Transplantation of segmental rat intestinal grafts including the ileocecal value and the ascending colon.

abstract：BACKGROUND:Human cytomegalovirus (HCMV) infection is associated with allograft vasculopathy and rejection. One potential mechanism is vascular injury from immunologically mediated processes. HCMV infection has been shown to increase the constitutive expression of intercellular adhesion molecule-1 (ICAM-1). The objectiv...

journal_title：Transplantation

authors： Burns LJ,Pooley JC,Walsh DJ,Vercellotti GM,Weber ML,Kovacs A

更新日期：1999-01-15 00:00:00

abstract：BACKGROUND:BK virus-associated nephropathy (BKVN) is associated with an increased risk of graft failure. METHODS:Levels of mRNAs encoding proteins implicated in inflammation and fibrosis were measured in urine collected at the time of biopsy diagnosis of BKVN in 29 kidney graft recipients and analyzed for prognosticat...

journal_title：Transplantation

authors： Dadhania D,Snopkowski C,Muthukumar T,Lee J,Ding R,Sharma VK,Christos P,Bang H,Kapur S,Seshan SV,Suthanthiran M

更新日期：2013-07-27 00:00:00

abstract：BACKGROUND:The aim of this article is to report our experience regarding the survival and the evolution of polyneuropathy of the extremities and autonomic dysfunction in 18 liver transplant patients with familial amyloidotic polyneuropathy type I after a mean follow-up of more than 2.5 years for 13 patients. METHODS:T...

journal_title：Transplantation

authors： Parrilla P,Ramirez P,Andreu LF,Bueno SF,Robles R,Miras M,Acosta F,Viader-Farre D,de Mingo P,Bermejo J,Garrido SF,Munar-Ques M

更新日期：1997-08-27 00:00:00

abstract：BACKGROUND:Early enteral nutrition with solutions containing prebiotics (fiber) and probiotics (Lactobacillus) is suggested to reduce bacterial translocation and minimize the incidence of infections after liver transplantation. METHODS:In a prospective, randomized placebo-controlled trial consisting of 95 patients, we...

journal_title：Transplantation

authors： Rayes N,Seehofer D,Hansen S,Boucsein K,Müller AR,Serke S,Bengmark S,Neuhaus P

更新日期：2002-07-15 00:00:00

abstract：:Israel's rates of organ donation have been one of the lowest among developed countries. An attempt to change this has led to the introduction of a pioneering new law, the Organ Transplant Act 2008, which came into effect in January 2010 and sets out principles underlying a new policy in relation to the allocation of o...

journal_title：Transplantation

authors： Quigley M,Wright L,Ravitsky V

更新日期：2012-05-27 00:00:00

abstract：:The effect of cyclosporine on lymphocyte intracellular free calcium [( Ca2+]i) is controversial, and potential age-related differences in lymphocyte CsA sensitivity have not been studied. We measured the mitogen-induced change in [Ca2+]i in peripheral blood lymphocytes (PBLs) following intravenous CsA infusion (5 mg/k...

journal_title：Transplantation

authors： Tsao PW,Diaz RJ,Radde IC,Wong PY,Martell MF,Augustine JM,Wilson GJ,Coles JG

更新日期：1991-08-01 00:00:00

abstract：:Immunosuppressive therapy increases the risk of recurrence of initial cancers in organ transplant patients, and compelling therapeutic protocols are needed to suppress the malignancy and protect the allograft. We examined the potential use of 15-deoxyspergualin (DSG) in relation to organ transplantation and cancer. Th...

journal_title：Transplantation

authors： Ohsawa I,Uemoto S,Kobayashi E,Murakami T

更新日期：2007-08-15 00:00:00

abstract：:A 22-year-old previously nonsensitized female patient (HLA-A2,28; B7,14; DR1,2) received a kidney from her HLA-identical brother. She irreversibly rejected the graft 2 1/2 weeks later. In vitro tests performed 6 weeks after the graft loss, using recipient responding and donor-stimulating and target cells, revealed a w...

journal_title：Transplantation

authors： Pfeffer PF,Thorsby E

更新日期：1982-01-01 00:00:00

abstract：:Multiple variations of the basic lymphocytotoxicity test have been reported to increase test sensitivity. Although these modifications are used routinely in crossmatch tests, as required by federal regulation, there has been no methodical assessment of the relative sensitivities and specificities of these techniques w...

journal_title：Transplantation

authors： Zachary AA,Klingman L,Thorne N,Smerglia AR,Teresi GA

更新日期：1995-09-15 00:00:00

abstract：BACKGROUND:More than 30% of potential kidney transplant recipients have pre-existing anti-human leukocyte antigen antibodies. This subgroup has significantly lower transplant rates and increased mortality. Desensitization has become an important tool to overcome this immunological barrier. However, limited data is avai...

