MicroRNA-155 Deficiency in Kupffer Cells Ameliorates Liver Ischemia-Reperfusion Injury in Mice.

abstract：:Rapid and precise cyclosporine measurements are necessary to maximize immunosuppression and minimize toxicity. The new cyclosporine and metabolites TDx fluorescent polarization immunoassay was studied to determine its precision, sensitivity, and stability. Further, it was compared with the existing radioimmunoassay an...

journal_title：Transplantation

authors： Schroeder TJ,Brunson ME,Pesce AJ,Hindenlang LL,Mauser PA,Ruckrigl DI,Weibel ML,Wadih G,First MR

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND:Preexisting IgG antibodies to donor human leukocyte antigens (HLA) are a risk factor for rapid allograft rejection. However, non-HLA antibodies, of the IgM class, also called autoreactive antibodies, are not believed to affect graft survival. The aim of this study was to determine the incidence and clinical ...

journal_title：Transplantation

authors： Smith JD,Hamour IM,Burke MM,Mahesh B,Stanford RE,Haj-Yahia S,Robinson DR,Kaul P,Yacoub MH,Banner NR,Rose ML

更新日期：2009-03-27 00:00:00

abstract：BACKGROUND:Cardiac allograft vasculopathy (CAV) still limits survival after heart transplantation. Currently available noninvasive tests are of inferior value to detect CAV, and thus invasive coronary angiography (ICA) is frequently performed. Cardiac dual-source computed tomography calcium scoring (DSCTCS) offers the ...

journal_title：Transplantation

authors： von Ziegler F,Kaczmarek I,Knez A,Greif M,Rümmler J,Meiser B,Reichart B,Becker C,Steinbeck G,Becker A

更新日期：2011-08-27 00:00:00

abstract：:Mandatory continuous monitoring of early transplant outcome with centralized oversight was introduced in 2004 for all 23 UK adult kidney transplant units. Risk-adjusted cumulative sum charts are used to assess 30-day graft and patient survival against past performance for each center, and change in transplant center p...

journal_title：Transplantation

authors： Collett D,Sibanda N,Pioli S,Bradley JA,Rudge C

更新日期：2009-10-27 00:00:00

abstract：BACKGROUND:Both number and origin (donor vs. host) of dendritic cells (DC) are associated with acute graft-versus-host disease (aGvHD), relapse and graft failure after human allogeneic hematopoietic cell transplantation (aHCT). METHODS:We prospectively and simultaneously investigated skin and blood DC subtypes, their ...

journal_title：Transplantation

authors： Auffermann-Gretzinger S,Eger L,Bornhäuser M,Schäkel K,Oelschlaegel U,Schaich M,Illmer T,Thiede C,Ehninger G

更新日期：2006-03-27 00:00:00

abstract：BACKGROUND:Specific tolerance after combined kidney and bone marrow transplantation for multiple myeloma with end-stage renal disease through mixed lymphohematopoietic chimerism has been achieved, as evidenced by prolonged normal renal function without ongoing immunosuppression. METHODS:To achieve potent antimyeloma r...

journal_title：Transplantation

authors： Spitzer TR,Sykes M,Tolkoff-Rubin N,Kawai T,McAfee SL,Dey BR,Ballen K,Delmonico F,Saidman S,Sachs DH,Cosimi AB

更新日期：2011-03-27 00:00:00

abstract：OBJECTIVES:To retrospectively compare the accuracy of pretransplant panel of reactivity antibodies (PRA) and serum level of soluble CD30 (sCD30) in predicting early (< 6 months) acute rejection (AR) in living-donor and deceased-donor kidney-transplant (KT) patients. METHODS:Pretransplant sera of 24 KT recipients were ...

journal_title：Transplantation

authors： Cinti P,Pretagostini R,Arpino A,Tamburro ML,Mengasini S,Lattanzi R,De Simone P,Berloco P,Molajoni ER

