Cross reactivity between H-2K and H-2D products. III. Effect of H-2K-H-2D cross sensitization on skin graft survival.

abstract：BACKGROUND:Kidney grafts with multiple renal arteries have been considered a relative contraindication because of the increased risk of complications. In the present study, we retrospectively reviewed multiple renal artery reconstruction in kidney transplantation to elucidate the usefulness of these grafts. METHODS:Fr...

journal_title：Transplantation

authors： Makiyama K,Tanabe K,Ishida H,Tokumoto T,Shimmura H,Omoto K,Toma H

更新日期：2003-03-27 00:00:00

abstract：BACKGROUND:Donor pigs transgenic for human decay-accelerating factor (hDAF) were used in a xenogeneic ex vivo liver perfusion model to study the effect of this modification on the development of hyperacute rejection. METHODS:Three transgenic pigs were hepatectomized after hypothermic portal and transaortal gravity per...

journal_title：Transplantation

authors： Pascher A,Poehlein C,Storck M,Prestel R,Mueller-Hoecker J,White DJ,Abendroth D,Hammer C

更新日期：1997-08-15 00:00:00

abstract：:Pregnancy in inbred mice is associated with long-term accceptance of H-Y-incompatible skin grafts (in some "rejector" strain females) and with the formation of cytotoxic and agglutinating H-Y antibodies (in females generally). Yet there is no evident correlation between the two phenomena; postpartum females of nonreje...

journal_title：Transplantation

authors： Krupen-Brown K,Wachtel SS

更新日期：1979-06-01 00:00:00

abstract：BACKGROUND:This study aimed at investigating the efficacy of the novel immunosuppressant FK778 to prevent the development and progression of chronic allograft vasculopathy (CAV). METHODS:Orthotopic aortic transplantations were performed in the PVG-to-ACI rat model and followed over the course of 120 days. Immunosuppre...

journal_title：Transplantation

authors： Deuse T,Hoyt G,Koyanagi T,Robbins RC,Schrepfer S

更新日期：2008-03-27 00:00:00

abstract：BACKGROUND:The National Marrow Donor Program (NMDP) has approximately 5 million registered potential donors and continues to add more than 30,000 new recruits to the registry monthly. However, more than 30% of potential donors are not available or decline to donate at key decision points in the donation process. Althou...

journal_title：Transplantation

authors： Myaskovsky L,Switzer GE,Dew MA,Goycoolea JM,Confer DL,Abress L

更新日期：2004-03-27 00:00:00

abstract：BACKGROUND:The use of urine flow cytometry (UFC) as a noninvasive tool for the diagnosis of acute and chronic rejection of the renal allograft has been previously reported. METHODS:We analyzed the expression of various cell surface antigens during a 30-day period after the diagnosis and treatment of 24 acute rejection...

journal_title：Transplantation

authors： Roberti I,Reisman L

更新日期：2001-05-15 00:00:00

abstract：:Erythropoietin (EPO) is widely used among patients with end-stage renal disease awaiting transplantation. Data suggest that EPO therapy may be immunomodulatory. The purpose of this study was to assess the effects of pretransplant EPO therapy on renal allograft outcome. We evaluated 120 consecutive renal transplant rec...

journal_title：Transplantation

authors： Vasquez EM,Pollak R

更新日期：1996-10-15 00:00:00

abstract：:The glycosaminoglycan hyaluronan is not only involved in cellular differentiation and migration but may also play a role in several inflammatory diseases. We have previously demonstrated an increased local production of hyaluronan in chronically rejected kidneys and the correspondingly affected renal vessels. In this ...

journal_title：Transplantation

authors： Wells A,Larsson E,Hanás E,Laurent T,Hällgren R,Tufveson G

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:The potential risk of transmission of porcine endogenous retroviruses (PERV) from xenogeneic donors into humans has been widely debated. Because we were involved in a phase I/II clinical trial using a bioartificial liver support system (BLSS), we proceeded to evaluate the biosafety of this device. MATERIALS...

journal_title：Transplantation

authors： Kuddus R,Patzer JF 2nd,Lopez R,Mazariegos GV,Meighen B,Kramer DJ,Rao AS

更新日期：2002-02-15 00:00:00

abstract：:As a consequence of its large volume, a microencapsulated islet graft can be implanted only into the peritoneal cavity. The graft volume can be reduced by using small capsules. However, reduction of the diameter of the capsules holds a certain risk, because with smaller capsules, more islets may be found to protrude f...

journal_title：Transplantation

authors： De Vos P,De Haan B,Pater J,Van Schilfgaarde R

更新日期：1996-10-15 00:00:00

abstract：BACKGROUND:De novo donor HLA-specific (dnDSA) and non-HLA antibodies including antiangiotensin type 1 receptor antibodies (AT1R-abs) have been associated with antibody-mediated rejection (AMR) and decreased graft survival as well as cellular-mediated rejection (CMR) and early onset of microvasculopathy in heart transpl...

