Comparative genomic analysis of hyperthermophilic archaeal Fuselloviridae viruses.

abstract：UNLABELLED:Noroviruses are the leading cause of acute gastroenteritis outbreaks worldwide. The majority of norovirus outbreaks are caused by genogroup II.4 (GII.4). Novel GII.4 strains emerge every 2 to 4 years and replace older variants as the dominant norovirus. Novel variants emerge through a combination of recombin...

journal_title：Journal of virology

authors： Vega E,Donaldson E,Huynh J,Barclay L,Lopman B,Baric R,Chen LF,Vinjé J

更新日期：2014-12-01 00:00:00

abstract：UNLABELLED:Broadly neutralizing antibodies (bNAbs) specific for conserved epitopes on the HIV-1 envelope (Env) are believed to be essential for protection against multiple HIV-1 clades. However, vaccines capable of stimulating the production of bNAbs remain a major challenge. Given that polyreactivity and autoreactivit...

journal_title：Journal of virology

authors： Gupta S,Clark ES,Termini JM,Boucher J,Kanagavelu S,LeBranche CC,Abraham S,Montefiori DC,Khan WN,Stone GW

更新日期：2015-04-01 00:00:00

abstract：:The possible addition of extra sequences to simian virus 40 (SV40) DNA was analyzed by electron microscopy in two different cell systems, productively infected monkey cells and activated heterokaryons on monkey and transformed mouse 3T3 cells. We found that the closed circular DNA fraction, extracted from monkey cells...

journal_title：Journal of virology

authors： Yoshike K,Defendi V

更新日期：1977-08-01 00:00:00

abstract：:The antiviral effects of nitric oxide (NO) on Japanese encephalitis virus (JEV), a member of the family Flaviviridae, were investigated in this study. In vitro, inhibition of replication of JEV in gamma interferon-activated RAW 264.7 murine macrophages was correlated to cellular NO production. When cocultured with inf...

journal_title：Journal of virology

authors： Lin YL,Huang YL,Ma SH,Yeh CT,Chiou SY,Chen LK,Liao CL

更新日期：1997-07-01 00:00:00

abstract：:Bacteriophages of the C3 morphotype, characterized by very long heads that exceed their width several times, are extremely rare among the Podoviridae family members and constitute only 0.5% of over 5,500 phages that have been examined by the electron microscope (H. W. Ackermann, Arch. Virol. 152:227-243, 2007; H. W. A...

journal_title：Journal of virology

authors： Li Y,Chen M,Tang F,Yao H,Lu C,Zhang W

更新日期：2012-12-01 00:00:00

abstract：:Recent evidence supports a role for vitamin K-dependent coagulation zymogens in adenovirus serotype 5 (Ad5, subgroup C) infection of hepatocytes. Here, we assessed the effect of virus-zymogen interaction on cellular transduction using a panel of fiber (f)-pseudotyped viruses derived from subgroup D (f47, f33, f24, f45...

journal_title：Journal of virology

authors： Parker AL,McVey JH,Doctor JH,Lopez-Franco O,Waddington SN,Havenga MJ,Nicklin SA,Baker AH

更新日期：2007-04-01 00:00:00

abstract：:A widespread porcine epidemic diarrhea virus (PEDV) occurred in southern China during 2010 to 2012. A virulent field PEDV strain, GD-B, was isolated from a sucking piglet suffering from severe diarrhea in Guangdong, China. We sequenced and analyzed the complete genome of strain GD-B, which will promote a better unders...

journal_title：Journal of virology

authors： Luo Y,Zhang J,Deng X,Ye Y,Liao M,Fan H

更新日期：2012-09-01 00:00:00

abstract：:The induction of a unique macrophage procoagulant molecule by murine hepatitis virus strain 3 correlates with the severity of viral hepatitis. The role of tyrosine phosphorylation in the signalling pathway leading to procoagulant expression was studied. Murine hepatitis virus strain 3 initiated a rapid increase in pho...

journal_title：Journal of virology

authors： Dackiw AP,Zakrzewski K,Nathens AB,Cheung PY,Fingerote R,Levy GA,Rotstein OD

更新日期：1995-09-01 00:00:00

abstract：:Inhibitors of hemagglutination by type A2 influenza virus and a recently isolated strain of type B influenza virus were separated by sucrose density gradient centrifugation and agarose gel filtration from horse serum. Using selected reagents, it was demonstrated that the active substituent on the horse serum inhibitor...

journal_title：Journal of virology

authors： Levinson B,Pepper D,Belyavin G

更新日期：1969-05-01 00:00:00

abstract：:A protein-protein interaction within the helicase domain of the Tobacco mosaic virus (TMV) 126- and 183-kDa replicase proteins was previously implicated in virus replication (S. Goregaoker, D. Lewandowski, and J. Culver, Virology 282:320-328, 2001). To further characterize the interaction, polypeptides covering the in...

