Long-term results of liver transplantation in familial amyloidotic polyneuropathy type I.

Abstract:

BACKGROUND:The aim of this article is to report our experience regarding the survival and the evolution of polyneuropathy of the extremities and autonomic dysfunction in 18 liver transplant patients with familial amyloidotic polyneuropathy type I after a mean follow-up of more than 2.5 years for 13 patients. METHODS:The actuarial survival rate of the 18 patients is 72.2% and 60.1%, respectively, at 12 and 58 months. RESULTS:In all the patients we noted clinical improvement of the polyneuropathy of the extremities and autonomic dysfunction during the first 6 months after transplant. The clinical data due to autonomic nervous system involvement showed an earlier improvement than those due to nervous motor involvement. CONCLUSIONS:In conclusion, our results suggest that liver transplant may be useful in the treatment of certain cases of familial amyloidotic polyneuropathy to stop the neurological deterioration of the patients and to avoid the fatal end of the disease.

journal_name

Transplantation

journal_title

Transplantation

authors

Parrilla P,Ramirez P,Andreu LF,Bueno SF,Robles R,Miras M,Acosta F,Viader-Farre D,de Mingo P,Bermejo J,Garrido SF,Munar-Ques M

doi

10.1097/00007890-199708270-00017

subject

Has Abstract

pub_date

1997-08-27 00:00:00

pages

646-9

issue

4

eissn

0041-1337

issn

1534-6080

journal_volume

64

pub_type

杂志文章
  • Corneal Stromal Transplantation With Human-derived Acellular Dermal Matrix for Pellucid Marginal Corneal Degeneration: A Nonrandomized Clinical Trial.

    abstract:BACKGROUND:To investigate the transparency, biocompatibility, and safety of human-derived acellular dermal matrix for application in corneal stromal transplantation. METHODS:Twenty-four patients (24 eyes) with pellucid marginal corneal degeneration were enrolled, and intrastromal keratoplasty was performed with human-...

    journal_title:Transplantation

    pub_type: 临床试验,杂志文章

    doi:10.1097/TP.0000000000002681

    authors: Jiang X,Wang Y,Qiu W,Huang C,Liu Z,Ding T,Shi D,Li X

    更新日期:2019-06-01 00:00:00

  • Proliferative alloresponse of T cytotoxic cells identifies rejection-prone children with small bowel transplantation.

    abstract:BACKGROUND:More than 60% children with small bowel transplantation (SBTx) experience acute cellular rejection. PURPOSE/METHODS:To identify children at risk of rejection, donor- and third-party-induced proliferation of T-helper and T cytotoxic (Tc) cells, and their naïve and memory (M) subsets was evaluated simultaneou...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/TP.0b013e3181d98c0f

    authors: Ashokkumar C,Gupta A,Sun Q,Higgs BW,Ningappa M,Snyder S,Johnson M,Mazariegos G,Soltys K,Bond G,Abu-Elmagd K,Sindhi R

    更新日期:2010-06-15 00:00:00

  • Effect of Institutional Case Volume on In-hospital Mortality After Living Donor Liver Transplantation: Analysis of 7073 Cases Between 2007 and 2016 in Korea.

    abstract:BACKGROUND:The relationship between institutional case volume and clinical outcomes after living donor liver transplantation is not clarified. METHODS:We conducted a nationwide retrospective cohort study using the database of Korean National Healthcare Insurance Service. Between January 2007 and December 2016, 7073 ad...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/TP.0000000000002394

    authors: Yoo S,Jang EJ,Yi NJ,Kim GH,Kim DH,Lee H,Jung CW,Ryu HG

    更新日期:2019-05-01 00:00:00

  • Xenoantibody directed against molecular components of the HLA system. Quantitation of antibody to serologically defined HLA complexes on the cell surface.

