Transient induction of cyclin T1 during human macrophage differentiation regulates human immunodeficiency virus type 1 Tat transactivation function.

abstract：:This paper describes Q beta noninfectious particles produced at 41 degrees C in a streptomycin-resistant Escherichia coli mutant which is temperature sensitive for suppression of a nonsense codon. The noninfectious particles resembled Q beta under the electron microscope and contained coat protein molecules in an amou...

journal_title：Journal of virology

authors： Engelberg-Kulka H,Israeli-Reches M,Dekel L,Friedmann A

更新日期：1979-03-01 00:00:00

abstract：:Reoviruses are a leading model for understanding cellular mechanisms of virus-induced apoptosis. Reoviruses induce apoptosis in multiple cell lines in vitro, and apoptosis plays a key role in virus-induced tissue injury of the heart and brain in vivo. The activation of transcription factors NF-kappaB and c-Jun are key...

journal_title：Journal of virology

authors： DeBiasi RL,Clarke P,Meintzer S,Jotte R,Kleinschmidt-Demasters BK,Johnson GL,Tyler KL

更新日期：2003-08-01 00:00:00

abstract：:The protein kinase inhibitor H7 blocks influenza virus replication, inhibits production of the matrix protein (M1), and leads to a retention of the viral ribonucleoproteins (vRNPs) in the nucleus at late times of infection (K. Martin and A. Helenius, Cell 67:117-130, 1991). We show here that production of assembled vR...

journal_title：Journal of virology

authors： Bui M,Wills EG,Helenius A,Whittaker GR

更新日期：2000-02-01 00:00:00

abstract：:Incorporation of the vaccinia virus A36R protein into the outer membrane of intracellular enveloped virions (IEV) is dependent on expression of the A33R protein. Possible interactions of the 200-amino-acid cytoplasmic domain of the A36R protein with itself or with the cytoplasmic domain of the A33R, A34R, B5R, or F12L...

journal_title：Journal of virology

authors： Ward BM,Weisberg AS,Moss B

更新日期：2003-04-01 00:00:00

abstract：:We have identified nucleotide sequences that regulate transcription in both a cell-type-specific and general manner in the long terminal repeat of the MCF13 murine leukemia virus. Besides the enhancer element, we have observed that the region between the enhancer and promoter (DEN) has a profound effect on transcripti...

journal_title：Journal of virology

authors： Tupper JC,Chen H,Hays EF,Bristol GC,Yoshimura FK

更新日期：1992-12-01 00:00:00

abstract：:Regulatory elements interacting with DNA-binding proteins have been investigated in the promoter sequence of the early PE38 gene in the Autographa californica nuclear polyhedrosis virus (AcNPV). A GATA motif located 50 nucleotides upstream of the PE38 transcriptional start site is recognized differentially in the cour...

journal_title：Journal of virology

authors： Krappa R,Behn-Krappa A,Jahnel F,Doerfler W,Knebel-Mörsdorf D

更新日期：1992-06-01 00:00:00

abstract：:Human keratinocytes immortalized by full-length or early-region simian virus 40 (SV40) DNA grow in agarose and form tumors in nude mice, in contrast to keratinocytes immortalized by the E6/E7 genes of human papillomaviruses. To determine the molecular basis for this biological difference in growth, we have used the in...

journal_title：Journal of virology

authors： Yuan H,Veldman T,Rundell K,Schlegel R

更新日期：2002-11-01 00:00:00

abstract：:Recently, we demonstrated that inverted repeat sequences inserted into first-generation adenovirus (Ad) vector genomes mediate precise genomic rearrangements resulting in vector genomes devoid of all viral genes that are efficiently packaged into functional Ad capsids. As a specific application of this finding, we gen...

journal_title：Journal of virology

authors： Lieber A,Steinwaerder DS,Carlson CA,Kay MA

更新日期：1999-11-01 00:00:00

abstract：:Neurons of the sensory ganglia are the major site of varicella-zoster virus (VZV) latency and may undergo productive infection during reactivation. Although the VZV glycoprotein E/glycoprotein I (gE/gI) complex is known to be critical for neurovirulence, few studies have assessed the roles of these proteins during inf...

journal_title：Journal of virology

authors： Christensen J,Steain M,Slobedman B,Abendroth A

更新日期：2013-12-01 00:00:00

abstract：:The Friend or Moloney mink cell focus-forming (MCF) virus encodes a recombinant-type envelope glycoprotein, gp70, that is closely related to the membrane glycoprotein, gp55, of Friend spleen focus-forming virus (SFFV). We have shown previously that gp55 has the ability to activate cell growth by binding to the cellula...

journal_title：Journal of virology

authors： Li JP,Baltimore D

更新日期：1991-05-01 00:00:00

abstract：:The 86-kDa IE2 protein (IE86) of human cytomegalovirus (HCMV) can act as both an activator and a repressor of gene expression. The mechanisms for both of these functions are not well defined. It has recently been demonstrated that this protein has sequence-specific DNA binding properties: it interacts directly with a ...

