Comparing the tube and gel techniques for ABO antibody titration, as performed in three European centers.

abstract：:Eight patients with chronic myeloid leukemia relapse after allogeneic BMT were treated with IFN-alpha and buffy coat transfusions (BC) of the bone marrow donor. The antileukemic effect of this treatment was directly demonstrated in 4 patients by the disappearance of Philadelphia chromosome-positive metaphases or the l...

journal_title：Transplantation

authors： Hertenstein B,Wiesneth M,Novotny J,Bunjes D,Stefanic M,Heinze B,Hübner G,Heimpel H,Arnold R

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:IgG antibodies to HLA class I antigens can cause hyperacute rejection of renal allografts. Screening of sera from such transplant candidates is laborious, time-consuming, and expensive when performed by sensitive antihuman globulin-augmented lymphocytotoxicity (AHG-CDC). METHODS:Because 60-70% of our transp...

journal_title：Transplantation

authors： Moore SB,Ploeger NA,DeGoey SR

更新日期：1997-12-15 00:00:00

abstract：BACKGROUND:Donor-specific immune tolerance has been reported in isolated cases of kidney transplantation associated with bone marrow transplantation. The following is a description of a living donor liver transplantation for a hilar cholangiocarcinoma in a previous recipient of an allogeneic bone marrow transplant. ME...

journal_title：Transplantation

authors： Kadry Z,Mullhaupt B,Renner EL,Bauerfeind P,Schanz U,Pestalozzi BC,Studer G,Zinkernagel R,Clavien PA

更新日期：2003-09-27 00:00:00

abstract：:Created by the US National Organ Transplant Act in 1984, the Scientific Registry of Transplant Recipients (SRTR) is obligated to publicly report data on transplant program and organ procurement organization performance in the United States. These reports include risk-adjusted assessments of graft and patient survival,...

journal_title：Transplantation

authors： Snyder JJ,Salkowski N,Kim SJ,Zaun D,Xiong H,Israni AK,Kasiske BL

更新日期：2016-02-01 00:00:00

abstract：:A patient with short gut syndrome presented with end-stage liver disease. She underwent an isolated liver transplantation at the age of 3.5 years. Parenteral nutrition was discontinued 1.5 years after surgery. At 7 years of age, the patient has maintained normal nutritional indices and growth while on a normal oral di...

journal_title：Transplantation

authors： Gottrand F,Michaud L,Bonnevalle M,Dubar G,Pruvot FR,Turck D

更新日期：1999-02-27 00:00:00

abstract：BACKGROUND:Administration of donor bone marrow (BM)-derived dendritic cell (DC) progenitors (DCp) that are major histocompatibility complex (MHC) class II+ but costimulatory molecule (CD40, CD80, CD86)-deficient can prolong mouse heart allograft survival This is associated with microchimerism and inhibition of antidono...

journal_title：Transplantation

authors： Lee WC,Zhong C,Qian S,Wan Y,Gauldie J,Mi Z,Robbins PD,Thomson AW,Lu L

更新日期：1998-12-27 00:00:00

abstract：BACKGROUND:Chronic cyclosporine (CsA) nephropathy, which has been unequivocally documented in recipients of heart, heart-lung, liver, or bone marrow transplants, as well as in nontransplant situations, usually results in a progressive deterioration of renal function. In this study, we assessed the potential reversibili...

journal_title：Transplantation

authors： Mourad G,Vela C,Ribstein J,Mimran A

更新日期：1998-03-15 00:00:00

abstract：BACKGROUND:The use of lung grafts from non-heart-beating donors (NHBD) is one way of solving the donor organ shortage problem. In this experiment, we studied the effect of retrograde flush (RF) from the left atrium before harvest, inhaled nitric oxide (NO), and gabexate mesilate (FOY), a protease inhibitor, in the lung...

journal_title：Transplantation

authors： Luh SP,Tsai CC,Shau WY,Chen JS,Kuo SH,Lin-Shiau SY,Lee YC

更新日期：2000-05-27 00:00:00

abstract：:Monocytes play a crucial role in the response of lymphocytes to phytomitogens. This role is evident during the very early events after exposure to the mitogen. Thus, significant lymphocyte transformation does occur when monocytes are removed from the culture within a few hours after exposure to mitogen, and the presen...

journal_title：Transplantation

authors： Mookerjee BK,Ballard J

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND:The objectives of this study are to investigate the impact of cytomegalovirus (CMV) donor (D)/recipient (R) serostatus on kidney transplant outcomes in recipients who received CMV prophylaxis and to investigate the association of individual antiviral agents (acyclovir, ganciclovir, and valganciclovir) with o...

journal_title：Transplantation

authors： Kuo HT,Ye X,Sampaio MS,Reddy P,Bunnapradist S

更新日期：2010-11-27 00:00:00

abstract：:Liver transplantation is currently the only established treatment of end-stage liver disease, but it is limited by a severe shortage of viable donor livers. Donors after cardiac death (DCD) are an untapped source that could significantly increase the pool of available livers. Preservation of these DCD livers by conven...

