Effects of nitric oxide synthesis inhibition on FK506-induced nephrotoxicity in rats.

abstract：BACKGROUND:Chronic kidney disease (CKD) is associated with markedly increased cardiovascular (CV) risk. This increase is not fully explained by traditional CV risk factors but may in part be mediated by nontraditional risk factors, such as inadequate vitamin D (vit D) levels and insulin resistance (IR). Although IR is ...

journal_title：Renal failure

authors： Lai S,Coppola B,Dimko M,Galani A,Innico G,Frassetti N,Mariotti A

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:The kidney is a major site for the inactivation, degradation, and clearance of a variety of peptide hormones. It has been shown that the uremia increases or decreases gastrointestinal system (GIS) hormones. Moreover, studies investigating the serum GIS hormones levels in chronic renal failure (CRF) were cond...

journal_title：Renal failure

authors： Borazan A,Cavdar Z,Saglam F

更新日期：2007-01-01 00:00:00

abstract：:The renal functional reserve (RFR) is the ability of the kidneys to increase renal plasma flow and glomerular filtration rate (GFR) in response to protein intake. It is a measure of functional and anatomic integrity of nephrons. It is not known what relation between RFR and kidney Doppler parameters. We aimed to study...

journal_title：Renal failure

authors： Gaipov A,Solak Y,Zhampeissov N,Dzholdasbekova A,Popova N,Molnar MZ,Tuganbekova S,Iskandirova E

更新日期：2016-10-01 00:00:00

abstract：:Ciprofloxacin has been associated with several side effects including interstitial nephritis and hemolytic anemia. The combination of both side effects is extremely rare. In this report, we describe a case of ciprofloxacin-induced interstitial nephritis and autoimmune hemolytic anemia. Hemolytic anemia improved after ...

journal_title：Renal failure

authors： Lim S,Alam MG

更新日期：2003-07-01 00:00:00

abstract：:The case records of 75 patients who had systemic lupus erythematosus (SLE) and renal involvement on renal histology were reviewed. There were 70 females and 5 males, with a ratio of 14:1. The majority of the patients were in their second and third decades of life. SLE nephritis was distinctly uncommon in patients belo...

journal_title：Renal failure

authors： Williams W,Shah D

更新日期：1990-01-01 00:00:00

abstract：:The present study was carried out to describe epidemiology and clinical pattern of acute renal failure caused by leptospirosis in Uruguay. For these purposes, all literature published in Uruguay was reviewed. Three studies were analyzed: 2 series of patients and 1 case report that summarize 26 cases. The incidence of ...

journal_title：Renal failure

authors： Lombardi R

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:Interleukin 17 (IL-17) plays an important role in the pathogenesis of autoimmune diseases and might be associated with IgA nephropathy (IgAN). This study aimed to investigate the effect of IL-17 on autoimmune pathogenesis in IgA nephropathy. METHODS:DAKIKI cells were cultured and stimulated with IL-17 to pe...

journal_title：Renal failure

authors： Lin JR,Wen J,Zhang H,Wang L,Gou FF,Yang M,Fan JM

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Arteriovenous fistulae (AVFs) may remain patent after kidney transplantation (KTx), contributing to maladaptive cardiac remodeling. The flow in AVFs is associated with the diameter of its vessels and thus with the AVF location. The main objective of this study is to assess the influence of AVF location and i...

journal_title：Renal failure

authors： Letachowicz K,Bardowska K,Królicki T,Kamińska D,Banasik M,Zajdel K,Mazanowska O,Madziarska K,Janczak D,Krajewska M

更新日期：2021-12-01 00:00:00

abstract：BACKGROUND:The thrombotic thrombocytopenic purpura (TTP) is a rare disorder with a high mortality rate if untreated or delayed therapy. Whether immediate diagnosis and promptly treated with plasma exchange can change the grave prognosis? METHOD:Retrospective analysis was performed on clinical characteristics and treat...

journal_title：Renal failure

authors： Yang CW,Chen YC,Dunn P,Chang MY,Fang JT,Huang CC

更新日期：2003-01-01 00:00:00

abstract：:Microalbumin is a basic biochemical test that is widely used at present. Owing to the concept of point-of-care testing (POCT), there are tools available for analysis of microalbumin. Here, the author performs a brief assessment on weight-turnaround time properties for available POCT for determination of microalbumin i...

journal_title：Renal failure

authors： Wiwanitkit V

更新日期：2010-05-01 00:00:00

abstract：:Compared to prior studies which frequently pinpoint the impairment of one parameter or function, this paper reports for the first time an extensive characterization of the toxic effects of gentamicin in a single model of primary cultured rabbit proximal tubule cells developed without insulin and glucose. Biochemical, ...

