Graft-versus-host reactions within the thyroid gland may evoke pari passu autoimmune thyroiditis.

abstract：BACKGROUND:Kidney paired donation (KPD) has emerged as a viable option for renal transplant candidates with incompatible living donors. The aim of this study was to assess the "performance" of a three-site KPD program that allowed screening of multiple donors per recipient. METHODS:We reviewed retrospectively the acti...

journal_title：Transplantation

authors： Li H,Stegall MD,Dean PG,Casey ET,Reddy KS,Khamash HA,Heilman RL,Mai ML,Taner CB,Kosberg CL,Bakken LL,Wozniak EJ,Giles KL,Veal LA,Gandhi MJ,Cosio FG,Prieto M

更新日期：2014-08-15 00:00:00

abstract：:Comparative experiments were performed on 41 allogenic rat kidney transplants to determine the mitotic behaviour and proliferative metabolism (application of 3H-thymidine) in the first 6 days after recirculation. Three days after transplantation, DNA synthesis in the tubular epithelial cells of the cortex and the medu...

journal_title：Transplantation

authors： Lauschke H

更新日期：1978-07-01 00:00:00

abstract：BACKGROUND:Renal warm ischemic injury and immunosuppression with cyclosporin A (CsA) may contribute to chronic allograft nephropathy after cadaveric transplantation. This study establishes whether CsA can sensitize the kidney to injury and fibrosis induced by renal warm ischemia (RWI). METHODS:The left kidney of Sprag...

journal_title：Transplantation

authors： Ahmed A,Huang L,Raftery AT,Ahmed AK,Fahmy H,El Nahas AM,Haylor JL

更新日期：2004-03-15 00:00:00

abstract：:Seasonal variation in blood pressure (BP) has been described in the general and dialysis populations, with higher recordings noted in the winter than in the summer. This difference has been attributed to changes in weight, ambient temperature, and length of daylight. In this study, we sought to determine whether such ...

journal_title：Transplantation

authors： Prasad GV,Nash MM,Zaltzman JS

更新日期：2001-12-15 00:00:00

abstract：BACKGROUND:Recent data show the efficacy of embryonic stem cells (ESC) to engraft in allogeneic recipients without host pretreatment. This property is due to their low expression of major histocompatibility complex (MHC) class I antigens and lack of MHC class II expression. Here, we tested the hypothesis that the const...

journal_title：Transplantation

authors： Fabricius D,Bonde S,Zavazava N

更新日期：2005-05-15 00:00:00

abstract：BACKGROUND:Activation of the renin angiotensin system may contribute to the development of delayed graft function after renal transplantation. We, therefore, examined the impact of pretransplant treatment with blockers of the renin angiotensin system on early graft function after renal transplantation. METHOD:The case...

journal_title：Transplantation

authors： Stevens KK,Patel RK,Clancy M,Jardine AG

更新日期：2010-03-27 00:00:00

abstract：BACKGROUND:The management of small bowel transplantation is unique because signs of rejection can be obtained visually by endoscopy. The aim of this study was to evaluate the accuracy of endoscopic appearance in assessing histologic evidence of acute cellular rejection (ACR). METHODS:Endoscopies were performed in 66 a...

journal_title：Transplantation

authors： O'Keefe SJ,El Hajj II,Wu T,Martin D,Mohammed K,Abu-Elmagd K

更新日期：2012-10-15 00:00:00

abstract：BACKGROUND:Belatacept is associated with better renal function and an improved cardiovascular/metabolic risk profile versus cyclosporine in kidney transplant recipients. The current analysis examined pooled safety data for belatacept versus cyclosporine used in combination with basiliximab, mycophenolate mofetil, and s...

journal_title：Transplantation

authors： Grinyó J,Charpentier B,Pestana JM,Vanrenterghem Y,Vincenti F,Reyes-Acevedo R,Apanovitch AM,Gujrathi S,Agarwal M,Thomas D,Larsen CP

更新日期：2010-12-27 00:00:00

abstract：BACKGROUND:Innate immunity plays a role in controlling adaptive immune responses. METHODS:We investigated the clinical relevance of single nucleotide polymorphisms in 22 genes encoding innate, secreted, and signaling pattern recognition receptors in a total of 520 donor-recipient pairs of postmortem, human leukocyte a...

journal_title：Transplantation

authors： Eikmans M,de Canck I,van der Pol P,Baan CC,Haasnoot GW,Mallat MJ,Vergunst M,de Meester E,Roodnat JI,Anholts JD,van Thielen M,Doxiadis II,de Fijter JW,van der Linden PJ,van Beelen E,van Kooten C,Kal-van Gestel JA,Peeters

更新日期：2012-09-15 00:00:00

abstract：:In a prospective randomized double-blind placebo-controlled trial, the effect of rh-SOD, given in a dose of 200 mg intravenously during surgery to cyclosporine-treated recipients of cadaveric renal allografts, on both acute and chronic rejection events as well as patient and graft survival was investigated by analyzin...

