Morphology of a virus of blue-green algae and properties of its deoxyribonucleic acid.

abstract：:Mlvi-1 defines a locus of proviral integration in rat thymomas induced by Moloney murine leukemia virus. pvt-1/Mis-1 represents an independently identified locus which becomes rearranged either by chromosomal translocation in murine plasmacytomas or by provirus insertion in retrovirus-induced murine and rat thymic lym...

journal_title：Journal of virology

authors： Koehne CF,Lazo PA,Alves K,Lee JS,Tsichlis PN,O'Donnell PV

更新日期：1989-05-01 00:00:00

abstract：:Recombinant adenovirus serotype 5 (rAd5) vector-based vaccines are currently being developed for both human immunodeficiency virus type 1 and other pathogens. The potential limitations associated with rAd5 vectors, however, have led to the construction of novel rAd vectors derived from rare Ad serotypes. Several rare ...

journal_title：Journal of virology

authors： Abbink P,Lemckert AA,Ewald BA,Lynch DM,Denholtz M,Smits S,Holterman L,Damen I,Vogels R,Thorner AR,O'Brien KL,Carville A,Mansfield KG,Goudsmit J,Havenga MJ,Barouch DH

更新日期：2007-05-01 00:00:00

abstract：:The transcription map of the Aedes albopictus densovirus (AalDNV) brevidensovirus was identified by Northern blotting, rapid amplification of cDNA ends (RACE) analysis, and RNase protection assays. AalDNV produced mRNAs of 3,359 (NS1), 3,345 (NS2), and 1,246 (VP) nucleotides. The two overlapping P7/7.4 NS promoters em...

journal_title：Journal of virology

authors： Pham HT,Jousset FX,Perreault J,Shike H,Szelei J,Bergoin M,Tijssen P

更新日期：2013-09-01 00:00:00

abstract：:Although the major component of the prion is believed to be the oligomer of PrP(Sc), little information is available concerning regions on the PrP(Sc) molecule that affect prion infectivity. During the analysis of PrP(Sc) molecules from various prion strains, we found that PrP(Sc) of the Chandler strain showed a uniqu...

journal_title：Journal of virology

authors： Shindoh R,Kim CL,Song CH,Hasebe R,Horiuchi M

更新日期：2009-04-01 00:00:00

abstract：UNLABELLED:Pattern recognition receptors (PRR) sense certain molecular patterns uniquely expressed by pathogens. Retinoic-acid-inducible gene I (RIG-I) is a cytosolic PRR that senses viral nucleic acids and induces innate immune activation and secretion of type I interferons (IFNs). Here, using influenza vaccine antige...

journal_title：Journal of virology

authors： Kulkarni RR,Rasheed MA,Bhaumik SK,Ranjan P,Cao W,Davis C,Marisetti K,Thomas S,Gangappa S,Sambhara S,Murali-Krishna K

更新日期：2014-12-01 00:00:00

abstract：:UR2 is a newly characterized avian sarcoma virus whose genome contains a unique sequence that is not related to the sequences of other avian sarcoma virus transforming genes thus far identified. This unique sequence, termed ros, is fused to part of the viral gag gene. The product of the fused gag-ros gene of UR2 is a ...

journal_title：Journal of virology

authors： Feldman RA,Wang LH,Hanafusa H,Balduzzi PC

更新日期：1982-04-01 00:00:00

abstract：:The E6 oncoprotein of high-risk human papillomavirus type 16 (HPV16) interacts with several nuclear transcription factors and coactivators in addition to cytoplasmic proteins, suggesting that nuclear import of HPV16 E6 plays a role in the cellular transformation process. In this study we have investigated the nuclear ...

journal_title：Journal of virology

authors： Le Roux LG,Moroianu J

更新日期：2003-02-01 00:00:00

abstract：:A particles with the diameter of 70 to 80 nm were isolated from the cytoplasm of HEp-2, HeLa, and AO cells producing oncornavirus of Mason-Pfizer-like type. Most of the A particles banded at 1.23 to 1.24 g/ml, whereas 3 to 10% banded at 1.29 g/ml in equilibrium sucrose gradients. They banded at 1.30 g/ml in CsCl gradi...

journal_title：Journal of virology

authors： Bukrinskaya AG,Miller GG,Lebedeva EN,Agaphonova LV,Masurenko NN,Ilyin KV

更新日期：1974-10-01 00:00:00

abstract：:The human immunodeficiency virus type 1 (HIV-1) Tat protein is essential for viral replication and stimulates transcription of the integrated provirus by recruiting the kinase complex TAK/P-TEFb, composed of cyclin T1 (CycT1) and Cdk9, to the viral TAR RNA element. TAK/P-TEFb phosphorylates the RNA polymerase II compl...