    abstract::A quantitative absorption-blocking assay was used to measure the levels of antibody in immune rabbit sera that react with the serologically defined HLA molecular complex on the cell surface. Quantitation was determined by comparing the number of xenoantibody-treated cells with the number of untreated control cells nee...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/00007890-197807010-00009

    authors: Wilson LA,Gallaspy GT

    更新日期:1978-07-01 00:00:00

  • Time-response studies of the cellular immune response to cell membrane antigens.

    abstract::It was the objective of these experiments to study the time-related changes in the responsiveness of the cellular elements of the immune system following contact with single non-H-2 or multiple H-2 histocompatibility antigens. The reactivity of spleen cells from mice that received injections of spleen cells bearing H-...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/00007890-198802000-00047

    authors: Graff RJ,Kurtz ME,Russell H,Martin-Morgan D

    更新日期:1988-02-01 00:00:00

  • Natural Killer Cells: Critical Effectors During Antibody-mediated Rejection of Solid Organ Allografts.

    abstract::Antibody-mediated rejection (AMR) is an important cause of graft loss and continues to present a formidable obstacle to successful transplantation. Unresolved problems continue to be the absence of effective strategies to ablate the donor-specific antibody (DSA) response as well as to attenuate the antibody-mediated g...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/TP.0000000000003298

    authors: Miyairi S,Baldwin WM 3rd,Valujskikh A,Fairchild RL

    更新日期:2021-02-01 00:00:00

  • Nutritional markers in liver allograft recipients.

    abstract:BACKGROUND:Malnutrition is common in patients with end-stage liver disease considered for transplantation, but it is unclear whether this affects the outcome after transplantation. AIM.: To determine whether the severity of malnutrition in liver transplant candidates affects outcome after transplantation. METHODS:We d...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/01.tp.0000150022.64564.c2

    authors: Shahid M,Johnson J,Nightingale P,Neuberger J

    更新日期:2005-02-15 00:00:00

  • Patterns and Predictors of Mortality After Waitlist Dropout of Patients With Hepatocellular Carcinoma Awaiting Liver Transplantation.

    abstract:BACKGROUND:There is a lack of information about survival after dropout from the liver transplant waiting list. Therefore, we aimed to assess the overall survival, and risk factors for death, after waiting list dropout due to hepatocellular carcinoma (HCC) progression. METHODS:We assessed patients who dropped out of th...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/TP.0000000000002616

    authors: Gorgen A,Rosales R,Sadler E,Beecroft R,Knox J,Dawson LA,Ghanekar A,Grant D,Greig PD,Sapisochin G

    更新日期:2019-10-01 00:00:00

  • Long-term prognosis of renal transplantation after preemptive treatment of cytomegalovirus infection.

    abstract::A role for cytomegalovirus (CMV) infection in the etiologies of acute and chronic rejection in renal allograft recipients has been suggested. We previously reported that preemptive treatment of CMV infection with ganciclovir in kidney transplant patients was safe and effective. We now present a retrospective analysis ...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/00007890-199704150-00012

    authors: Akposso K,Rondeau E,Haymann JP,Peraldi MN,Marlin C,Sraer JD

    更新日期:1997-04-15 00:00:00

  • Prolongation of rat kidney allograft survival by nematodes.

    abstract::Nippostrongylus infection strongly stimulates TH2 activity in vivo. Given the evidence of cross regulation between TH2 and TH1 cells, and the link between TH1 activity and graft rejection, we examined the effects of Nippostrongylus infection on the fate of kidney allografts in rats. Both prior Nippostrongylus infectio...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/00007890-199601270-00003

    authors: Ledingham DL,McAlister VC,Ehigiator HN,Giacomantonio C,Theal M,Lee TD

    更新日期:1996-01-27 00:00:00

  • Increased infections in liver transplant recipients with recurrent hepatitis C virus hepatitis.

    abstract::Infectious complications in patients with recurrent hepatitis C virus (HCV) hepatitis after liver transplantation were prospectively assessed and compared with those of all other liver transplant recipients without HCV hepatitis operated on during the same period. Major infections occurred in 64% (14/22) of the patien...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/00007890-199602150-00014

    authors: Singh N,Gayowski T,Wagener MM,Marino IR

    更新日期:1996-02-15 00:00:00

  • Xenoantisera to allotypic specificities of HLA-A and B antigens. Serological characterization.