journal_title：Journal of virology

authors： Arlt H,Lang D,Gebert S,Stamminger T

更新日期：1994-07-01 00:00:00

abstract：UNLABELLED:CD4+ T cells play a pivotal role in the control of chronic viral infections. Recently, nontraditional CD4+ T cell functions beyond helper effects have been described, and a role for cytolytic CD4+ T cells in the control of HIV infection has been suggested. We define here the transcriptional, phenotypic, and ...

journal_title：Journal of virology

authors： Johnson S,Eller M,Teigler JE,Maloveste SM,Schultz BT,Soghoian DZ,Lu R,Oster AF,Chenine AL,Alter G,Dittmer U,Marovich M,Robb ML,Michael NL,Bolton D,Streeck H

更新日期：2015-08-01 00:00:00

abstract：:Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that has been responsible for an epidemic outbreak of unprecedented magnitude in recent years. Since then, significant efforts have been made to better understand the biology of this virus, but we still have poor knowledge of CHIKV interactions with host c...

journal_title：Journal of virology

authors： Bouraï M,Lucas-Hourani M,Gad HH,Drosten C,Jacob Y,Tafforeau L,Cassonnet P,Jones LM,Judith D,Couderc T,Lecuit M,André P,Kümmerer BM,Lotteau V,Desprès P,Tangy F,Vidalain PO

更新日期：2012-03-01 00:00:00

abstract：:We have studied protein synthesis in cultured cells infected with the six noncytopathic (nc) mutants of the Australia-Victoria strain (AV-WT) of Newcastle disease virus and their plaque-forming revertants. Virus-specific polypeptides accumulated at 30 to 63% of wild-type levels in nc mutant-infected cells and between ...

journal_title：Journal of virology

authors： Madansky CH,Bratt MA

更新日期：1981-12-01 00:00:00

abstract：:Since most human immunodeficiency virus (HIV) infections are initiated following mucosal exposure to the virus, the anatomic containment or abortion of an HIV infection is likely to require vaccine-elicited cellular immune responses in those mucosal sites. Studying vaccine-elicited mucosal immune responses has been pr...

journal_title：Journal of virology

authors： Baig J,Levy DB,McKay PF,Schmitz JE,Santra S,Subbramanian RA,Kuroda MJ,Lifton MA,Gorgone DA,Wyatt LS,Moss B,Huang Y,Chakrabarti BK,Xu L,Kong WP,Yang ZY,Mascola JR,Nabel GJ,Carville A,Lackner AA,Veazey RS,Letvin N

更新日期：2002-11-01 00:00:00

abstract：:LA3382 is a temperature-sensitive replication-defective mutant of Rous sarcoma virus that contains four active mutations. In this study we performed experiments to determine the biochemical defect that blocks the synthesis of infections virus late in the replication cycle. At the nonpermissive temperature (41 degrees ...

journal_title：Journal of virology

authors： Hardwick JM,Hunter E

更新日期：1981-12-01 00:00:00

abstract：UNLABELLED:Influenza A virus (IAV) entry is a multistep process that requires the interaction of the virus with numerous host factors. In this study, we demonstrate that prolidase (PEPD) is a cellular factor required by IAV for successful entry into target cells. PEPD was selected as a candidate during an entry screen ...

journal_title：Journal of virology

authors： Pohl MO,Edinger TO,Stertz S

更新日期：2014-10-01 00:00:00

abstract：:A ribonucleic acid (RNA)-dependent RNA polymerase was induced in chick embryo fibroblast cells after infection with Sendai virus (parainfluenza 1 virus). The enzyme was associated with the microsomal fraction of infected cells and reached maximum detectable activity at 18 hr after virus infection. The activity of the ...

journal_title：Journal of virology

authors： Mahy BW,Hutchinson JE,Barry RD

更新日期：1970-06-01 00:00:00

abstract：:Recently it has been shown that kaposica, an immune evasion protein of Kaposi's sarcoma-associated herpesvirus, inactivates complement by acting on C3-convertases by accelerating their decay as well as by acting as a cofactor in factor I-mediated inactivation of their subunits C3b and C4b. Here, we have mapped the fun...

journal_title：Journal of virology

authors： Mullick J,Singh AK,Panse Y,Yadav V,Bernet J,Sahu A

更新日期：2005-05-01 00:00:00

abstract：:Herpes simplex virus (HSV) entry is dependent on the interaction of virion glycoprotein D (gD) with one of several cellular receptors. We previously showed that gD binds specifically to two structurally dissimilar receptors, HveA and HveC. We have continued our studies by using (i) a panel of baculovirus-produced gD m...