journal_title：Journal of virology

authors： Liou LY,Herrmann CH,Rice AP

更新日期：2002-11-01 00:00:00

abstract：:In polarized epithelial cells, the vesicular stomatitis virus glycoprotein is segregated to the basolateral plasma membrane, where budding of the virus takes place. We have generated recombinant viruses expressing mutant glycoproteins without the basolateral-membrane-targeting signal in the cytoplasmic domain. Though ...

journal_title：Journal of virology

authors： Zimmer G,Zimmer KP,Trotz I,Herrler G

更新日期：2002-04-01 00:00:00

abstract：:During the late phase of simian virus 40 infections of CV1 cells, the relative ratios of the spliced to the unspliced RNA molecules of the 19S family were measured. In the cytoplasm, unspliced 19S RNA represented between 1 and 2% of spliced 19S RNA. This ratio could be altered by the use of different methods of RNA ex...

journal_title：Journal of virology

authors： Villarreal LP,Jovanovich S

更新日期：1980-11-01 00:00:00

abstract：:Human cytomegalovirus (HCMV) is the most common congenitally transmitted pathogen worldwide, impacting an estimated 1 million newborns annually. Congenital HCMV (cCMV) infection is a major global contributor to long-term neurologic deficits, including deafness, microcephaly, and neurodevelopmental delay, as well as to...

journal_title：Journal of virology

authors： Permar SR,Schleiss MR,Plotkin SA

更新日期：2018-03-14 00:00:00

abstract：:Hemagglutinin (HA) of H3N2/1968 pandemic influenza viruses differs from the putative avian precursor by seven amino acid substitutions. Substitutions Q226L and G228S are known to be essential for adaptation of avian HA to mammals. We found that introduction of avian-virus-like amino acids at five other HA positions (p...

journal_title：Journal of virology

authors： Van Poucke S,Doedt J,Baumann J,Qiu Y,Matrosovich T,Klenk HD,Van Reeth K,Matrosovich M

更新日期：2015-12-01 00:00:00

abstract：:Recent studies indicate that expansion of NKG2C-positive natural killer (NK) cells is associated with human cytomegalovirus (HCMV); however, their activity in response to HCMV-infected cells remains unclear. We show that NKG2C(hi) CD57(hi) NK cells gated on CD3(neg) CD56(dim) cells can be phenotypically identified as ...

journal_title：Journal of virology

authors： Wu Z,Sinzger C,Frascaroli G,Reichel J,Bayer C,Wang L,Schirmbeck R,Mertens T

更新日期：2013-07-01 00:00:00

abstract：:The Sydney Blood Bank Cohort (SBBC) consists of eight blood transfusion recipients infected with nef-attenuated human immunodeficiency virus type 1 (HIV-1) acquired from a single donor. Here, we show that viral phenotypes and antibody responses differ considerably between individual cohort members, despite the single ...

journal_title：Journal of virology

authors： Verity EE,Zotos D,Wilson K,Chatfield C,Lawson VA,Dwyer DE,Cunningham A,Learmont J,Dyer W,Sullivan J,Churchill M,Wesselingh SL,Gabuzda D,Gorry PR,McPhee DA

更新日期：2007-09-01 00:00:00

abstract：:Infection of mouse L-cell spinner cultures by vesicular stomatitis virus (VSV) effected the selective translation of viral mRNA by 4h after viral adsorption. Cell-free systems prepared from mock- and VSV-infected cells reflected this phenomenon; protein synthesis was reduced in the virus-infected cell lysate by approx...

journal_title：Journal of virology

authors： Centrella M,Lucas-Lenard J

更新日期：1982-03-01 00:00:00

abstract：:N(pro) is a multifunctional autoprotease unique to pestiviruses. The interacting partners of the N(pro) protein of classical swine fever virus (CSFV), a swine pestivirus, have been insufficiently defined. Using a yeast two-hybrid screen, we identified poly(C)-binding protein 1 (PCBP1) as a novel interacting partner of...

journal_title：Journal of virology

authors： Li D,Li S,Sun Y,Dong H,Li Y,Zhao B,Guo D,Weng C,Qiu HJ

更新日期：2013-02-01 00:00:00

abstract：:Herpesvirus nucleocapsids are translocated from their assembly site in the nucleus to the cytosol by acquisition of a primary envelope at the inner nuclear membrane which subsequently fuses with the outer nuclear membrane. This transport through the nuclear envelope requires homologs of the conserved herpesviral pUL31...

journal_title：Journal of virology

authors： Grimm KS,Klupp BG,Granzow H,Müller FM,Fuchs W,Mettenleiter TC

更新日期：2012-06-01 00:00:00

abstract：UNLABELLED:Influenza A viruses (IAVs) rely on host factors to support their life cycle, as viral proteins hijack or interact with cellular proteins to execute their functions. Identification and understanding of these factors would increase our knowledge of the molecular mechanisms manipulated by the viruses. In this s...

journal_title：Journal of virology

authors： Gao S,Wu J,Liu RY,Li J,Song L,Teng Y,Sheng C,Liu D,Yao C,Chen H,Jiang W,Chen S,Huang W

