Differential factor binding at the promoter of early baculovirus gene PE38 during viral infection: GATA motif is recognized by an insect protein.

abstract：:Cell-to-cell movement of beet yellows closterovirus requires four structural proteins and a 6-kDa protein (p6) that is a conventional, nonstructural movement protein. Here we demonstrate that either virus infection or p6 overexpression results in association of p6 with the rough endoplasmic reticulum. The p6 protein p...

journal_title：Journal of virology

authors： Peremyslov VV,Pan YW,Dolja VV

更新日期：2004-04-01 00:00:00

abstract：:The simian virus 40 (SV40) core origin of replication consists of three functional domains. The sequence 5'-CACTACTTCTGGAATAG-3' with an imperfect inverted repeat (underlined), a palindrome with four 5'-GAGGC-3' pentanucleotide repeats, and a 17-base-pair A + T-rich segment. We have been able to assign primary functio...

journal_title：Journal of virology

authors： Parsons R,Anderson ME,Tegtmeyer P

更新日期：1990-02-01 00:00:00

abstract：:We present data that retroviral gene expression in early hematopoietic cells is subjected to transcriptional controls similar to those previously described for embryonic stem cells. Transient transfection experiments revealed that both the viral enhancer region in the U3 region of the long terminal repeat as well as a...

journal_title：Journal of virology

authors： Baum C,Hegewisch-Becker S,Eckert HG,Stocking C,Ostertag W

更新日期：1995-12-01 00:00:00

abstract：:The first step in the replication of the plus-stranded poliovirus RNA is the synthesis of a complementary minus strand. This process is initiated by the covalent attachment of UMP to the terminal protein VPg, yielding VPgpU and VPgpUpU. We have previously shown that these products can be made in vitro in a reaction th...

journal_title：Journal of virology

authors： Paul AV,Rieder E,Kim DW,van Boom JH,Wimmer E

更新日期：2000-11-01 00:00:00

abstract：:The internal structural proteins of retroviruses are proteolytically processed from the Gag polyprotein, which alone is able to assemble into virus-like particles when expressed in cells. All Gag proteins contain domains corresponding to the three structural proteins MA, CA, and NC. We have expressed the CA and NC dom...

journal_title：Journal of virology

authors： Campbell S,Vogt VM

更新日期：1995-10-01 00:00:00

abstract：:It has previously been shown that an electrophoretic variant form of the Rous sarcoma virus transforming protein, pp60v-src, exists in src-transformed cells. This variant, which was readily observed in vanadate-treated cells, was characterized as possessing extensive amino-terminal domain phosphotyrosine modification....

journal_title：Journal of virology

authors： Collett MS,Belzer SK

更新日期：1987-05-01 00:00:00

abstract：:Poliovirus mutants in neutralizing antigenic site 3B were constructed by replacing the glutamic acid residue at amino acid 74 of capsid protein VP2 (VP2074E), using site-specific mutagenesis methods. All viable mutants display small-plaque phenotypes. Characterization of these mutants indicates that capsid assembly is...

journal_title：Journal of virology

authors： Reynolds C,Birnby D,Chow M

更新日期：1992-03-01 00:00:00

abstract：:The phosphoprotein, P, of vesicular stomatitis virus (VSV) is a key subunit of the viral RNA-dependent RNA polymerase complex. The protein is phosphorylated at multiple sites in two different domains. We recently showed that specific serine and threonine residues within the amino-terminal acidic domain I of P protein ...

journal_title：Journal of virology

authors： Hwang LN,Englund N,Das T,Banerjee AK,Pattnaik AK

更新日期：1999-07-01 00:00:00

abstract：:Polyacrylamide gel electrophoretic analysis of purified preparations of human and calf diarrhea viruses indicated eight polypeptide components, or possibly nine in the case of the calf diarrhea virus. Thermal denaturation and analytical studies of the calf diarrhea virus genome showed it to consist of 11 double-strand...

journal_title：Journal of virology

authors： Rodger SM,Schnagl RD,Holmes IH

更新日期：1975-11-01 00:00:00

abstract：:Bovine leukemia virus (BLV) from either persistently infected bat cells or fetal lamb kidney cells induced rapid syncytium formation in F81 indicator cells. Distinct syncytia were seen within 2 h after inoculation of cells with highly concentrated (500-fold) cell-free BLV preparations and within 4 to 8 h when unconcen...

journal_title：Journal of virology

authors： Graves DC,Jones LV

更新日期：1981-06-01 00:00:00

abstract：:B cells secreting IgG antibodies, but not IgM, are thought to be solely responsible for vaccine-induced protection against rabies virus (RABV) infections in postexposure settings. In this report, we reinvestigated the potential for IgM to mediate protection in a mouse model of RABV vaccination. Immunocompetent mice im...

