Abstract:
OBJECTIVE:To investigate the treatment efficacy of adefovir dipivoxil combined with a corticosteroid on hepatitis B virus-associated glomerulonephritis (HBV-GN). METHODS:A total of 38 patients with nephrotic syndrome induced by HBV-GN were treated for 36 weeks between 2010 and 2012. RESULTS:The efficacy analysis showed that 11 patients achieved complete remission and 17 patients achieved partial remission, and the effective remission rate was 73.7%. In addition, 10 patients achieved no remission. CONCLUSIONS:Adefovir dipivoxil combined with corticosteroids has a certain efficacy on the HBV-GN and displays few adverse reactions. A large sample, randomized double-blind controlled study and long-term follow-up are needed to verify the efficacy of adefovir dipivoxil combined with corticosteroids.
journal_name
Ren Failjournal_title
Renal failureauthors
Li H,Yuan X,Qiu L,Zhou Q,Xiao Pdoi
10.3109/0886022X.2014.952745subject
Has Abstractpub_date
2014-10-01 00:00:00pages
1404-6issue
9eissn
0886-022Xissn
1525-6049journal_volume
36pub_type
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