更新日期：2015-01-01 00:00:00

abstract：:The protease (PR) from human immunodeficiency virus (HIV) is essential for viral replication: this aspartyl protease, active only as a dimer, is responsible for cleavage of the viral polyprotein precursors (Gag and Gag-Pol), to release the functional mature proteins. In this work, we have studied the structure-functio...

journal_title：Journal of virology

authors： Dautin N,Karimova G,Ladant D

更新日期：2003-08-01 00:00:00

abstract：:PLC/PRF/5, a tissue culture cell line isolated from a human hepatocellular carcinoma and producing hepatitis B surface antigen, was studied for the presence of hepatitis B virus (HBV)-specific DNA and RNA. PLC/PRF/5 cell DNA accelerated the rate of reassociation of HBV [32P]DNA, and quantitative experiments indicated ...

journal_title：Journal of virology

authors： Marion PL,Salazar FH,Alexander JJ,Robinson WS

更新日期：1980-02-01 00:00:00

abstract：:Replication of the genomic RNA of severe acute respiratory syndrome coronavirus (SARS-CoV) is mediated by replicase polyproteins that are processed by two viral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro). Previously, we showed that SARS-CoV PLpro processes the replicase polyprotein at three ...

journal_title：Journal of virology

authors： Barretto N,Jukneliene D,Ratia K,Chen Z,Mesecar AD,Baker SC

更新日期：2005-12-01 00:00:00

abstract：:Zyxin, a focal adhesion molecule, interacts specifically with the E6 protein from human papillomavirus (HPV) type 6 in a yeast two-hybrid screen of a cDNA library prepared from human keratinocytes. Zyxin does not interact significantly with E6 proteins from HPV types 11, 16, or 18. The interaction was confirmed by in ...

journal_title：Journal of virology

authors： Degenhardt YY,Silverstein S

更新日期：2001-12-01 00:00:00

abstract：:Primary telencephalic cultures derived from neonatal Wistar Furth rats were able to support the growth of coronavirus JHM if a viable neuronal population was maintained. This occurred under serum-free defined, but not serum-supplemented, growth conditions. The importance of neurons in establishing infections in mixed ...

journal_title：Journal of virology

authors： Pasick JM,Dales S

更新日期：1991-09-01 00:00:00

abstract：:Reactivations of persistent viral infections pose a significant medical problem in immunocompromised cancer, transplant, and AIDS patients, yet little is known about how persistent viral infections are immunologically controlled. Here we describe a mouse model for investigating the role of the immune response in contr...

journal_title：Journal of virology

authors： Hasenkrug KJ,Brooks DM,Dittmer U

更新日期：1998-08-01 00:00:00

abstract：:In vitro studies have suggested an important role for the minor capsid protein (VP1) unique region and the junction between VP1 and the major capsid protein (VP2) in the neutralizing immune response to B19 parvovirus. We investigated the role of the NH2-terminal region of the major structural protein in capsid structu...

journal_title：Journal of virology

authors： Kawase M,Momoeda M,Young NS,Kajigaya S

更新日期：1995-10-01 00:00:00

abstract：:The activity of phosphatidylinositol 4-kinase class III beta (PI4KIIIβ) has been shown to be required for the replication of multiple picornaviruses; however, it is unclear whether a physical association between PI4KIIIβ and the viral replication machinery exists and, if it does, whether association is necessary. We e...

journal_title：Journal of virology

authors： Greninger AL,Knudsen GM,Betegon M,Burlingame AL,Derisi JL

更新日期：2012-04-01 00:00:00

abstract：:Capsid (core) assembly is essential for hepatitis B virus (HBV) replication. We hypothesize that assembly kinetics and stability are tuned for optimal viral replication, not maximal assembly. Assembly effectors (AEfs) are small molecules proposed to disrupt this balance by inappropriately enhancing core assembly. Guid...

journal_title：Journal of virology

authors： Tan Z,Maguire ML,Loeb DD,Zlotnick A

更新日期：2013-03-01 00:00:00

abstract：:We have obtained a polyclonal antiserum, N-BE, against the denatured, amino-terminal half of the measles virus (MV) nucleocapsid (N) protein and a monoclonal antibody (MAb), N46, which recognizes a conformation-dependent epitope in the same region. Amino acid residues 23 to 239 were required and sufficient for the for...

journal_title：Journal of virology

authors： Gombart AF,Hirano A,Wong TC

更新日期：1993-07-01 00:00:00

abstract：:The susceptibility to tumors induced by raf and raf/myc retroviruses was investigated in BALB/c, C57BL/6, (BALB/c x C57BL/6)F1 and (BALB/c x C57BL/6) backcross mice. Newborn mice were susceptible to neoplasms generated by both viruses, but resistance to raf-induced leukemia developed rapidly in all mice as they mature...

journal_title：Journal of virology

authors： Klinken SP,Hartley JW,Fredrickson TN,Rapp UR,Morse HC 3rd

更新日期：1989-05-01 00:00:00