Abstract:
:The effects of various psychomotor stimulant drugs and drugs outside this class were examined on the efficacy of stimuli previously paired with reinforcement or reward (conditioned reinforcers, CR) in controlling responding. Pipradrol (5-45 mumol/kg), d-amphetamine (1.25-15.0 mumol/kg), and the cocaine analogues WIN 35,428 (0.1-30.0 mumol/kg) and in one of two determinations WIN 35,065-2 (0.1-29.0 mumol/kg) all generally increased responding on a lever providing CR, but did not change or decreased responding on a lever providing no CR (NCR). Cocaine (5-125 mumol/kg) and chlordiazepoxide (3.75-60.0 mumol/kg) had no significant effects. Morphine (3.2-32.0 mumol/kg) and alpha-flupenthixol (0.02-2.0 mumol/kg) generally reduced responding on both levers. Apomorphine (0.1-1.0 mumol/kg) generally increased responding on both levers. Neurochemical data showed that d-amphetamine was generally more potent than pipradrol in its effects on in vitro monoamine uptake and release.
journal_name
Psychopharmacology (Berl)journal_title
Psychopharmacologyauthors
Robbins TW,Watson BA,Gaskin M,Ennis Cdoi
10.1007/BF00427952subject
Has Abstractpub_date
1983-01-01 00:00:00pages
113-9issue
2eissn
0033-3158issn
1432-2072journal_volume
80pub_type
杂志文章abstract::Chronic nicotine infusion has been found in a series of studies in our laboratory to significantly improve choice accuracy of rats in the eight-arm radial maze. The current study was designed to compare the effects of chronic nicotine infusion on working and reference memory in a 16-arm radial maze. Nicotine was admin...
journal_title:Psychopharmacology
pub_type: 杂志文章
doi:10.1007/BF02805971
更新日期:1996-09-01 00:00:00
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journal_title:Psychopharmacology
pub_type: 杂志文章
doi:10.1007/BF00172881
更新日期:1986-01-01 00:00:00
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doi:10.1007/s00213-020-05596-8
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journal_title:Psychopharmacology
pub_type: 杂志文章
doi:10.1007/BF00429198
更新日期:1981-01-01 00:00:00
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journal_title:Psychopharmacology
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doi:10.1007/BF00427282
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journal_title:Psychopharmacology
pub_type: 杂志文章
doi:10.1007/BF00216053
更新日期:1988-01-01 00:00:00
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pub_type: 杂志文章,多中心研究,随机对照试验
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journal_title:Psychopharmacology
pub_type: 杂志文章,评审
doi:10.1007/s00213-013-3423-z
更新日期:2014-09-01 00:00:00
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doi:10.1007/BF00181959
更新日期:1988-01-01 00:00:00
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journal_title:Psychopharmacology
pub_type: 杂志文章
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更新日期:1981-01-01 00:00:00
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doi:10.1007/s00213-003-1526-7
更新日期:2003-11-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.1007/s00213-009-1591-7
更新日期:2009-11-01 00:00:00
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journal_title:Psychopharmacology
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更新日期:2001-07-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/s00213-002-1233-9
更新日期:2002-12-01 00:00:00
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更新日期:2008-04-01 00:00:00
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journal_title:Psychopharmacology
pub_type: 杂志文章
doi:10.1007/BF00428314
更新日期:1979-01-01 00:00:00
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journal_title:Psychopharmacology
pub_type: 杂志文章,随机对照试验
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更新日期:2012-09-01 00:00:00
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journal_title:Psychopharmacology
pub_type: 杂志文章
doi:10.1007/BF00216063
更新日期:1988-01-01 00:00:00
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journal_title:Psychopharmacology
pub_type: 杂志文章
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更新日期:1997-06-01 00:00:00
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pub_type: 杂志文章
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更新日期:1993-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:1993-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/s00213-008-1122-y
更新日期:2008-09-01 00:00:00
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journal_title:Psychopharmacology
pub_type: 杂志文章
doi:10.1007/BF00432441
更新日期:1981-01-01 00:00:00
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doi:10.1007/s00213-013-3161-2
更新日期:2013-12-01 00:00:00
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journal_title:Psychopharmacology
pub_type: 杂志文章
doi:10.1007/BF00518177
更新日期:1987-01-01 00:00:00
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journal_title:Psychopharmacology
pub_type: 杂志文章
doi:10.1007/s00213-004-2060-y
更新日期:2005-05-01 00:00:00
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journal_title:Psychopharmacology
pub_type: 杂志文章
doi:10.1007/s002130100833
更新日期:2001-10-01 00:00:00
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journal_title:Psychopharmacology
pub_type: 杂志文章
doi:10.1007/s002130050811
更新日期:1999-01-01 00:00:00
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journal_title:Psychopharmacology
pub_type: 杂志文章
doi:10.1007/BF00426919
更新日期:1979-05-08 00:00:00
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journal_title:Psychopharmacology
pub_type: 杂志文章
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更新日期:2013-08-01 00:00:00