Unique species of mRNA from adenovirus type 7 early region 1 in cells transformed by adenovirus type 7 DNA fragment.

abstract：:A panel of seven monoclonal antibodies against the relatively conserved CD4-binding domain on human immunodeficiency virus type 1 (HIV-1) gp120 was generated by immunizing mice with purified gp120. These monoclonal antibodies reacted specifically with gp120 in an enzyme-linked immunosorbent assay and Western blots (im...

journal_title：Journal of virology

authors： Sun NC,Ho DD,Sun CR,Liou RS,Gordon W,Fung MS,Li XL,Ting RC,Lee TH,Chang NT

更新日期：1989-09-01 00:00:00

abstract：:Control of HIV-1 replication following nonsterilizing HIV-1 vaccination could be achieved by vaccine-elicited CD8(+) T-cell-mediated antiviral activity. To date, neither the functional nor the phenotypic profiles of CD8(+) T cells capable of this activity are clearly understood; consequently, little is known regarding...

journal_title：Journal of virology

authors： Freel SA,Lamoreaux L,Chattopadhyay PK,Saunders K,Zarkowsky D,Overman RG,Ochsenbauer C,Edmonds TG,Kappes JC,Cunningham CK,Denny TN,Weinhold KJ,Ferrari G,Haynes BF,Koup RA,Graham BS,Roederer M,Tomaras GD

更新日期：2010-05-01 00:00:00

abstract：:The viral dynamics in human immunodeficiency virus type 1 (HIV-1) infection have been studied extensively using mathematical modeling, but data from other primate lentivirus systems are scarce. This study was initiated to increase the understanding of the differences and similarities between the different primate lent...

journal_title：Journal of virology

authors： Brandin E,Thorstensson R,Bonhoeffer S,Albert J

更新日期：2006-10-01 00:00:00

abstract：:The membrane-associated alphavirus RNA replication complex contains four virus-encoded subunits, the nonstructural proteins nsP1 to nsP4. Semliki Forest virus (SFV) nsP1 is hydrophobically modified by palmitoylation of cysteines 418 to 420. Here we show that Sindbis virus nsP1 is also palmitoylated on the same site (c...

journal_title：Journal of virology

authors： Ahola T,Kujala P,Tuittila M,Blom T,Laakkonen P,Hinkkanen A,Auvinen P

更新日期：2000-08-01 00:00:00

abstract：:The trans-activator Tat proteins coded by human immunodeficiency virus type 1 (HIV-1) and HIV-2 appear to be similar in structure and function. However, the Tat protein of HIV-2 (Tat2) activates the HIV-1 long terminal repeat (LTR) less efficiently than Tat1 (M. Emerman, M. Guyader, L. Montagnier, D. Baltimore, and M....

journal_title：Journal of virology

authors： Elangovan B,Subramanian T,Chinnadurai G

更新日期：1992-04-01 00:00:00

abstract：:Noroviruses account for 96% of viral gastroenteritis cases worldwide, with GII.4 strains responsible >80% of norovirus outbreaks. Histo-blood group antigens (HBGAs) are norovirus binding ligands, and antigenic and preferential HBGA binding profiles vary over time as new GII.4 strains emerge. The capsid P2 subdomain fa...

journal_title：Journal of virology

authors： Debbink K,Donaldson EF,Lindesmith LC,Baric RS

更新日期：2012-01-01 00:00:00

abstract：:Rhesus rhadinovirus (RRV) is a gammaherpesvirus closely related to Kaposi's sarcoma-associated herpesvirus (KSHV), an oncogenic virus linked to the development of Kaposi's sarcoma and several other lymphoproliferative diseases, including primary effusion lymphoma and multicentric Castleman's disease. RRV naturally inf...

journal_title：Journal of virology

authors： Zhang W,Zhou F,Greene W,Gao SJ

更新日期：2010-11-01 00:00:00

abstract：:The nuclear localization of the herpes simplex virus transcriptional activator protein ICP4 was studied by indirect immunofluorescence. At early times after viral infection, ICP4 quickly localized to a diffuse intranuclear distribution. ICP4 later concentrated in globular compartments within the nucleus. The redistrib...

journal_title：Journal of virology

authors： Knipe DM,Senechek D,Rice SA,Smith JL

更新日期：1987-02-01 00:00:00

abstract：:Murine gammaherpesvirus 68 (gammaHV68) provides an important experimental model for understanding mechanisms of immune control of the latent human gammaherpesviruses. Antiviral CD8 T cells play a key role throughout three separate phases of the infection: clearance of lytic virus, control of the latency amplification ...

journal_title：Journal of virology

authors： Freeman ML,Lanzer KG,Cookenham T,Peters B,Sidney J,Wu TT,Sun R,Woodland DL,Sette A,Blackman MA

更新日期：2010-03-01 00:00:00

abstract：:A promoter-trap retrovirus has been constructed in which a promoterless polyomavirus middle T antigen gene was inserted in the U3 region of the long terminal repeat of a replication-competent Moloney murine leukemia virus. The resulting virus, designated PyT, was used to infect mouse mammary glands in situ. As expecte...

