Diltiazem in renal allograft recipients receiving cyclosporine.

abstract：OBJECTIVE:The aim of this prospective, multicenter, noncomparative, open-label trial was to evaluate the prophylactic use of caspofungin in adult liver transplant recipients at high risk of developing invasive fungal infections (IFI). METHODS:Patients received caspofungin for at least 21 days. A successful treatment o...

journal_title：Transplantation

authors： Fortún J,Martín-Dávila P,Montejo M,Muñoz P,Cisneros JM,Ramos A,Aragón C,Blanes M,San Juan R,Gavaldá J,Llinares P,GESITRA Study Group.

更新日期：2009-02-15 00:00:00

abstract：BACKGROUND:Ischemia-reperfusion (I/R) injury after lung transplantation causes alveolar damage, lung edema, and acute rejection. Poly(adenosine diphosphate-ribose) polymerase (PARP) is a single-stranded DNA repair enzyme that induces apoptosis and necrosis after DNA damage caused by reactive oxygen species. We evaluate...

journal_title：Transplantation

authors： Hatachi G,Tsuchiya T,Miyazaki T,Matsumoto K,Yamasaki N,Okita N,Nanashima A,Higami Y,Nagayasu T

更新日期：2014-09-27 00:00:00

abstract：:In a prospective randomized double-blind placebo-controlled trial, the effect of rh-SOD, given in a dose of 200 mg intravenously during surgery to cyclosporine-treated recipients of cadaveric renal allografts, on both acute and chronic rejection events as well as patient and graft survival was investigated by analyzin...

journal_title：Transplantation

authors： Land W,Schneeberger H,Schleibner S,Illner WD,Abendroth D,Rutili G,Arfors KE,Messmer K

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:In organ transplantation, several immunosuppressants are currently used to control graft rejection. Clinically, no single immunosuppressive agent can completely prevent posttransplantation immunoreaction; thus, combination therapy is usually performed. Novel agents with more powerful immunosuppressive activi...

journal_title：Transplantation

authors： Yamamoto S,Okuda T,Yamasaki K,Tanaka H,Kubo S,Takemura S,Ikeda K,Minamiyama Y,Hirohashi K,Suehiro S

更新日期：2004-12-15 00:00:00

abstract：:Heterologous anti-immunoglobulin is a potent immunosuppressive agent that prolongs H-2- and H-3-incompatible skin graft survival. In conjunction with antithymocyte serum, anti-immunoglobulin promotes greater graft life than either antiserum used alone, without evidence of toxicity to recipient animals. Combination tre...

journal_title：Transplantation

authors： Constantian MB,Couser WG,Mannick JA

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND:Human T-cell lymphotropic virus type I (HTLV-I) causes a subacute myelopathy in less than 5% of chronic carriers. However, the risk of neurologic disease appears to increase in persons infected through blood transfusion. METHODS:We report three recipients of solid organ transplants who developed a subacute ...

journal_title：Transplantation

authors： Toro C,Rodés B,Poveda E,Soriano V

更新日期：2003-01-15 00:00:00

abstract：BACKGROUND:Inasmuch as cryopreservation can facilitate clinical islet transplantation by providing a means of storing supplemental islets in order to augment marginally adequate grafts, protocols are needed to allow for a minimal loss in viable beta cells. By replacing the cryoprotectant dimethyl sulfoxide (DMSO) with ...

journal_title：Transplantation

authors： Korbutt GS,Rayat GR,Ezekowitz J,Rajotte RV

更新日期：1997-10-15 00:00:00

abstract：:Clinical observations suggest that recipients of multiorgan transplants from the same donor can have disparate immunological reactions to each organ. We studied this phenomenon in 36 diabetic (streptozotocin-induced), bilaterally nephrectomized immunosuppressed (cyclosporine, azathioprine, prednisone) pig recipients o...

journal_title：Transplantation

authors： Gruessner RW,Nakhleh R,Tzardis P,Schechner R,Platt JL,Gruessner A,Tomadze G,Najarian JS,Sutherland DE

更新日期：1993-12-01 00:00:00

abstract：:Eradicating transplant tourism depends on complex solutions that include efforts to progress towards self-sufficiency in transplantation. Meanwhile, professionals and authorities are faced with medical, legal, and ethical problems raised by patients who return home after receiving an organ transplant abroad, particula...

journal_title：Transplantation

authors： Domínguez-Gil B,Danovitch G,Martin DE,López-Fraga M,Van Assche K,Morris ML,Lavee J,Erlich G,Fadhil R,Busic M,Rankin G,Al-Rukhaimi M,OʼConnell P,Chin J,Norman T,Massari P,Kamel R,Delmonico FL,Declaration of Istanbul Cu

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Alloreactive immune responses may engage both direct and indirect antigen allorecognition. This study focuses on T-cell receptor (TCR) beta-chain usage by in vitro generated alloreactive CD4+ T cells involved in direct allorecognition pathway. METHODS AND RESULTS:We have established Lewis anti-Brown Norway ...

