Apollon/RNF41 myocardial messenger RNA diagnoses cardiac allograft apoptosis in rejection.

abstract：BACKGROUND:Posttransplant lymphoproliferative disease (PTLD) is a major complication after bone marrow and solid organ transplantation. The disease encompasses a spectrum of abnormal, Epstein-Barr virus (EBV)-associated B-cell proliferations. We have previously shown that EBV-infected, spontaneous lymphoblastoid cell l...

journal_title：Transplantation

authors： Nepomuceno RR,Snow AL,Robert Beatty P,Krams SM,Martinez OM

更新日期：2002-08-15 00:00:00

abstract：:We have studied organ allograft survival in rhesus monkeys conditioned with myeloablative total-body irradiation and T cell-depleted autologous bone marrow transplantation then given a heterotopic MHC-mismatched cardiac allograft in the immediate postmyeloablative period. This model has enabled us to investigate the r...

journal_title：Transplantation

authors： Moses RD,Sundeen JT,Orr KS,Roberts RR,Gress RE

更新日期：1989-11-01 00:00:00

abstract：:The effects of mismatching for DR antigens on renal allograft survival rates have largely been restricted to analyses of cadaver transplant results. Analyses of HLA matching in recipients of transplants from related donors have focused on the number of haplotypes shared between the recipients without regard to DR, or ...

journal_title：Transplantation

authors： Sutherland DE,Morrow CE,Kaufman D,Fryd DS,Najarian JS,Burke M,Noreen H,Segall M,Bach FH

更新日期：1983-12-01 00:00:00

abstract：BACKGROUND:The pig is currently considered to be the most likely candidate for a xenogenic-organ source. Anti-pig human T-cell response via co-stimulatory molecules has been studied with great interest. The soluble form of porcine CD80 has recently been cloned and characterized, but the sequence of the transmembrane fo...

journal_title：Transplantation

authors： Wada M,Amae S,Sasaki H,Ishii T,Sano N,Nio M,Hayashi Y,Ohi R

更新日期：2003-06-15 00:00:00

abstract：:Temperature is a key parameter in organ preservation that has been consistently linked to primary nonfunction (PNF). In this communication, and for the first time anywhere, continued and direct measurements of human liver intraparenchymal temperatures are reported in six clinical cases of orthotopic liver transplantat...

journal_title：Transplantation

authors： Villa R,Fondevila C,Erill I,Guimerà A,Bombuy E,Gómez-Suárez C,Sacristán JC,García-Valdecasas JC

更新日期：2006-02-15 00:00:00

abstract：BACKGROUND:The current shortage of organ donors has led many centers to use marginal and nonheart-beating donors (NHBDs). Recent research has implicated the infiltration of lymphocytes as an important mediator of ischemia-reperfusion injury (IRI). FTY720 is an immunosuppressant that promotes lymphocyte sequestration in...

journal_title：Transplantation

authors： Delbridge MS,Shrestha BM,Raftery AT,El Nahas AM,Haylor JL

更新日期：2007-07-27 00:00:00

abstract：:Rat, hamster, and rabbit islets were transplanted into diabetic C57BL/B6 mice. The effect on islet xenograft survival of low-temperature culture of the donor islets, alpha L3T4 treatment of the recipients for seven days, and transplantation of the grafts either in the renal capsule or in the liver via the portal vein ...

journal_title：Transplantation

authors： Lacy PE,Ricordi C,Finke EH

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND:The clinical symptoms, histological findings, and treatments for antibody-mediated rejection (AMR), which is the leading cause of graft loss in adult ABO-incompatible liver transplantation (ABO-I-LT), have rarely been discussed. METHODS:We performed adult living donor ABO-I-LT on six patients. We used anti-...

journal_title：Transplantation

authors： Morioka D,Togo S,Kumamoto T,Takeda K,Matsuo K,Inayama Y,Yamanaka S,Tanaka K,Endo I,Maegawa J,Shimada H

更新日期：2008-01-27 00:00:00

abstract：:Fine-needle aspiration biopsies were used for clinical monitoring of liver allografts; 21 patients with an inflammatory episode of acute rejection (12.0 +/- 3.3 CIU at the peak) were studied; all episodes were reversible. The inflammatory infiltrate consisted mainly of lymphoid cells, including lymphoid blasts, with i...

journal_title：Transplantation

authors： Lautenschlager I,Höckerstedt K,Salmela K,Isoniemi H,Holmberg C,Jalanko H,Häyry P

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND:The potential risk of transmission of porcine endogenous retroviruses (PERV) from xenogeneic donors into humans has been widely debated. Because we were involved in a phase I/II clinical trial using a bioartificial liver support system (BLSS), we proceeded to evaluate the biosafety of this device. MATERIALS...