journal_title：Journal of virology

authors： Coulombe J,Avis Y,Gray DA

更新日期：1996-10-01 00:00:00

abstract：:Following its entry into cells, pseudorabies virus (PRV) utilizes microtubules to deliver its nucleocapsid to the nucleus. Previous studies have shown that PRV VP1/2 is an effector of dynein-mediated capsid transport. However, the mechanism of PRV for recruiting microtubule motor proteins for successful neuroinvasion ...

journal_title：Journal of virology

authors： Yan K,Liu J,Guan X,Yin YX,Peng H,Chen HC,Liu ZF

更新日期：2019-03-21 00:00:00

abstract：:We investigated how the broadly neutralizing monoclonal antibody 2F5 affects the human immunodeficiency virus type 1 envelope glycoprotein as it undergoes receptor-induced conformational changes and show that 2F5 binds both native and fusion-intermediate conformations, suggesting inhibition of a late step in virus ent...

journal_title：Journal of virology

authors： de Rosny E,Vassell R,Jiang S,Kunert R,Weiss CD

更新日期：2004-03-01 00:00:00

abstract：:Therapeutic strategies for the treatment of acute retroviral infections have relied mainly on antiviral drugs. In this study we used the Friend virus model system to demonstrate that enhancement of the immune system can also have dramatic therapeutic effects. Since resistance to Friend virus-induced leukemia in mice i...

journal_title：Journal of virology

authors： Olbrich AR,Schimmer S,Heeg K,Schepers K,Schumacher TN,Dittmer U

更新日期：2002-11-01 00:00:00

abstract：:The herpes simplex virus 1 (HSV-1) infected-cell protein 0 (ICP0) has the characteristics of a promiscuous transactivator of genes introduced into cells by infection or transfection. To identify cellular proteins interacting with ICP0, we used a domain of exon II of ICP0 that is known to be crucial for regulatory func...

journal_title：Journal of virology

authors： Kawaguchi Y,Van Sant C,Roizman B

更新日期：1997-10-01 00:00:00

abstract：:The infection of cells which belong to the B-cell lineage is thought to be the primary event leading to the phenotypic and functional alterations seen in the murine AIDS (M. Huang, C. Simard, D. Kay, and P. Jolicoeur, J. Virol. 65:6562-6571, 1991). Using in situ hybridization, we studied the time course of the anatomi...

journal_title：Journal of virology

authors： Simard C,Huang M,Jolicoeur P

更新日期：1994-03-01 00:00:00

abstract：:N(pro) is a multifunctional autoprotease unique to pestiviruses. The interacting partners of the N(pro) protein of classical swine fever virus (CSFV), a swine pestivirus, have been insufficiently defined. Using a yeast two-hybrid screen, we identified poly(C)-binding protein 1 (PCBP1) as a novel interacting partner of...

journal_title：Journal of virology

authors： Li D,Li S,Sun Y,Dong H,Li Y,Zhao B,Guo D,Weng C,Qiu HJ

更新日期：2013-02-01 00:00:00

abstract：:Glycoproteins homologous to glycoprotein B (gB) of herpes simplex virus constitute the most highly conserved group of herpesvirus glycoproteins. This strong conservation of amino acid sequences might be indicative of a common functional role. Indeed, gB homologs have been implicated in the processes of viral entry and...

journal_title：Journal of virology

authors： Kopp A,Mettenleiter TC

更新日期：1992-05-01 00:00:00

abstract：:The complete genome sequences of two Sulfolobus spindle-shaped viruses (SSVs) from acidic hot springs in Kamchatka (Russia) and Yellowstone National Park (United States) have been determined. These nonlytic temperate viruses were isolated from hyperthermophilic Sulfolobus hosts, and both viruses share the spindle-shap...

journal_title：Journal of virology

authors： Wiedenheft B,Stedman K,Roberto F,Willits D,Gleske AK,Zoeller L,Snyder J,Douglas T,Young M

更新日期：2004-02-01 00:00:00

abstract：:The human immunodeficiency virus (HIV) integrase protein (IN) catalyzes two reactions required to integrate HIV DNA into the human genome: 3' processing of the viral DNA ends and integration. IN has three domains, the N-terminal zinc-binding domain, the catalytic core, and the C-terminal SH3 domain. Previously, it was...

journal_title：Journal of virology

authors： van den Ent FM,Vos A,Plasterk RH

更新日期：1999-04-01 00:00:00

abstract：:The human immunodeficiency virus type 1 (HIV-1)-encoded RNA-binding protein Tat is known to play an essential role in viral gene expression. In the search for novel compounds to inhibit Tat transactivity, one coumarin derivative, BPRHIV001, was identified, with a 50% effective concentration (EC(50)) against HIV-1 at 1...

