Exercise training in solid organ transplant recipients: a systematic review and meta-analysis.

abstract：:Endothelial damage has been implicated in the pathogenesis of chronic rejection. Conversely, expression of protective genes [including A20, A1, bcl-xl, and hemoxygenase-1 (HO-1)] in the endothelium has been associated with long-term graft survival. Overexpression of protective genes in cultured endothelial cells confe...

journal_title：Transplantation

authors： Evans PC,Taylor ER,Kilshaw PJ

更新日期：2001-02-15 00:00:00

abstract：BACKGROUND:This study is designed to examine a possible association of cardiopulmonary bypass (CPB) support and outcome of lung transplantation in a well-balanced group of emphysema patients. METHODS:We performed a retrospective analysis of 62 consecutive primary bilateral lung transplantations for emphysema. Risk fac...

journal_title：Transplantation

authors： de Boer WJ,Hepkema BG,Loef BG,van der Bij W,Verschuuren EA,de Vries HJ,Lems SP,Ebels T

更新日期：2002-05-27 00:00:00

abstract：:Two technical modifications have been suggested for whole-pancreas transplantation with bladder drainage. The duodenal button technique (DB [Madison]) and the duodenal segment technique (DS [Iowa]) are the most commonly performed procedures (1,2). From December 1985 until May 1988 we performed 32 combined pancreas-kid...

journal_title：Transplantation

authors： D'Alessandro AM,Sollinger HW,Stratta RJ,Kalayoglu M,Pirsch JD,Belzer FO

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:The terminal Gal alpha1,3Galactose (alphaGal) determinant is present on all porcine glycoproteins and glycolipids, but is not expressed by human cells. Consequently human sera contain anti-alphaGal natural antibodies. The human blood group B antigen [Gal alpha1,3(Fuc1,2)Galactose] is differentiated from the ...

journal_title：Transplantation

authors： McMorrow IM,Comrack CA,Nazarey PP,Sachs DH,DerSimonian H

更新日期：1997-08-15 00:00:00

abstract：:In liver allograft rejection, interlobular bile ducts are thought to be the main target of rejection. In contrast, in other organ allografts the capillary bed of the graft appears to be the primary target. To determine whether portal tract microvasculature is destroyed in liver allografts during rejection, we have ide...

journal_title：Transplantation

authors： Matsumoto Y,McCaughan GW,Painter DM,Bishop GA

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:Kidney donors and transplant recipients may be at risk of complications from glomerular hyperfiltration of the single kidney. It has been assumed that tests of the existence of renal functional reserve [delta glomerular filtration rate (deltaGFR), delta effective renal plasma flow (deltaERPF)] can be used to...

journal_title：Transplantation

authors： Englund M,Berg U

更新日期：2000-11-15 00:00:00

abstract：:The potent immunosuppressive action of rabbit antithymocyte globulin (RATG) in allotransplant recipients has been recognized for many years. Some of the antibody specificities and immunoregulatory effects of RATG have been described, but a comprehensive definition of RATG components has not been reported previously. I...

journal_title：Transplantation

authors： Rebellato LM,Gross U,Verbanac KM,Thomas JM

更新日期：1994-03-15 00:00:00

abstract：BACKGROUND:Cyclosporine A (CsA)-associated oxidative stress has been proposed as an important mechanism of renal injury. This study was designed to examine whether N-acetylcysteine (NAC), a well-known antioxidant, affects Klotho, antiaging gene, expression and its signaling pathway in an experimental model of chronic C...

journal_title：Transplantation

authors： Piao SG,Kang SH,Lim SW,Chung BH,Doh KC,Heo SB,Jin L,Li C,Yang CW

更新日期：2013-07-27 00:00:00

abstract：BACKGROUND:Infections are a major cause of morbidity and mortality in kidney allograft recipients. In this post hoc analysis of a randomized clinical trial which tested the effect of denosumab on bone mineral density, we assessed the impact of this drug on the incidence and severity of infections in the first year afte...

journal_title：Transplantation

authors： Bonani M,Frey D,de Rougemont O,Mueller NJ,Mueller TF,Graf N,Wüthrich RP

更新日期：2017-09-01 00:00:00

abstract：:Longitudinal studies over an eight-month period have been performed to follow the T killer response restoration after allogeneic bone marrow transplantation (BMT). The capacity of the patient's peripheral blood mononuclear cells (PBM) to develop cytotoxic effector cells directed either against allogeneic cells or agai...

journal_title：Transplantation

authors： Tilkin AF,Bagot M,Dreyfus F,Kayibanda M,Cordonnier C,Vernant JP,Levy JP

更新日期：1987-08-01 00:00:00

abstract：:The early detection of allograft rejection remains elusive after solitary pancreas transplantation (PTX). We have previously described a modified technique of cystoscopic transduodenal PTX biopsy using the Biopty gun under ultrasound guidance. During the last 2 years, we performed 24 solitary PTXs with prospective pro...

