Watkins DI,Lackner AA,Johnson RP

更新日期：2000-09-01 00:00:00

abstract：:The simian B-lymphotropic papovavirus (LPV) encodes a large tumor antigen (T antigen) which is 45% identical to both the simian virus 40 (SV40) and the polyomavirus (PyV) large T antigens. In transgenic mice, the transforming properties of the LPV T antigen are similar to those of the SV40 T antigen. However, little i...

journal_title：Journal of virology

authors： Symonds H,Chen JD,Van Dyke T

更新日期：1991-10-01 00:00:00

abstract：:Rift Valley fever virus (RVFV), a phlebovirus of the Bunyaviridae family, is an arthropod-borne virus which emerges periodically throughout Africa, emphasizing that it poses a major threat for animal and human populations. To assess the genetic variability of RVFV, several isolates from diverse localities of Africa we...

journal_title：Journal of virology

authors： Sall AA,Zanotto PM,Sene OK,Zeller HG,Digoutte JP,Thiongane Y,Bouloy M

更新日期：1999-10-01 00:00:00

abstract：:We have constructed new murine leukemia virus (MLV)-based vectors (TIN vectors) which, following integration, contain human immunodeficiency virus (HIV) type 1 U3 and R sequences in place of the MLV U3 and R regions. This provides, for the first time, single transcriptional unit retroviral vectors under the control of...

journal_title：Journal of virology

authors： Cannon PM,Kim N,Kingsman SM,Kingsman AJ

更新日期：1996-11-01 00:00:00

abstract：:Although monkey B virus (herpesvirus simiae; BV) is common in all macaque species, fatal human infections appear to be associated with exposure to rhesus macaques (Macaca mulatta), suggesting that BV isolates from rhesus monkeys may be more lethal to nonmacaques than are BV strains indigenous to other macaque species....

journal_title：Journal of virology

authors： Smith AL,Black DH,Eberle R

更新日期：1998-11-01 00:00:00