Effect of pretransplant erythropoietin therapy on renal allograft outcome.

abstract：:A monoclonal anti-Lyt-1.1 serum has been characterized in terms of its effect on various cell populations involved in cell-mediated immune responses. The monoclonal serum was compared to a conventionally prepared anti-Lyt-1.1 serum. Cytotoxic T cell precursors and effectors were found to be Lyt-1.1+. Helper T cells wh...

journal_title：Transplantation

authors： Shaw J,Pilarski LM,Al Adra AR,Leigh JB,Wilkins J,Hogarth PM,McKenzie IF,Paetkau V

更新日期：1981-01-01 00:00:00

abstract：INTRODUCTION:Some Indoasian (IA) patients with established renal failure travel abroad for commercial kidney transplantation. We compared the 1-year outcomes of IA patients from one UK region who received overseas transplants with IA patients receiving local living donor (LD) kidney transplantation, deceased donor (DD)...

journal_title：Transplantation

authors： Krishnan N,Cockwell P,Devulapally P,Gerber B,Hanvesakul R,Higgins R,Ready A,Carmichael P,Tomlinson K,Kumar S,Baharani J,Dasgupta I

更新日期：2010-06-27 00:00:00

abstract：:Sequential titers of five different humoral antibodies (antirat erythrocyte, antisheep erythrocyte, isoantibodies, rheumatoid factors, and serum agglutinators) were simultaneously performed on 20 patients with renal transplants, 12 patients with skin transplants, and 2 patient populations (one hospitalized and one amb...

journal_title：Transplantation

authors： Waller M,Pierce JC,Lee HM,Levinson HJ

更新日期：1975-03-01 00:00:00

abstract：BACKGROUND:Steroid-resistant acute rejection is a risk factor for inferior renal allograft outcome. METHODS:From 873 kidney transplant recipients (1995-2005), 108 patients with a first rejection episode were selected for study using strict inclusion criteria and clinical endpoint definition. We aimed to predict respon...

journal_title：Transplantation

authors： Rekers NV,Bajema IM,Mallat MJ,Zuidwijk K,Anholts JD,Goemaere N,Haasnoot GW,van Groningen MC,van Kooten C,de Fijter JW,Claas FH,Eikmans M

更新日期：2012-09-27 00:00:00

abstract：BACKGROUND:In 2013, the public health service (PHS) changed the criteria intended to identify organ donors that put the associated organ recipients at increased risk for acquiring human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV). The changing donor demographics, organ utilization...

journal_title：Transplantation

authors： Pruett TL,Clark MA,Taranto SE

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Systemic inflammation markers, such as neutrophil-to-lymphocyte ratio (NLR), have recently emerged as the prognostic factors for recurrence of liver tumors. METHODS:We assessed the ability of NLR and of other variables to predict the outcomes of orthotopic liver transplantation (OLT) for hepatocellular carc...

journal_title：Transplantation

authors： Bertuzzo VR,Cescon M,Ravaioli M,Grazi GL,Ercolani G,Del Gaudio M,Cucchetti A,D'Errico-Grigioni A,Golfieri R,Pinna AD

更新日期：2011-06-15 00:00:00

abstract：BACKGROUND:Our objective was to evaluate graft equilibration with high viscosity (University of Wisconsin solution [UW]) or low viscosity (Bretschneider's histidine-tryptophan-ketoglutarate [HTK]) during liver procurement from non-heart beating donors (NHBD) and the potential impact of a preceding fibrinolysis with str...

journal_title：Transplantation

authors： Minor T,Hachenberg A,Tolba R,Pauleit D,Akbar S

更新日期：2001-06-27 00:00:00

abstract：BACKGROUND:One of the earliest prerequisites for the development of inflammation after ischemia-reperfusion (I/R) is local chemokine expression. We recently demonstrated that apoptosis, characterized by intracellular caspase-activation, contributes to the development of inflammation after I/R. METHODS:The contribution...

journal_title：Transplantation

authors： Daemen MA,de Vries B,van't Veer C,Wolfs TG,Buurman WA

更新日期：2001-04-15 00:00:00

abstract：BACKGROUND:The majority of chronic hepatitis is ascribable to hepatitis C virus (HCV) infection, whereas the clinical impact has not been understood in kidney transplant recipients. Our current study was carried out to assess the impact of HCV infection on kidney recipients over the long-term, and to investigate the ef...

journal_title：Transplantation

authors： Hanafusa T,Ichikawa Y,Kishikawa H,Kyo M,Fukunishi T,Kokado Y,Okuyama A,Shinji Y,Nagano S

更新日期：1998-08-27 00:00:00

abstract：:The effect of protein depletion on immune responsiveness was examined using a skin allograft model. Protein depletion was induced in adult Fischer (F344) male rats by the ad libitum provision of a 5% protein diet. Total serum protein, total body weight, total body nitrogen, and total body lipid were all markedly decre...