    abstract::By using the lysostrip and the blocking of cytotoxicity by Fab2 fragments, HLA-A and B antibodies were detected in sera from rabbits and goats immunized with human high-density lipoprotein (HDL)-associated HLA antigens isolated from sera and from cultured lymphoid cells. After appropriate absorptions, the xenoantisera...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/00007890-197910000-00014

    authors: Richiardi P,Pellegrino MA,Ferrone S

    更新日期:1979-10-01 00:00:00

  • Phenotypic variations in resting and activated levels of ICAM-1 expression by cultured human aortic endothelial cells.

    abstract::ICAM-1 is an inducible glycoprotein important in the adhesion, activation, and transmigration of circulating leukocytes across the vascular endothelial monolayer, and it likely plays a key role in the allogeneic response. To determine the reproducibility and significance of variations in resting levels of cell surface...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/00007890-199410270-00015

    authors: Everett JP,Shipley GD,Mauck KA,Wagner CR,Morris TE,Hosenpud JD

    更新日期:1994-10-27 00:00:00

  • Cytokine pattern during rejection and infection after liver transplantation--improvements in postoperative monitoring?

    abstract::Despite improvements in immunosuppression, rejection occurs in 50% of liver transplant patients and may cause significant morbidity. The most frequent cause of death after liver transplantation is severe infection. Determination of the cytokine network may lead to earlier detection of patients at risk for severe rejec...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/00007890-199611270-00011

    authors: Platz KP,Mueller AR,Rossaint R,Steinmüller T,Lemmens HP,Lobeck H,Neuhaus P

    更新日期:1996-11-27 00:00:00

  • Activation of HMGB1-TLR4 Pathway and Inflammasome Contribute to Enhanced Inflammatory Response in Extended Criteria and Kidneys With KDPI ≥85.

    abstract:BACKGROUND:Metrics for evaluating low-quality kidneys have failed to predict outcomes or reduce the kidney refusal and discard rates. Kidneys from extended-criteria donors (ECDs) and kidneys with ≥85% kidney donor profile indexes (KDPIs) might have different sensitivities to the proinflammatory milieu generated by brai...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/TP.0000000000003048

    authors: Florim GMS,Caldas HC,Gonçalves NN,Bueno GOBE,Baptista MASF,Fernandes-Charpiot IMM,Abbud-Filho M

    更新日期:2020-04-01 00:00:00

  • Flush solution 2, a new concept for one-to-three-day hypothermic renal storage preservation. Functional recovery after preservation in Euro-Collins, Collins' C2, hypertonic citrate, and F.2 solution.

    abstract::Experiments were performed on the quality of renal functional recovery after 24, 48, or 72-hr hypothermic storage preservation of canine kidneys in Euro-Collins solution (EC), Collins' solution C2, hypertonic citrate solutions (HC, HC-D2O), or our new flush solution 2 (F.2). Clearance tests (inulin, paraaminohippuric ...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/00007890-198502000-00003

    authors: Fischer JH,Knupfer P,Beyer M

    更新日期:1985-02-01 00:00:00

  • Prolonged allogeneic marrow engraftment following nonmyeloablative conditioning using 100 cGy total body irradiation and pentostatin before and pharmacological immunosuppression after transplantation.

    abstract::In a canine model of dog leukocyte antigen (DLA)-identical nonmyeloablative marrow transplantation including postgrafting immunosuppression with cyclosporine (CSP) and mycophenolate mofetil (MMF), engraftment was only transient with 100 cGy total body irradiation (TBI) conditioning, indicating suboptimal pretransplant...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/01.tp.0000181168.42461.0b

    authors: Panse JP,Storb R,Storer B,Santos EB,Wentzel C,Sandmaier BM

    更新日期:2005-11-27 00:00:00

  • The effect of agents which modulate levels of the cyclic nucleotides on human lymphotoxin secretion and activity in vitro.

