Impact of parathyroid hormone on bone density in long-term renal transplant patients with good graft function.

abstract：BACKGROUND:Graft coronary artery disease (CAD) is an increasingly important problem during long-term survival after heart transplantation, but the importance of cellular rejection, in particular late after transplantation, remains undetermined. METHODS AND RESULTS:We analyzed 492 coronary angiographies (967+/-705 days...

journal_title：Transplantation

authors： Brunner-La Rocca HP,Schneider J,Künzli A,Turina M,Kiowski W

更新日期：1998-02-27 00:00:00

abstract：:In recent years there have been major advances in the technology for the detection and definition of human leukocyte antigen antibodies. In this overview we describe the evolution in laboratory technology, the techniques currently available and consider their application in antibody specificity definition and in under...

journal_title：Transplantation

authors： Fuggle SV,Martin S

更新日期：2008-08-15 00:00:00

abstract：:Cytomegalovirus disease is an important cause of morbidity following liver transplantation. To date there has not been an effective prophylaxis for CMV disease after liver transplantation. One hundred forty-three patients were randomized to receive either high dose oral acyclovir (800 mg 4 times a day) alone for 3 mon...

journal_title：Transplantation

authors： Martin M,Mañez R,Linden P,Estores D,Torre-Cisneros J,Kusne S,Ondick L,Ptachcinski R,Irish W,Kisor D

更新日期：1994-10-15 00:00:00

abstract：BACKGROUND:Upon the availability of a cadaveric donor kidney, a delicate allocation process precedes every transplantation. A remodeled Eurotransplant Kidney Allocation System (ETKAS)-derived from simulation studies-was installed in March 1996. The purpose was to adjust long waiting times and international exchange bal...

journal_title：Transplantation

authors： De Meester J,Persijn GG,Wujciak T,Opelz G,Vanrenterghem Y

更新日期：1998-11-15 00:00:00

abstract：:Although FK506 has been widely investigated as a potent suppressor of organ allograft rejection in animals, little is known about the effect of FK506 on T cell responses to allografts in vivo. In the present study, we have studied the effect of FK506 on the induction of allocytolytic T lymphocyte using mice primed wit...

journal_title：Transplantation

authors： Maruyama M,Suzuki H,Yamashita N,Yano S

更新日期：1990-08-01 00:00:00

abstract：BACKGROUND:Acute graft dysfunction caused by ischemia-reperfusion injury is recognized as a major source of morbidity and mortality following adult heart transplantation. The aim of this study was to determine whether treating the donor and recipient with cariporide, an inhibitor of the sodium-hydrogen exchanger, could...

journal_title：Transplantation

authors： Ryan JB,Hicks M,Cropper JR,Garlick SR,Kesteven SH,Wilson MK,Feneley MP,Macdonald PS

更新日期：2003-03-15 00:00:00

abstract：:Adult bone marrow-derived mesenchymal stem cells (MSCs) are multipotential cells capable of regenerating injured tissues. In addition to their multipotency, MSCs inhibit natural killer cell cytotoxicity and T-lymphocyte alloproliferation. Several immunosuppressive mechanisms have been described, including indoleamine ...

journal_title：Transplantation

authors： Selmani Z,Naji A,Gaiffe E,Obert L,Tiberghien P,Rouas-Freiss N,Carosella ED,Deschaseaux F

更新日期：2009-05-15 00:00:00

abstract：:Experiments were performed on the quality of renal functional recovery after 24, 48, or 72-hr hypothermic storage preservation of canine kidneys in Euro-Collins solution (EC), Collins' solution C2, hypertonic citrate solutions (HC, HC-D2O), or our new flush solution 2 (F.2). Clearance tests (inulin, paraaminohippuric ...

journal_title：Transplantation

authors： Fischer JH,Knupfer P,Beyer M

更新日期：1985-02-01 00:00:00

abstract：:Seventy-two dog kidneys were stored under hypothermia as described by Collins and Sacks between 24 and 72 hr and then transplanted. The immediate function of the kidneys was measured by p-aminohippuric acid and inulin clearances. Twenty-four hr proved to be the maximum safe preservation time with both methods. The imm...

journal_title：Transplantation

authors： Grundmann R,Strümper R,Eichmann J,Pichlmaier H

更新日期：1977-05-01 00:00:00

abstract：BACKGROUND:Obesity is a common problem following renal transplantation. Rimonabant, a cannabinoid-1 receptor blocker, offers a new approach for reducing obesity. METHODS:The potential pharmacokinetic interaction between rimonabant and cyclosporine A (CsA, n=10) and tacrolimus (Tac, n=8) was assessed in stable renal tr...

journal_title：Transplantation

authors： Amundsen R,Asberg A,Robertsen I,Vethe NT,Bergan S,Hartmann A,Midtvedt K

更新日期：2009-04-27 00:00:00

abstract：:The effects of dietary (10% calories) safflower (SAF), evening primrose (EPO), and fish oil (F) as sources of linoleic acid (control), gamma-linolenic acid, and long-chain n-3 fatty acids, respectively, on cardiovascular and renal responses to chronic (5 weeks) cyclosporine administration were studied in male borderli...