journal_title：Transplantation

authors： Austin EH,Brennan MF,Rosenberg SA

更新日期：1980-09-01 00:00:00

abstract：:In organ transplantation, blood borne cells and macromolecules (e.g., antibodies) of the host immune system are brought into direct contact with the endothelial cell lining of graft vessels. In this location, graft endothelial cells play several roles in allograft rejection, including the initiation of rejection respo...

journal_title：Transplantation

authors： Al-Lamki RS,Bradley JR,Pober JS

更新日期：2008-11-27 00:00:00

abstract：:If ABO antigens/antibodies play any role in the pathogenesis of acute graft-versus-host disease (GVHD), one would expect the highest incidence of GVHD in recipients of minor ABO-mismatched grafts, followed by ABO-matched grafts, and the lowest incidence in major ABO-mismatched transplants. To test this hypothesis 174 ...

journal_title：Transplantation

authors： Bacigalupo A,Van Lint MT,Occhini D,Margiocco M,Ferrari G,Pittaluga PA,Frassoni F,Peralvo J,Lercari G,Carubia F

更新日期：1988-06-01 00:00:00

abstract：BACKGROUND:This study evaluates whether surgical strategies such as the portosystemic shunt and ischemic preconditioning can protect against hepatic and pulmonary injury associated with liver transplantation. METHODS:The effect of the portosystemic shunt, ischemic preconditioning, and both surgical procedures together...

journal_title：Transplantation

authors： Fernández L,Heredia N,Peralta C,Xaus C,Roselló-Catafau J,Rimola A,Marco A,Serafín A,Deulofeu R,Gelpí E,Grande L

更新日期：2003-07-27 00:00:00

abstract：BACKGROUND:Host macrophages are abundant within fetal pig pancreas xenografts undergoing rejection, but their role is unknown. Therefore, we examined the effect of host macrophage depletion on xenograft rejection. METHODS:Nonobese diabetic (NOD) mice were given clodronate-loaded liposomes intravenously to deplete macr...

journal_title：Transplantation

authors： Fox A,Koulmanda M,Mandel TE,van Rooijen N,Harrison LC

更新日期：1998-12-15 00:00:00

abstract：BACKGROUND:Matrix metalloproteinases (MMPs) play a key role in extracellular matrix remodeling events associated with hepatic regeneration after partial hepatectomy. We therefore hypothesized that urinary MMPs and their endogenous tissue inhibitors of matrix metalloproteinases (TIMPs) might also provide important infor...

journal_title：Transplantation

authors： Greene AK,Puder M,Roy R,Kilroy S,Louis G,Folkman J,Moses MA

更新日期：2004-10-27 00:00:00

abstract：:The immunosuppressive potentials of mAbs to lymphocyte function-associated antigen-1 (LFA-1) and CD2 molecules were examined in murine islet transplantation. Crude digested islets from BALB/c (H-2d) mice were transplanted into the renal subcapsular space of streptozotocin-induced diabetic C57BL/6 (H-2b) mice. The rat ...

journal_title：Transplantation

authors： Gotoh M,Fukuzaki T,Monden M,Dono K,Kanai T,Yagita H,Okumura K,Mori T

更新日期：1994-01-01 00:00:00

abstract：:Graft-versus-host disease is a potential problem following small bowel transplantation. We have previously shown that a two-day intraperitoneal course of polyclonal antilymphocyte serum completely prevents GVHD without impairing allograft function in a unidirectional rat small bowel transplant model. In the present st...

journal_title：Transplantation

authors： Shaffer D,Ubhi CS,Simpson MA,Gottschalk R,Milford EL,Maki T,Monaco AP

更新日期：1991-12-01 00:00:00

abstract：:A novel, water-soluble metabolite of cyclosporine, a sulphate conjugate, present in high concentrations in human bile and plasma was evaluated for its immunosuppressive properties. The direct binding of the conjugate to surface molecules on lymphocytes was studied. The effect of the metabolite was tested in several in...

journal_title：Transplantation

authors： Johansson A,Henricsson S,Möller E

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:Insults to the airway epithelium play a key role in constrictive bronchiolitis after lung transplantation, the typical hallmark of chronic rejection. Our hypothesis is that immunosuppressives might affect airway integrity. METHODS:A biculture of human bronchial epithelial cells and lung microvascular endoth...

journal_title：Transplantation

authors： Bellon H,Vandermeulen E,Verleden SE,Heigl T,Vriens H,Lammertyn E,Verlinden L,Vanhove T,Verstuyf M,Hoet P,Vos R,Verleden GM,Vanaudenaerde BM

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:In live donor liver transplantation portal flush only of the graft is done on the bench. There are no data on antegrade arterial flush along with portal flush of the graft. METHODS:Consecutive patients undergoing elective right lobe live donor liver transplantation were block-randomized to receive either po...

