Abstract:
:Islet transplantation is currently being explored as a treatment for patients with type 1 diabetes. At present, the number of patients becoming insulin-independent is rapidly increasing world-wide applying the transplantation protocol originally described by the group in Edmonton. A hallmark in this procedure is repeated infusions of islets obtained from 2 to 4 donors until normoglycemia is achieved. In order to establish islet transplantation as a widely accepted treatment modality, and make tolerance induction regimes applicable, it is essential that the donor:recipient ratio is brought down to 1:1. A conceivable strategy to achieve this goal in clinical islet transplantation is discussed.
journal_name
Transplantationjournal_title
Transplantationauthors
Korsgren O,Nilsson B,Berne C,Felldin M,Foss A,Kallen R,Lundgren T,Salmela K,Tibell A,Tufveson Gdoi
10.1097/01.tp.0000157273.60147.7csubject
Has Abstractpub_date
2005-05-27 00:00:00pages
1289-93issue
10eissn
0041-1337issn
1534-6080pii
00007890-200505270-00003journal_volume
79pub_type
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