Fusion induced by a class II viral fusion protein, semliki forest virus E1, is dependent on the voltage of the target cell.

abstract：:A rat nephroma cell line was found to be a carrier culture of the Kilham rat virus. Infectious virus was demonstrable only by passage of culture materials into other host systems. ...

journal_title：Journal of virology

authors： Wozniak J,Hetrick F

更新日期：1969-09-01 00:00:00

abstract：:Although highly active antiretroviral therapy (HAART) for human immunodeficiency virus type 1 (HIV-1) infection can reduce levels of HIV-1 RNA in plasma to below the limit of detection, replication-competent forms of the virus persist in all infected individuals. One form of persistence involves a stable reservoir of ...

journal_title：Journal of virology

authors： Ruff CT,Ray SC,Kwon P,Zinn R,Pendleton A,Hutton N,Ashworth R,Gange S,Quinn TC,Siliciano RF,Persaud D

更新日期：2002-09-01 00:00:00

abstract：:The poliovirus (PV) genome was manipulated by replacing its 2A-encoding sequence with the corresponding sequence of coxsackie B4 virus (CBV4) or human rhinovirus type 2 (HRV2). In vitro translation of the resulting chimeric PV genomes revealed a normal cis-cleavage activity for both heterologous 2A(pro) proteinases in...

journal_title：Journal of virology

authors： Lu HH,Li X,Cuconati A,Wimmer E

更新日期：1995-12-01 00:00:00

abstract：:Dengue virus (DENV) infection causes serious clinical symptoms, including dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). Vascular permeability change is the main feature of the diseases, and the abnormal expression of proinflammatory cytokines is the important cause of vascular permeability change. Ho...

journal_title：Journal of virology

authors： Pan P,Zhang Q,Liu W,Wang W,Lao Z,Zhang W,Shen M,Wan P,Xiao F,Liu F,Zhang W,Tan Q,Liu X,Wu K,Liu Y,Li G,Wu J

更新日期：2019-10-15 00:00:00

abstract：:Kaposi's sarcoma-associated herpesvirus (KSHV) plays a significant role in the development of Kaposi's sarcoma, primary effusion lymphoma, and some forms of multicentric Castleman's disease. The KSHV open reading frame K9 encodes the viral interferon (IFN) factor 1 (vIRF1), which downregulates IFN- and IRF-mediated tr...

journal_title：Journal of virology

authors： Seo T,Lee D,Shim YS,Angell JE,Chidambaram NV,Kalvakolanu DV,Choe J

更新日期：2002-09-01 00:00:00

abstract：:The rarely identified influenza A viruses of the H15 hemagglutinin subtype have been isolated exclusively in Australia. Here we report the isolation of an H15N4 influenza A virus (A/teal/Chany/7119/2008) in Western Siberia, Russia. Phylogenetic analysis demonstrated that the internal genes of the A/teal/Chany/7119/200...

journal_title：Journal of virology

authors： Sivay MV,Baranovich T,Marchenko VY,Sharshov KA,Govorkova EA,Shestopalov AM,Webby RJ

更新日期：2013-03-01 00:00:00

abstract：:Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic agent of adult T-cell leukemia/lymphoma and is associated with a variety of immunoregulatory disorders. HTLV-1 has been shown to bind to and infect a variety of hematopoietic and nonhematopoietic cells. However, both in vivo and in vitro, the provirus is mos...

journal_title：Journal of virology

authors： Newbound GC,Andrews JM,O'Rourke JP,Brady JN,Lairmore MD

更新日期：1996-04-01 00:00:00

abstract：:Purified Kunjin virus was disrupted with sodium dodecyl sulfate, urea, and mercaptoethanol or acetic acid. Electrophoresis on 7.5% polyacrylamide gel separated four proteins of high (120,000), intermediate (65,000) and low (18,000 and 13,000) molecular weights. A "core" particle was obtained by degradation of the viri...

journal_title：Journal of virology

authors： Westaway EG,Reedman BM

更新日期：1969-11-01 00:00:00

abstract：:We prepared retrovirus packaging cell lines containing gag-pol genes from spleen necrosis virus (expressed from a cytomegalovirus promoter and the simian virus 40 (SV40) polyadenylation sequences) and, on a separate vector, either the env gene from spleen necrosis virus (expressed from the Rous sarcoma virus promoter ...

journal_title：Journal of virology

authors： Dougherty JP,Wisniewski R,Yang SL,Rhode BW,Temin HM

更新日期：1989-07-01 00:00:00

abstract：:Rice yellow mottle virus is classified in five major serotypes; the molecular diversity of the coat protein (CP) is well established, but the amino acids involved in the recognition by discriminant monoclonal antibodies (MAbs) remain unknown. Reconstruction of a phylogenetic tree and sequence alignment of the CP gene ...

