Non-major histocompatibility system immunogenetic influences in rat renal allograft survival.

Abstract:

:H-1-incompatible rat renal allograft survival rates are strongly influenced by the non-major histocompatibility system (MHS) genes. The same H-1 (MHS) incompatibility tested on four different non-MHS backgrounds gave widely differing results ranging from 11 to 60% fractional survival between the best and the poorest (P less than 0.01) at 105 days. These results can best be explained if non-H-1 and intra-MHS amplifiers and/or suppressors are invoked.

journal_name

Transplantation

journal_title

Transplantation

authors

Paris AM,Bishop C,Festenstein H,Gunther E

doi

10.1097/00007890-197805000-00006

subject

Has Abstract

pub_date

1978-05-01 00:00:00

pages

252-4

issue

5

eissn

0041-1337

issn

1534-6080

journal_volume

25

pub_type

杂志文章
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