journal_title：Transplantation

authors： Mills DE,Ward RP,McCutcheon D,Dixon H,Ly H,Scholey J

更新日期：1992-03-01 00:00:00

abstract：:Islet transplantation is currently being explored as a treatment for patients with type 1 diabetes. At present, the number of patients becoming insulin-independent is rapidly increasing world-wide applying the transplantation protocol originally described by the group in Edmonton. A hallmark in this procedure is repea...

journal_title：Transplantation

authors： Korsgren O,Nilsson B,Berne C,Felldin M,Foss A,Kallen R,Lundgren T,Salmela K,Tibell A,Tufveson G

更新日期：2005-05-27 00:00:00

abstract：:Tolerogen-specific alloreactivity, in the form of mixed lymphocyte responses and cell mediated lympholysis, was measured in vitro using lymphocytes from mice that received neonatal inoculations of H-2 semiallogeneic hematopoietic cells. It was found that depletion of specific alloreactivity, as detected by these assay...

journal_title：Transplantation

authors： Streilein JW,Strome P,Wood PJ

更新日期：1989-10-01 00:00:00

abstract：:In three patients with end-stage renal failure due to primary hyperoxaluria type 1, successful combined liver-kidney transplantation enabled us to assess the insoluble oxalate pool, which was compared with the histopathological changes observed in iliac crest biopsy specimens. Good correlation was observed between the...

journal_title：Transplantation

authors： Toussaint C,Vienne A,De Pauw L,Gelin M,Janssen F,Hall M,Schurmans T,Pasteels JL

更新日期：1995-06-27 00:00:00

abstract：BACKGROUND:The present study was undertaken to determine whether anti-complement 5 (C5) monoclonal antibodies (mAb) prevent hyperacute rejection (HAR) in a rat-to-presensitized mouse heart transplantation model and whether these mAb, combined with cyclosporine (CsA) and cyclophosphamide (CyP), can achieve long-term gra...

journal_title：Transplantation

authors： Wang H,Rollins SA,Gao Z,Garcia B,Zhang Z,Xing J,Li L,Kellersmann R,Matis LA,Zhong R

更新日期：1999-12-15 00:00:00

abstract：BACKGROUND:The potential benefits of islet xenografting in type 1 diabetes include the intriguing, but still unanswered, possibility that the grafted xenoislets may be less subjected to human autoimmune attack. Cytokines may play a major role in the pathogenesis of autoimmune diabetes by causing impairment of insulin r...

journal_title：Transplantation

authors： Piro S,Lupi R,Dotta F,Patanè G,Rabuazzo MA,Marselli L,Santangelo C,Realacci M,Del Guerra S,Purrello F,Marchetti P

更新日期：2001-01-15 00:00:00

abstract：BACKGROUND:DBA/2J kidney allografts, but not heart allografts, are spontaneously accepted indefinitely in C57BL/6 (B6) mice, through regulatory tolerance mechanism dependent on Foxp3 cells. In contrast, B6 kidneys are rejected within a week in DBA/2J recipients. We hypothesized that the tolerogenic difference of the ki...

journal_title：Transplantation

authors： Oh NA,O'Shea T,Ndishabandi DK,Yuan Q,Hong S,Gans J,Ge J,Gibney S,Chase C,Yang C,Rosales I,Shinoda K,Drew B,Kojima L,Russell PS,Madsen JC,Colvin RB,Alessandrini A

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:To confirm the results of a number of studies conducted in Europe, the United States, and Japan, this multicenter, randomized trial compared the 12-month efficacy and safety of tacrolimus- and cyclosporine-based immunosuppressive regimens in the prevention of renal allograft rejection. METHODS:A total of 44...

journal_title：Transplantation

authors： Mayer AD,Dmitrewski J,Squifflet JP,Besse T,Grabensee B,Klein B,Eigler FW,Heemann U,Pichlmayr R,Behrend M,Vanrenterghem Y,Donck J,van Hooff J,Christiaans M,Morales JM,Andres A,Johnson RW,Short C,Buchholz B,Rehmert N

更新日期：1997-08-15 00:00:00

abstract：:Low-affinity, cold-reactive antibodies easily removed by washing were not detected by the antiglobulin technique but killed T lymphocytes when washing was omitted, incubation was prolonged, and cytotoxic tests were incubated at room temperature or at 4 degrees C. These antibodies were present in approximately 25% of s...

journal_title：Transplantation

authors： Pettaway CA,Freeman C,Helderman JH,Stastny P

更新日期：1987-10-01 00:00:00

abstract：BACKGROUND:A recent proposal supports the elimination of allocation points for human leukocyte antigen (HLA) mismatches (MM) in cadaveric kidney transplantation. The intent is to increase access for some racial groups that might be disadvantaged by the representation of race-specific HLA in a largely white donor pool. ...