journal_title：Transplantation

authors： Tolboom H,Pouw RE,Izamis ML,Milwid JM,Sharma N,Soto-Gutierrez A,Nahmias Y,Uygun K,Berthiaume F,Yarmush ML

更新日期：2009-01-27 00:00:00

abstract：BACKGROUND:Matrix metalloproteinases (MMPs) play a key role in extracellular matrix remodeling events associated with hepatic regeneration after partial hepatectomy. We therefore hypothesized that urinary MMPs and their endogenous tissue inhibitors of matrix metalloproteinases (TIMPs) might also provide important infor...

journal_title：Transplantation

authors： Greene AK,Puder M,Roy R,Kilroy S,Louis G,Folkman J,Moses MA

更新日期：2004-10-27 00:00:00

abstract：BACKGROUND:CD200 delivers immunoregulatory signals following engagement of its receptor, CD200R. A family of CD200Rs (CD200R1-4) has been described. Spleen expresses cell surface CD200R1, while bone marrow shows predominantly expression of cell surface CD200R2/R3. We showed that dendritic cell precursors (DCp) cultured...

journal_title：Transplantation

authors： Gorczynski RM

更新日期：2006-04-15 00:00:00

abstract：BACKGROUND:We evaluated the importance and mechanism of graft and host accommodation in hamster-to-rat cardiac xenotransplantation models. METHODS:To evaluate graft accommodation, accommodated hamster grafts (Group 2) were transplanted to naïve host rats treated with FK506, and compared with naïve hamster grafts (Grou...

journal_title：Transplantation

authors： Komori K,Fuchimoto Y,Morikawa Y,Obara H,Kawachi S,Tanabe M,Hoshino K,Shimazu M,Matsuzaki Y,Kitajima M

更新日期：2008-01-15 00:00:00

abstract：BACKGROUND:We herein investigate critical ischemia times and the effect of novel preservation solutions such as new histidine-tryptophan-ketoglutarate (HTK-N) and TiProtec on the individual tissues of a rat limb isograft. METHODS:Orthotopic hind-limb transplantations were performed in male Lewis rats after 2 hours, 6 ...

journal_title：Transplantation

authors： Messner F,Hautz T,Blumer MJF,Bitsche M,Pechriggl EJ,Hermann M,Zelger B,Zelger B,Öfner D,Schneeberger S

更新日期：2017-09-01 00:00:00

abstract：:The pig has been considered unsuitable for experimental pancreatic transplantation. In order to develop a model for segmental transplantation, the vascular anatomy was studied in 41 pigs. No variation in venous drainage of the pancrease was found. In contrast, 3 variations of arterial supply were noted. In 29 of the p...

journal_title：Transplantation

authors： Shokouh-Amiri MH,Rahimi-Saber S,Andersen HO

更新日期：1989-01-01 00:00:00

abstract：:Glutathione and glyoxalase II levels were evaluated in cytosolic and mitochondrial compartments of rat liver after 7 and 24 hr of cold storage in University of Wisconsin (UW) and Euro-Collins solutions. 1-4 A similar time-dependent depletion of cytosolic glutathione up to about 60% of control values was observed in bo...

journal_title：Transplantation

authors： Jassem W,Ciarimboli C,Cerioni PN,Saba V,Norton SJ,Principato G

更新日期：1996-05-15 00:00:00

abstract：BACKGROUND:Abrupt temperature shift from hypothermia to normothermia incurred on reperfusion of organ grafts has been delineated as a genuine factor contributing to reperfusion injury and graft dysfunction after transplantation. METHODS:In a first clinical series of 6 patients, cold-stored livers, all allocated by the...

journal_title：Transplantation

authors： Hoyer DP,Mathé Z,Gallinat A,Canbay AC,Treckmann JW,Rauen U,Paul A,Minor T

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Operational tolerance is defined as long-term acceptance of a transplanted organ after complete cessation of immunosuppression (IS), but may not always protect against antigen-dependent changes in graft morphology. METHOD:IS free patients after living-donor liver transplantation (LDLT) underwent protocol bi...

journal_title：Transplantation

authors： Yoshitomi M,Koshiba T,Haga H,Li Y,Zhao X,Cheng D,Miyagawa A,Sakashita H,Tsuruyama T,Ohe H,Ueda M,Okamoto S,Egawa H,Wood K,Sakaguchi S,Manabe T,Tanaka K,Uemoto S

更新日期：2009-02-27 00:00:00

abstract：:Monocytes from human peripheral blood, when incubated in vitro, spread onto the surface of the glass. Horse antihuman lymphocyte globulin (ALG) added to the incubation chamber inhibits the spreading, while normal horse globulin (NHG) does not. The inhibition depends on the concentration of ALG admixed to the mononucle...