    abstract::The ability of concanavalin-A (Con-A) to activate lymphocytes to secrete human lymphotoxin (LT) was tested in the presence of agents known to modify the intracellular levels of cyclic nucleotides (cAMP and cGMP). Lymphocytes were treated with these agents at different stages of activation: (1) during the first encount...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/00007890-197510000-00010

    authors: Prieur AM,Granger GA

    更新日期:1975-10-01 00:00:00

  • First in man renal transplantation after ex vivo normothermic perfusion.

    abstract:BACKGROUND:Normothermic perfusion is an alternative but little studied method of organ preservation. Herein, we report the first case of ex vivo normothermic renal transplant perfusion in man. METHODS:The 62-year-old extended criteria donor died of an intracranial hemorrhage and had undergone cardiopulmonary resuscita...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/TP.0b013e31822d4e04

    authors: Hosgood SA,Nicholson ML

    更新日期:2011-10-15 00:00:00

  • Pharmacokinetic Study of Conversion Between 2 Formulations of Once-daily Extended-release Tacrolimus in Stable Lung Transplant Patients.

    abstract:BACKGROUND:The aim of this study was to compare the pharmacokinetic profile, tolerability, and safety of a novel once-daily extended-release formulation of tacrolimus (LCPT) with that of once-daily prolonged-release tacrolimus (ODT) in stable adult lung transplant (LT) recipients. METHODS:Phase II, open-label, single-...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/TP.0000000000002348

    authors: Sintes H,Sáez-Giménez B,Berastegui C,López-Meseguer M,Monforte V,Bravo C,Vima J,Gómez-Ollés S,Roman A

    更新日期:2018-10-01 00:00:00

  • Reduced dose rabbit anti-thymocyte globulin induction for prevention of acute rejection in high-risk kidney transplant recipients.

    abstract:BACKGROUND:Despite the prevalent use of rabbit antithymocyte globulin (rATG) as an induction agent in kidney transplantation, the appropriate dose for preventing acute rejection in high-risk patients is not known. Few studies have examined total exposure of rATG less than 6 mg/kg, with fewer studies examining lower dos...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/TP.0b013e3181b6f38c

    authors: Klem P,Cooper JE,Weiss AS,Gralla J,Owen P,Chan L,Wiseman AC

    更新日期:2009-10-15 00:00:00

  • Current status of clinical islet transplantation.

    abstract::Islet transplantation is currently being explored as a treatment for patients with type 1 diabetes. At present, the number of patients becoming insulin-independent is rapidly increasing world-wide applying the transplantation protocol originally described by the group in Edmonton. A hallmark in this procedure is repea...

    journal_title:Transplantation

    pub_type: 杂志文章,评审

    doi:10.1097/01.tp.0000157273.60147.7c

    authors: Korsgren O,Nilsson B,Berne C,Felldin M,Foss A,Kallen R,Lundgren T,Salmela K,Tibell A,Tufveson G

    更新日期:2005-05-27 00:00:00

  • Recipient-reactive antibodies occur during development of acute graft-versus-host reaction after small bowel transplantation.

    abstract::After small bowel transplantation, not only rejection but also graft-versus-host reaction (GVHR) may occur. Donor T lymphocytes, transferred together with the graft, are a prerequisite for the development of GVHR. So far, however, little is known about the effector mechanisms in acute GVHR. It can be assumed that not ...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/00007890-199608150-00007

    authors: Johnsson C,Bengtsson M,Tufveson G

    更新日期:1996-08-15 00:00:00

  • Impact of extracorporeal membrane oxygenation or mechanical ventilation as bridge to combined heart-lung transplantation on short-term and long-term survival.

    abstract:BACKGROUND:Extracorporeal membrane oxygenation (ECMO) and mechanical ventilation (MV) can be used as a bridge to heart-lung transplantation (HLT). The goal of this study was to determine if pretransplantation ECMO or MV affects survival in HLT. METHODS:The United Network for Organ Sharing database was reviewed for all...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/TP.0b013e3182a860b8

    authors: Jayarajan SN,Taghavi S,Komaroff E,Brann S,Horai T,Cordova F,Patel N,Guy TS,Toyoda Y