更新日期：2005-03-15 00:00:00

abstract：BACKGROUND:Cold preservation is the most practical method to maintain the viability of isolated lungs. However, rapid cooling may affect pulmonary endothelial function. We examined the effects of microtubule stabilization with paclitaxel on pulmonary endothelial barrier integrity under cold temperature. METHODS:Human ...

journal_title：Transplantation

authors： Suzuki S,Bing H,Sugawara T,Matsuda Y,Tabata T,Hoshikawa Y,Saijo Y,Kondo T

更新日期：2004-08-27 00:00:00

abstract：BACKGROUND:Pneumocystis jirovecii pneumonia (PJP) is an important infection-related complication, whose mode of transmission remains uncertain. METHODS:We investigated a nosocomial cluster of 14 PJP cases (11 confirmed and 3 probable) in kidney transplant recipients using epidemiological and genotyping methods. RESUL...

journal_title：Transplantation

authors： Phipps LM,Chen SC,Kable K,Halliday CL,Firacative C,Meyer W,Wong G,Nankivell BJ

更新日期：2011-12-27 00:00:00

abstract：BACKGROUND:A widely held view is that any increase in the potency of an immunosuppressive agent will lead to an increase in infection and malignancy, such as life-threatening Epstein-Barr virus (EBV) induced posttransplant lymphoproliferative disorders (PTLD). We tested this paradigm by studying the effect of adding mo...

journal_title：Transplantation

authors： Birkeland SA,Andersen HK,Hamilton-Dutoit SJ

更新日期：1999-05-15 00:00:00

abstract：:A monoclonal anti-Lyt-1.1 serum has been characterized in terms of its effect on various cell populations involved in cell-mediated immune responses. The monoclonal serum was compared to a conventionally prepared anti-Lyt-1.1 serum. Cytotoxic T cell precursors and effectors were found to be Lyt-1.1+. Helper T cells wh...

journal_title：Transplantation

authors： Shaw J,Pilarski LM,Al Adra AR,Leigh JB,Wilkins J,Hogarth PM,McKenzie IF,Paetkau V

更新日期：1981-01-01 00:00:00

abstract：:We describe a patient transfused with 200 ml of donor fresh whole blood three times at 2-week intervals. Three weeks after the last transfusion, transplantation and splenectomy were done at the same time. Splenic cells from this DST pretreated patient were fused with murine myeloma cells (X63-Ag8, 653). With DST pretr...

journal_title：Transplantation

authors： Kawamura T,Sakagami K,Haisa M,Morisaki F,Takasu S,Inagaki M,Oiwa T,Orita K

更新日期：1989-09-01 00:00:00

abstract：:The frequencies of circulating donor-reactive cytotoxic lymphocyte precursors (CLP) and Il-2-producing helper lymphocyte precursors (HLP) were determined by limiting dilution analysis in 19 kidney allograft recipients before and at various intervals (up to 2 years) after transplantation. A significant, selective, and ...

journal_title：Transplantation

authors： Zanker B,Jooss-Rüdiger J,Franz HE,Wagner H,Kabelitz D

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:Recipient antidonor cytotoxic T-cell activity has been associated with graft loss and acute rejection in renal allograft recipients. The role of immunologic mechanisms in the development of chronic graft rejection is controversial. We analyzed all living related renal transplants performed at Children's Hosp...

journal_title：Transplantation

authors： Alexander SI,Younes SB,Yunis JJ,Zurakowski D,Mirza N,Dubey D,Drew MP,Harmon WE,Yunis EJ

更新日期：1997-06-27 00:00:00

abstract：BACKGROUND:The authors investigated the cognitive status during the late postoperative phase in children who had undergone liver transplantation (LTx). METHODS:The authors examined 44 children who had undergone liver transplantation at their center. The children were 8.9+/-2.3 (mean+/-SD) years of age and had received...

