Robotic distal pancreatectomy and nephrectomy for living donor pancreas-kidney transplantation.

abstract：BACKGROUND:Previous studies have shown that posttransplant total lymphoid irradiation, anti-thymocyte globulin, and an intravenous donor blood cell infusion induce tolerance to ACI heart allografts in Lewis rat hosts. METHODS:In the current study, fresh ACI monocytes and dendritic cell precursors, derived from short-t...

journal_title：Transplantation

authors： Hayamizu K,Huie P,Sibley RK,Strober S

更新日期：1998-11-27 00:00:00

abstract：BACKGROUND:It is well known that kidney transplant recipients with preformed lymphocytotoxic antibodies against HLA antigens have an increased graft rejection rate. However, the individual contribution of anti-HLA class I and class II antibodies to this phenomenon is poorly understood. We investigated the clinical rele...

journal_title：Transplantation

authors： Süsal C,Opelz G

更新日期：2002-04-27 00:00:00

abstract：:Natural killer (NK) lymphocytes are powerful effector cells of the peripheral immune system. NK cell functions are controlled by the expression of a variety of cell surface receptors with either inhibitory or activating roles. The genetic and functional diversity of this repertoire of receptors and the role of human l...

journal_title：Transplantation

authors： Young NT

更新日期：2004-07-15 00:00:00

abstract：:Cross sensitization between the products of the H-2K and H-2D loci has been demonstrated by an experimental design in which recipients were sensitized with tissue bearing determinants controlled by one locus (e.g., H-2K), and then challenged with skin grafts expressing determinants controlled by the other locus (e.g.,...

journal_title：Transplantation

authors： Murphy DB,Shreffler DC

更新日期：1975-07-01 00:00:00

abstract：BACKGROUND:Although longer pretransplant dialysis has been associated with poor kidney transplant outcome, no data about this association exist from the current era or from Europe. We studied the association of pretransplant dialysis duration on outcomes after kidney transplantation across two different time periods. ...

journal_title：Transplantation

authors： Helanterä I,Salmela K,Kyllönen L,Koskinen P,Grönhagen-Riska C,Finne P

更新日期：2014-08-27 00:00:00

abstract：:Orthotopic liver allografts from BN donors to LEW recipients are spontaneously accepted, and the recipients develop donor-specific immunological unresponsiveness. This unresponsiveness may be mediated by suppressor T cells. Immunomagnetically purified splenic T cells from LEW rats bearing BN liver grafts were shown to...

journal_title：Transplantation

authors： Gassel HJ,Hutchinson IV,Engemann R,Morris PJ

更新日期：1992-12-01 00:00:00

abstract：:Fetal liver cells (FLC) were obtained from beagle fetuses 52 days postconception, and were cryopreserved prior to transplantation into ten sibling recipients that had previously been exposed to total-body irradiation delivered in 3 fractions of 6 Gy each at 4 days, 2 days, and 2 hr before grafting. Donors and hosts we...

journal_title：Transplantation

authors： Prümmer O,Raghavachar A,Werner C,Calvo W,Carbonell F,Steinbach I,Fliedner TM

更新日期：1985-04-01 00:00:00

abstract：BACKGROUND:Previous studies have identified more morbidity in simultaneous pancreas-kidney (SPK) transplant recipients compared with kidney alone (KA) recipients. With the development of novel immunosuppressive drugs, studies are needed to determine optimal treatment regimens in specific patient populations. METHODS:W...

journal_title：Transplantation

authors： Lee CM,Scandling JD,Krieger NR,Dafoe DC,Alfrey EJ

更新日期：1997-11-15 00:00:00

abstract：BACKGROUND:Recent advances in the understanding of immunomodulatory properties of phosphodiesterase 4 (PDE4) inhibitors recommend these drugs for immunosuppressive therapy after lung transplantation. The potency of three PDE4 inhibitors was tested using an established model of heterotopic tracheal transplantation in ra...

journal_title：Transplantation

authors： Schade I,Roth-Eichhorn S,Kasper M,Kuss H,Plötze K,Funk RH,Schüler S

更新日期：2002-08-15 00:00:00

abstract：:Hematopoietic growth factors (HGF) mobilize potential tolerogenic cells in transplant donors. Fms-like tyrosine kinase 3 ligand (Flt3L) mobilizes stem cells and dendritic cells (DCs) in human and nonhuman primate blood. Blood and renal and liver biopsies were obtained from untreated and Flt3L-mobilized rhesus macaques...

journal_title：Transplantation

authors： Morelli AE,Coates PT,Shufesky WJ,Barratt-Boyes SM,Fung JJ,Demetris AJ,Thomson AW

