Abstract:
:This paper describes Q beta noninfectious particles produced at 41 degrees C in a streptomycin-resistant Escherichia coli mutant which is temperature sensitive for suppression of a nonsense codon. The noninfectious particles resembled Q beta under the electron microscope and contained coat protein molecules in an amount similar to the amount in Q beta. However, they did not adsorb to F-piliated bacteria, and they were deficient in both minor capsid proteins of Q beta, maturation (IIa) and read-through (IIb). Proteins IIa and IIb were not produced in Qbeta-infected mutant cells at 41 degrees C. In addition, instead of the 30S RNA of Q beta, a shorter RNA, which sedimented mainly at 23 S, was found in the defective particles. The results are discussed in relation to the roles of proteins IIa and IIb of Q beta.
journal_name
J Viroljournal_title
Journal of virologyauthors
Engelberg-Kulka H,Israeli-Reches M,Dekel L,Friedmann Adoi
10.1128/JVI.29.3.1107-1117.1979subject
Has Abstractpub_date
1979-03-01 00:00:00pages
1107-17issue
3eissn
0022-538Xissn
1098-5514journal_volume
29pub_type
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journal_title:Journal of virology
pub_type: 杂志文章
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更新日期:1999-03-01 00:00:00