Inhibitor against coagulation factor V after liver transplantation.

abstract：BACKGROUND:Increasing clinical evidence suggests that delayed initial function secondary to ischemia/reperfusion injury alone, and particularly in combination with early episodes of acute rejection, reduces kidney allograft survival over time. METHODS:We investigated changes developing over the long term following a s...

journal_title：Transplantation

authors： Takada M,Nadeau KC,Shaw GD,Tilney NL

更新日期：1997-12-15 00:00:00

abstract：BACKGROUND:Significant disparity exists in the United Kingdom between the need for organ transplant and supply of deceased donor organs. In the recent years, efforts to increase donation has improved the rate of mainly deceased donors after circulatory death and from older donors. The rate of donation from pediatric po...

journal_title：Transplantation

authors： Dave RV,Hakeem AR,Dawrant MJ,Ecuyer CL,Lewington AJ,Attia MS,Hostert L,Finlay E,Ahmad N

更新日期：2015-09-01 00:00:00

abstract：:In the present study the functional and morphologic effects of two pulmoplegic solutions are evaluated. Single left-lung allotransplantation with ligation of the right pulmonary artery was performed in 15 piglets (13-20 kg). The lungs were preserved after donor prostaglandin E-1 treatment with single pulmonary artery ...

journal_title：Transplantation

authors： Lehtola A,Harjula A,Heikkilä L,Hämmäinen P,Taskinen E,Kurki T,Salmenperä M,Mattila S

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:BK virus-associated nephropathy (BKVN) is associated with an increased risk of graft failure. METHODS:Levels of mRNAs encoding proteins implicated in inflammation and fibrosis were measured in urine collected at the time of biopsy diagnosis of BKVN in 29 kidney graft recipients and analyzed for prognosticat...

journal_title：Transplantation

authors： Dadhania D,Snopkowski C,Muthukumar T,Lee J,Ding R,Sharma VK,Christos P,Bang H,Kapur S,Seshan SV,Suthanthiran M

更新日期：2013-07-27 00:00:00

abstract：BACKGROUND:Increased use of pediatric deceased donor kidneys could enlarge the deceased donor kidney pool. Kidney transplant outcomes from small pediatric donors were compared with those from ideal kidney (IK) and expanded criteria kidney (ECK) donors to understand the optimal use of pediatric donor kidneys. METHODS:K...

journal_title：Transplantation

authors： Suneja M,Kuppachi S,Katz D,Hunsicker L

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:The impact of recipient body mass index on graft and patient survival after pancreas transplantation is not well known. METHODS:We have analyzed data from all pancreas transplant recipients reported in the Scientific Registry of Transplant Recipients between 1987 and 2011. Recipients were categorized into B...

journal_title：Transplantation

authors： Bédat B,Niclauss N,Jannot AS,Andres A,Toso C,Morel P,Berney T

更新日期：2015-01-01 00:00:00

abstract：:Diarrhea is a frequent but overlooked complication of kidney transplantation. Diarrhea is repeatedly neglected, often considered by patients and clinicians an unavoidable side effect of immunosuppressive regimens. It is, however, associated with a significant impairment in life quality. Severe and chronic posttranspla...

journal_title：Transplantation

authors： Aulagnon F,Scemla A,DeWolf S,Legendre C,Zuber J

更新日期：2014-10-27 00:00:00

abstract：BACKGROUND:Chronic cyclosporine (CsA) nephropathy, which has been unequivocally documented in recipients of heart, heart-lung, liver, or bone marrow transplants, as well as in nontransplant situations, usually results in a progressive deterioration of renal function. In this study, we assessed the potential reversibili...

journal_title：Transplantation

authors： Mourad G,Vela C,Ribstein J,Mimran A

更新日期：1998-03-15 00:00:00

abstract：:Patients with renal transplants that survive the first year often ask about the chance of long-term function. We studied 1850 patients with primary transplants from June 7, 1963 to September 1, 1988 who had graft survival of greater than 1 year. Patients were grouped by donor type, diabetic status, and whether or not ...

journal_title：Transplantation

authors： Fischel RJ,Payne WD,Gillingham KJ,Dunn DL,Sutherland DE,Matas AJ,Najarian JS

更新日期：1991-01-01 00:00:00

abstract：:We have previously demonstrated that streptozotocin-induced diabetic rats have decreased guanylate cyclase (EC 4.6.1.2) activity in liver and other tissues which was returned to normal by the administration of exogenous insulin. Since successful pancreatic islet transplants have been shown to lower basal hepatic gluco...

journal_title：Transplantation

authors： Vesely DL,Selawry H,Levey GS

更新日期：1979-06-01 00:00:00

abstract：BACKGROUND:Remote ischemic preconditioning (RIPC) protects against liver ischemia reperfusion (IR) injury. An essential circulating mediator of this protection is nitric oxide (NO) induced by lower limb RIPC. One of the mechanisms through which NO generally acts is the soluble guanylyl cyclase-cyclic GMP (sGC-cGMP) pat...