更新日期：2007-03-15 00:00:00

abstract：:Although the requirements for the induction of IL-2 receptor expression following lymphocyte stimulation in vitro have been well characterized, little information is available on the role of IL-2 and the IL-2 receptor in lymphocyte activation in vivo. We have established a quantitative assay for the measurement of IL-...

journal_title：Transplantation

authors： Kroczek RA,Black CD,Barbet J,Edison LJ,Shevach EM

更新日期：1987-10-01 00:00:00

abstract：:There is substantial evidence that increased cellular calcium may activate processes that lead to cellular injury and death, and calcium entry blockers (CEB) have been shown to protect against renal ischemic injury. This approach has been used experimentally to enhance kidney preservation during both warm and cold isc...

journal_title：Transplantation

authors： Nakamoto M,Shapiro JI,Mills SD,Schrier RW,Chan L

更新日期：1988-02-01 00:00:00

abstract：:Humoral or antibody-mediated rejection in cardiac transplant recipients is mediated by donor-specific cytotoxic antibodies and is histologically defined by linear deposits of immunoglobulin and complement in the myocardial capillaries. Antibody-mediated rejection often is accompanied by hemodynamic compromise and is a...

journal_title：Transplantation

authors： Aranda JM Jr,Scornik JC,Normann SJ,Lottenberg R,Schofield RS,Pauly DF,Miles M,Hill JA,Sleasman JW,Skoda-Smith S

更新日期：2002-03-27 00:00:00

abstract：BACKGROUND:Dendritic cells (DC) are important in the development of acute graft-versus-host disease (GVHD) after allogeneic hemopoietic cell transplantation (alloHCT). The trafficking of immature DC from blood to GVHD target organs is likely to be regulated by chemokine receptors. METHODS:We performed flow cytometry t...

journal_title：Transplantation

authors： Shahin K,Sartor M,Hart DN,Bradstock KF

更新日期：2013-10-27 00:00:00

abstract：BACKGROUND:Osteoporosis is a well-documented complication of organ transplantation. Bisphosphonates have been shown to be effective in preventing corticosteroid-induced osteoporosis in renal transplant recipients, but data are lacking for treatment of established osteoporosis. This study reports our clinical experience...

journal_title：Transplantation

authors： Arlen DJ,Lambert K,Ioannidis G,Adachi JD

更新日期：2001-03-15 00:00:00

abstract：:Tacrolimus (FK) and cyclosporine (Cs) are potent immunosuppressants that effectively prevent the rejection of transplanted organs including liver and small intestine. Our study examined the effects of these immunosuppressants on Peyer's patches, which play an important role in mucosal immune response through uptake an...

journal_title：Transplantation

authors： Fujimura Y,Owen RL

更新日期：2002-04-15 00:00:00

abstract：BACKGROUND:The quantitation of donor leukocyte chimerism may aid in establishing the etiology of neutropenia after liver transplantation. METHODS:The incidence and clinical and laboratory characteristics of severe neutropenia were studied in adults who have undergone liver transplantation at our institution over the l...

journal_title：Transplantation

authors： Jonsson JR,Gill D,Hogan PG,Clouston AD,Edwards-Smith C,Griffin AD,Balderson GA,Lynch SV,Strong RW,Powell EE

更新日期：1999-05-27 00:00:00

abstract：:The frequency of donor-reactive and of third party-reactive cytotoxic T lymphocyte precursors (CTLp) was determined by limiting dilution analysis in the peripheral blood of 13 liver allograft recipients before (pre-tpx) and at various intervals (4 to 22 months) after (post-tpx) transplantation. In 6 of 13 patients wit...

journal_title：Transplantation

authors： Eberspächer ML,Otto G,Herfarth C,Kabelitz D

更新日期：1994-06-27 00:00:00

abstract：:The United Network for Organ Sharing is poised to resolve geographic disparity in liver transplantation and promote allocation based on medical urgency. At the time of writing, United Network for Organ Sharing is considering redistricting the organ procurement and transplantation network so that patient model for end-...

journal_title：Transplantation

authors： Mehrotra S,Kilambi V,Gilroy R,Ladner DP,Klintmalm GB,Kaplan B

更新日期：2015-02-01 00:00:00

abstract：:Despite great improvements in renal allograft survival over the last 3 decades, long-term graft loss, particularly through antibody-mediated rejection, remains the bane of kidney transplantation. Interindividual patient variation means that a given immunosuppressive regimen may be inadequate in certain patients and ex...

journal_title：Transplantation

authors： Ashton-Chess J,Giral M,Soulillou JP,Brouard S

更新日期：2009-05-15 00:00:00

abstract：BACKGROUND:As T-cell receptor-major histocompatibility complex (MHC) class I/self peptide interaction regulates T-cell development in the thymus, we reasoned that presentation of peptides by self dendritic cells (DC) to developing T cells in the thymus might induce acquired thymic tolerance. This hypothesis is based on...