journal_title：Transplantation

authors： Stratta RJ,Taylor RJ,Grune MT,Sindhi R,Sudan D,Castaldo P,Cushing KA,Radio SJ,Wisecarver JL,Matamoros A

更新日期：1995-12-27 00:00:00

abstract：:Ling Zhi-8 (LZ-8) is a protein derived from the fungus Ganoderma lucidum and has immunomodulatory capacities. It was shown to be mitogenic toward mouse splenocytes in vitro and immunosuppressive in vivo by reducing antigen-induced antibody formation and by preventing completely the incidence of autoimmune diabetes in ...

journal_title：Transplantation

authors： van der Hem LG,van der Vliet JA,Bocken CF,Kino K,Hoitsma AJ,Tax WJ

更新日期：1995-09-15 00:00:00

abstract：BACKGROUND:The use of liver allografts from an older donor (OD) (age>50 years) is a widespread strategy to manage the disparity between supply and demand of organs for liver transplantation. This study determines the effect of OD allografts on fibrosis progression and graft survival after liver transplantation in patie...

journal_title：Transplantation

authors： Machicao VI,Bonatti H,Krishna M,Aqel BA,Lukens FJ,Nguyen JH,Rosser BG,Satyanarayana R,Grewal HP,Hewitt WR,Harnois DM,Crook JE,Steers JL,Dickson RC

更新日期：2004-01-15 00:00:00

abstract：:Orthotopic liver transplantation is frequently associated with a complex coagulation disorder, influencing the outcome of the procedure. In this respect, disseminated intravascular coagulation (DIC) had been suggested to be of causative importance for bleeding complications after reperfusion of the liver graft. In 10 ...

journal_title：Transplantation

authors： Riess H,Jochum M,Machleidt W,Himmelreich G,Blumhardt G,Roissaint R,Neuhaus P

更新日期：1991-09-01 00:00:00

abstract：:Two distinct pulmonary vascular disorders, hepatopulmonary syndrome (HPS) and portopulmonary hypertension (POPH) may occur as a consequence of hepatic parenchymal or vascular abnormalities. HPS and POPH have major clinical implications for liver transplantation. A European Respiratory Society Task Force on Pulmonary-H...

journal_title：Transplantation

authors： Krowka MJ,Fallon MB,Kawut SM,Fuhrmann V,Heimbach JK,Ramsay MA,Sitbon O,Sokol RJ

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Sensitization to human leukocyte antigens (HLA) is a significant barrier to transplantation. Currently, no proven therapy exists to improve access to transplantation for highly sensitized patients. Here, we report a novel approach using intravenous immune globulin to modulate anti-HLA antibody and improve th...

journal_title：Transplantation

authors： Jordan SC,Vo A,Bunnapradist S,Toyoda M,Peng A,Puliyanda D,Kamil E,Tyan D

更新日期：2003-08-27 00:00:00

abstract：:A 55-year-old woman underwent orthotopic liver transplantation for autoimmune chronic active hepatitis. Extensive portal and superior mesenteric venous thrombosis precluded standard portal venous reconstruction and necessitated use of a venous conduit from the recipient splenic vein of the donor liver. Flow through th...

journal_title：Transplantation

authors： Neelamekam TK,Geoghegan JG,Curry M,Hegarty JE,Traynor O,McEntee GP

更新日期：1997-04-15 00:00:00

abstract：:India with a population of 1.2 billion has a renal transplantation rate of 3.25 per million population. The major cause of chronic kidney disease is hypertension and diabetes. The crude and age-adjusted incidence rates of end-stage renal disease are estimated to be 151 and 232 per million population, respectively, in ...

journal_title：Transplantation

authors： Abraham G,Reddy YN,Amalorpavanathan J,Daniel D,Roy-Chaudhury P,Shroff S,Reddy Y

更新日期：2012-04-27 00:00:00

abstract：BACKGROUND:Thromboembolism has been reported as a frequent complication after cardiac transplantation. Many risk factors for thrombosis may explain this, such as metabolic alterations and the use of cyclosporine. In the general population, two single nucleotide polymorphisms (SNPs), factor V Leiden and prothrombin G202...

journal_title：Transplantation

authors： Miriuka SG,Langman LJ,Evrovski J,Miner SE,Kozuszko S,D'Mello N,Delgado DH,Wong BY,Ross HJ,Cole DE

更新日期：2005-09-15 00:00:00

abstract：BACKGROUND:The detection of acute rejection in heart transplantation remains an important feature of transplant management, especially in the early phase. Frequent surveillance with endomyocardial biopsy is necessary, even though it is an invasive procedure and carries a certain risk. Hence, noninvasive biomarkers able...