journal_title：Journal of virology

authors： Hébrard E,Pinel-Galzi A,Catherinot V,Labesse G,Brugidou C,Fargette D

更新日期：2005-04-01 00:00:00

abstract：:Evidence is presented that the herpes simplex virus type 2 glycoprotein previously designated gF is antigenically related to herpes simplex virus type 1 gC (gC-1). An antiserum prepared against type 1 virion envelope proteins immunoprecipitated gF of type 2 (gF-2), and competition experiments revealed that the anti-gC...

journal_title：Journal of virology

authors： Zezulak KM,Spear PG

更新日期：1983-09-01 00:00:00

abstract：:The nature of the lesions involved in producing the fusiform phenotype of three mutants (WO101, WO201, and tsST529) of the Schmidt-Ruppin A strain of Rous sarcoma virus (RSV) was determined by molecular cloning and DNA sequencing. WO101 and WO201 contained an in-frame deletion of the v-src region coding for amino acid...

journal_title：Journal of virology

authors： Anderson SK,Fujita DJ

更新日期：1987-06-01 00:00:00

abstract：UNLABELLED:Human cytomegalovirus (HCMV) is a major cause of morbidity and mortality in transplant patients and is the leading viral cause of birth defects after congenital infection. HCMV infection relies on the recognition of cell-specific receptors by one of the viral envelope glycoprotein complexes. Either the gH/gL...

journal_title：Journal of virology

authors： Caló S,Cortese M,Ciferri C,Bruno L,Gerrein R,Benucci B,Monda G,Gentile M,Kessler T,Uematsu Y,Maione D,Lilja AE,Carfí A,Merola M

更新日期：2016-04-29 00:00:00

abstract：:Infection of newborn Lewis rats with Borna disease virus (neonatal Borna disease [NBD]) results in cerebellar damage without the cellular inflammation associated with infections in later life. Purkinje cell (PC) damage has been reported for several models of early-life viral infection, including NBD; however, the time...

journal_title：Journal of virology

authors： Williams BL,Yaddanapudi K,Hornig M,Lipkin WI

更新日期：2007-03-01 00:00:00

abstract：:Infection of cells with herpes simplex virus type 1 (HSV-1) induces high levels of deoxypyrimidine triphosphatase. The majority of the enzyme activity is found in infected cell nuclei. A similar activity is induced by HSV type 2 (HSV-2) which, in contrast to the HSV-1 enzyme, fractionates to more than 99% in the solub...

journal_title：Journal of virology

authors： Wohlrab F,Garrett BK,Francke B

更新日期：1982-09-01 00:00:00

abstract：:We have previously identified 11 epitopes located in two topologically nonoverlapping antigenic sites (A and B) and a third bridging site (C) on the human type 3 parainfluenza virus (PIV3) hemagglutinin-neuraminidase (HN) glycoprotein by using monoclonal antibodies (MAbs) which inhibit hemagglutination and virus infec...

journal_title：Journal of virology

authors： Coelingh KJ,Winter CC,Murphy BR,Rice JM,Kimball PC,Olmsted RA,Collins PL

更新日期：1986-10-01 00:00:00

abstract：UNLABELLED:The HIV-1 envelope protein (Env) is heavily glycosylated, with approximately 50% of the Env molecular mass being contributed by N-glycans. HIV-1 Env N-glycans shield the protein backbone and have been shown to play key roles in determining Env structure, surface exposure, and, consequently, antigenicity, inf...

journal_title：Journal of virology

authors： Shen R,Raska M,Bimczok D,Novak J,Smith PD

更新日期：2014-12-01 00:00:00

abstract：:The majority of people infected with hepatitis C virus (HCV) fail to generate or maintain a T-cell response effective for viral clearance. Evidence from murine chronic viral infections shows that expression of the coinhibitory molecule PD-1 predicts CD8+ antiviral T-cell exhaustion and may contribute to inadequate pat...

journal_title：Journal of virology

authors： Radziewicz H,Ibegbu CC,Fernandez ML,Workowski KA,Obideen K,Wehbi M,Hanson HL,Steinberg JP,Masopust D,Wherry EJ,Altman JD,Rouse BT,Freeman GJ,Ahmed R,Grakoui A

更新日期：2007-03-01 00:00:00

abstract：UNLABELLED:Reactivation of human cytomegalovirus (HCMV) is a significant cause of disease and death in immunocompromised patients, underscoring the need to understand how latency is controlled. Here we demonstrate that HCMV has evolved to utilize cellular microRNAs (miRNAs) in cells that promote latency to regulate exp...

journal_title：Journal of virology

authors： O'Connor CM,Vanicek J,Murphy EA

更新日期：2014-05-01 00:00:00

abstract：UNLABELLED:Nonhuman primates (NHPs) are a historically important source of zoonotic viruses and are a gold-standard model for research on many human pathogens. However, with the exception of simian immunodeficiency virus (SIV) (family Retroviridae), the blood-borne viruses harbored by these animals in the wild remain i...