journal_title：Transplantation

authors： Zhai Y,Kupiec-Weglinski JW

更新日期：2003-02-27 00:00:00

abstract：:Flow cytometry (FC) T and B cell crossmatches were done retrospectively for 38 cadaver renal transplant recipients (29 first and 9 retransplants--minimum follow-up 12 months) using both current pretransplant serum and peak-reactive sera. An increase in median fluorescence intensity (channel shift) and/or an increase i...

journal_title：Transplantation

authors： Lazda VA,Pollak R,Mozes MF,Jonasson O

更新日期：1988-03-01 00:00:00

abstract：:Predictors of survival after lung transplant were analyzed in a large cohort of 990 lung transplanted patients from a single center. The overall survival was 41.6%, (41.5% in males, and 41.8% in females), the average length of the follow up was 45.84+/-51.98 months (range 0-282.47 months). Females tend to live longer ...

journal_title：Transplantation

authors： Creel M,Studer SM,Schwerha J,Harper J,Ortiz L,Ragin C,Taioli E

更新日期：2008-04-27 00:00:00

abstract：BACKGROUND:Postoperative damage of the urethral rhabdosphincter and nerve-vascular networks is a major complication of radical prostatectomy and generally causes incontinence and/or erectile dysfunction. The human skeletal muscle-derived stem cells, which have a synchronized reconstitution capacity of muscle-nerve-bloo...

journal_title：Transplantation

authors： Nakajima N,Tamaki T,Hirata M,Soeda S,Nitta M,Hoshi A,Terachi T

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Calcineurin inhibitor (CI)-based immunosuppression has prolonged the survival of heart transplant recipients. However, CI-induced renal injury remains as a major problem in these patients. Sirolimus is an immunosuppressant with no significant impact on renal function. A limited number of recent papers have s...

journal_title：Transplantation

authors： Bestetti R,Theodoropoulos TA,Burdmann EA,Filho MA,Cordeiro JA,Villafanha D

更新日期：2006-03-15 00:00:00

abstract：:Patient entry is now complete in a prospective trial of anti-Tac, a murine IgG2a monoclonal antibody directed against the p55 chain of the human IL-2 receptor, for the prevention of renal allograft rejection. Recipients of primary cadaver allografts were randomized to receive either anti-Tac (20 mg q.d. x 10 days begi...

journal_title：Transplantation

authors： Kirkman RL,Shapiro ME,Carpenter CB,McKay DB,Milford EL,Ramos EL,Tilney NL,Waldmann TA,Zimmerman CE,Strom TB

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Although human herpesvirus (HHV)-6 is now recognized as a frequent pathogen after transplantation, the real impact of this infection in patients undergoing transplantation remains unclear. METHODS:During 27 months, 30 consecutive heart-lung- and lung-transplant recipients were included on the day of transpl...

journal_title：Transplantation

authors： Jacobs F,Knoop C,Brancart F,Gilot P,Mélot C,Byl B,Delforge ML,Estenne M,Liesnard C,Brussels Heart and Lung Transplantation Group.

更新日期：2003-06-27 00:00:00

abstract：:Serologic evidence of resolved hepatitis B virus (HBV) infection (HBV surface antigen negative, anti-HBV core antibody [HBc] positive) in a liver donor can be regarded as an occult infection with episomal HBV in the liver. The purpose of this study was to evaluate the safety of anti-HBc-positive living donors. Between...

journal_title：Transplantation

authors： Hwang S,Moon DB,Lee SG,Park KM,Kim KH,Ahn CS,Lee YJ,Chu CW,Yang HS,Cho SH,Oh KB,Ha TY,Min PC

更新日期：2003-02-15 00:00:00

abstract：:Zero-time kidney biopsies, obtained at time of transplantation, are performed in many transplant centers worldwide. Decisions on kidney discard, kidney allocation, and choice of peritransplant and posttransplant treatment are sometimes based on the histological information obtained from these biopsies. This comprehens...

journal_title：Transplantation

authors： Naesens M

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Successful pancreatic islet transplantation (PIT) has resulted in several transplant centers wanting to start PIT programs. PIT remains experimental and must be performed safely for its continued use. We describe the radiographic techniques used at our center and their results. METHODS:Between January 17, 2...

journal_title：Transplantation

authors： Goss JA,Soltes G,Goodpastor SE,Barth M,Lam R,Brunicardi FC,Froud T,Alejandro R,Ricordi C

更新日期：2003-07-15 00:00:00

abstract：BACKGROUND:In cases where hyperacute rejection has been prevented, pig to primate organ transplantation results in a delayed rejection mediated by graft-infiltrating leukocytes. The migration of human leukocytes across porcine endothelium is poorly characterized, but may offer targets for species-specific antirejection...

