Tacrolimus (FK506) and cyclosporine reduce the uptake and transport of particles into rabbit Peyer's patches.

abstract：:Nuclear imaging is used to evaluate renal allografts demonstrating delayed function after transplantation. Interpretation of the nuclear scan in the context of clinical data, provides helpful information in the management of the transplant recipient. The better quality of images obtained with technetium-99m mercaptoac...

journal_title：Transplantation

authors： Mange KC,Scheff A,Brayman K,Mozley D,Grossman RA,Naji A,Aradhye S

更新日期：1997-11-27 00:00:00

abstract：:The major role of anti-alphaGal antibodies in the hyperacute rejection of pig organs by humans and baboons has been clearly demonstrated. Spacered alpha-galactose disaccharide (Gal(alpha1)-3Gal) hapten was produced by chemical synthesis and covalently attached to a flexible, hydrophilic polymer (PAA), which in turn wa...

journal_title：Transplantation

authors： Taniguchi S,Neethling FA,Korchagina EY,Bovin N,Ye Y,Kobayashi T,Niekrasz M,Li S,Koren E,Oriol R,Cooper DK

更新日期：1996-11-27 00:00:00

abstract：BACKGROUND:Living kidney donors have donation-related out-of-pocket costs (direct costs) and/or ongoing daily expenses while losing income (indirect costs). Yet there is little information about how much of a subjective burden these constitute for the donors. METHODS:From December 2003 through December 2014, we survey...

journal_title：Transplantation

authors： Wiseman JF,Jacobs CL,Larson DB,Berglund DM,Garvey CA,Ibrahim HN,Matas AJ

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:The organ donor shortage has led to a reconsideration of the use of non-heart-beating donors (NHBDs). However, graft injury due to warm ischemia in NHBD livers strongly affects posttransplant outcome. The present study was aimed at investigating the role of the cellular cyclic (c)AMP second messenger signal ...

journal_title：Transplantation

authors： Minor T,Akbar S

更新日期：1998-10-27 00:00:00

abstract：BACKGROUND:Community respiratory viruses such as respiratory syncytial virus (RSV), adenovirus, influenza A, influenza B, and the parainfluenza group are frequent causes of respiratory disease in bone marrow transplant (BMT) patients. MATERIAL AND METHODS:During the period from March 1993 to August 1999, 810 samples o...

journal_title：Transplantation

authors： Raboni SM,Nogueira MB,Tsuchiya LR,Takahashi GA,Pereira LA,Pasquini R,Siqueira MM

更新日期：2003-07-15 00:00:00

abstract：:We have tested the predictive model for risk of sensitization by donor-specific transfusions developed at the University of California, San Francisco for its applicability to the DST experience at UW/Madison. Patient sample sizes between the two groups were similar (n = 249 for UW/Madison, n = 261 for UCSF) and the tw...

journal_title：Transplantation

authors： Burlingham WJ,Stratta R,Mason B,Lorentzen D,Feyzi J,Sollinger HW,Belzer FO

更新日期：1989-01-01 00:00:00

abstract：:Renal allograft recipients treated with cyclosporine (CsA) have increased renal vascular resistance that falls when CsA is stopped. With the aim of identifying whether CsA-treated patients with excellent renal function also have an alteration in renal vascular tone and to investigate which vessels are affected, we hav...

journal_title：Transplantation

authors： Cairns HS,Raval U,Neild GH

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND:Malnutrition is common in patients with end-stage liver disease considered for transplantation, but it is unclear whether this affects the outcome after transplantation. AIM.: To determine whether the severity of malnutrition in liver transplant candidates affects outcome after transplantation. METHODS:We d...

journal_title：Transplantation

authors： Shahid M,Johnson J,Nightingale P,Neuberger J

更新日期：2005-02-15 00:00:00

abstract：BACKGROUND:Guillain-Barre Syndrome (GBS) is believed to be caused by autoimmune mechanisms that are predominantly T-cell mediated. We report GBS in organ transplant patients and bone marrow transplant patients, both of whom have iatrogenically suppressed T-cell function. METHODS:We reviewed the Duke University Medical...

journal_title：Transplantation

authors： Bulsara KR,Baron PW,Tuttle-Newhall JE,Clavien PA,Morgenlander J

更新日期：2001-04-27 00:00:00

abstract：BACKGROUND:Subclinical T cell-mediated rejection (subTCMR) is commonly found after liver transplantation and has a good short-term prognosis, even when it is left untreated. Donor-specific antibodies (DSA) are putatively associated with a worse prognosis for recipient and graft after liver transplantation. METHODS:To ...

journal_title：Transplantation

authors： Höfer A,Jonigk D,Hartleben B,Verboom M,Hallensleben M,Hübscher SG,Manns MP,Jaeckel E,Taubert R