journal_title：Transplantation

authors： Pamecha V,Sandhyav R,Sinha PK,Bharathy KGS,Sasturkar S

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Since suitable recipients for hepatic allografts from donors with antibodies to hepatitis B virus (HBV) have not been determined, a review of our 7-year experience with donors positive for hepatitis B surface antibody (anti-HBs), hepatitis B core antibody (anti-HBc), or both was undertaken. METHODS:Recipien...

journal_title：Transplantation

authors： Dodson SF,Issa S,Araya V,Gayowski T,Pinna A,Eghtesad B,Iwatsuki S,Montalvo E,Rakela J,Fung JJ

更新日期：1997-12-15 00:00:00

abstract：:Although ELISA on purified HLA molecules for detecting anti-HLA antibody (P-S ELISA) does detect some antibodies previously missed by the conventional complement dependent cytotoxicity method (C Cytotox), HLA ELISA should not fail to detect antibodies already detected by the conventional reference method to be able to...

journal_title：Transplantation

authors： Pierquin A,Masson D,Toupance O,Tabary T,Bougy F,Bensa JC,Chanard J,Cohen JH

更新日期：1996-11-27 00:00:00

abstract：:Among the first 52 recipients of primary liver allografts with follow-up of 2 weeks or greater, 6 patients had biopsy-confirmed vanishing bile duct syndrome (VBDS) and required retransplantation. Five of these six patients had positive lymphocyte crossmatches. Of the 46 remaining liver transplant recipients, 11 had po...

journal_title：Transplantation

authors： Batts KP,Moore SB,Perkins JD,Wiesner RH,Grambsch PM,Krom RA

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND:The functional relevance of HLA-C mismatches in an alloresponse is still much debated, putting into doubt the relevance of matching for this antigen in selection of an allogeneic bone marrow donor. In addition to presenting peptides to T cells, HLA-C also functions as a ligand for killing inhibitory receptor...

journal_title：Transplantation

authors： van der Meer A,Allebes WA,Paardekooper J,Ruiter J,Joosten I

更新日期：2001-09-15 00:00:00

abstract：BACKGROUND:We investigated the hypothesis that Foxp3+ cells are an integral component of antiallograft immunity but are dominated by pathogenic effectors. METHODS:Wild-type H-2b C57BL/6 (B6) mice or B6 mice with a targeted disruption of c-Rel gene (c-Rel-/-) were used as recipients of islet grafts from allogeneic DBA/...

journal_title：Transplantation

authors： Yang H,Ding R,Sharma VK,Hilaire FS,Lagman M,Li B,Thomas DA,Luo X,Song P,Stauffer C,August P,Suthanthiran M

更新日期：2007-06-27 00:00:00

abstract：:The particular T cell subsets involved in the rejection of tumor allografts were examined in mice using two different approaches. In the first, EL4 lymphoma cells or B16 melanoma cells were given to ATXBM-CBA/H mice which had been reconstituted with either naive or sensitized T cells selectively depleted with either L...

journal_title：Transplantation

authors： Loveland BE,McKenzie IF

更新日期：1982-02-01 00:00:00

abstract：:Unilateral, intraorganal injection of parental lymph node cells into thyroid lobes of F1 hybrid rats elicited an intense, local graft-versus-host reaction within the injected lobes containing massive numbers of lymphocytes. Surprisingly, significant mononuclear cell infiltration was also seen within the contralateral ...

journal_title：Transplantation

authors： Konetzki WS,Streilein JW

更新日期：1978-05-01 00:00:00

abstract：:Monocytes play a crucial role in the response of lymphocytes to phytomitogens. This role is evident during the very early events after exposure to the mitogen. Thus, significant lymphocyte transformation does occur when monocytes are removed from the culture within a few hours after exposure to mitogen, and the presen...

journal_title：Transplantation

authors： Mookerjee BK,Ballard J

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND:All-cause mortality is high after kidney transplantation (KT), but no prognostic index has focused on predicting mortality in KT using baseline and emergent comorbidity after KT. METHODS:A total of 4928 KT recipients were used to derive a risk score predicting mortality. Patients were randomly assigned to t...

journal_title：Transplantation

authors： Hernández D,Sánchez-Fructuoso A,González-Posada JM,Arias M,Campistol JM,Rufino M,Morales JM,Moreso F,Pérez G,Torres A,Serón D,Spanish Late Allograft Dysfunction Study Group.

更新日期：2009-09-27 00:00:00

abstract：:We studied the role of interleukin (IL)-8 during engraftment after hematopoietic stem cell transplantation. In 40 consecutive patients undergoing either allogeneic marrow (n=32) or autologous peripheral blood stem cell transplantation (n=8), IL-8 plasma levels were serially determined. Median IL-8 concentrations peake...

journal_title：Transplantation

authors： Schwabe M,Hartert AM,Bertz H,Finke J

更新日期：2004-10-15 00:00:00