journal_title：Transplantation

authors： Ali A,Garrovillo M,Jin MX,Hardy MA,Oluwole SF

更新日期：2000-01-27 00:00:00

abstract：:BK polyoma virus causes allograft dysfunction as a result of tubulo-interstitial nephritis in 2% to 5% of renal transplant recipients. The incidence of BK virus infection among renal transplant recipients in India is unknown. We used routine histologic examination, immunohistochemistry, and electron microscopy to retr...

journal_title：Transplantation

authors： Sachdeva MS,Nada R,Jha V,Sakhuja V,Joshi K

更新日期：2004-02-15 00:00:00

abstract：:The concept of islet exhaustion maintains that exposure of pancreatic islets to hyperglycemia and other stresses leads to islet dysfunction and irreparable damage. The process of pancreatic transplantation places many stresses on islets (e.g., counter-regulatory hormones, steroids, cyclosporine toxicity). As practiced...

journal_title：Transplantation

authors： Dafoe DC,Campbell DA Jr,Rosenberg L,Merion RM,Ucros I,Vinik AI,Klandorf H,Turcotte JG

更新日期：1989-07-01 00:00:00

abstract：:Rabbit antisera to rat thoracic duct lymphocytes were examined by absorption analysis with quantitative radioimmunoassays to determine the tissue distribution of the antigens recognised and the amount of antibody against different specificities. Seven of eight sera were remarkably specific for leucocytes and one serum...

journal_title：Transplantation

authors： Fabre JW,Williams AF

更新日期：1977-04-01 00:00:00

abstract：BACKGROUND:In recent years, transplantation of islets and pancreas has become a viable option for patients debilitated with type I diabetes. The success of islet transplantation has been attributed to the ability to isolate high quality islets for transplantation and capacity to maintain the recipient's immunosuppressi...

journal_title：Transplantation

authors： Mohanakumar T,Narayanan K,Desai N,Ramachandran S,Shenoy S,Jendrisak M,Susskind BM,Olack B,Benshoff N,Phelan DL,Brennan DC,Fernandez LA,Odorico JS,Polonsky KS

更新日期：2006-07-27 00:00:00

abstract：:Chronic pulmonary disease is associated with varying degrees of cardiac dysfunction. Because of the potentially predominant effect of severe lung disease on right ventricular (RV) size and function, a reliable method to assess RV mechanics before and after lung transplantation may provide information of long-term sign...

journal_title：Transplantation

authors： Vigneswaran WT,McDougall JC,Olson LJ,Breen JF,McGregor CG,Rumberger JA

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND:As opposed to most solid-organ transplant recipients, patients with acute liver failure exhibit a pretransplant health status more comparable with the general population, and any posttransplant cardiovascular risk excess should thus be more attributable to transplantation-related factors alone. METHODS:This...

journal_title：Transplantation

authors： Aberg F,Jula A,Höckerstedt K,Isoniemi H

更新日期：2010-01-15 00:00:00

abstract：BACKGROUND:Our aim was to evaluate the effect of FTY720 in discordant islet xenotransplantation. METHODS:Fetal porcine islet-like cell clusters (ICCs) were transplanted into normoglycemic rats that were either left untreated or treated with FTY720 only, with FTY720 plus cyclosporine A (CsA) or with CsA only. Twelve or...

journal_title：Transplantation

authors： Maeda A,Goto M,Zhang J,Bennet W,Groth CG,Korsgren O,Wennberg L

更新日期：2003-04-27 00:00:00

abstract：BACKGROUND:We evaluated the importance and mechanism of graft and host accommodation in hamster-to-rat cardiac xenotransplantation models. METHODS:To evaluate graft accommodation, accommodated hamster grafts (Group 2) were transplanted to naïve host rats treated with FK506, and compared with naïve hamster grafts (Grou...

journal_title：Transplantation

authors： Komori K,Fuchimoto Y,Morikawa Y,Obara H,Kawachi S,Tanabe M,Hoshino K,Shimazu M,Matsuzaki Y,Kitajima M

更新日期：2008-01-15 00:00:00

abstract：BACKGROUND:Immunosuppression involves the nature of the immunosuppressive agents and individual differences in patient factors. We investigated whether the effect of mycophenolate mofetil (MMF) is measurable using an in vitro measure of immunocompetence and related its effects to cyclosporine (CsA) in vitro. METHODS:L...

journal_title：Transplantation

authors： Ogawa N,Nagashima N,Nakamura M,Shalabi A,Maley WR,Burdick JF

更新日期：2001-08-15 00:00:00