Role of donor leukocyte chimerism in establishing the etiology of neutropenia after liver transplantation.

abstract：INTRODUCTION:Cytomegalovirus infection after heart transplantation is considered as risk factor for the development of transplant arteriosclerosis. Therefore, the aim of this study was to investigate the effect of murine cytomegalovirus (MCMV) as a single risk factor on transplant arteriosclerosis in an experimental ao...

journal_title：Transplantation

authors： Heim C,Abele-Ohl S,Eckl S,Ramsperger-Gleixner M,Mahmoudian S,Weyand M,Stamminger T,Ensminger SM

更新日期：2010-08-27 00:00:00

abstract：:Shortage of organ donors limits the number of possible liver transplantations. Alternative therapies for treatment of liver failure are currently being developed: (i) extracorporeal artificial liver devices; (ii) bioartificial liver devices using hepatocytes; and (iii) hepatocyte transplantation. The objective of thes...

journal_title：Transplantation

authors： Sgroi A,Serre-Beinier V,Morel P,Bühler L

更新日期：2009-02-27 00:00:00

abstract：BACKGROUND:Successful kidney transplantation normalizes elevated proatrial natriuretic peptide (proANP) plasma concentrations of renal failure patients in the early posttransplant period. We evaluated plasma and urinary proANP fragments in the late posttransplant period. METHODS:Immunoreactive proANP(1-30) and proANP(...

journal_title：Transplantation

authors： Franz M,Woloszczuk W,Hörl WH

更新日期：2001-07-15 00:00:00

abstract：:Healthy rat islets were encapsulated in alginate-polylysine-alginate capsules measuring 0.25-0.35 mm in diameter using a modified encapsulation technique. The encapsulated islets were transplanted intraperitoneally in nonimmunosuppressed streptozotocin-induced diabetic BALB/c mice. The diabetic condition of the experi...

journal_title：Transplantation

authors： Lum ZP,Krestow M,Tai IT,Vacek I,Sun AM

更新日期：1992-06-01 00:00:00

abstract：:The prevalence of angiographically proven coronary artery disease (CAD) in adults with end-stage liver disease who undergo evaluation for liver transplantation is unknown; also it is unclear if cholestatic liver disease represents an independent risk factor. Patients with end-stage liver disease over age 50 having liv...

journal_title：Transplantation

authors： Carey WD,Dumot JA,Pimentel RR,Barnes DS,Hobbs RE,Henderson JM,Vogt DP,Mayes JT,Westveer MK,Easley KA

更新日期：1995-03-27 00:00:00

abstract：BACKGROUND:CD154 mediates key facets of humoral and cellular immunity to alloantigens, and is tolerogenic to influenza antigens in primates. Barriers to CD154-based tolerance induction for primate cardiac allografts have not previously been defined. METHODS:Heterotopic cardiac allograft outcomes in cynomolgus monkeys ...

journal_title：Transplantation

authors： Azimzadeh AM,Pfeiffer S,Wu G,Schröder C,Zorn GL 3rd,Kelishadi SS,Ozkaynak E,Kehry M,Atkinson JB,Miller GG,Pierson RN 3rd

更新日期：2006-01-27 00:00:00

abstract：BACKGROUND:Preconditioning protects against both liver and lung damage after hepatic ischemia-reperfusion (I/R). Xanthine and xanthine oxidase (XOD) may contribute to the development of hepatic I/R. OBJECTIVE:To evaluate whether preconditioning could modulate the injurious effects of xanthine/XOD on the liver and lung...

journal_title：Transplantation

authors： Peralta C,Bulbena O,Xaus C,Prats N,Cutrin JC,Poli G,Gelpi E,Roselló-Catafau J

更新日期：2002-04-27 00:00:00

abstract：BACKGROUND:Alterations in microcirculation are considered central to the pathogenesis of hyperacute xenogeneic rejection (HXR) of vascularized xenografts, but currently there exist no data describing these microhemodynamic alterations. METHODS:Rat livers were perfused in situ with either isogeneic rat blood or xenogen...

journal_title：Transplantation

authors： Seehofer D,Baatz H,Thiery J,Müller-Hocker J,Müller-Derlich J,Hammer C

更新日期：1997-02-15 00:00:00

abstract：BACKGROUND:Individuals undergoing therapeutic immunosuppression are at risk of severe varicella-zoster virus (VZV) infection, particularly those without evidence of previous infection. METHODS:Eleven children, median age 10 months (range 5.5 months to 7 years and 9 months) received one dose of varicella vaccine (Varil...

journal_title：Transplantation

authors： Donati M,Zuckerman M,Dhawan A,Hadzic N,Heaton N,North-Lewis P,Mieli-Vergani G

更新日期：2000-11-15 00:00:00

abstract：BACKGROUND:It has been suggested that T cells primed by processed donor major histocompatibility complex antigen (the "indirect" pathway of allorecognition) may be responsible for mediating chronic allograft rejection. The purpose of this study was to develop a clinically useful assay to study the occurrence of indirec...