journal_title：Transplantation

authors： Land W,Schneeberger H,Schleibner S,Illner WD,Abendroth D,Rutili G,Arfors KE,Messmer K

更新日期：1994-01-01 00:00:00

abstract：:For many individuals suffering from end-stage liver disease (ESLD), the only treatment option is liver transplantation. However, liver transplant rejection is observed in 24-80% of transplant patients and lifelong drug regimens that follow the transplant procedure lead to serious side effects. Furthermore, the pool of...

journal_title：Transplantation

authors： Wang X,MacParland SA,Perciani CT

更新日期：2021-01-06 00:00:00

abstract：:Nonadherence to immunosuppressants in renal transplant recipients is a major factor affecting graft survival, but it is difficult to detect accurately in clinical practice. Adherence was measured in 153 adult renal transplant recipients using self-report questionnaires and interview, clinician rating, and cyclosporine...

journal_title：Transplantation

authors： Butler JA,Peveler RC,Roderick P,Horne R,Mason JC

更新日期：2004-03-15 00:00:00

abstract：:We developed a new and simplified donor-specific blood transfusion (DSBT) protocol for prospective kidney transplant recipients from one-haplotype-mismatched related donors. Prospective kidney donors gave 450 ml of blood in a quad-pack unit, and the blood was stored in a blood bank. Twenty-five patients were transfuse...

journal_title：Transplantation

authors： Cheigh JS,Suthanthiran M,Kaplan M,Evelyn M,Riggio RR,Fotino M,Schechter N,Wolf CF,Stubenbord WT,Stenzel KH

更新日期：1984-11-01 00:00:00

abstract：:A comparative study of 24 hr preservation at 4 degrees C of excised rat livers with Euro-Collins and hydroxyethyl starch-free University of Wisconsin (UWm) solutions has been conducted based on the assessment of (1) the cellular energy status determined by 31P NMR spectroscopy and (2) cellular injury estimated from th...

journal_title：Transplantation

authors： Gulian JM,Dalmasso C,Desmoulin F,Scheiner C,Cozzone PJ

更新日期：1992-10-01 00:00:00

abstract：OBJECTIVES:To determine whether humoral autoimmune responses associated with dilated cardiomyopathy (DCM) influence the postoperative clinical course following cardiac transplantation. METHODS:ELISA levels of preformed cardiac myosin (CM) autoantibodies (Abs) in patients with a pretransplant diagnosis of dilated cardi...

journal_title：Transplantation

authors： Warraich RS,Pomerance A,Stanley A,Banner NR,Dunn MJ,Yacoub MH

更新日期：2000-04-27 00:00:00

abstract：:Infection remains one of the major complications of nonspecific immunosuppression in renal transplant patients and accounts for significant morbidity and mortality. The incidence of infectious complications has been shown to be related to the degree of immunosuppression and correlated with the total steroid dosage, us...

journal_title：Transplantation

authors： Salama AD,Rogers T,Lord GM,Lechler RI,Mason PD

更新日期：1997-01-15 00:00:00

abstract：BACKGROUND:In this study, we investigated the effects of selective endothelin (ET) receptor antagonism during different periods of cold ischemia on glomerular and tubular function and long-term survival in renal transplantation. METHODS:Left renal transplantation was performed in Lewis rats after 2 hr of cold ischemia...

journal_title：Transplantation

authors： Hammad FT,Davis G,Zhang XY,Wheatley AM

更新日期：2001-03-15 00:00:00

abstract：:Apoptotic cells are endowed with immunomodulatory properties. The authors propose infusing apoptotic cells as a cell-based therapy product to facilitate allogeneic hematopoietic engraftment after a nonmyeloablative conditioning regimen. Such an approach may be used to obtain macrochimerism in combined hematopoietic ce...

journal_title：Transplantation

authors： Kleinclauss F,Perruche S,Cahn JY,Tiberghien P,Saas P

更新日期：2003-05-15 00:00:00

abstract：BACKGROUND:Obliterative bronchiolitis (OB), chronic allograft rejection of the lung, is a major cause of morbidity and mortality after lung transplantation. Previous studies using the heterotopic mouse trachea model of chronic airway rejection have shown a T cell infiltrate composed of CD4+ and CD8+ T cells. The goal o...

journal_title：Transplantation

authors： Neuringer IP,Walsh SP,Mannon RB,Gabriel S,Aris RM

更新日期：2000-02-15 00:00:00

abstract：BACKGROUND:Calcineurin inhibitor (CI)-based immunosuppression has prolonged the survival of heart transplant recipients. However, CI-induced renal injury remains as a major problem in these patients. Sirolimus is an immunosuppressant with no significant impact on renal function. A limited number of recent papers have s...

journal_title：Transplantation

authors： Bestetti R,Theodoropoulos TA,Burdmann EA,Filho MA,Cordeiro JA,Villafanha D