journal_title：Transplantation

authors： Kaller T,Schulz KH,Sander K,Boeck A,Rogiers X,Burdelski M

更新日期：2005-05-15 00:00:00

abstract：:Allogeneic lymphocyte cytotoxicity (ALC) describes the elimination of allogeneic lymphocytes in vivo by an NK-related activity. There is evidence that ALC is demonstrable between donor and recipient when these are incompatible at MHC gene loci alone. Since ALC is a property of T cell-deficient nude rats, the role of t...

journal_title：Transplantation

authors： Ager A,Fajumi J,Sparshott SM,Ford WL,Butcher GW

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND:Both chemokines and adhesion molecules mediate allograft rejection by recruiting leukocytes into the allograft. We investigated the association of six single nucleotide polymorphisms (SNPs) located in interleukin (IL)-8, CXCR1, CXCR2, and selectin with kidney allograft outcomes. METHODS:The promoter regions...

journal_title：Transplantation

authors： Ro H,Hwang YH,Kim H,Jeong JC,Lee H,Doh YS,Park HC,Oh KH,Park MH,Ha J,Yang J,Ahn C

更新日期：2011-01-15 00:00:00

abstract：:We present the youngest successful patient with combined heart-lung-liver transplantation. The patient was a 2.5-year-old child with Alagille syndrome suffering from tetralogy of Fallot with pulmonary atresia and multiple aortopulmonary collaterals and familial cholestasis. ...

journal_title：Transplantation

authors： Gandhi SK,Reyes J,Webber SA,Siewers RD,Pigula FA

更新日期：2002-06-27 00:00:00

abstract：:Immunomodulatory properties are attributed to apoptotic cells. These properties have been used to modulate allogeneic immune responses in experimental transplantation settings. In independent studies, apoptotic cell infusion has been shown to favor hematopoietic cell engraftment, to increase heart graft survival, and ...

journal_title：Transplantation

authors： Saas P,Bonnefoy F,Kury-Paulin S,Kleinclauss F,Perruche S

更新日期：2007-07-15 00:00:00

abstract：:We developed a new and simplified donor-specific blood transfusion (DSBT) protocol for prospective kidney transplant recipients from one-haplotype-mismatched related donors. Prospective kidney donors gave 450 ml of blood in a quad-pack unit, and the blood was stored in a blood bank. Twenty-five patients were transfuse...

journal_title：Transplantation

authors： Cheigh JS,Suthanthiran M,Kaplan M,Evelyn M,Riggio RR,Fotino M,Schechter N,Wolf CF,Stubenbord WT,Stenzel KH

更新日期：1984-11-01 00:00:00

abstract：BACKGROUND:Natural antibodies (NAbs) against a terminal alpha1-3 galactosyl (alphaGal) epitope have been identified as the major human anti-pig NAbs. METHODS AND RESULTS:We used two synthetic alphaGal trisaccharides--type 6 (alphaGal6) and type 2(alphaGal2)--linked to an inert matrix to remove NAbs from human plasma i...

journal_title：Transplantation

authors： Xu Y,Lorf T,Sablinski T,Gianello P,Bailin M,Monroy R,Kozlowski T,Awwad M,Cooper DK,Sachs DH

更新日期：1998-01-27 00:00:00

abstract：:Three strains of miniature swine, each homozygous for a different allele of the major histocompatibility locus (MHC), have been developed by a selective breeding scheme based on tissue typing of the offspring of each generation. Prior to breeding, the original parents were reciprocally immunized by skin grafts and lym...

journal_title：Transplantation

authors： Sachs DH,Leight G,Cone J,Schwarz S,Stuart L,Rosenberg S

更新日期：1976-12-01 00:00:00

abstract：BACKGROUND:Socioeconomic variables including low income and noncompliance impact negatively upon long-term renal allograft survival, especially in African Americans. We sought to determine whether other socioeconomic variables contributed to noncompliance and allograft survival. METHODS:A detailed history of socioecon...