journal_title：Transplantation

authors： Hauzenberger E,Hauzenberger D,Hultenby K,Holgersson J

更新日期：2000-05-15 00:00:00

abstract：:Incompatibility for DBA/2 (D2) minor histocompatibility antigens (MiHA) alone leads to a severe lethal graft-versus-host reaction (GVHR) in irradiated (D2 X B10.D2)F1 mice receiving a bone-marrow-plus-spleen-cell graft from B10.D2 donors. This mortality is abrogated when the donors are preimmunized simultaneously agai...

journal_title：Transplantation

authors： Pritchard LL,Halle-Pannenko O

更新日期：1983-09-01 00:00:00

abstract：BACKGROUND:Survival after lung transplantation is mainly limited by the development of chronic lung allograft dysfunction (CLAD). The aim of this study was to investigate if platelet inhibition by clopidogrel has a functionally relevant influence on the microvascular integrity of orthotopic tracheal allografts as an an...

journal_title：Transplantation

authors： Heim C,Khan MA,von Silva-Tarouca B,Kuckhahn A,Stamminger T,Ramsperger-Gleixner M,Nicolls MR,Weyand M,Ensminger SM

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Blood group-incompatible transplantation is one strategy used when a potential recipient does not have a compatible living donor. Current practice includes desensitization strategies to reduce antibody titers. However, when antibodies are low, in cardiac transplantation in neonates for example, no desensitiz...

journal_title：Transplantation

authors： Barnett AN,Hudson A,Hadjianastassiou VG,Marks SD,Reid CJ,Maggs TP,Vaughan R,Mamode N

更新日期：2012-08-27 00:00:00

abstract：BACKGROUND:To identify factors related with successful pregnancy in renal transplant recipients and the effect of pregnancy on long-term graft outcome. METHODS:The study group consisted of 48 women who conceived after undergoing renal transplantation (total pregnancies 74). The control group consisted of 187 nonpregna...

journal_title：Transplantation

authors： Kim HW,Seok HJ,Kim TH,Han DJ,Yang WS,Park SK

更新日期：2008-05-27 00:00:00

abstract：BACKGROUND:Perioperative renal dysfunction in liver transplant recipients complicates maintenance immunosuppressive therapy, particularly in patients with hepatitis C. Calcineurin inhibitors exacerbate renal dysfunction and mammalian target-of-rapamycin inhibitors are generally avoided because of perceived perioperativ...

journal_title：Transplantation

authors： LaMattina JC,Jason MP,Hanish SI,Ottmann SE,Klassen DK,Potosky D,Hutson WR,Barth RN

更新日期：2014-01-27 00:00:00

abstract：BACKGROUND:Early calcineurin inhibitor (CNI) withdrawal with mycophenolate mofetil (MMF) has not become routine practice, due to concerns about excess acute rejection. Therapeutic drug monitoring may be advantageous when the CNI or MMF is withdrawn. METHODS:This prospective, randomized, concentration-controlled withdr...

journal_title：Transplantation

authors： Mourer JS,Hartigh Jd,van Zwet EW,Mallat MJ,Dubbeld J,de Fijter JW

更新日期：2012-05-15 00:00:00

abstract：BACKGROUND:The innovative pure laparoscopic living donor right hepatectomy (LLDRH) procedure for liver transplantation has never been fully compared to open living donor right hepatectomy (OLDRH). We aimed to compare the donor safety and graft results of pure LLDRH to those of OLDRH. METHODS:From May 2013 to July 2017...

journal_title：Transplantation

authors： Park J,Kwon DCH,Choi GS,Kim SJ,Lee SK,Kim JM,Lee KW,Chung YJ,Kim KS,Lee JS,Rhu J,Kim GS,Gwak MS,Ko JS,Lee JE,Lee S,Joh JW

更新日期：2019-10-01 00:00:00

abstract：:Comparative experiments were performed on 41 allogenic rat kidney transplants to determine the mitotic behaviour and proliferative metabolism (application of 3H-thymidine) in the first 6 days after recirculation. Three days after transplantation, DNA synthesis in the tubular epithelial cells of the cortex and the medu...

journal_title：Transplantation

authors： Lauschke H

更新日期：1978-07-01 00:00:00

abstract：BACKGROUND:Liver transplant recipients for hepatitis C virus (HCV)-related cirrhosis usually remain anti-HCV-seropositive after transplantation. The aim of this study was to characterize, longitudinally, the profile of HCV-specific antibodies and cryoglobulins in liver transplant recipients with recurrent HCV infection...

journal_title：Transplantation

authors： Gane EJ,Maertens G,Ducatteeuw A,Qian KP,Lau JY,Jones H,Davies E,Naoumov NV,Williams R

更新日期：1999-01-15 00:00:00

abstract：:Since chemotaxis is an important mechanism by which leukocytes are recruited to allografts during rejection, the effect of immunosuppressant agents on in vitro chemotactic responses of neutrophils, monocytes, and lymphocytes was studied. Cyclosporine caused profound inhibition of lymphocyte chemotaxis to three differe...

journal_title：Transplantation

authors： Adams DH,Wang LF,Neuberger JM,Elias E

更新日期：1990-11-01 00:00:00