journal_title：Journal of virology

authors： Whitbeck JC,Muggeridge MI,Rux AH,Hou W,Krummenacher C,Lou H,van Geelen A,Eisenberg RJ,Cohen GH

更新日期：1999-12-01 00:00:00

abstract：:Human immunodeficiency virus type 1 infection of mononuclear phagocytes has been implicated in disease manifestations, but postentry viral replication events in these cells have not been well characterized. Productive infection of activated T cells is associated with cell proliferation and accumulation of full-length ...

journal_title：Journal of virology

authors： O'Brien WA,Namazi A,Kalhor H,Mao SH,Zack JA,Chen IS

更新日期：1994-02-01 00:00:00

abstract：:The poliovirus polyprotein is cotranslationally linked to myristic acid at its amino-terminal glycine residue. We investigated the role of myristoylation in the viral replication cycle by site-directed mutagenesis of this glycine codon. Synthetic full-length RNA transcripts carrying a Gly-to-Ala mutation (G4002A) gave...

journal_title：Journal of virology

authors： Kräusslich HG,Hölscher C,Reuer Q,Harber J,Wimmer E

更新日期：1990-05-01 00:00:00

abstract：:Synthesis of the proteins of rabies virus was studied in hamster cells infected with UV-irradiated virus. The UV target size of genes L, N, M1, and M2 was measured during primary transcription. Except for N, the target size of the remaining genes was considerably larger than that of their physical sizes. The data fit ...

journal_title：Journal of virology

authors： Flamand A,Delagneau JF

更新日期：1978-11-01 00:00:00

abstract：:The product of the v-myb oncogene of avian myeloblastosis virus is a nuclear protein with an associated DNA-binding activity. We demonstrated that the highly conserved amino-terminal domain of p48v-myb is required for its associated DNA-binding activity. This activity is not required for the nuclear localization of p4...

journal_title：Journal of virology

authors： Ibanez CE,Garcia A,Stober-Grässer U,Lipsick JS

更新日期：1988-11-01 00:00:00

abstract：:Kaposi's sarcoma-associated herpesvirus (KSHV) LANA is an 1,162-amino-acid protein that tethers terminal repeat (TR) DNA to mitotic chromosomes to mediate episome persistence in dividing cells. C-terminal LANA self-associates to bind TR DNA. LANA contains independent N- and C-terminal chromosome binding regions. N-ter...

journal_title：Journal of virology

authors： Kelley-Clarke B,De Leon-Vazquez E,Slain K,Barbera AJ,Kaye KM

更新日期：2009-05-01 00:00:00

abstract：:Vif counteracts the host restriction factor APOBEC3G (A3G) and other APOBEC3s by preventing the incorporation of A3G into progeny virions. We previously identified Vif mutants with a dominant-negative (D/N) phenotype that interfered with the function of wild-type Vif, inhibited the degradation of A3G, and reduced the ...

journal_title：Journal of virology

authors： Miyagi E,Welbourn S,Sukegawa S,Fabryova H,Kao S,Strebel K

更新日期：2020-03-17 00:00:00

abstract：:Mutations critical for the central nervous system (CNS) attenuation of the Sabin vaccine strains of poliovirus (PV) are located within the viral internal ribosome entry site (IRES). We examined the interaction of the IRESs of PV type 3 (PV3) and Sabin type 3 (Sabin3) with polypyrimidine tract-binding protein (PTB) and...

journal_title：Journal of virology

authors： Guest S,Pilipenko E,Sharma K,Chumakov K,Roos RP

更新日期：2004-10-01 00:00:00

abstract：UNLABELLED:The genus beta human papillomaviruses (beta HPVs) cause cutaneous lesions and are thought to be involved in the initiation of some nonmelanoma skin cancers (NMSCs), particularly in patients with the genetic disorder epidermodysplasia verruciformis (EV). We have previously reported that at least two of the ge...

journal_title：Journal of virology

authors： White EA,Walther J,Javanbakht H,Howley PM

更新日期：2014-08-01 00:00:00

abstract：:Strains of Sindbis virus differ in their virulence for mice of different ages; this variation is related in large part to variations in the amino acid compositions of E1 and E2, the surface glycoproteins. The comparative pathogenesis of Sindbis virus strains which are virulent or avirulent for newborn mice has not bee...

journal_title：Journal of virology

authors： Sherman LA,Griffin DE

更新日期：1990-05-01 00:00:00

abstract：:Cells expressing the low pH-triggered class II viral fusion protein E1 of Semliki Forest virus (SFV) were fused to target cells. Fusion was monitored by electrical capacitance and aqueous dye measurements. Electrical voltage-clamp measurements showed that SFV E1-induced cell-cell fusion occurred quickly after acidific...

journal_title：Journal of virology

authors： Markosyan RM,Kielian M,Cohen FS

更新日期：2007-10-01 00:00:00