journal_title：Journal of virology

authors： Dorfmeier CL,Shen S,Tzvetkov EP,McGettigan JP

更新日期：2013-08-01 00:00:00

abstract：:Spring viremia of carp virus (SVCV) is a highly pathogenic Vesiculovirus in the common carp. The phosphoprotein (P protein) of SVCV is a multifunctional protein that acts as a polymerase cofactor and an antagonist of cellular interferon (IFN) response. Here, we report the 1.5-Å-resolution crystal structure of the P pr...

journal_title：Journal of virology

authors： Wang ZX,Liu SB,Guan H,Lu LF,Tu JG,Ouyang S,Zhang YA

更新日期：2020-07-16 00:00:00

abstract：:It is well established that host genetics, especially major histocompatibility complex (MHC) genes, are important determinants of human immunodeficiency virus disease progression. Studies with simian immunodeficiency virus (SIV)-infected Indian rhesus macaques have associated Mamu-B*17 with control of virus replicatio...

journal_title：Journal of virology

authors： Wojcechowskyj JA,Yant LJ,Wiseman RW,O'Connor SL,O'Connor DH

更新日期：2007-01-01 00:00:00

abstract：:The inhibition of protein synthesis by cycloheximide markedly stimulated adenovirus 2 early transcription (assayed in vivo and in vitro in nuclei) when the drug was added 3 h after infection of HeLa cells. The stimulation was not uniform but ranged from three- to eightfold for region 1A to 10- to 30-fold for region 2 ...

journal_title：Journal of virology

authors： Cross FR,Darnell JE Jr

更新日期：1983-02-01 00:00:00

abstract：:The purpose of this study was to determine whether a cell surface protein that can serve as coreceptor for herpes simplex virus type 1 (HSV-1) entry, herpesvirus entry mediator (previously designated HVEM but renamed HveA), also mediates HSV-1-induced cell-cell fusion. We found that transfection of DNA from KOS-804, a...

journal_title：Journal of virology

authors： Terry-Allison T,Montgomery RI,Whitbeck JC,Xu R,Cohen GH,Eisenberg RJ,Spear PG

更新日期：1998-07-01 00:00:00

abstract：:Murine gammaherpesvirus 68 (MHV68) infection of mice provides a tractable small-animal system for assessing viral requirements for establishment of and reactivation from latency. The M2 gene product has no homology to any known proteins but has been shown to play a role in both the establishment of MHV68 latency and r...

journal_title：Journal of virology

authors： DeZalia M,Speck SH

更新日期：2008-08-01 00:00:00

abstract：:Human cytomegalovirus (HCMV) exhibits a highly restricted host range. In this study, we sought to examine the relative significance of host and viral factors in activating early gene expression of the HCMV UL54 (DNA polymerase) promoter in murine cells. Appropriate activation of the UL54 promoter at early times is ess...

journal_title：Journal of virology

authors： García-Ramírez JJ,Ruchti F,Huang H,Simmen K,Angulo A,Ghazal P

更新日期：2001-01-01 00:00:00

abstract：:Exosomes are small vesicles secreted from cells that participate in intercellular communication events. Accumulating evidence demonstrates that host exosome pathways are hijacked by viruses and that virally modified exosomes contribute to virus spread and immune evasion. In the case of tumor viruses, recent findings s...

journal_title：Journal of virology

authors： Meckes DG Jr

更新日期：2015-05-01 00:00:00

abstract：:It is shown that the plasmid prophage P1 can be displaced by a superinfecting P1 phage in Escherichia coli recA(P1) lysogens. Six widely separated phage markers were used to distinguish between residual recombination and total substitution. It is further shown that superinfection of recA lysogens can lead to loss of b...

journal_title：Journal of virology

authors： Meurs E,D'Ari R

更新日期：1979-08-01 00:00:00

abstract：:cis-Acting elements in the viral genome RNA (vRNA) are essential for the translation, replication, and/or encapsidation of RNA viruses. In this study, a novel conserved cis-acting element was identified in the capsid-coding region of mosquito-borne flavivirus. The downstream of 5' cyclization sequence (5'CS) pseudokno...

journal_title：Journal of virology

authors： Liu ZY,Li XF,Jiang T,Deng YQ,Zhao H,Wang HJ,Ye Q,Zhu SY,Qiu Y,Zhou X,Qin ED,Qin CF