journal_title：Transplantation

authors： Riella LV,Safa K,Yagan J,Lee B,Azzi J,Najafian N,Abdi R,Milford E,Mah H,Gabardi S,Malek S,Tullius SG,Magee C,Chandraker A

更新日期：2014-06-27 00:00:00

abstract：:By using the lysostrip and the blocking of cytotoxicity by Fab2 fragments, HLA-A and B antibodies were detected in sera from rabbits and goats immunized with human high-density lipoprotein (HDL)-associated HLA antigens isolated from sera and from cultured lymphoid cells. After appropriate absorptions, the xenoantisera...

journal_title：Transplantation

authors： Richiardi P,Pellegrino MA,Ferrone S

更新日期：1979-10-01 00:00:00

abstract：:DA rats treated with cyclosporine for 2 weeks after being grafted with an RT1-incompatible PVG heart graft did not reject the graft and developed a state of specific unresponsiveness to graft antigens. The cellular mechanisms maintaining this state of unresponsiveness were studied by testing the capacity of lymphocyte...

journal_title：Transplantation

authors： Hall BM,Jelbart ME,Dorsch SE

更新日期：1984-06-01 00:00:00

abstract：:Spontaneous rupture of the liver has been described in association with many benign and malignant conditions. We report, to our knowledge, the first case of spontaneous rupture of the liver upon revascularization, requiring total hepatectomy and portocaval shunt, followed by successful retransplantation. Routine patho...

journal_title：Transplantation

authors： Mistry BM,Solomon H,Garvin PJ,Durham RM,Turnage S,Bacon BR,Galvin N,Varma CR

更新日期：2000-05-27 00:00:00

abstract：:Since 1989, the U.S. Food and Drug Administration (FDA) has encouraged the study of new drug and therapeutic products in elderly patients. However, despite the aging population in the United States, elderly patients continue to be underrepresented in clinical trials across a variety of therapeutic areas, including tra...

journal_title：Transplantation

authors： Meyer JM,Archdeacon P,Albrecht R

更新日期：2013-04-15 00:00:00

abstract：:Anti-CD3 mAbs are potent inhibitors of T cell function; however, administration of mitogenic mAb can cause significant morbidity secondary to T cell activation and cytokine release. Nonmitogenic anti-CD3 mAb is immunosuppressive in mice without inducing detectable morbidity, and may thus be preferable for in vivo T ce...

journal_title：Transplantation

authors： Sawchuk SS,Gates R,Hirsch R

更新日期：1995-12-15 00:00:00

abstract：BACKGROUND:Organ scarcity continues in solid organ transplantation, such that the availability of organs limits the number of people able to benefit from transplantation. Medical advancements in managing end-stage organ disease have led to an increasing demand for multiorgan transplant, wherein a patient with multiorga...

journal_title：Transplantation

authors： Cheng XS,Goldhaber-Fiebert J,Tan JC,Chertow GM,Kim WR,Wall AE

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Natural antibodies that bind the carbohydrate antigen Galalpha1-3Galbeta1-4GlcNAc-R (alphaGal) mediate rigorous rejection of porcine xenografts and represent a major immunological hurdle to successful discordant xenotransplantation. However, little is known about how production of antibodies specific for alp...

journal_title：Transplantation

authors： Cretin N,Iacomini J

更新日期：2002-05-27 00:00:00

abstract：BACKGROUND:Primary hyperoxaluria type-1 (PH1) is an autosomal recessive disease characterized by excessive oxalate production by hepatocytes caused by the deficiency of peroxisomal alanine-glyoxylate aminotransferase (AGT) activity. Persistent hyperoxaluria causes nephrocalcinosis and urolithiasis, leading to renal fai...

journal_title：Transplantation

authors： Jiang J,Salido EC,Guha C,Wang X,Moitra R,Liu L,Roy-Chowdhury J,Roy-Chowdhury N

更新日期：2008-05-15 00:00:00

abstract：BACKGROUND:The purpose of this study is to examine the effects of the coronavirus disease 2019 (COVID-19) pandemic on adult lung transplants and report practice changes in the United States. METHODS:A retrospective analysis of a public dataset from the United Network for Organ Sharing was performed regarding adult lun...

journal_title：Transplantation

authors： Chan EG,Chan PG,Harano T,Ryan JP,Morrell MR,Sanchez PG

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:The potential risk of transmission of porcine endogenous retroviruses (PERV) from xenogeneic donors into humans has been widely debated. Because we were involved in a phase I/II clinical trial using a bioartificial liver support system (BLSS), we proceeded to evaluate the biosafety of this device. MATERIALS...