journal_title：Transplantation

authors： Abu-Amara M,Yang SY,Quaglia A,Rowley P,Tapuria N,Fuller B,Davidson B,Seifalian A

更新日期：2012-05-15 00:00:00

abstract：:Crigler-Najjar type 1 disease (CNS1) is the result of a genetic defect, leading to complete functional loss of an enzyme which glucuronidates bilirubin. As a consequence, unconjugated bilirubin accumulates and may cause kernicterus, the most serious complication in adolescents. Phototherapy effectively adjusts bilirub...

journal_title：Transplantation

authors： Schauer R,Lang T,Zimmermann A,Stangl M,Da Silva L,Schildberg FW,Rau HG

更新日期：2002-01-15 00:00:00

abstract：:To determine the extent to which pretransplant immunity resulting from natural infection protects against cytomegalovirus (CMV) disease, we analyzed CMV serology on 153 kidney donor and recipient pairs and followed transplant patients to determine incidence and severity of CMV disease. The overall incidence of CMV dis...

journal_title：Transplantation

authors： Smiley ML,Wlodaver CG,Grossman RA,Barker CF,Perloff LJ,Tustin NB,Starr SE,Plotkin SA,Friedman HM

更新日期：1985-08-01 00:00:00

abstract：:Forty-three human liver allograft biopsies and normal liver were directly analyzed for inflammatory and immunoregulatory cytokine gene expression by polymerase chain reaction (PCR). IL-5 gene expression was predominantly present in biopsies from liver allografts with histopathological evidence of acute rejection. IL-2...

journal_title：Transplantation

authors： Martinez OM,Krams SM,Sterneck M,Villanueva JC,Falco DA,Ferrell LD,Lake J,Roberts JP,Ascher NL

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:Vitamin D deficiency has been reported in different chronic pulmonary diseases like asthma and chronic obstructive pulmonary disease, but little is known in lung transplant recipients. METHODS:Serum 25-hydroxyvitamin D (25-OHD) levels and pulmonary function (forced expiratory volume in 1 sec [FEV(1)] %predi...

journal_title：Transplantation

authors： Verleden SE,Vos R,Geenens R,Ruttens D,Vaneylen A,Dupont LJ,Verleden GM,van Raemdonck DE,Vanaudenaerde BM

更新日期：2012-01-27 00:00:00

abstract：:We report two cases of Kaposi's sarcoma (KS) after orthotopic liver transplantation for cirrhosis of the liver related to hepatitis C virus. Both cases were Saudi-born Arabs who were negative for human immunodeficiency virus; one patient was receiving FK506 plus prednisolone, and the other patient was receiving FK506....

journal_title：Transplantation

authors： Rezeig MA,Fashir BM,Hainau B,Al Ashgar HI

更新日期：1997-05-27 00:00:00

abstract：:We describe a patient transfused with 200 ml of donor fresh whole blood three times at 2-week intervals. Three weeks after the last transfusion, transplantation and splenectomy were done at the same time. Splenic cells from this DST pretreated patient were fused with murine myeloma cells (X63-Ag8, 653). With DST pretr...

journal_title：Transplantation

authors： Kawamura T,Sakagami K,Haisa M,Morisaki F,Takasu S,Inagaki M,Oiwa T,Orita K

更新日期：1989-09-01 00:00:00

abstract：:Acute graft-versus-host-disease is classically described as reactivity of donor lymphocytes to recipient alloantigens. To date there is debate as to whether GVHD can be induced across a species barrier. We recently reported the induction of stable xenogeneic chimerism (rat-->mouse) and donor-specific transplantation t...

journal_title：Transplantation

authors： Cooper MH,Nalesnik MA,Watkins SC,Hoffman RA,Ildstad ST

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND:In patients with cytomegalovirus (CMV) disease, regular monitoring of viral loads and treatment until negative are recommended. However, with more sensitive polymerase chain reaction (PCR) assays and cellular peripheral sample types, detection of low-level viremia is achievable. We compared a whole blood rea...

journal_title：Transplantation

authors： Lisboa LF,Asberg A,Kumar D,Pang X,Hartmann A,Preiksaitis JK,Pescovitz MD,Rollag H,Jardine AG,Humar A

更新日期：2011-01-27 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate the population pharmacokinetics of tacrolimus in pediatric liver transplant recipients and to identify factors that may explain pharmacokinetic variability. METHODS:Data were collected retrospectively from 35 children who received oral immunosuppressant therapy with ...

journal_title：Transplantation

authors： Staatz CE,Taylor PJ,Lynch SV,Willis C,Charles BG,Tett SE

更新日期：2001-09-27 00:00:00

abstract：:The influence of methotrexate on the development of immunity to the line 10 hepatoma was studied in guinea pigs. Chronic methotrexate treatment had no apparent effect on the ability of immune guinea pigs to suppress the growth of inoculated tumor cells. In contrast, the same methotrexate regimen inhibited the developm...