journal_title：Transplantation

authors： Vella JP,Spadafora-Ferreira M,Murphy B,Alexander SI,Harmon W,Carpenter CB,Sayegh MH

更新日期：1997-09-27 00:00:00

abstract：BACKGROUND:Kidney grafts with multiple renal arteries have been considered a relative contraindication because of the increased risk of complications. In the present study, we retrospectively reviewed multiple renal artery reconstruction in kidney transplantation to elucidate the usefulness of these grafts. METHODS:Fr...

journal_title：Transplantation

authors： Makiyama K,Tanabe K,Ishida H,Tokumoto T,Shimmura H,Omoto K,Toma H

更新日期：2003-03-27 00:00:00

abstract：BACKGROUND:The role of combined liver-kidney transplantation (CLKT) for cirrhotic patients with renal failure (RF) is controversial. Since the model for end-stage liver disease era, there has been a rise in the number of CLKT. Using the Organ Procurement Transplant Network/United Network for Organ Sharing database, thi...

journal_title：Transplantation

authors： Fong TL,Khemichian S,Shah T,Hutchinson IV,Cho YW

更新日期：2012-08-27 00:00:00

abstract：BACKGROUND:Because CD4CD25Foxp3 regulatory T cells (Tregs) are essential for the maintenance of self-tolerance, significant interest surrounds the developmental cues for thymic-derived natural Tregs (nTregs) and periphery-generated adaptive Tregs (aTregs). In the transplant setting, the allograft may play a role in the...

journal_title：Transplantation

authors： Kim JI,O'connor MR,Duff PE,Zhao G,Lee KM,Eliades P,Deng S,Yeh H,Caton AJ,Markmann JF

更新日期：2011-04-15 00:00:00

abstract：:Immunosuppressive therapy increases the risk of recurrence of initial cancers in organ transplant patients, and compelling therapeutic protocols are needed to suppress the malignancy and protect the allograft. We examined the potential use of 15-deoxyspergualin (DSG) in relation to organ transplantation and cancer. Th...

journal_title：Transplantation

authors： Ohsawa I,Uemoto S,Kobayashi E,Murakami T

更新日期：2007-08-15 00:00:00

abstract：:It has been demonstrated both in vivo and in vitro that cytomegalovirus regulates not only MHC class I but also class II antigen expression on vascular endothelial cells. The CMV-linked MHC induction is believed to be involved in acute rejection mechanisms and chronic vasculopathy after transplantation. In this study,...

journal_title：Transplantation

authors： Ustinov JA,Lahtinen TT,Bruggeman CA,Häyry PJ,Lautenschlager IT

更新日期：1994-11-15 00:00:00

abstract：:Conjugation of dextran-coated superparamagnetic iron oxide (SPIO) particles with transactivator protein (Tat)-peptide and fluorescein isothiocyanate (FITC) allows cells to readily uptake SPIO particles. This makes possible high-resolution, real-time imaging of these cells by magnetic resonance imaging (MRI). First, we...

journal_title：Transplantation

authors： Kaufman CL,Williams M,Ryle LM,Smith TL,Tanner M,Ho C

更新日期：2003-10-15 00:00:00

abstract：BACKGROUND:We reviewed the incidence of and risk factors for venous thromboembolic complications in our population of kidney (KTx) and simultaneous kidney-pancreas transplant (SPK) recipients. METHODS:Information was collected retrospectively from a database on 1833 KTx and 276 SPK recipients who underwent transplant ...

journal_title：Transplantation

authors： Humar A,Johnson EM,Gillingham KJ,Sutherland DE,Payne WD,Dunn DL,Wrenshall LE,Najarian JS,Gruessner RW,Matas AJ

更新日期：1998-01-27 00:00:00

abstract：BACKGROUND:Transjugular intrahepatic portosystemic shunt (TIPS) is used in the management of refractory ascites (RA) and variceal bleeds. Little data exist on TIPS safety, efficacy, and survival after liver transplantation (LT). METHODS:We conducted a retrospective analysis of patients who underwent TIPS placement aft...

journal_title：Transplantation

authors： Feyssa E,Ortiz J,Grewal K,Azhar A,Parsikia A,Tufail K,Hashemi N,Brady P,Araya V

更新日期：2011-04-15 00:00:00

abstract：:The nature of cell-mediated immunity in the American cockroach (Periplaneta americana) was studied by observing the events involved in graft reactivity. Adult roaches received integumentary xenografts from Blaberus giganteus, as well as control autografts. Grafts were scored histologically by counting the number of nu...

journal_title：Transplantation

authors： George JF,Karp RD,Rheins LA

更新日期：1984-05-01 00:00:00

abstract：:Pancreatic transplantation is intended to normalize carbohydrate metabolism in insulin-dependent diabetics by restoring endogenous insulin release, and it is usually performed together with kidney transplantation in patients with end-stage renal failure. A major problem in these patients is the daily control of the gr...