journal_title：Journal of virology

authors： Lin PH,Ke YY,Su CT,Shiao HY,Hsieh HP,Chao YK,Lee CN,Kao CL,Chao YS,Chang SY

更新日期：2011-09-01 00:00:00

abstract：:Highly active antiretroviral therapy (HAART) enables long-term suppression of plasma HIV-1 loads in infected persons, but low-level virus persists and rebounds following cessation of therapy. During HAART, this virus resides in latently infected cells, such as resting CD4(+) T cells, and in other cell types that may s...

journal_title：Journal of virology

authors： North TW,Higgins J,Deere JD,Hayes TL,Villalobos A,Adamson L,Shacklett BL,Schinazi RF,Luciw PA

更新日期：2010-03-01 00:00:00

abstract：:The immune response to bovine herpesvirus 1 (BHV-1) infection can protect cattle from subsequent challenge with the virus. This protection involves a variety of defensive strategies, and the activation of most of these defenses requires the recognition of viral proteins by the cellular immune system. To identify some ...

journal_title：Journal of virology

authors： Hutchings DL,van Drunen Littel-van den Hurk S,Babiuk LA

更新日期：1990-10-01 00:00:00

abstract：:Hepatitis delta virus (HDV) is a defective RNA virus which is dependent on hepatitis B virus for essential helper functions. Only a single highly basic phosphoprotein, HDV antigen (HDAg), is expressed by the HDV genome during infection in humans. Antibody directed to HDAg is important in the diagnosis of HDV infection...

journal_title：Journal of virology

authors： Wang JG,Jansen RW,Brown EA,Lemon SM

更新日期：1990-03-01 00:00:00

abstract：:An immunochemical analysis of the hemagglutinin (VP4) of the simian rotavirus SA11 was performed to better understand the structure and function of this molecule. Following immunization of mice with double-shelled virus particles and VP4-enriched fractions from CsCl gradients, a battery of anti-SA11 hybridomas was gen...

journal_title：Journal of virology

authors： Burns JW,Greenberg HB,Shaw RD,Estes MK

更新日期：1988-06-01 00:00:00

abstract：UNLABELLED:Rotaviruses (RVs) are 11-segmented, double-stranded RNA viruses that cause severe gastroenteritis in children. In addition to an error-prone genome replication mechanism, RVs can increase their genetic diversity by reassorting genes during host coinfection. Such exchanges allow RVs to acquire advantageous ge...

journal_title：Journal of virology

authors： Zhang S,McDonald PW,Thompson TA,Dennis AF,Akopov A,Kirkness EF,Patton JT,McDonald SM

更新日期：2014-09-01 00:00:00

abstract：:The inclusion of Mimiviridae members in the putative monophyletic nucleocytoplasmic large DNA virus (NCLDV) group is based on genomic and phylogenomic patterns. This shows that, along with other viral families, they share a set of genes known as core or "hallmark genes," including the gene for the major capsid protein...

journal_title：Journal of virology

authors： Boratto PVM,Dornas FP,da Silva LCF,Rodrigues RAL,Oliveira GP,Cortines JR,Drumond BP,Abrahão JS

更新日期：2018-01-02 00:00:00

abstract：:Apoptosis is a type of controlled cell death that is essential for development and tissue homeostasis. It also serves as a robust host response against infection by many viruses. The capacity of neurotropic viruses to induce apoptosis strongly correlates with virulence. However, the precise function of apoptosis in vi...

journal_title：Journal of virology

authors： Pruijssers AJ,Hengel H,Abel TW,Dermody TS

更新日期：2013-12-01 00:00:00

abstract：:Anelloviruses are a group of single-stranded circular DNA viruses infecting humans and other animal species. Animal models combined with reverse genetic systems of anellovirus have not been developed. We report here the construction and initial characterization of full-length DNA clones of a porcine anellovirus, torqu...

journal_title：Journal of virology

authors： Huang YW,Patterson AR,Opriessnig T,Dryman BA,Gallei A,Harrall KK,Vaughn EM,Roof MB,Meng XJ

更新日期：2012-06-01 00:00:00

abstract：:Herpes simplex virus (HSV)-infected cells can activate the human complement system without interference of specific anti-HSV antibodies. Analysis by flow cytometry showed that C3-like molecules were deposited on the membrane of the infected cell when incubated with human serum without specific antibodies. Depletion of...

journal_title：Journal of virology

authors： van Strijp JA,van Kessel KP,Miltenburg LA,Fluit AC,Verhoef J

更新日期：1988-03-01 00:00:00

abstract：:We previously described a monoclonal antibody (Y8-10C2) that binds influenza virus hemagglutinin (HA) monomers but not native trimers. In this study, we demonstrated that Y8-10C2 binds to the globular domain of HA and found evidence that its epitope is located at the interface of adjacent subunits. We further showed t...

journal_title：Journal of virology

authors： Yewdell JW,Taylor A,Yellen A,Caton A,Gerhard W,Bächi T

更新日期：1993-02-01 00:00:00