Abstract:
:Allotransplantation into immunosuppressed individuals results in long-term survival of grafts. However, the grafts are damaged, probably at many stages before, during and after implantation. The hypothesis to be presented is that release of antigens and autoantigens from the chronically damaged graft results in breaking tolerance to self-antigens and an autoimmune response. There is experimental evidence that autoimmune responses following allotransplantation are damaging and cause accelerated graft rejection.
journal_name
Transplantationjournal_title
Transplantationauthors
Rose MLdoi
10.1097/01.tp.0000153294.38939.5fsubject
Has Abstractpub_date
2005-02-15 00:00:00pages
S22-4issue
3 Suppleissn
0041-1337issn
1534-6080pii
00007890-200502151-00008journal_volume
79pub_type
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