更新日期：2013-06-01 00:00:00

abstract：:The nucleotide sequence of the src gene and flanking regions of the Schmidt-Ruppin strain of Rous sarcoma virus (SR-A) was determined. The src region of SR-A was very homologous to that of recovered avian sarcoma virus (rASV1441), with only 17 differences among 1,578 nucleotides. The size of the predicted protein was ...

journal_title：Journal of virology

authors： Takeya T,Hanafusa H

更新日期：1982-10-01 00:00:00

abstract：:Influenza viral complementary RNA (cRNA), i.e., viral mRNA was radioactive when purified from the cytoplasmic fraction of cordycepin-treated canine kidney cells that were incubated with [methyl-3H]methionine during infection. Approximately 55 to 60% of the methyl-3H radioactivity was in internal N6-methyladenosine, a ...

journal_title：Journal of virology

authors： Krug RM,Morgan MA,Shatkin AJ

更新日期：1976-10-01 00:00:00

abstract：:When Epstein-Barr virus (EBV) negative cells (Raji) were treated with iododeoxyuridine, only the early antigen (EA) component was induced. There was no significant increase in EBV DNA and no virus particles were observed. Somatic-cell hybrids were prepared from the fusion of Raji and D98 cells (D98/Raji). When these c...

journal_title：Journal of virology

authors： Glaser R,Nonoyama M

更新日期：1974-07-01 00:00:00

abstract：:Herpes simplex virus type 1 (HSV-1) infection results in the disruption of ND10 (also called nuclear bodies, PODs, or PML-associated bodies), which are nuclear matrix domains of unknown function present in mammalian cells. After ND10 disruption, viral transcription and DNA replication occur in globular nuclear domains...

journal_title：Journal of virology

authors： Burkham J,Coen DM,Weller SK

更新日期：1998-12-01 00:00:00

abstract：:Type C RNA viruses initially isolated from a lymphosarcoma of a gibbon ape and from a fibrosarcoma of a woolly monkey are very closely related immunologically. However, recent studies have shown that these viruses are distinguishable in a radioimmunoassay for the 12,000-molecular-weight polypeptide (p12) of the woolly...

journal_title：Journal of virology

authors： Tronick SR,Stephenson JR,Aaronson SA,Kawakami TG

更新日期：1975-01-01 00:00:00

abstract：:In a study of the evolution and distribution of avian retroviruses, we found avian sarcoma and leukosis virus (ASLV) gag genes in 26 species of galliform birds from North America, Central America, eastern Europe, Asia, and Africa. Nineteen of the 26 host species from whom ASLVs were sequenced were not previously known...

journal_title：Journal of virology

authors： Dimcheff DE,Drovetski SV,Krishnan M,Mindell DP

更新日期：2000-05-01 00:00:00

abstract：:The initiation of RNA transcription by the virion-bound RNA transcriptase of vesicular stomatitis virus has been examined. Multiple initiation sequences have been observed, two of which have been characterized (pppApCpGp... and pppGpCp...) suggestive of a transcription process which can start at different sites along ...

journal_title：Journal of virology

authors： Roy P,Bishop DH

更新日期：1973-04-01 00:00:00

abstract：:In this study, we have identified an internal ribosome entry site (IRES) from the highly infectious herpesvirus Marek's disease virus (MDV). The IRES was mapped to the intercistronic region (ICR) of a bicistronic mRNA that we cloned from the MDV-transformed CD4(+) T-cell line MSB-1. The transcript is a member of a fam...

journal_title：Journal of virology

authors： Tahiri-Alaoui A,Smith LP,Baigent S,Kgosana L,Petherbridge LJ,Lambeth LS,James W,Nair V

更新日期：2009-06-01 00:00:00

abstract：:The interaction of simian virus 40 (SV40) T antigen (T-ag) with the viral origin has served as a model for studies of site-specific recognition of a eukaryotic replication origin and the mechanism of DNA unwinding. These studies have revealed that a motif termed the "beta-hairpin" is necessary for assembly of T-ag on ...

journal_title：Journal of virology

authors： Kumar A,Meinke G,Reese DK,Moine S,Phelan PJ,Fradet-Turcotte A,Archambault J,Bohm A,Bullock PA

更新日期：2007-05-01 00:00:00

abstract：:Macrophage adherence, an important regulatory signal, has the potential to affect human immunodeficiency virus (HIV) production either directly or by priming monocytes to respond to other activating signals. We have investigated the role of adherence as an activator of HIV-1 transcription and release. The effects of a...

journal_title：Journal of virology

authors： Shattock RJ,Friedland JS,Griffin GE

更新日期：1993-06-01 00:00:00