    更新日期:2014-01-15 00:00:00

  • Increased QT dispersion in hemodialysis patients improve after renal transplantation: a prospective-controlled study.

    abstract::Increased QT dispersion (QTd), predicting patients with risk of malignant arrhythmia, have recently been reported in hemodialysis patients (HDp). In this prospective study, we aimed to investigate changes in QTd and signal averaged-ECG (SAECG) in HDp after transplantation. Twenty-seven HDp (M/F:18/9, mean age 30+/-8 y...

    journal_title:Transplantation

    pub_type: 临床试验,杂志文章

    doi:10.1097/00007890-200111150-00009

    authors: Yildiz A,Akkaya V,Tükek T,Sahin S,Sever MS,Bozfakioğlu S,Korkut F

    更新日期:2001-11-15 00:00:00

  • Spontaneous reestablishment of self-tolerance in BB/Pfd rats.

    abstract::We describe a substrain of BB rats, BB/Pfd, characterized by a loss of autoimmune potential soon after onset of diabetes. When fresh syngeneic (BB/Pfd) islets (6 islets/g body weight) were transplanted under the kidney capsule of diabetic BB/Pfd rats 1-2 weeks after diabetes onset (n = 14), no recurrence of diabetes o...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:

    authors: Mathieu C,Kuttler B,Waer M,Bouillon R,Hahn HJ

    更新日期:1994-08-15 00:00:00

  • Switch from calcineurin inhibitors to sirolimus-induced renal recovery in heart transplant recipients in the midterm follow-up.

    abstract:BACKGROUND:Calcineurin inhibitor (CI)-based immunosuppression has prolonged the survival of heart transplant recipients. However, CI-induced renal injury remains as a major problem in these patients. Sirolimus is an immunosuppressant with no significant impact on renal function. A limited number of recent papers have s...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/01.tp.0000177644.45192.a3

    authors: Bestetti R,Theodoropoulos TA,Burdmann EA,Filho MA,Cordeiro JA,Villafanha D

    更新日期:2006-03-15 00:00:00

  • The effects of pretransplant cyclosporine therapy on rats grafted with twelve-hour cold-stored livers--with special reference to reperfusion injury.

    abstract::The effect of pretreatment with cyclosporine on liver preservation was studied using a rat liver transplant model. In a preliminary 1-week survival study, 59 liver transplants were performed. In group A, neither donors nor recipients were treated. In group B, the recipients were pretreated by a 3-day course of CsA (10...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/00007890-199110000-00007

    authors: Goto S,Kim YI,Shimada T,Kawano K,Kobayashi M

    更新日期:1991-10-01 00:00:00

  • Atrial anastomotic thrombus causes neurologic deficits in a lung transplant recipient.

    abstract::Pulmonary thrombus formation in the region of atrial anastomosis following lung transplantation has been reported by several authors. Such patients typically present immediately after surgery with significant hemodynamic compromise causing pulmonary edema and hypoxemia. We describe a patient who presented with bilater...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/00007890-199609150-00028

    authors: Stang MR,Hinderliter AL,Gott KK,Paradowski LJ,Aris RM

    更新日期:1996-09-15 00:00:00

  • Transplantation of canine lung allografts preserved in UW solution for 24 hours.

    abstract::To evaluate the efficacy of University of Wisconsin (UW) solution for lung preservation, we performed canine lung allotransplantation with lungs preserved in UW solution. Donor lungs from eight dogs were flushed with UW solution and lungs from four dogs with Euro-Collins solution, and these were preserved for 24 hr in...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/00007890-199301000-00004

    authors: Kawahara K,Itoyanagi N,Takahashi T,Akamine S,Kobayashi M,Tomota M

    更新日期:1993-01-01 00:00:00