journal_title：Journal of virology

authors： Goregaoker SP,Culver JN

更新日期：2003-03-01 00:00:00

abstract：:Influenza A viruses cause severe respiratory illnesses in humans and animals. Overreaction of the innate immune response to influenza virus infection results in hypercytokinemia, which is responsible for mortality and morbidity. However, the mechanism by which influenza induces hypercytokinemia is not fully understood...

journal_title：Journal of virology

authors： Ma N,Li X,Jiang H,Dai Y,Xu G,Zhang Z

更新日期：2021-01-13 00:00:00

abstract：:A bacteriophage with a contractile tail which shows very similar features to R-type pyocins was isolated and characterized. This phage, named PS17,was purified by DEAE-cellulose chromatography and CsCl density gradient centrifugation. It was a DNA-containing phage, and the density of the purified particles in CsCl was...

journal_title：Journal of virology

authors： Kageyama M,Shinomiya T,Aihara Y,Kobayashi M

更新日期：1979-12-01 00:00:00

abstract：:The cellular transcription factors Sp1 and NF-kappaB were upregulated shortly after the binding of purified live or UV-inactivated human cytomegalovirus (HCMV) to the cell surface. The rapid time frame of transcription factor induction is similar to that seen in other systems in which cellular factors are induced foll...

journal_title：Journal of virology

authors： Yurochko AD,Hwang ES,Rasmussen L,Keay S,Pereira L,Huang ES

更新日期：1997-07-01 00:00:00

abstract：:The RNA-dependent RNA polymerase of influenza A virus is composed of three subunits that together synthesize all viral mRNAs and also replicate the viral genomic RNA segments (vRNAs) through intermediates known as cRNAs. Here we describe functional characterization of 16 site-directed mutants of one polymerase subunit...

journal_title：Journal of virology

authors： Regan JF,Liang Y,Parslow TG

更新日期：2006-01-01 00:00:00

abstract：:Retroviruses integrate into cellular DNA nonrandomly. Lentiviruses such as human immunodeficiency virus type 1 (HIV-1) favor the bodies of active genes and gene-enriched transcriptionally active regions of chromosomes. The interaction between lentiviral integrase and the cellular protein lens epithelium-derived growth...

journal_title：Journal of virology

authors： Koh Y,Wu X,Ferris AL,Matreyek KA,Smith SJ,Lee K,KewalRamani VN,Hughes SH,Engelman A

更新日期：2013-01-01 00:00:00

abstract：:We have measured in 22 asymptomatic human immunodeficiency virus type 1-infected patients (10 rapid progressors and 12 slow progressors) the proviral load of CD4(+) T cells homogeneously superinfected by the same dose of a non-syncytium-inducing virus in the presence or in the absence of autologous CD8(+) T cells. We ...

journal_title：Journal of virology

authors： Salerno-Gonçalves R,Lu W,Andrieu JM

更新日期：2000-07-01 00:00:00

abstract：:Human metapneumovirus (HMPV) has recently been identified as a significant cause of serious respiratory tract disease in humans. In particular, the emerging information on the contribution of HMPV to pediatric respiratory tract disease suggests that it will be important to develop a vaccine against this virus for use ...

journal_title：Journal of virology

authors： Biacchesi S,Skiadopoulos MH,Yang L,Lamirande EW,Tran KC,Murphy BR,Collins PL,Buchholz UJ

更新日期：2004-12-01 00:00:00

abstract：:The relationship between immunosenescence and the host response to virus infection is poorly understood at the molecular level. Two different patterns of pulmonary host responses to virus were observed when gene expression profiles from severe acute respiratory syndrome coronavirus (SARS-CoV)-infected young mice that ...

journal_title：Journal of virology

authors： Baas T,Roberts A,Teal TH,Vogel L,Chen J,Tumpey TM,Katze MG,Subbarao K

更新日期：2008-10-01 00:00:00

abstract：:We investigated the features of the Moloney murine sarcoma virus leader sequence necessary for RNA packaging function by using a deletion analysis approach. We found that sequences that extend beyond those characterized genetically in previous reports are important for optimal packaging efficiency. A fragment covering...

journal_title：Journal of virology

authors： Izmailova E,Aldovini A

更新日期：2002-05-01 00:00:00

abstract：:Protein kinase activity is associated with both the extracellular and the occluded forms of Autographa californica nuclear polyhedrosis virus, a baculovirus. Serine and threonine are the predominant amino acids phosphorylated by the kinase activity associated with both viral forms; no phosphotyrosine was detected. The...