journal_title：Transplantation

authors： Secchi A,Pontiroli AE,Traeger J,Dubernard JM,Touraine JL,Ruitton A,Blanc N,Pozza G

更新日期：1983-04-01 00:00:00

abstract：:This study evaluated the utility of duplex Doppler sonograms (DS) and the resistive index (RI) in the identification and differential diagnosis of various causes of renal allograft dysfunction. The efficacy of DS and RI was studied either during acute episodes of allograft dysfunction or during periodic posttransplant...

journal_title：Transplantation

authors： Meyer M,Paushter D,Steinmuller DR

更新日期：1990-12-01 00:00:00

abstract：:We report on the to date largest recovery of 11 organs from a single deceased donor with the transplantation of face, bilateral upper extremities, heart, 1 lung, liver (split for 2 recipients), kidneys, pancreas, and intestine. Although logistically challenging, this case demonstrates the feasibility and safety of the...

journal_title：Transplantation

authors： Tullius SG,Pomahac B,Kim HB,Carty MJ,Talbot SG,Nelson HM,Delmonico FL

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Exercise training is effective in improving the cardiovascular risk profiles of nontransplanted patients, but the health benefits and potential harms of routine exercise training after solid organ transplantation are unclear. This study aims to assess the health benefits and harms of supervised exercise trai...

journal_title：Transplantation

authors： Didsbury M,McGee RG,Tong A,Craig JC,Chapman JR,Chadban S,Wong G

更新日期：2013-03-15 00:00:00

abstract：:Although ELISA on purified HLA molecules for detecting anti-HLA antibody (P-S ELISA) does detect some antibodies previously missed by the conventional complement dependent cytotoxicity method (C Cytotox), HLA ELISA should not fail to detect antibodies already detected by the conventional reference method to be able to...

journal_title：Transplantation

authors： Pierquin A,Masson D,Toupance O,Tabary T,Bougy F,Bensa JC,Chanard J,Cohen JH

更新日期：1996-11-27 00:00:00

abstract：INTRODUCTION:Patients after solid organ transplantation are at an increased risk for microbial infections. Due to therapeutic immunosuppression, the response to active immunizations may be reduced. The serological efficacy of pneumococcal and influenza vaccination was studied in heart transplant recipients. PATIENTS A...

journal_title：Transplantation

authors： Dengler TJ,Strnad N,Bühring I,Zimmermann R,Girgsdies O,Kubler WE,Zielen S

更新日期：1998-11-27 00:00:00

abstract：BACKGROUND:Recent data indicate that factors other than erythropoietin (EPO), such as insulin-like growth factor 1 (IGF-1), can promote erythropoiesis in vitro and correct the anemia of chronic renal failure in vivo. IGF-1 is produced by the liver under growth hormone control, as well as by other sources, including the...

journal_title：Transplantation

authors： Morrone LF,Di Paolo S,Logoluso F,Schena A,Stallone G,Giorgino F,Schena FP

更新日期：1997-09-27 00:00:00

abstract：BACKGROUND:Survival following liver transplantation for hepatitis C virus (HCV) is significantly poorer than for liver transplants performed for other causes of chronic liver disease. The factors responsible for the inferior outcome in HCV+ recipients, and whether they differ from factors associated with survival in HC...

journal_title：Transplantation

authors： Velidedeoglu E,Mange KC,Frank A,Abt P,Desai NM,Markmann JW,Reddy R,Markmann JF

更新日期：2004-06-27 00:00:00

abstract：:To evaluate the efficacy of University of Wisconsin (UW) solution for lung preservation, we performed canine lung allotransplantation with lungs preserved in UW solution. Donor lungs from eight dogs were flushed with UW solution and lungs from four dogs with Euro-Collins solution, and these were preserved for 24 hr in...

journal_title：Transplantation

authors： Kawahara K,Itoyanagi N,Takahashi T,Akamine S,Kobayashi M,Tomota M

更新日期：1993-01-01 00:00:00

abstract：:Cross sensitization between the products of the H-2K and H-2D loci has been demonstrated by an experimental design in which recipients were sensitized with tissue bearing determinants controlled by one locus (e.g., H-2K), and then challenged with skin grafts expressing determinants controlled by the other locus (e.g.,...

journal_title：Transplantation

authors： Murphy DB,Shreffler DC

更新日期：1975-07-01 00:00:00

abstract：:Over the decade between 2003 and 2012, the UK has seen major changes in how organ donation and transplantation is delivered. The number of deceased organ donors has increased from 709 (12.0 per million population [pmp]) to 1,164 (18.3 pmp); this increase has been predominantly a result of an increase in donors after c...

journal_title：Transplantation

authors： Johnson RJ,Bradbury LL,Martin K,Neuberger J,UK Transplant Registry.

更新日期：2014-01-15 00:00:00