journal_title：Transplantation

authors： Reinsmoen NL,Lai CH,Mirocha J,Cao K,Ong G,Naim M,Wang Q,Haas M,Rafiei M,Czer L,Patel J,Kobashigawa J

更新日期：2014-03-15 00:00:00

abstract：:Living-donor liver transplantation has provided a solution to the severe lack of cadaveric grafts for the replacement of livers afflicted with end-stage cirrhosis, fulminant disease, or inborn errors of metabolism. The pioneering experience in Japan in the early 1990s helped open wide the avenues of a new branch of sc...

journal_title：Transplantation

authors： Chen CL,Fan ST,Lee SG,Makuuchi M,Tanaka K

更新日期：2003-02-15 00:00:00

abstract：BACKGROUND:Connective tissue growth factor (CTGF) is a key mediator of tissue fibrogenesis in kidney disease. Its involvement in renal allograft fibrosis was recently demonstrated in a mouse model. METHODS:We prospectively studied the association between urinary CTGF (CTGFu) levels and renal allograft fibrosis during ...

journal_title：Transplantation

authors： Metalidis C,van Vuuren SH,Broekhuizen R,Lerut E,Naesens M,Bakker SJ,Wetzels JF,Goldschmeding R,Kuypers DR

更新日期：2013-09-15 00:00:00

abstract：BACKGROUND:Vascular endothelial growth factor (VEGF) is a potent endothelial cell growth and permeability factor, expressed in the lung. Overexpression of VEGF is associated with increased vascular permeability in the early stage of acute lung injury in mice. The role of various forms of VEGF in transplantation-induced...

journal_title：Transplantation

authors： Abraham D,Taghavi S,Riml P,Paulus P,Hofmann M,Baumann C,Kocher A,Klepetko W,Aharinejad S

更新日期：2002-06-15 00:00:00

abstract：:A controlled trial was carried out to assess the value of intensive plasma exchange in 27 renal transplant recipients with clinical and histological evidence of acute vascular rejection. In addition to standard immunosuppression, 13 patients received plasma exchange on six consecutive days at a mean exchange volume of...

journal_title：Transplantation

authors： Allen NH,Dyer P,Geoghegan T,Harris K,Lee HA,Slapak M

更新日期：1983-05-01 00:00:00

abstract：:Despite major advances in immunopharmacology, virtually all patients receive the same center-specific immunosuppressive regimen following orthotopic liver transplantation (OLT). The present analysis was performed on the hypothesis that the original disease representing the indication for OLT leads to a different initi...

journal_title：Transplantation

authors： Berlakovich GA,Imhof M,Karner-Hanusch J,Gotzinger P,Gollackner B,Gnant M,Hanelt S,Laufer G,Muhlbacher F,Steininger R

更新日期：1996-02-27 00:00:00

abstract：:To improve long-term outcome after renal transplantation, attention should be placed on the tailored use of immunosuppressive regimens that have a more favorable impact on the immunological and nonimmunological risk profiles of an individual recipient. Tacrolimus is widely used for maintenance and rejection immunosupp...

journal_title：Transplantation

authors： First MR

更新日期：2001-09-27 00:00:00

abstract：BACKGROUND:Preconditioning protects against both liver and lung damage after hepatic ischemia-reperfusion (I/R). Xanthine and xanthine oxidase (XOD) may contribute to the development of hepatic I/R. OBJECTIVE:To evaluate whether preconditioning could modulate the injurious effects of xanthine/XOD on the liver and lung...

journal_title：Transplantation

authors： Peralta C,Bulbena O,Xaus C,Prats N,Cutrin JC,Poli G,Gelpi E,Roselló-Catafau J

更新日期：2002-04-27 00:00:00

abstract：:Seventy-two dog kidneys were stored under hypothermia as described by Collins and Sacks between 24 and 72 hr and then transplanted. The immediate function of the kidneys was measured by p-aminohippuric acid and inulin clearances. Twenty-four hr proved to be the maximum safe preservation time with both methods. The imm...

journal_title：Transplantation

authors： Grundmann R,Strümper R,Eichmann J,Pichlmaier H

更新日期：1977-05-01 00:00:00

abstract：BACKGROUND:At present, autologous intestinal segments are often used for bladder reconstruction. However, the gastrointestinal mucosa often causes various complications. METHODS:Oral mucosal tissues were obtained from the buccal cavity of beagle dogs. Primary oral mucosal epithelial cells were cultured on temperature-...