更新日期：2020-03-01 00:00:00

abstract：:Flow cytometry (FC) is increasingly being used as a crossmatch procedure in addition to the standard complement-dependent cytotoxicity (CDC) test. In fact, FC offers a number of advantages over CDC and has the potential to become the primary crossmatch technique for cadaveric donor renal transplantation. We evaluated ...

journal_title：Transplantation

authors： Scornik JC,Brunson ME,Schaub B,Howard RJ,Pfaff WW

更新日期：1994-02-27 00:00:00

abstract：BACKGROUND:Both number and origin (donor vs. host) of dendritic cells (DC) are associated with acute graft-versus-host disease (aGvHD), relapse and graft failure after human allogeneic hematopoietic cell transplantation (aHCT). METHODS:We prospectively and simultaneously investigated skin and blood DC subtypes, their ...

journal_title：Transplantation

authors： Auffermann-Gretzinger S,Eger L,Bornhäuser M,Schäkel K,Oelschlaegel U,Schaich M,Illmer T,Thiede C,Ehninger G

更新日期：2006-03-27 00:00:00

abstract：:The value of percutaneous core needle biopsy in the immunohistological evaluation of renal allograft dysfunction was studied in 72 consecutive biopsies performed in 42 patients. The phenotypes of infiltrating cells mediating graft destruction were identified with monoclonal antibodies and immunoperoxidase staining tec...

journal_title：Transplantation

authors： Waltzer WC,Miller F,Arnold A,Anaise D,Rapaport FT

更新日期：1987-01-01 00:00:00

abstract：:Created by the US National Organ Transplant Act in 1984, the Scientific Registry of Transplant Recipients (SRTR) is obligated to publicly report data on transplant program and organ procurement organization performance in the United States. These reports include risk-adjusted assessments of graft and patient survival,...

journal_title：Transplantation

authors： Snyder JJ,Salkowski N,Kim SJ,Zaun D,Xiong H,Israni AK,Kasiske BL

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:This study evaluated the prognostic impact of pretransplant donor-specific anti-human leukocyte antigen antibodies (DSA) detected by single-antigen beads and compared the three generations of crossmatch (XM) tests in kidney transplantation. METHODS:Thirty-seven T-cell complement-dependent cytotoxicity cross...

journal_title：Transplantation

authors： Riethmüller S,Ferrari-Lacraz S,Müller MK,Raptis DA,Hadaya K,Rüsi B,Laube G,Schneiter G,Fehr T,Villard J

更新日期：2010-07-27 00:00:00

abstract：BACKGROUND:The role of asymptomatic bacteriuria in kidney transplant recipients is unknown. There is no clear evidence of its effect on transplanted kidney. METHODS:We studied urine cytokines profile among kidney transplant recipients with bacteriuria found in screening examination. Urine cultures were collected in 26...

journal_title：Transplantation

authors： Ciszek M,Paczek L,Bartłomiejczyk I,Mucha K

更新日期：2006-06-27 00:00:00

abstract：BACKGROUND:It has been postulated that chimerism after transplantation might promote graft acceptance. In the present study, we prospectively assessed blood chimerism in 10 lung transplant recipients during the first posttransplant year and investigated whether chimerism was associated with an immunologically stable si...

journal_title：Transplantation

authors： Knoop C,Andrien M,Defleur V,Antoine M,de Francquen P,Goldman M,Estenne M

更新日期：1997-07-15 00:00:00

abstract：:After the progressive improvement in the results of organ transplantation we now face the challenge of shortage in organ supply. The decreasing number of organ retrievals performed in 1990 at our hospital has raised questions concerning loss of potential organ donors and opposition to donation by the next of kin. We i...

journal_title：Transplantation

authors： Faltin DL,Jeannet M,Suter PM

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:In France, the need for continuous monitoring of transplant center performance has recently become apparent. Cumulative sum (CUSUM) monitoring of transplantation is already been used to monitor transplant outcomes in the United Kingdom and in the United States. Because CUSUM monitoring can be applied by diff...

journal_title：Transplantation

authors： Alexandrine B,Savoye E,Pessione F,Cantrelle C,Jasseron C,Santin G,Bastien O,Legeai C

更新日期：2019-09-01 00:00:00

abstract：:It was the objective of these experiments to study the time-related changes in the responsiveness of the cellular elements of the immune system following contact with single non-H-2 or multiple H-2 histocompatibility antigens. The reactivity of spleen cells from mice that received injections of spleen cells bearing H-...

journal_title：Transplantation

authors： Graff RJ,Kurtz ME,Russell H,Martin-Morgan D

更新日期：1988-02-01 00:00:00

abstract：:Predictors of survival after lung transplant were analyzed in a large cohort of 990 lung transplanted patients from a single center. The overall survival was 41.6%, (41.5% in males, and 41.8% in females), the average length of the follow up was 45.84+/-51.98 months (range 0-282.47 months). Females tend to live longer ...