journal_title：Transplantation

authors： Butkus DE,Dottes AL,Meydrech EF,Barber WH

更新日期：2001-07-27 00:00:00

abstract：:Clinical as well as experimental studies have shown a great interindividual variability in the immunosuppressive efficacy of CsA. Evaluating previous in vitro findings of a correlation between sensitivity of alloresponsiveness to CsA and the HLA-DR phenotype CsA levels were compared in kidney transplant recipients wit...

journal_title：Transplantation

authors： Zlabinger GJ,Kudlacek S,Pohanka E,Franz M,Hamilton G,Rosenmayr A,Kovarik J

更新日期：1992-04-01 00:00:00

abstract：OBJECTIVE:The aim of this prospective, multicenter, noncomparative, open-label trial was to evaluate the prophylactic use of caspofungin in adult liver transplant recipients at high risk of developing invasive fungal infections (IFI). METHODS:Patients received caspofungin for at least 21 days. A successful treatment o...

journal_title：Transplantation

authors： Fortún J,Martín-Dávila P,Montejo M,Muñoz P,Cisneros JM,Ramos A,Aragón C,Blanes M,San Juan R,Gavaldá J,Llinares P,GESITRA Study Group.

更新日期：2009-02-15 00:00:00

abstract：:Tolerance induction by CD45RB monoclonal antibody (mAb) in murine allograft models is associated with an alteration in the CD45RBlo/CD45RBhi T-cell ratio in favor of CD45RBlo T cells, which can function as regulatory cells and promote tolerance. It has been proposed that inversion of the CD45RBhi/CD45RBlo normal T-cel...

journal_title：Transplantation

authors： Luke PP,Deng JP,O'Brien CA,Everest M,Hall AV,Chakrabarti S,O'Connell PJ,Zhong R,Jevnikar AM

更新日期：2003-07-27 00:00:00

abstract：:Previous reports have failed to demonstrate integumentary allograft rejection in insects. We realized however, that these studies may not have fully appreciated the structure of the insect exoskeleton. Since the subcuticlar epidermal layer constitutes the only living tissue associated with insect integument, its destr...

journal_title：Transplantation

authors： George JF,Howcroft TK,Karp RD

更新日期：1987-04-01 00:00:00

abstract：BACKGROUND:Long-term use of immunosuppressants is associated with significant morbidity and mortality in transplant recipients. A simple whole blood assay that has U.S. Food and Drug Administration clearance directly assesses the net state of immune function of allograft recipients for better individualization of thera...

journal_title：Transplantation

authors： Kowalski RJ,Post DR,Mannon RB,Sebastian A,Wright HI,Sigle G,Burdick J,Elmagd KA,Zeevi A,Lopez-Cepero M,Daller JA,Gritsch HA,Reed EF,Jonsson J,Hawkins D,Britz JA

更新日期：2006-09-15 00:00:00

abstract：:This study describes VG01, a monoclonal antibody to a novel lymphocyte activation antigen. The cells reacting with VG01 were first characterized by indirect immunofluorescence and fluorescence-activated cell sorter analysis. The antigen defined by VG01 was expressed on circulating T lymphocytes (23.8 +/- 9.0) and on t...

journal_title：Transplantation

authors： Denegri JF,Gilks CB,Altin M,Peterson J,Lafleur L

更新日期：1988-05-01 00:00:00

abstract：BACKGROUND:Perioperative renal dysfunction in liver transplant recipients complicates maintenance immunosuppressive therapy, particularly in patients with hepatitis C. Calcineurin inhibitors exacerbate renal dysfunction and mammalian target-of-rapamycin inhibitors are generally avoided because of perceived perioperativ...

journal_title：Transplantation

authors： LaMattina JC,Jason MP,Hanish SI,Ottmann SE,Klassen DK,Potosky D,Hutson WR,Barth RN

更新日期：2014-01-27 00:00:00