Abstract:
:BK polyoma virus causes allograft dysfunction as a result of tubulo-interstitial nephritis in 2% to 5% of renal transplant recipients. The incidence of BK virus infection among renal transplant recipients in India is unknown. We used routine histologic examination, immunohistochemistry, and electron microscopy to retrospectively screen for BK polyoma virus in 414 renal allograft biopsy specimens from 321 transplant recipients presenting with allograft dysfunction. All patients had received a combination of cyclosporine, azathioprine, and prednisolone. A total of 30 biopsy specimens (9.3%) were positive for BK polyoma virus, suggesting a high incidence of this infection in Indian transplant recipients. BK virus infection coexisted with acute rejection in a majority of patients. This is the first report of this infection among Indian renal transplant recipients.
journal_name
Transplantationjournal_title
Transplantationauthors
Sachdeva MS,Nada R,Jha V,Sakhuja V,Joshi Kdoi
10.1097/01.TP.0000113163.02039.30subject
Has Abstractpub_date
2004-02-15 00:00:00pages
429-31issue
3eissn
0041-1337issn
1534-6080pii
00007890-200402150-00021journal_volume
77pub_type
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