journal_title：Renal failure

authors： Monteil C,Leclere C,Fillastre JP,Morin JP

更新日期：1993-01-01 00:00:00

abstract：:Investigations were done in 10- and 55-day-old Wistar rats. Glutathione (GSH) level in kidney was decreased by 8 mmol buthionine sulfoximine (BSO)/100 g BW. There was no effect on the renal function and nephrotoxicity of cisplatin (0.6 mg CP/100 g BW) in adult rats. In young rats BSO treatment was followed by nephroto...

journal_title：Renal failure

authors： Appenroth D,Winnefeld K

更新日期：1993-01-01 00:00:00

abstract：:Idiopathic nephrotic syndrome (NS) associated with focal segmental glomerulosclerosis (FSGS) and severe renal function impairment is usually refractory to the conventional treatment and progresses to end-stage renal disease. Herein, we reported 10 patients with NS-FSGS who had initially had CCr 34 +/- 12 mL/min/1.73 m...

journal_title：Renal failure

authors： Futrakul N,Siriviriyakul P,Deekajorndej T,Futrakul P

更新日期：2004-05-01 00:00:00

abstract：:Many Chinese like to drink alcohol soaked with creatures for promoting health. This study reports a 49-year-old male who presented with multiple focal neuropathies of the upper limbs, coagulopathy, erythematous swelling of the bilateral upper extremities and trunk with bullous skin lesions, and rhabdomyolysis associat...

journal_title：Renal failure

authors： Wang IK,Hsu SP,Chi CC,Lee KF,Lin PY,Chang HW,Chuang FR

更新日期：2004-01-01 00:00:00

abstract：:Non-Shiga-like toxin-producing Escherichia coli (STEC) or atypical hemolytic uremic syndrome (aHUS) is observed in 5-10% of all hemolytic uremic syndrome (HUS) cases, and usually develops secondary to infections, malignancies, drugs, transplantation, pregnancy, and autoimmune disease. However, there has been no report...

journal_title：Renal failure

authors： Lee JW,Won NH,Cho E,Kim MG,Jo SK,Cho WY,Kim HK

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Patients with chronic kidney disease (CKD) often have CD4+ regulatory T cells (Tregs) dysfunction and chronic inflammation. We aim to investigate the effect, function, and related mechanism of low-dose IL-2 on CD4+ regulatory T cells expansion in vitro from patients with CKD. METHODS:A total of 148 newly di...

journal_title：Renal failure

authors： Li Y,Liu X,Wang W,Wang S,Zhang J,Jiang S,Wang Y,Li L,Li J,Zhang Y,Huang H

更新日期：2018-11-01 00:00:00

abstract：:Cardiovascular problems are a major cause of morbidity and mortality in patients with autosomal dominant polycystic kidney disease (ADPKD). Endothelial dysfunction (ED), which is an early manifestation of vascular injury, has been shown in patients with ADPKD. Statins have a beneficial effect in the reversal of ED. Th...

journal_title：Renal failure

authors： Namli S,Oflaz H,Turgut F,Alisir S,Tufan F,Ucar A,Mercanoglu F,Ecder T

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Previous studies have demonstrated the role of inflammation in diabetic nephropathy (DN). Neutrophil to lymphocyte ratio (NLR) rather than other white cell parameters was found to be a useful inflammatory marker to predict adverse outcomes in medical and surgical conditions. Nevertheless, the value of NLR in...

journal_title：Renal failure

authors： Azab B,Daoud J,Naeem FB,Nasr R,Ross J,Ghimire P,Siddiqui A,Azzi N,Rihana N,Abdallah M,Azzi N,Patel P,Kleiner M,El-Sayegh S

更新日期：2012-01-01 00:00:00

abstract：:We investigated the mechanism of impaired serum opsonic activity in patients suffering from chronic renal failure (CRF). Prehemodialysis pooled serum from CRF patients was fractionated using Sephadex G-50 gel chromatography, and the effects of the obtained fractions on serum opsonic activity were examined using lumino...

journal_title：Renal failure

authors： Kikuchi T,Nigawara K,Sugawara K,Nakaji S,Abe T,Satoh H

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Transforming growth factor-beta1 (TGF-beta1), the major fibrogenic growth factor, is implicated in the pathogenesis of renal scarring in experimental and clinical nephropathies as well as in chronic allograft nephropathy. In this study we examined the pattern of changes of TGF-beta1 excretion in the urine an...

