Vesicular stomatitis virus glycoprotein does not determine the site of virus release in polarized epithelial cells.

abstract：:Poliovirus (PV) is easily transferred to humans orally; however, no rodent model for oral infections has been developed because of the alimentary tract's low sensitivity to the virus. Here we showed that PV is inactivated by the low pH of the gastric contents in mice. The addition of 3% NaHCO3 to the viral inoculum in...

journal_title：Journal of virology

authors： Ohka S,Igarashi H,Nagata N,Sakai M,Koike S,Nochi T,Kiyono H,Nomoto A

更新日期：2007-08-01 00:00:00

abstract：:The arterivirus equine arteritis virus nonstructural protein 10 (nsp10) has previously been predicted to contain a Zn finger structure linked to a superfamily 1 (SF1) helicase domain. A recombinant form of nsp10, MBP-nsp10, was produced in Escherichia coli as a fusion protein with the maltose-binding protein. The prot...

journal_title：Journal of virology

authors： Seybert A,van Dinten LC,Snijder EJ,Ziebuhr J

更新日期：2000-10-01 00:00:00

abstract：:Several domains of CD4 have been suggested to play a critical role in events that follow its binding to the human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein (gp120-gp41). It has been reported previously that cells expressing a chimeric molecule consisting of the first 177 residues of human CD4 attache...

journal_title：Journal of virology

authors： Golding H,Blumenthal R,Manischewitz J,Littman DR,Dimitrov DS

更新日期：1993-11-01 00:00:00

abstract：:The cytolytic T-lymphocyte (CTL) response to respiratory infection with equine herpesvirus 1 (EHV-1) in CBA (H-2(k)) mice was investigated. Intranasal (i.n.) inoculation of mice with the attenuated EHV-1 strain KyA resulted in the generation of a primary virus-specific CTL response in the draining mediastinal lymph no...

journal_title：Journal of virology

authors： Smith PM,Zhang Y,Jennings SR,O'Callaghan DJ

更新日期：1998-07-01 00:00:00

abstract：UNLABELLED:Arthritogenic alphaviruses such as Ross River virus (RRV) and chikungunya virus (CHIKV) cause large-scale epidemics of severe musculoskeletal disease and have been progressively expanding their global distribution. Since its introduction in July 2014, CHIKV now circulates in the United States. The hallmark o...

journal_title：Journal of virology

authors： Herrero LJ,Foo SS,Sheng KC,Chen W,Forwood MR,Bucala R,Mahalingam S

更新日期：2015-08-01 00:00:00

abstract：:Poliovirus has been studied as a live recombinant vaccine vector because of its attractive characteristics. The genetic instability, however, has hampered recombinant polioviruses (PVs) from being developed as an appropriate vaccine. A variety of different foreign inserts were cloned directly into our poliovirus Sabin...

journal_title：Journal of virology

authors： Lee SG,Kim DY,Hyun BH,Bae YS

更新日期：2002-02-01 00:00:00

abstract：:Infections of fungi by mycoviruses are often symptomless but sometimes also fatal, as they perturb sporulation, growth, and, if applicable, virulence of the fungal host. Hypovirulence-inducing mycoviruses, therefore, represent a powerful means to defeat fungal epidemics on crop plants. Infection with Fusarium graminea...

journal_title：Journal of virology

authors： Bormann J,Heinze C,Blum C,Mentges M,Brockmann A,Alder A,Landt SK,Josephson B,Indenbirken D,Spohn M,Plitzko B,Loesgen S,Freitag M,Schäfer W

更新日期：2018-08-16 00:00:00

abstract：:Selecting human immunodeficiency virus (HIV) sequences for inclusion within vaccines has been a difficult problem, as circulating HIV strains evolve relentlessly and become increasingly divergent over time. We report an assessment of this divergence from three perspectives: (i) across different hosts as a function of ...

journal_title：Journal of virology

authors： Herbeck JT,Nickle DC,Learn GH,Gottlieb GS,Curlin ME,Heath L,Mullins JI

更新日期：2006-02-01 00:00:00

abstract：:Respiratory syncytial (RS) virus infects the epithelium of the respiratory tract. We examined the replication and maturation of RS virus in two polarized epithelial cell lines, Vero C1008 and MDCK. Electron microscopy of RS virus-infected Vero C1008 cells revealed the presence of pleomorphic viral particles budding ex...

journal_title：Journal of virology

authors： Roberts SR,Compans RW,Wertz GW

更新日期：1995-04-01 00:00:00

abstract：:Prior studies demonstrated that immunization of macaques with simian immunodeficiency virus (SIV) Gag-Pol and Env recombinants of the attenuated poxvirus modified vaccinia virus Ankara (MVA) provided protection from high levels of viremia and AIDS following challenge with a pathogenic strain of SIV (V. M. Hirsch et al...

