Abstract:
:A controlled trial was carried out to assess the value of intensive plasma exchange in 27 renal transplant recipients with clinical and histological evidence of acute vascular rejection. In addition to standard immunosuppression, 13 patients received plasma exchange on six consecutive days at a mean exchange volume of 40.6 ml/kg of body weight each day using an intermittent cell separator. A further 14 patients received standard immunosuppression only. In addition, 10 patients exchanged prior to the controlled trial have been studied. Analysis of short-term benefit, as evidenced by a reduction in serum creatinine, and by subsequent graft survival revealed no significant difference in these parameters between the two groups in the controlled trial. This regimen of plasma exchange has not, therefore, been shown to modify acute renal allograft rejection.
journal_name
Transplantationjournal_title
Transplantationauthors
Allen NH,Dyer P,Geoghegan T,Harris K,Lee HA,Slapak Mdoi
10.1097/00007890-198305000-00006subject
Has Abstractpub_date
1983-05-01 00:00:00pages
425-8issue
5eissn
0041-1337issn
1534-6080journal_volume
35pub_type
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