journal_title：Journal of virology

authors： Miller LK,Adang MJ,Browne D

更新日期：1983-04-01 00:00:00

abstract：:Herpesviruses encode an essential, maturational serine protease whose catalytic domain, assemblin (28 kDa), is released by self-cleavage from a 74-kDa precursor (pPR, pUL80a). Although there is considerable information about the structure and enzymatic characteristics of assemblin, a potential pharmacologic target, co...

journal_title：Journal of virology

authors： Brignole EJ,Gibson W

更新日期：2007-04-01 00:00:00

abstract：:Viral infection induces production of type I interferons (IFNs), which stimulate the expression of a variety of antiviral factors to inhibit viral replication. To establish effective infection, viruses need to develop strategies to evade the immune responses. A neurovirulent Sindbis virus strain with neuroinvasive pro...

journal_title：Journal of virology

authors： Wang X,Li MMH,Zhao J,Li S,MacDonald MR,Rice CM,Gao X,Gao G

更新日期：2016-10-28 00:00:00

abstract：UNLABELLED:Children with acute respiratory syncytial virus (RSV) infection often develop sequelae of persistent airway inflammation and wheezing. Pulmonary C fibers (PCFs) are involved in the generation of airway inflammation and resistance; however, their role in persistent airway diseases after RSV is unexplored. Her...

journal_title：Journal of virology

authors： Zang N,Zhuang J,Deng Y,Yang Z,Ye Z,Xie X,Ren L,Fu Z,Luo Z,Xu F,Liu E

更新日期：2015-12-16 00:00:00

abstract：:A uniform nomenclature has been agreed upon for monoclonal antibodies directed against virus-coded proteins of simian virus 40 and polyoma virus. Blocks of numbers from PAb1 to PAb999 have been allocated to workers involved in the isolation of monoclonal antibodies of this type. The correspondence between PAb numbers ...

journal_title：Journal of virology

authors： Crawford L,Harlow E

更新日期：1982-02-01 00:00:00

abstract：:Infectious bursal disease virus (IBDV) is a nonenveloped virus with an icosahedral capsid composed of two proteins, VP2 and VP3, that derive from the processing of the polyprotein NH(2)-pVP2-VP4-VP3-COOH. The virion contains VP1, the viral polymerase, which is both free and covalently linked to the two double-stranded...

journal_title：Journal of virology

authors： Chevalier C,Lepault J,Da Costa B,Delmas B

更新日期：2004-04-01 00:00:00

abstract：:Purified Semliki Forest virus (SFV) contains three structural proteins while its core (nucleocapsid) contains two of these proteins. To identify all of the proteins synthesized under virus direction, cells were infected with SFV in the presence of actinomycin D and guanidine. Cell protein synthesis was markedly and ir...

journal_title：Journal of virology

authors： Friedman RM

更新日期：1968-10-01 00:00:00

abstract：:Vaccinia virus genes are expressed in a sequential fashion, suggesting a role for negative as well as positive regulatory mechanisms. A potential down regulator of gene expression was mapped by transfection assays to vaccinia virus open reading frame D10, which encodes a protein with no previously known function. Inhi...

journal_title：Journal of virology

authors： Shors T,Keck JG,Moss B

更新日期：1999-01-01 00:00:00

abstract：:West Nile virus (WNV) is a neurotropic flavivirus and the leading cause of mosquito-borne encephalitis in the United States. Recent studies in humans have found that dysfunctional T cell responses strongly correlate with development of severe WNV neuroinvasive disease. However, the contributions of human dendritic cel...

journal_title：Journal of virology

authors： Zimmerman MG,Bowen JR,McDonald CE,Pulendran B,Suthar MS

更新日期：2019-11-13 00:00:00

abstract：:Hepatitis B virus particles contain three related viral envelope proteins, the small, middle, and large S (surface) proteins. All three proteins contain the small S amino acid sequence at their carboxyl terminus. It is not clear which of these S proteins functions as the viral attachment protein, binding to a target c...

journal_title：Journal of virology

authors： Pontisso P,Petit MA,Bankowski MJ,Peeples ME

更新日期：1989-05-01 00:00:00

abstract：UNLABELLED:Enteroviruses (EVs) are a genetically and antigenically diverse group of viruses infecting humans. A mostly distinct set of EV variants have additionally been documented to infect wild apes and several, primarily captive, Old World monkey (OWM) species. To investigate the prevalence and genetic characteristi...

journal_title：Journal of virology

authors： Van Nguyen D,Harvala H,Ngole EM,Delaporte E,Woolhouse ME,Peeters M,Simmonds P

更新日期：2014-06-01 00:00:00