journal_title：Transplantation

authors： Watanabe E,Yamato M,Shiroyanagi Y,Tanabe K,Okano T

更新日期：2011-04-15 00:00:00

abstract：:We report on the to date largest recovery of 11 organs from a single deceased donor with the transplantation of face, bilateral upper extremities, heart, 1 lung, liver (split for 2 recipients), kidneys, pancreas, and intestine. Although logistically challenging, this case demonstrates the feasibility and safety of the...

journal_title：Transplantation

authors： Tullius SG,Pomahac B,Kim HB,Carty MJ,Talbot SG,Nelson HM,Delmonico FL

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Success of human pancreatic islet isolation depends largely on the techniques used during pancreas procurement and the quality of the gland. Warm ischemia of the pancreas of any duration during organ procurement may be detrimental to subsequent islet yield and functional viability of the islets. The aim of t...

journal_title：Transplantation

authors： Lakey JR,Kneteman NM,Rajotte RV,Wu DC,Bigam D,Shapiro AM

更新日期：2002-04-15 00:00:00

abstract：:A cluster of five cases of Legionnaires' disease in renal transplant patients is described. They were treated with erythromycin and rifampicin, and all five survived. Two of them had rejected their grafts prior to their Legionella pneumonia; two rejected their transplants after reduction of immunosuppressive therapy t...

journal_title：Transplantation

authors： Wilczek H,Kallings I,Nyström B,Hoffner S

更新日期：1987-06-01 00:00:00

abstract：BACKGROUND:The polymorphic family of killer-cell immunoglobulin-like receptors (KIRs) consists of activating and inhibitory receptors expressed by natural killer (NK) cells and effector T cells that recognize human leukocyte antigen (HLA) class I ligands. It has been suggested that KIR/HLA incompatibility exerts benefi...

journal_title：Transplantation

authors： Kunert K,Seiler M,Mashreghi MF,Klippert K,Schönemann C,Neumann K,Pratschke J,Reinke P,Volk HD,Kotsch K

更新日期：2007-12-15 00:00:00

abstract：:We studied the reactivity of cardiac graft-infiltrating cells, cultured from endomyocardial biopsy specimens, toward heart endothelial cells (Hec). In two cases, Hec derived from the specific donor heart or Hec compatible with the donor were lysed, but not the syngeneic B cell line. A vessel-derived endothelial cell l...

journal_title：Transplantation

authors： Jutte NH,Knoop CJ,Heijse P,Balk AH,Mochtar B,Claas FH,Weimar W

更新日期：1996-08-15 00:00:00

abstract：:We have tested the predictive model for risk of sensitization by donor-specific transfusions developed at the University of California, San Francisco for its applicability to the DST experience at UW/Madison. Patient sample sizes between the two groups were similar (n = 249 for UW/Madison, n = 261 for UCSF) and the tw...

journal_title：Transplantation

authors： Burlingham WJ,Stratta R,Mason B,Lorentzen D,Feyzi J,Sollinger HW,Belzer FO

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) reinfection of the liver allograft after transplantation is universal, with some individuals suffering severe disease recurrence. Predictive markers of recurrent disease severity are urgently needed. In this study, we used a cluster of differentiation (CD) microarray to predict the se...

journal_title：Transplantation

authors： Rahman W,Tu T,Budzinska M,Huang P,Belov L,Chrisp JS,Christopherson RI,Warner FJ,Bowden DS,Thompson AJ,Bowen DG,Strasser SI,Koorey D,Sharland AF,Yang JY,McCaughan GW,Shackel NA

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Although proportionally more veterans live in rural areas compared to nonveterans, the impact of rurality status on kidney transplantation (KTP) access among veterans is unknown. Our objective was to study KTP rates among veterans listed for KTP and to compare the impact of rurality status on KTP rates among...

journal_title：Transplantation

authors： O'Shea AMJ,Franciscus CL,Kaboli PJ,Kalil RS

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:ABO-incompatible (ABOi) and positive crossmatch (XM) renal transplants pose special immunologic challenges. It is important to compare outcomes, study resource utilization, and attempt to risk stratify patients in these higher risk transplant settings. METHODS:We compared apheresis utilization and transplan...

journal_title：Transplantation

authors： Padmanabhan A,Ratner LE,Jhang JS,Duong JK,Markowitz GS,Vasilescu ER,Crew RJ,Schwartz J

更新日期：2009-06-27 00:00:00

abstract：:There is considerable current interest in the possibility that long-term graft acceptance in clinical solid-organ transplantation might be dependent upon the development of a microchimeric state between the donor and recipient. This possibility has been prompted by the observation that in some transplant patients cell...

journal_title：Transplantation

authors： Bushell A,Pearson TC,Morris PJ,Wood KJ

更新日期：1995-05-27 00:00:00