journal_title：Transplantation

authors： Crescioli C,Buonamano A,Scolletta S,Sottili M,Francalanci M,Giomarelli P,Biagioli B,Lisi G,Pradella F,Serio M,Romagnani P,Maccherini M

更新日期：2009-01-27 00:00:00

abstract：BACKGROUND:Although chronic kidney disease (CKD) is still a common complication, the prognosis of kidney function after liver transplantation (LT) is not well known. Moreover, kidney function after LT in children with renal involvement is unknown. METHODS:We retrospectively analyzed patients aged <20 years who underwe...

journal_title：Transplantation

authors： Sato M,Kaneko T,Ogura M,Kamei K,Ito S,Fukuda A,Sakamoto S,Kasahara M,Ishikura K

更新日期：2019-08-01 00:00:00

abstract：:Thirteen renal allograft recipients (6 patients on cyclosporine/7 patients on azathioprine) participated in a short-term oral protein-loading study to determine the effect of cyclosporine on an allograft's functional reserve. The baseline glomerular filtration rate of the two groups were similar (52 +/- 18 ml/min/1.73...

journal_title：Transplantation

authors： Nunley JR,King A,Comstock T,Posner M,Marshall C,Sica DA

更新日期：1991-01-01 00:00:00

abstract：:The stability of HLA alloantibodies was studied in 128 antibody-positive, potential kidney transplant recipients over an average period of 3 years. Antibody detection was performed using an anti-human globulin-complement-dependent cytotoxicity technique. In this study, the specificity of antibodies was categorized as ...

journal_title：Transplantation

authors： Rodey GE,Revels K,Fuller TC

更新日期：1997-03-27 00:00:00

abstract：BACKGROUND:A regimen consisting of antilymphocyte serum (ALS), sirolimus, and donor bone-marrow-cell (BMC) infusion induces indefinite skin allograft survival across fully mismatched mouse strain combinations. We investigated the role of chimerism in this transplantation tolerance model. MATERIALS:B10.A (H-2a) mice we...

journal_title：Transplantation

authors： Kanamoto A,Monaco AP,Maki T

更新日期：2004-09-27 00:00:00

abstract：BACKGROUND:Previous reports have established the feasibility of using livers from controlled, non-heart-beating donors (CNHBD) with good immediate graft function. This has been largely borne out of necessity because of the donor shortage. METHODS:Retrospective database review for the last 7 years (1995-2002), encompas...

journal_title：Transplantation

authors： Manzarbeitia CY,Ortiz JA,Jeon H,Rothstein KD,Martinez O,Araya VR,Munoz SJ,Reich DJ

更新日期：2004-07-27 00:00:00

abstract：INTRODUCTION:Immune privilege provides a natural paradigm for potentially down-regulating allogeneic and xenogeneic inflammatory immune responses. Fas ligand has been suggested as a general underlying mechanism of immune privilege; the human Fas ligand has been shown to ligate murine Fas in vitro. METHODS:In this stud...

journal_title：Transplantation

authors： Kimmel SG,Ohbatake M,Kushida M,Merguerian P,Clarke ID,Kim PC

更新日期：2000-03-27 00:00:00

abstract：BACKGROUND:Renal transplant patients have an increased incidence of skin cancers, predominantly on sun-exposed surfaces. Clinical observation identified some patients with an increased number of viral warts, keratoses, and skin malignancies on the side of the arteriovenous fistula. METHODS:In a population of 980 patie...

journal_title：Transplantation

authors： Bordea C,Cortina-Borja M,Wojnarowska F,Morris PJ

更新日期：2001-01-15 00:00:00

abstract：:HLAs are fundamental to the adaptive immune response and play critical roles in the cellular and humoral response in solid organ transplantation. The genes encoding HLA proteins are the most polymorphic within the human genome, with thousands of different allelic variants known within the population. Application of th...

journal_title：Transplantation

authors： Kransdorf EP,Pando MJ,Gragert L,Kaplan B

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:At present, autologous intestinal segments are often used for bladder reconstruction. However, the gastrointestinal mucosa often causes various complications. METHODS:Oral mucosal tissues were obtained from the buccal cavity of beagle dogs. Primary oral mucosal epithelial cells were cultured on temperature-...

journal_title：Transplantation

authors： Watanabe E,Yamato M,Shiroyanagi Y,Tanabe K,Okano T

更新日期：2011-04-15 00:00:00

abstract：BACKGROUND:When a deceased-donor kidney is offered to a waitlisted candidate, the decision to accept or decline the organ relies primarily upon a practitioner's experience and intuition. Such decisions must achieve a delicate balance between estimating the immediate benefit of transplantation and the potential for futu...

journal_title：Transplantation

authors： Bertsimas D,Kung J,Trichakis N,Wojciechowski D,Vagefi PA

更新日期：2017-12-01 00:00:00