journal_title：Transplantation

authors： Kuddus R,Patzer JF 2nd,Lopez R,Mazariegos GV,Meighen B,Kramer DJ,Rao AS

更新日期：2002-02-15 00:00:00

abstract：BACKGROUND:Brain death (BD) affects the viability of lungs for transplantation. A correlation exists between high lung inflammation after BD and the decrease in female sex hormones, especially estradiol. Therefore, we investigated the effects of 17β-estradiol (E2) treatment on the lungs of female brain dead rats. METH...

journal_title：Transplantation

authors： Ricardo-da-Silva FY,Armstrong R Jr,Vidal-Dos-Santos M,Correia CJ,Coutinho E Silva RDS,da Anunciação LF,Moreira LFP,Leuvenink HGD,Breithaupt-Faloppa AC

更新日期：2020-10-07 00:00:00

abstract：BACKGROUND:Renal allografts were performed in rhesus monkeys using FN18-CRM9, a potent immunotoxin capable of depleting T cells to less than 1% of baseline levels in blood and lymph nodes, as a preparative agent. We have recently reported that animals pretreated with FN18-CRM9 1 week before transplantation without furt...

journal_title：Transplantation

authors： Fechner JH Jr,Vargo DJ,Geissler EK,Graeb C,Wang J,Hanaway MJ,Watkins DI,Piekarczyk M,Neville DM Jr,Knechtle SJ

更新日期：1997-05-15 00:00:00

abstract：:Endothelial injury plays a central role in the pathophysiologic mechanisms underlying cardiac allograft vasculopathy (CAV). Although the accelerated course of CAV and its localization to the allograft support an important role for the alloimmune response, there is considerable evidence implicating lipoprotein abnormal...

journal_title：Transplantation

authors： Valantine HA

更新日期：2003-09-27 00:00:00

abstract：:Rapamycin prolongs allograft survival and induces donor-specific tolerance in some small animal transplant models. Large animal studies, however, are limited. We studied rapamycin in a porcine renal allograft model. Donor-recipient combinations were chosen based on high response in pretransplant MLCs. Allografts were ...

journal_title：Transplantation

authors： Almond PS,Moss A,Nakhleh RE,Melin M,Chen S,Salazar A,Shirabe K,Matas AJ

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND:To optimize the methods used for human islet isolation for transplantation, it is important to improve our understanding of the structure of the islet-exocrine interface. In this study, the composition of collagen subtypes in the interface have been characterized and quantified in human pancreas. METHODS:Hu...

journal_title：Transplantation

authors： Hughes SJ,Clark A,McShane P,Contractor HH,Gray DW,Johnson PR

更新日期：2006-02-15 00:00:00

abstract：BACKGROUND:There is a lack of information about survival after dropout from the liver transplant waiting list. Therefore, we aimed to assess the overall survival, and risk factors for death, after waiting list dropout due to hepatocellular carcinoma (HCC) progression. METHODS:We assessed patients who dropped out of th...

journal_title：Transplantation

authors： Gorgen A,Rosales R,Sadler E,Beecroft R,Knox J,Dawson LA,Ghanekar A,Grant D,Greig PD,Sapisochin G

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Mixed lymphohematopoietic chimerism can provide an effective means of inducing longterm immunological tolerance and has been documented in a monkey allograft model. A conditioning regimen including nonmyeloablative or myeloablative irradiation and splenectomy has been used to induce chimerism in a pig-to-pri...

journal_title：Transplantation

authors： Kozlowski T,Monroy R,Xu Y,Glaser R,Awwad M,Cooper DK,Sachs DH

更新日期：1998-07-27 00:00:00

abstract：:Plasma levels of main granulocyte components of patients after cadaveric renal transplantation were compared 9 days postoperative with the plasma levels of patients undergoing aortofemoral and iliacofemoral bypass operation or abdominal surgery. Lactoferrin values were significantly lower in patients under immunosuppr...

journal_title：Transplantation

authors： Hörl WH,Wanner C,Riegel W,Schlosser W,Wilms H,Schollmeyer P

更新日期：1989-01-01 00:00:00

abstract：:To formulate a model predicting survival after liver retransplantation, we analyzed in detail the last 150 cases of hepatic retransplantation at UCLA. Cox proportional hazards regression analysis identified five variables that demonstrated independent simultaneous prognostic value in estimating patient survival after ...

journal_title：Transplantation

authors： Markmann JF,Gornbein J,Markowitz JS,Levy MF,Klintmalm GB,Yersiz H,Morrisey M,Drazan K,Farmer DG,Ghobrial RM,Goss J,Seu P,Martin P,Goldstein LI,Busuttil RW

更新日期：1999-02-15 00:00:00

abstract：:Renal vasoconstriction has been implicated as a major contributing factor for the nephrotoxic effects of cyclosporine. In an attempt to assess the relative contribution of thromboxane (Tx), the effects of coadministering CsA with the selective Tx synthetase inhibitor, Dazmegrel (DAZ) (Pfizer, Inc.), were determined. R...