journal_title：Transplantation

authors： Creel M,Studer SM,Schwerha J,Harper J,Ortiz L,Ragin C,Taioli E

更新日期：2008-04-27 00:00:00

abstract：:The frequencies of circulating donor-reactive cytotoxic lymphocyte precursors (CLP) and Il-2-producing helper lymphocyte precursors (HLP) were determined by limiting dilution analysis in 19 kidney allograft recipients before and at various intervals (up to 2 years) after transplantation. A significant, selective, and ...

journal_title：Transplantation

authors： Zanker B,Jooss-Rüdiger J,Franz HE,Wagner H,Kabelitz D

更新日期：1993-09-01 00:00:00

abstract：:The effect of cyclosporine on lymphocyte intracellular free calcium [( Ca2+]i) is controversial, and potential age-related differences in lymphocyte CsA sensitivity have not been studied. We measured the mitogen-induced change in [Ca2+]i in peripheral blood lymphocytes (PBLs) following intravenous CsA infusion (5 mg/k...

journal_title：Transplantation

authors： Tsao PW,Diaz RJ,Radde IC,Wong PY,Martell MF,Augustine JM,Wilson GJ,Coles JG

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:The long-term metabolic function of microencapsulated xenogeneic adult porcine islets (API) was assessed in a murine model of type 1 diabetes mellitus. METHODS:API were encapsulated in barium-gelled alginate and transplanted intraperitoneally in diabetic nonobese diabetic (NOD) mice given no immunosuppressi...

journal_title：Transplantation

authors： Cui H,Tucker-Burden C,Cauffiel SM,Barry AK,Iwakoshi NN,Weber CJ,Safley SA

更新日期：2009-07-27 00:00:00

abstract：:The histopathological features of chronic rejection and its initiation were assessed using rat heterotopic heart transplantation and retransplantation models. Fully allogeneic or minor, non-MHC antigen-mismatch heart grafts transplanted into recipient rats treated with a short course of FK506 showed long-term survival...

journal_title：Transplantation

authors： Izutani H,Miyagawa S,Shirakura R,Matsumiya G,Nakata S,Shimazaki Y,Matsuda H

更新日期：1995-11-27 00:00:00

abstract：BACKGROUND:Chronic graft-versus-host disease (cGVHD) represents a double-edged sword. In its nonsevere form, cGVHD associates with better control of the malignant disease, thus highlighting graft-versus-leukemia effects. However, severe cGVHD leads to debilitating morbidity and increased nonrelapse mortality. The predi...

journal_title：Transplantation

authors： Giesen N,Schwarzbich MA,Dischinger K,Becker N,Hummel M,Benner A,Radujkovic A,Müller-Tidow C,Dreger P,Luft T

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:In a recent trial, targeted mild hypothermia in brain-dead organ donors significantly reduced the incidence of delayed graft function after kidney transplantation. This trial was stopped early for efficacy. Here, we report long-term graft survival for all organs along with donor critical care end points. ME...

journal_title：Transplantation

authors： Malinoski D,Patel MS,Axelrod DA,Broglio K,Lewis RJ,Groat T,Niemann CU

更新日期：2019-11-01 00:00:00

abstract：:In organ transplantation, blood borne cells and macromolecules (e.g., antibodies) of the host immune system are brought into direct contact with the endothelial cell lining of graft vessels. In this location, graft endothelial cells play several roles in allograft rejection, including the initiation of rejection respo...

journal_title：Transplantation

authors： Al-Lamki RS,Bradley JR,Pober JS

更新日期：2008-11-27 00:00:00

abstract：BACKGROUND:Cytomegalovirus (CMV) replication has been associated with more risk for solid organ graft rejection. We wondered whether this association still holds when patients at risk receive prophylactic treatment for CMV. METHODS:We correlated CMV infection, biopsy-proven graft rejection, and graft loss in 1,414 pat...

journal_title：Transplantation

authors： Stern M,Hirsch H,Cusini A,van Delden C,Manuel O,Meylan P,Boggian K,Mueller NJ,Dickenmann M,Members of Swiss Transplant Cohort Study.

更新日期：2014-11-15 00:00:00

abstract：:The effect of FK506 and cyclosporine on NK and ADCC activity was evaluated. Cytotoxic cells mediating both activities are resistant to FK506. In contrast, preincubation of ADCC and NK effectors with cyclosporine decreases their cytotoxic potential, while adding the drug to the assays is without effect. ...

journal_title：Transplantation

authors： Wasik M,Gorski A,Stepien-Sopniewska B,Lagodzinski Z

更新日期：1991-01-01 00:00:00