journal_title：Renal failure

authors： Goumenos DS,Tsakas S,Karavias D,Savidaki I,Karatzas T,Vlachojannis JG

更新日期：2003-07-01 00:00:00

abstract：:Recent studies show that clinically stable renal transplant recipients have an increased prevalence of hyperhomocysteinemia (hyperHcy), but the mechanism of this disorder has not yet been elucidated. The aim of the present study was to evaluate the factors associated with hyperHcy after a successful renal transplantat...

journal_title：Renal failure

authors： Simić-Ogrizović S,Radivojević D,Radovic M,Lezaic V,Mirković D,Babić D,Dukanović L

更新日期：2006-01-01 00:00:00

abstract：:Kidney biopsy is an investigation for diagnosis and prognosis of a variety of nephritides. It also influences therapeutic options. Immunofluorescence (IMF) greatly adds in identifying the pathologies which may not be obvious on light microscopy (L/M), such as IgM, IgA nephropathy, pauci-immune glomerulonephritis, and ...

journal_title：Renal failure

authors： Ali A,Ali MU,Ali MA

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Influenza infection is a significant cause of morbidity and mortality in general population. Hemodialysis patients are considered at high risk of influenza infection given their altered immune status. Pandemic influenza virus is new for human beings, so it is hard to predict the response to infection or vacc...

journal_title：Renal failure

authors： Temiz G,Kasifoglu N,Kiris A,Ozturk S,Sahin G,Yalcin AU,Us T

更新日期：2010-07-01 00:00:00

abstract：:Experimental perfusions of isolated rat kidneys were performed with flow rates adjusted to produce comparable glomerular filtration rates (GFR) in control and experimental groups. The experimental perfusate, consisting of Krebs-Ringer bicarbonate (KRB) containing 3.5% (uncrosslinked) stroma-free hemoglobin (SFH) plus ...

journal_title：Renal failure

authors： Millis RM,Barber JD,Anderson WA,Dehkordi O

更新日期：1995-11-01 00:00:00

abstract：AIM:To investigate the effects of lentivirus-mediated shRNA targeting collagen type I on the mesangial cells of rats and the feasibility of lentivirus-mediated shRNA delivery through renal parenchyma injection. METHODS:Anti-collagen type I shRNA lentiviral vector was constructed, and rat mesangial cells were transfect...

journal_title：Renal failure

authors： Zhou C,Shan Y,Zhao H,He P

更新日期：2011-01-01 00:00:00

abstract：:Creatol (CTL) is a hydroxyl radical adduct of creatinine (Cr). The serum methylguanidine (MG) level and the MG/Cr molar ratio are reported to be biomarkers for oxidative stress. The aim of this study was to examine whether urinary excretion of CTL, another oxidative stress-related marker, is increased in patients with...

journal_title：Renal failure

authors： Ienaga K,Nakamura K,Fujisawa T,Fukunaga Y,Nihei H,Narita M,Tomino Y,Sanaka T,Aoyagi K,Nakano K,Koide H

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:To investigate the anti proteinuric effect of pentoxifylline in diabetic patients, we prospectively studied in 25 hypertensive type 2 diabetic patients with persistent microalbuminuria and normal renal function the impact of combining pentoxifylline with an angiotensin converting enzyme inhibitor, lisinopril,...

journal_title：Renal failure

authors： Harmankaya O,Seber S,Yilmaz M

更新日期：2003-05-01 00:00:00

abstract：:Injectable vitamin D agents are commonly used to manage secondary hyperparathyroidism in dialysis patients. Yet, there are few data documenting the trends and geographic variations in the use of these agents in large, representative samples. We sought to describe patterns and variations in the use of vitamin D formula...

journal_title：Renal failure

authors： Beaubrun AC,Brookhart MA,Sleath B,Wang L,Kshirsagar AV

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Sirolimus has been considered to be a non-nephrotoxic agent. It may delay graft function due to a potential hindrance of the recovery from acute tubular necrosis. It remains controversial as to whether the concomitant administration of sirolimus (SRL) with calcineurin inhibitors delays graft function in Asia...

journal_title：Renal failure

authors： Hsu HJ,Tian YC,Chen YC,Lai BC,Fang JT,Yang CW,Wu MS

更新日期：2008-01-01 00:00:00

abstract：AIM:Occult hepatitis B virus (HBV) infection can be defined as the presence of HBV DNA in the liver and/or blood in the absence of detectable serum hepatitis B surface antigen (HBs Ag). There is a high prevalence of occult HBV infection in dialysis patients. This study investigated the prevalence of occult HBV infectio...

journal_title：Renal failure

authors： Sav T,Gursoy S,Torun E,Sav NM,Unal A,Oymak O,Utas C

更新日期：2010-01-01 00:00:00