journal_title：Journal of virology

authors： Ourmanov I,Brown CR,Moss B,Carroll M,Wyatt L,Pletneva L,Goldstein S,Venzon D,Hirsch VM

更新日期：2000-03-01 00:00:00

abstract：:A retrovirus vector has been developed that selects for instances in which the provirus integrates in close proximity to cellular promoters. Coding sequences for a selectable marker (histidinol dehydrogenase) were inserted into the 3' long terminal repeat (LTR) of an enhancerless Molony murine leukemia virus. Although...

journal_title：Journal of virology

authors： von Melchner H,Ruley HE

更新日期：1989-08-01 00:00:00

abstract：:Bacterial lipopolysaccharide (LPS) induces interferon (IFN) secretion and an antiviral state in murine peritoneal macrophages (PM). These cells secrete predominantly IFN-beta, as shown by neutralization assays with monoclonal antibodies. Secretion of IFN-beta is also induced in PM by IFN-gamma. LPS and IFN-gamma syner...

journal_title：Journal of virology

authors： Gessani S,Belardelli F,Pecorelli A,Puddu P,Baglioni C

更新日期：1989-06-01 00:00:00

abstract：:Here, we report a novel porcine circovirus type 2a (PCV2a) strain with 11 nucleotides (nt) inserted in the origin of genome replication (Ori). This is the first report of a PCV2a strain with nucleotide insertion in Ori. Our study will help further epidemiological studies and extend our knowledge of evolutionary charac...

journal_title：Journal of virology

authors： Cai L,Han X,Hu D,Li X,Wang B,Ni J,Zhou Z,Yu X,Zhai X,Tian K

更新日期：2012-06-01 00:00:00

abstract：:Infection of cells with poliovirus induces a massive intracellular membrane reorganization to form vesicle-like structures where viral RNA replication occurs. The mechanism of membrane remodeling remains unknown, although some observations have implicated components of the cellular secretory and/or autophagy pathways....

journal_title：Journal of virology

authors： Belov GA,Altan-Bonnet N,Kovtunovych G,Jackson CL,Lippincott-Schwartz J,Ehrenfeld E

更新日期：2007-01-01 00:00:00

abstract：:Antibodies present in two peritoneal exudates of rats bearing abdominal tumors induced by UR2-transformed rat cells were characterized. The ability to immunoprecipitate p68gag-ros and to inhibit the protein and phospholipid kinase activities of this protein was investigated. One of the exudates specifically inhibited ...

journal_title：Journal of virology

authors： Balduzzi PC,Chovav M,Christensen JR,Macara IG

更新日期：1986-11-01 00:00:00

abstract：:Temperature-sensitive (ts) mutants were isolated from the baculovirus Autographa californica (alfalfa looper) MNPV, grown in Spodoptera frugiperda (fall armyworm) cells in the presence of N-methyl-N'-nitro-N-nitrosoguanidine. Of 567 plaque isolates screened, 27 were temperature sensitive (ts), representing a mutation ...

journal_title：Journal of virology

authors： Brown M,Crawford AM,Faulkner P

更新日期：1979-07-01 00:00:00

abstract：:The pandemic threat posed by emerging zoonotic influenza A viruses necessitates development of antiviral agents effective against various antigenic subtypes. Human monoclonal antibody (hMAb) targeting the hemagglutinin (HA) stalk offers a promising approach to control influenza virus infections. Here, we investigated ...

journal_title：Journal of virology

authors： Marjuki H,Mishin VP,Chai N,Tan MW,Newton EM,Tegeris J,Erlandson K,Willis M,Jones J,Davis T,Stevens J,Gubareva LV

更新日期：2016-11-14 00:00:00

abstract：:Defective-interfering (DI) particles are helper-dependent deletion mutants which interfere specifically with the replication of the homologous standard virus. Serial passaging of alphaviruses in cultured cells leads to the accumulation of DI particles whose genomic RNAs are heterogeneous in size and sequence compositi...

journal_title：Journal of virology

authors： Monroe SS,Schlesinger S

更新日期：1984-03-01 00:00:00

abstract：:We investigated the susceptibilities of Syrian golden hamsters to transmissible spongiform encephalopathy agents from cattle. We report efficient transmission of the L-type atypical bovine spongiform encephalopathy (BSE) agent into hamsters. Importantly, hamsters were also susceptible to the transmissible mink encepha...

journal_title：Journal of virology

authors： Nicot S,Baron T

更新日期：2011-02-01 00:00:00

abstract：:Human adenoviruses typically cause mild infections in the upper or lower respiratory tract, gastrointestinal tract, or ocular epithelium. However, adenoviruses may be life-threatening in patients with impaired immunity and some serotypes cause epidemic outbreaks. Attachment to host cell receptors activates cell signal...