journal_title：Transplantation

authors： Kuddus R,Patzer JF 2nd,Lopez R,Mazariegos GV,Meighen B,Kramer DJ,Rao AS

更新日期：2002-02-15 00:00:00

abstract：:Crigler-Najjar type 1 disease (CNS1) is the result of a genetic defect, leading to complete functional loss of an enzyme which glucuronidates bilirubin. As a consequence, unconjugated bilirubin accumulates and may cause kernicterus, the most serious complication in adolescents. Phototherapy effectively adjusts bilirub...

journal_title：Transplantation

authors： Schauer R,Lang T,Zimmermann A,Stangl M,Da Silva L,Schildberg FW,Rau HG

更新日期：2002-01-15 00:00:00

abstract：:Invasive aspergillosis and mucormycosis are life-threatening infections in solid organ and hematopoietic cell transplant recipients. Despite medical advancements in the care of these patients and the availability of new mold-active drugs, the outcomes remain suboptimal. Therefore, there has been increased interest in ...

journal_title：Transplantation

authors： Haidar G,Singh N

更新日期：2018-11-01 00:00:00

abstract：:A quantitative absorption-blocking assay was used to measure the levels of antibody in immune rabbit sera that react with the serologically defined HLA molecular complex on the cell surface. Quantitation was determined by comparing the number of xenoantibody-treated cells with the number of untreated control cells nee...

journal_title：Transplantation

authors： Wilson LA,Gallaspy GT

更新日期：1978-07-01 00:00:00

abstract：:Two infants born to mothers who had been given a renal transplant and who were receiving azathioprine and prednisone have been followed up for over 2 years. Initially both had lower than normal lymphocyte counts and cortisol levels. Chromosomal aberrations similar to those found in the lymphocytes of the mothers were ...

journal_title：Transplantation

authors： Price HV,Salaman JR,Laurence KM,Langmaid H

更新日期：1976-04-01 00:00:00

abstract：BACKGROUND:Circulation of leukocytes via blood, tissue and lymph is integral to adaptive immunity. Afferent lymphatics form CCL21 gradients to guide dendritic cells and T cells to lymphatics and then to draining lymph nodes (dLN). Vascular endothelial growth factor C and vascular endothelial growth factor receptor 3 (V...

journal_title：Transplantation

authors： Iwami D,Brinkman CC,Bromberg JS

更新日期：2015-04-01 00:00:00

abstract：:The mortality rates for CVDs in transplant recipients are greater than those in the general population (13). CVDs are a major cause of both patient and graft loss in renal transplant recipients, and improving cardiovascular health may help to extend both patient and graft survival. A complication of chronic renal fail...

journal_title：Transplantation

authors： Wheeler DC,Steiger J

更新日期：2000-12-15 00:00:00

abstract：:Progressive microvascular endothelial damage is a characteristic feature of fulminant acute cardiac allograft rejection in the rat. Serial ultrastructural tracer studies using i.v. administered colloidal carbon and horseradish peroxidase have been performed in an adoptive transfer model to determine the role of cellul...

journal_title：Transplantation

authors： Lowry RP,Forbes RD

更新日期：1984-02-01 00:00:00

abstract：BACKGROUND:Posttransplant diabetes mellitus (PTDM) is a frequent complication in renal-transplant recipients (RTRs). We conducted a prospective study to assess the potential role of PTDM in the development of atherosclerotic events (AE) in RTRs. METHODS:Three hundred fifty-seven consecutive RTRs were enrolled in this ...

journal_title：Transplantation

authors： Ducloux D,Kazory A,Chalopin JM

更新日期：2005-02-27 00:00:00

abstract：:Pregnancy after solid organ transplantation, although considered high risk for maternal, fetal, and neonatal complications, has been quite successful. Tacrolimus pharmacokinetic changes during pregnancy make interpretation of whole blood trough concentrations particularly challenging. There are multiple factors that c...

journal_title：Transplantation

authors： Hebert MF,Zheng S,Hays K,Shen DD,Davis CL,Umans JG,Miodovnik M,Thummel KE,Easterling TR

更新日期：2013-04-15 00:00:00

abstract：BACKGROUND:Since 1995, dual-kidney transplantation using organs from marginal donors has been used at our center to expand the organ donor pool and decrease the waiting time for deceased donor kidney transplantation. This approach has allowed for a shorter waiting period without compromising outcome in the early posttr...

journal_title：Transplantation

authors： Tan JC,Alfrey EJ,Dafoe DC,Millan MT,Scandling JD

更新日期：2004-09-15 00:00:00