journal_title：Transplantation

authors： Silobrcić V,Mazuran R,Dekaris D,Balner H

更新日期：1976-01-01 00:00:00

abstract：:Graft rejection remains an important cause of renal allograft failure, despite improvements in immunosuppression and HLA typing. Although HLA matching is beneficial, ensuring an exact match it is often impractical. Thus, a reliable in vitro method for quantitating and qualitating alloreactivity is an important goal. I...

journal_title：Transplantation

authors： Kaminski ER,Kaminski A,Bending MR,Chang R,Heads A,Szydlo RM,Pereira RS

更新日期：1995-10-15 00:00:00

abstract：:The effect of the spleen cells and thymus cells from Corynebacterium liquefaciens-treated (C57BL/6 x BALB/c)F1 hybrid mice on graft-versus-host (GVH) reaction, initiated in the parental to newborn F1 hybrid strain combination, was studied by using Simonsen's spleen assay. The combined inocula of 5 x 10(6) normal BALB/...

journal_title：Transplantation

authors： Kobayashi M,Kawashima K,Yamada K

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND:In previous studies of cynomolgus monkey lung allograft recipients, we demonstrated significant immunosuppressive efficacy but reduced tolerability after combined treatment with high doses of microemulsion cyclosporine (CsA) and SDZ RAD (40-O-(2-hydroxyethyl)-rapamycin). The current study was designed to com...

journal_title：Transplantation

authors： Hausen B,Gummert J,Berry GJ,Christians U,Serkova N,Ikonen T,Hook L,Legay F,Schuler W,Schreier MH,Morris RE

更新日期：2000-02-27 00:00:00

abstract：:We report the successful application of a hybrid artificial pancreas device for the treatment of severe diabetes mellitus induced by total pancreatectomy in two dogs. Control of the blood sugar was achieved for more than 1 year in these two animals without any immunosuppressive therapy. Although exogenous insulin was ...

journal_title：Transplantation

authors： Maki T,Lodge JP,Carretta M,Ohzato H,Borland KM,Sullivan SJ,Staruk J,Muller TE,Solomon BA,Chick WL

更新日期：1993-04-01 00:00:00

abstract：:The effect of the graft-versus-host reaction in response to minor histocompatibility antigens on the antibody response to a T-dependent antigen was studied in four strains of mice. Lethally irradiated mice were transplanted with bone marrow plus graded numbers of spleen cells from H-2-compatible donors. Recipients of ...

journal_title：Transplantation

authors： Hamilton BL,Ochs HD

更新日期：1989-06-01 00:00:00

abstract：:Extrinsic denervation and lymphatic disruption impair nutrient absorption after small bowel transplantation. The present study was undertaken to determine whether adding the ileocecal valve with or without the ascending colon would improve the function of a segmental intestinal graft. Five groups of Lewis rats (n = 10...

journal_title：Transplantation

authors： Black RT,Hashimoto T,Zhong RZ,Behme RJ,Garcia BM,Duff JH,Grant DR

更新日期：1994-04-15 00:00:00

abstract：:Single lung isografting in rats with pulmonary hypertension has been reported. However, it is hard to evaluate cardiopulmonary hemodynamics accurately or to use circulatory assists during procedures using rats. Therefore, we tried to establish a model of pulmonary hypertension in the beagle. Twenty young beagles were ...

journal_title：Transplantation

authors： Okada M,Yamashita C,Okada M,Okada K

更新日期：1995-07-15 00:00:00

abstract：BACKGROUND:HLA-G is a nonclassical MHC class I molecule and its physiological expression restricted to placental extravillous trophoblasts contributes to maternal tolerance to the semiallogeneic fetus. Aberrant expression of HLA-G in human organ grafts has been proposed to contribute to graft acceptance. METHODS:We st...

journal_title：Transplantation

authors： Moroso V,van Cranenbroek B,Mancham S,Sideras K,Boor PP,Biermann K,de Vogel L,de Knegt RJ,van der Eijk A,van der Laan LJ,de Jonge J,Metselaar HJ,Joosten I,Kwekkeboom J

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Cardiac allograft vasculopathy (CAV) has an incidence of 43% at 8 years after heart transplantation with extremely limited treatment options and unclear pathogenesis. CAV constitutes a significant complication that limits the long-term survival of heart recipients. Insulin-like growth factor-1 (IGF-1) is ass...

journal_title：Transplantation

authors： Aharinejad S,Salama M,Rödler S,Ehrlich M,Zuckermann A,Laufer G

更新日期：2012-02-15 00:00:00

abstract：BACKGROUND:The leflunomide analog, FK778, is a selective pyrimidine synthesis inhibitor. In rodent models, FK778 is efficacious in the prevention of allograft and xenograft rejection, and a combination of FK778 and cyclosporine has synergistic immunosuppressive efficacy. METHODS:Heterotopic renal transplantation was p...

journal_title：Transplantation

authors： Kyles AE,Gregory CR,Griffey SM,Bernsteen L,Pierce J,Lilja HS,Morris RE

更新日期：2003-04-27 00:00:00