journal_title：Journal of virology

authors： Zeng X,Carlin CR

更新日期：2013-02-01 00:00:00

abstract：:Type C RNA virus(es) was readily released from primary lymphosarcoma cell cultures of WH/J rabbits after induction with halogenated pyrimidines. The virus contained an RNA-directed DNA polymerase and the p30 structural protein. The rabbit virus RNA-directed DNA polymerase and p30 protein shared antigenic homologies wi...

journal_title：Journal of virology

authors： Bedigian HG,Fox RR,Meier H

更新日期：1978-08-01 00:00:00

abstract：:Heat shock protein 70 (Hsp70) is incorporated within the membrane of primate lentiviral virions. Here we demonstrate that Hsp70 is also incorporated into oncoretroviral virions and that it remains associated with membrane-stripped human immunodeficiency virus type 1 (HIV-1) virion cores. To determine if Hsp70 promotes...

journal_title：Journal of virology

authors： Gurer C,Höglund A,Höglund S,Luban J

更新日期：2005-05-01 00:00:00

abstract：:Highly pathogenic influenza A viruses (IAV) from avian hosts were first reported to directly infect humans 20 years ago. However, such infections are rare events, and our understanding of factors promoting or restricting zoonotic transmission is still limited. One accessory protein of IAV, PB1-F2, was associated with ...

journal_title：Journal of virology

authors： Mazel-Sanchez B,Boal-Carvalho I,Silva F,Dijkman R,Schmolke M

更新日期：2018-05-14 00:00:00

abstract：:JC virus (JCV), along with other members of the polyomavirus family, encodes a class of highly conserved proteins, T antigens, that are capable of inducing aneuploidy in cultured cells. We have previously isolated T-antigen DNA variants of JCV from both colon cancer tissues and the corresponding nonneoplastic gastroin...

journal_title：Journal of virology

authors： Ricciardiello L,Chang DK,Laghi L,Goel A,Chang CL,Boland CR

更新日期：2001-02-01 00:00:00

abstract：:The Epstein-Barr virus (EBV) BamHI-A rightward transcripts (BARTs) are expressed in all EBV-associated tumors as well as in latently infected B cells in vivo and cultured B-cell lines. One of the BART family transcripts contains an open reading frame, RPMS1, that encodes a nuclear protein termed RPMS. Reverse transcri...

journal_title：Journal of virology

authors： Zhang J,Chen H,Weinmaster G,Hayward SD

更新日期：2001-03-01 00:00:00

abstract：:Feline panleukopenia virus (FPV) and its host range variant, canine parvovirus (CPV), can bind the feline transferrin receptor (TfR), while only CPV binds to the canine TfR. Introducing two CPV-specific changes into FPV (at VP2 residues 93 and 323) endowed that virus with the canine TfR binding property and allowed ca...

journal_title：Journal of virology

authors： Hueffer K,Govindasamy L,Agbandje-McKenna M,Parrish CR

更新日期：2003-09-01 00:00:00

abstract：:In vitro replication of coxsackievirus B3 (CVB3) in cells of the immune system derived from uninfected adolescent A/J and C57BL/6J mice and replication of CVB3 in and association with immune cells from spleens of infected animals in vivo were assessed. Nonstimulated or mitogen-stimulated spleen cells were minimally pe...

journal_title：Journal of virology

authors： Anderson DR,Wilson JE,Carthy CM,Yang D,Kandolf R,McManus BM

更新日期：1996-07-01 00:00:00

abstract：UNLABELLED:Microtubule transport of circovirus from the periphery of the cell to the nucleus is essential for viral replication in early infection. How the microtubule is recruited to the viral cargo remains unclear. In this study, we observed that circovirus trafficking is dependent on microtubule polymerization and t...

journal_title：Journal of virology

authors： Cao J,Lin C,Wang H,Wang L,Zhou N,Jin Y,Liao M,Zhou J

更新日期：2015-03-01 00:00:00

abstract：:The major envelope glycoproteins gp120 and gp41 of human immunodeficiency virus type 1, the causative agent for human AIDS, contain numerous N-linked oligosaccharides. We report here our discovery that N-acetylglucosamine residues within the complex-type N-linked oligosaccharides of both gp120 and its precursor, gp160...

journal_title：Journal of virology

authors： Shilatifard A,Merkle RK,Helland DE,Welles JL,Haseltine WA,Cummings RD

更新日期：1993-02-01 00:00:00

abstract：:Retrovirus particles each contain two copies of the viral genome in the form of a noncovalently linked RNA dimer. Earlier studies have mapped a cis-acting region near the 5' end of the human immunodeficiency virus type 1 (HIV-1) genome, termed the psi locus, which appears essential for initiation of genomic dimerizati...

journal_title：Journal of virology

authors： Clever JL,Parslow TG

更新日期：1997-05-01 00:00:00