journal_title：Journal of virology

authors： Bailey AL,Lauck M,Ghai RR,Nelson CW,Heimbruch K,Hughes AL,Goldberg TL,Kuhn JH,Jasinska AJ,Freimer NB,Apetrei C,O'Connor DH

更新日期：2016-07-11 00:00:00

abstract：:The small envelope protein (E) plays a role of central importance in the assembly of coronaviruses. This was initially established by studies demonstrating that cellular expression of only E protein and the membrane protein (M) was necessary and sufficient for the generation and release of virus-like particles. To inv...

journal_title：Journal of virology

authors： Kuo L,Hurst KR,Masters PS

更新日期：2007-03-01 00:00:00

abstract：:We constructed a DNA fragment map of low-passage Towne strain cytomegalovirus by analyzing cross-blot hybridization and hybridizations of isolated recombinant clones. The abundant late transcripts were located on this map by hybridization of labeled total RNA of virus-infected cells to blotted DNA fragments. The most ...

journal_title：Journal of virology

authors： Davis MG,Mar EC,Wu YM,Huang ES

更新日期：1984-10-01 00:00:00

abstract：:We have cloned several prototypic members of the family of human endogenous retroviruslike elements having a histidine tRNA primer-binding site (RTVL-H) and have determined the nucleotide sequence of one of these clones (RTVL-H2). The RTVL-H2 sequence is 5,813 nucleotides long, with long terminal repeats of 450 nucleo...

journal_title：Journal of virology

authors： Mager DL,Freeman JD

更新日期：1987-12-01 00:00:00

abstract：:Nidoviruses (arteriviruses, coronaviruses, and roniviruses) are a phylogenetically compact but diverse group of positive-strand RNA viruses that includes important human and animal pathogens. Nidovirus RNA synthesis is mediated by a cytoplasmic membrane-associated replication/transcription complex that includes up to ...

journal_title：Journal of virology

authors： Nedialkova DD,Ulferts R,van den Born E,Lauber C,Gorbalenya AE,Ziebuhr J,Snijder EJ

更新日期：2009-06-01 00:00:00

abstract：:The transcriptional activities of the four hepatitis B virus promoters were compared in three differentiated hepatoma cell lines, HepG2, Hep3B, and PLC/PRF/5; a dedifferentiated subline of HepG2, HepG2.1; a human cervical carcinoma cell line, HeLa S3; and a mouse fibroblast cell line, NIH 3T3. The plasmid constructs, ...

journal_title：Journal of virology

authors： Raney AK,Milich DR,Easton AJ,McLachlan A

更新日期：1990-05-01 00:00:00

abstract：UNLABELLED:Mumps virus (MuV), a paramyxovirus containing a negative-sense nonsegmented RNA genome, is a human pathogen that causes an acute infection with symptoms ranging from parotitis to mild meningitis and severe encephalitis. Vaccination against mumps virus has been effective in reducing mumps cases. However, rece...

journal_title：Journal of virology

authors： Pickar A,Xu P,Elson A,Li Z,Zengel J,He B

更新日期：2014-04-01 00:00:00

abstract：:A fragment of chicken DNA containing the left long terminal repeat of endogenous retrovirus ev-2 and flanking cellular sequences has been molecularly cloned and analyzed. Comparison with sequence data from the analogous regions of ev-1 and Rous-associated virus-0 viral DNA reveals similarities among flanking regions o...

journal_title：Journal of virology

authors： Scholl DR,Kahn S,Malavarca R,Astrin S,Skalka AM

更新日期：1983-02-01 00:00:00

abstract：:Monoclonal antibodies (MAbs) were raised against human immunodeficiency virus type 1 gp120. One MAb, P4/D10, was found to mediate highly efficient antibody-dependent cellular cytotoxicity and virus neutralization. The reactivity was located to a major neutralizing region (amino acids 304 to 323) on gp120. Five other M...

journal_title：Journal of virology

authors： Broliden PA,Ljunggren K,Hinkula J,Norrby E,Akerblom L,Wahren B

更新日期：1990-02-01 00:00:00

abstract：:Influenza A virus infection can arrest autophagy, as evidenced by autophagosome accumulation in infected cells. Here, we report that this autophagosome accumulation can be inhibited by amantadine, an antiviral proton channel inhibitor, in amantadine-sensitive virus infected cells or cells expressing influenza A virus ...

journal_title：Journal of virology

authors： Ren Y,Li C,Feng L,Pan W,Li L,Wang Q,Li J,Li N,Han L,Zheng X,Niu X,Sun C,Chen L

更新日期：2015-10-14 00:00:00

abstract：:The limited efficiency of in vivo gene transfer by replication-deficient retroviral vectors remains an obstacle to achieving effective gene therapy for solid tumors. One approach to circumvent this problem is the use of replication-competent retroviral vectors. However, the application of such vectors is at a comparat...

journal_title：Journal of virology

authors： Paar M,Schwab S,Rosenfellner D,Salmons B,Günzburg WH,Renner M,Portsmouth D

更新日期：2007-07-01 00:00:00