更新日期：2006-03-15 00:00:00

abstract：BACKGROUND:Brain death (BD) affects the viability of lungs for transplantation. A correlation exists between high lung inflammation after BD and the decrease in female sex hormones, especially estradiol. Therefore, we investigated the effects of 17β-estradiol (E2) treatment on the lungs of female brain dead rats. METH...

journal_title：Transplantation

authors： Ricardo-da-Silva FY,Armstrong R Jr,Vidal-Dos-Santos M,Correia CJ,Coutinho E Silva RDS,da Anunciação LF,Moreira LFP,Leuvenink HGD,Breithaupt-Faloppa AC

更新日期：2020-10-07 00:00:00

abstract：:The effects of FK506 on exocrine function of the pancreas in Sprague-Dawley rats were examined and compared with those of cyclosporine. FK506 did not affect the levels of amylase and lipase in the pancreas of rats given the drug orally in a daily dose of 1 or 5 mg/kg for 2 weeks. Furthermore, the pancreas of the rats ...

journal_title：Transplantation

authors： Hirano Y,Hisatomi A,Ohara K,Noguchi H

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:Thromboembolism has been reported as a frequent complication after cardiac transplantation. Many risk factors for thrombosis may explain this, such as metabolic alterations and the use of cyclosporine. In the general population, two single nucleotide polymorphisms (SNPs), factor V Leiden and prothrombin G202...

journal_title：Transplantation

authors： Miriuka SG,Langman LJ,Evrovski J,Miner SE,Kozuszko S,D'Mello N,Delgado DH,Wong BY,Ross HJ,Cole DE

更新日期：2005-09-15 00:00:00

abstract：:Blood transfusions are common in patients with end-stage liver disease (ESLD), and their effects on sensitization, rejection, and liver graft survival are not well known. These effects were examined in 121 recipients of primary liver grafts, surviving > or = 30 days. Ninety-six (79%) patients received transfusions bef...

journal_title：Transplantation

authors： Koneru B,Harrison D,Rizwan M,Holland BK,Ippolito T,Holman MJ,Leevy CB

更新日期：1997-06-15 00:00:00

abstract：:Hepatic artery thrombosis is a continuing source of morbidity and mortality following orthotopic liver transplantation. The cornerstone of therapy has been urgent retransplantation that is limited by organ availability. For this reason we developed a policy of urgent revascularization for allograft rescue. Hepatic art...

journal_title：Transplantation

authors： Langnas AN,Marujo W,Stratta RJ,Wood RP,Li SJ,Shaw BW

更新日期：1991-01-01 00:00:00

abstract：:Of 113 cyclosporine-treated primary renal allograft recipients, 60 were randomized to receive standard therapy without diltiazem (ND) and 53 received standard therapy plus diltiazem (D). There was no difference in CsA blood levels between ND and D at all intervals between 3 and 24 months follow-up, yet the D group req...

journal_title：Transplantation

authors： Chrysostomou A,Walker RG,Russ GR,d'Apice AJ,Kincaid-Smith P,Mathew TH

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:We assess whether remote ischemic preconditioning (rIPC) of the recipient can modify ischemia-reperfusion (IR) injury in the donor heart following orthotopic heart transplantation from brain dead donors and to examine potential mechanisms of protection. METHODS:Sixteen pigs weighing from 26 to 34.2 (mean 29...

journal_title：Transplantation

authors： Konstantinov IE,Li J,Cheung MM,Shimizu M,Stokoe J,Kharbanda RK,Redington AN

更新日期：2005-06-27 00:00:00

abstract：BACKGROUND:Kidneys from older donors are likely to have a lower nephron mass. Nevertheless they constitute a valuable source of kidney allografts. Long cold ischemic time (CIT), with or without delayed graft function (DGF), has been associated with reduced graft survival. The aim of this study was to review the experie...

journal_title：Transplantation

authors： Asderakis A,Dyer P,Augustine T,Worthington J,Campbell B,Johnson RW

更新日期：2001-08-27 00:00:00

abstract：:The length of time after syngeneic bone marrow reconstitution when tolerance to alloantigens can be induced in adult mice during T cell differentiation from bone marrow cells was studied by exposing those T cells to (recipient x donor)F1 spleen cells. Supralethally irradiated C3H/He Slc(C3H; H-2k) mice were reconstitu...

journal_title：Transplantation

authors： Tomita Y,Himeno K,Mayumi H,Tokuda N,Nomoto K

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND:Urothelial carcinoma (UC) is a common complication after renal replacement therapy (RRT) among Chinese end-stage renal disease (ESRD) patients. It is unclear whether there are any differences in the clinicopathologic characteristics of UC between renal transplantation (RT) and dialysis patients; such differe...

journal_title：Transplantation

authors： Zhang B,Shen C,Han WK,Yu W

更新日期：2014-09-15 00:00:00