journal_title：Transplantation

authors： Rebellato LM,Arnold AN,Bozik KM,Haisch CE

更新日期：2002-12-15 00:00:00

abstract：:The effect of cyclosporine and metabolite 17 (M17) as well as other CsA-related compounds (CsG, dihydro-CsC, dihydro-CsD, CsH, B5.49, and H7.94) was tested on T lymphocyte clone proliferation. In these experiments, antigen and interleukin 2 (IL-2) dependent long-term T lymphocyte clones derived from a rejected human k...

journal_title：Transplantation

authors： Chabannes D,Moreau JF,Soulillou JP

更新日期：1987-12-01 00:00:00

abstract：BACKGROUND:Human CD58 is an adhesion molecule that interacts with CD2 on lymphocytes. We describe here an antibody that blocks responses of human peripheral blood mononuclear cells (PBMCs) to porcine cells and reacts with a porcine protein with homology to CD58. METHODS:Antibodies were isolated with a screen for inhib...

journal_title：Transplantation

authors： Crosby K,Yatko C,Dersimonian H,Pan L,Edge AS

更新日期：2004-04-27 00:00:00

abstract：BACKGROUND:There are limited experimental data on the nature of the humoral response elicited in humans against pig antigens. In this study, we have examined the xenoantibody (XAb) response in eight patients with acute liver failure exposed to pig hepatocytes after treatment with the bioartificial liver (BAL). METHODS...

journal_title：Transplantation

authors： Baquerizo A,Mhoyan A,Kearns-Jonker M,Arnaout WS,Shackleton C,Busuttil RW,Demetriou AA,Cramer DV

更新日期：1999-01-15 00:00:00

abstract：BACKGROUND:One of the alternative options to simultaneous pancreas-kidney transplantation (SPKT) for type I diabetics with renal failure is sequential transplant of a living donor kidney followed by a deceased donor pancreas transplant (pancreas after living donor kidney transplant [PALK]). We retrospectively compared ...

journal_title：Transplantation

authors： Poommipanit N,Sampaio MS,Cho Y,Young B,Shah T,Pham PT,Wilkinson A,Danovitch G,Bunnapradist S

更新日期：2010-06-27 00:00:00

abstract：:Governmental and private programs that pay next of kin who give permission for the removal of their deceased relative's organs for transplantation exist in a number of countries. Such payments, which may be given to the relatives or paid directly for funeral expenses or hospital bills unrelated to being a donor, aim t...

journal_title：Transplantation

authors： Capron AM,Delmonico FL,Dominguez-Gil B,Martin DE,Danovitch GM,Chapman J

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:We investigated a novel immunosuppressive protocol including thymoglobulin induction in combination with sirolimus and corticosteroids, followed by introduction of markedly reduced exposures to cyclosporine to prevent pancreas-transplant rejection. METHODS:A 7-day course of thymoglobulin (1.5 mg/kg per day)...

journal_title：Transplantation

authors： Knight RJ,Kerman RH,Zela S,Podder H,Van Buren CT,Katz S,Kahan BD

更新日期：2003-04-27 00:00:00

abstract：:A role for cytomegalovirus (CMV) infection in the etiologies of acute and chronic rejection in renal allograft recipients has been suggested. We previously reported that preemptive treatment of CMV infection with ganciclovir in kidney transplant patients was safe and effective. We now present a retrospective analysis ...

journal_title：Transplantation

authors： Akposso K,Rondeau E,Haymann JP,Peraldi MN,Marlin C,Sraer JD

更新日期：1997-04-15 00:00:00

abstract：:Graft-versus-host disease is a potential problem following small bowel transplantation. We have previously shown that a two-day intraperitoneal course of polyclonal antilymphocyte serum completely prevents GVHD without impairing allograft function in a unidirectional rat small bowel transplant model. In the present st...

journal_title：Transplantation

authors： Shaffer D,Ubhi CS,Simpson MA,Gottschalk R,Milford EL,Maki T,Monaco AP

更新日期：1991-12-01 00:00:00

abstract：:Living organ donation is of increasing importance to satisfy the demand of good quality organs for patients remaining for extended periods on the waiting list. While the benefit for the recipient is undeniable, the organ procurement represents an important burden to live donors in terms of invasiveness and long-term c...

journal_title：Transplantation

authors： Horgan S,Galvani C,Gorodner V,Bareato U,Panaro F,Oberholzer J,Benedetti E

更新日期：2007-10-15 00:00:00

abstract：BACKGROUND:Despite the prevalent use of rabbit antithymocyte globulin (rATG) as an induction agent in kidney transplantation, the appropriate dose for preventing acute rejection in high-risk patients is not known. Few studies have examined total exposure of rATG less than 6 mg/kg, with fewer studies examining lower dos...

journal_title：Transplantation

authors： Klem P,Cooper JE,Weiss AS,Gralla J,Owen P,Chan L,Wiseman AC

更新日期：2009-10-15 00:00:00