journal_title：Transplantation

authors： Gladue RP,Newborg MF

更新日期：1991-11-01 00:00:00

abstract：:The effect of the tritiated thymidine (3H-TdR) suicide technique on the ability of donor cells to induce fatal graft-versus-host disease (GVHD) was studied. C57BL/6 (H-2b) spleen cells were stimulated in vitro with irradiated BALB/c (H-2d) Moloney lymphoma cells in mixed culture and 3H-TdR of high-specific activity ad...

journal_title：Transplantation

authors： Cheever MA,Einstein AB Jr,Kempf RA,Fefer A

更新日期：1977-04-01 00:00:00

abstract：:It has been postulated that the establishment of acquired, neonatal immunologic tolerance is due to a "deficit" in interleukin 2 (IL-2). To test this hypothesis, chickens were made immunologically tolerant to both major and minor histocompatibility antigens by transplantation of skin grafts onto newly hatched recipien...

journal_title：Transplantation

authors： Tempelis CH,Hála K,Krömer G,Schauenstein K,Wick G

更新日期：1988-02-01 00:00:00

abstract：:Preformed recipient HLA-specific antibodies can cause hyperacute rejection of a transplanted kidney if they are directed against mismatched donor HLA antigens. To avoid hyperacute rejection it is essential that recipient antibodies be identified during patient workup for transplantation and HLA antigens to which a pat...

journal_title：Transplantation

authors： Martin S

更新日期：2001-05-27 00:00:00

abstract：BACKGROUND:Kidney transplantation (KT) of human immunodeficiency virus (HIV)-positive patients has transformed the management of end-stage kidney disease in this population. Although favourable outcomes have been reported, patients experience high rates of acute allograft rejection (AR). We examined factors associated ...

journal_title：Transplantation

authors： Gathogo E,Harber M,Bhagani S,Levy J,Jones R,Hilton R,Davies G,Post FA,UK HIV Kidney Transplantation Study Group.

更新日期：2016-04-01 00:00:00

abstract：:The protective effect of oxygen free radical scavenger superoxide dismutase (SOD) against the warm ischemic damage that occurs in kidneys harvested from non-heart-beating donors is controversial because of its short half-life. In this model, we compared the protective effect of SOD and two longer lasting polyethylene ...

journal_title：Transplantation

authors： Morpurgo E,Cadrobbi R,Morpurgo M,Rigotti P,Schiavon F,Schiavon O,Caliceti P,Ancona E,Veronese FM

更新日期：1996-11-15 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate familial amyloidotic polyneuropathy, Portuguese type patients' endocrine cell content in the stomach and duodenum before and after liver transplantation, and to relate the findings to the patients' gastrointestinal disturbances. METHODS:Ten liver-transplanted familia...

journal_title：Transplantation

authors： Anan I,El-Salhy M,Nyhlin N,Suhr OB

更新日期：2000-09-15 00:00:00

abstract：:The incidence of interstitial pneumonitis (IP) was reviewed in 70 consecutive patients who received autologous marrow transplants for hematologic malignancies. All patients were treated with total-body irradiation (TBI), with or without other chemotherapeutic agents. Seven patients (10%) developed IP, 3 were due to cy...

journal_title：Transplantation

authors： Pecego R,Hill R,Appelbaum FR,Amos D,Buckner CD,Fefer A,Thomas ED

更新日期：1986-11-01 00:00:00

abstract：:Spontaneous rupture of the liver has been described in association with many benign and malignant conditions. We report, to our knowledge, the first case of spontaneous rupture of the liver upon revascularization, requiring total hepatectomy and portocaval shunt, followed by successful retransplantation. Routine patho...

journal_title：Transplantation

authors： Mistry BM,Solomon H,Garvin PJ,Durham RM,Turnage S,Bacon BR,Galvin N,Varma CR

更新日期：2000-05-27 00:00:00

abstract：BACKGROUND:Arterial hypertension (HT) is common in renal transplant recipients (RTRs). Control of HT is not optimal in this high-risk population despite recommendations for target blood pressure levels under 130/80 mm Hg. METHODS:We performed a cross-sectional analysis of the prevalence of uncontrolled HT, and using a...

journal_title：Transplantation

authors： Vetromile F,Pernin V,Szwarc I,Garrigue V,Delmas S,Mourad G,Fesler P

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Prognostic models, which estimate survival probabilities, enable the survival benefit from a procedure to be assessed and allow the comparison of outcomes between centers. We therefore compared three models that estimate survival in the absence of transplantation for patients with alcoholic liver disease (AL...

journal_title：Transplantation

authors： Young TA,Neuberger J,Longworth L,Ratcliffe J,Buxton MJ,Cost-Effectiveness in Liver Transplantation Study Team.

更新日期：2003-11-27 00:00:00