journal_title：Transplantation

authors： Shu S,Fonseca LS,Hunter JT,Rapp HJ

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:Long-term results of prospective randomized trials comparing triple immunosuppressive strategies combining tacrolimus (TAC) or cyclosporine A (CsA) with mycophenolate mofetil (MMF) and steroids after heart transplantation (HTX) are rarely published. Therefore, we collected long-term follow-up data of an inte...

journal_title：Transplantation

authors： Guethoff S,Meiser BM,Groetzner J,Eifert S,Grinninger C,Ueberfuhr P,Reichart B,Hagl C,Kaczmarek I

更新日期：2013-02-27 00:00:00

abstract：:We examined graft and patient survival rates of 47,146 patients in the United Network for Organ Sharing registry following transplants between donors and recipients who were cytomegalovirus (CMV) antibody negative and positive. CMV positivity increased with age to about 80% in patients over 60. Seropositivity was seen...

journal_title：Transplantation

authors： Hirata M,Terasaki PI,Cho YW

更新日期：1996-07-15 00:00:00

abstract：BACKGROUND:Extracorporeal membrane oxygenation (ECMO) can be used to maintain oxygen delivery and provide hemodynamic support in case of circulatory and/or respiratory failure. Although the role of ECMO has emerged in the setting of adult liver transplantation (LT), data in children are limited. We aimed to describe th...

journal_title：Transplantation

authors： Ziogas IA,Johnson WR,Matsuoka LK,Rauf MA,Thurm C,Hall M,Bacchetta M,Godown J,Alexopoulos SP

更新日期：2020-08-13 00:00:00

abstract：:The effects of dietary (10% calories) safflower (SAF), evening primrose (EPO), and fish oil (F) as sources of linoleic acid (control), gamma-linolenic acid, and long-chain n-3 fatty acids, respectively, on cardiovascular and renal responses to chronic (5 weeks) cyclosporine administration were studied in male borderli...

journal_title：Transplantation

authors： Mills DE,Ward RP,McCutcheon D,Dixon H,Ly H,Scholey J

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND:In an effort to define reliable assays that might predict postimmunosuppressant-withdrawal development of chronic rejection (CR), despite conditioning for tolerance induction, we evaluated various immunological responses in nonhuman primate renal allograft recipients. METHODS:Fourteen Cynomolgus monkeys rec...

journal_title：Transplantation

authors： Boskovic S,Kawai T,Smith RN,Wee SL,Nadazdin O,Koyama I,Saidman S,Cardarelli F,Elias N,Sykes M,Strom T,Colvin RB,Sachs DH,Cosimi AB

更新日期：2006-09-27 00:00:00

abstract：BACKGROUND:Metabolic syndrome (MS) is a known cardiovascular risk factor in the general population. We explored the influence of MS on the occurrence of atherosclerotic events (AEs) after renal transplantation. METHODS:Three hundred thirty-seven renal transplant recipients were included in the study. Various parameter...

journal_title：Transplantation

authors： Courivaud C,Kazory A,Simula-Faivre D,Chalopin JM,Ducloux D

更新日期：2007-06-27 00:00:00

abstract：OBJECTIVES:En bloc pediatric kidney transplants (EBPKT) are still a subject of controversy. The aim of this study was to determine whether acceptable long-term graft survival and function can be achieved in EBPKT compared with the transplant of single, cadaveric, adult donor kidneys. METHODS:A retrospective review was...

journal_title：Transplantation

authors： Sánchez-Fructuoso AI,Prats D,Pérez-Contín MJ,Marques M,Torrente J,Conesa J,Grimalt J,Del Rio F,Núñez JR,Barrientos A

更新日期：2003-10-27 00:00:00

abstract：BACKGROUND:We previously reported that no cytotoxic T-lymphocyte precursor frequencies (CTLpf) were found in 60% of patients on azathioprine or mycophenolate mofetil+Pred long after kidney transplantation. We questioned whether the absence of donor-specific CTLpf was associated with low levels of stimulatory Th1 (tumor...

journal_title：Transplantation

authors： van Besouw NM,de Kuiper R,van der Mast BJ,van de Wetering J,Baan CC,Weimar W

更新日期：2009-05-27 00:00:00

abstract：BACKGROUND:In recent years, transplantation of islets and pancreas has become a viable option for patients debilitated with type I diabetes. The success of islet transplantation has been attributed to the ability to isolate high quality islets for transplantation and capacity to maintain the recipient's immunosuppressi...

journal_title：Transplantation

authors： Mohanakumar T,Narayanan K,Desai N,Ramachandran S,Shenoy S,Jendrisak M,Susskind BM,Olack B,Benshoff N,Phelan DL,Brennan DC,Fernandez LA,Odorico JS,Polonsky KS

更新日期：2006-07-27 00:00:00