Effect of timing of administration and quantity of blood transfusion on cadaver renal transplant survival.

abstract：:Ultraviolet (UV)-irradiated mice were compared with unirradiated mice for their susceptibility to primary and transplanted tumors etiologically unrelated to UV radiation. Although UV-irradiated mice are unable to reject transplants of highly antigenic syngeneic tumors induced by UV light, the growth of syngeneic, non-...

journal_title：Transplantation

authors： Kripke ML,Thorn RM,Lill PH,Civin CI,Pazmiño NH,Fisher MS

更新日期：1979-09-01 00:00:00

abstract：BACKGROUND:The administration of systemic immunosuppressive agents to recipients of solid organ or bone marrow transplants results in an immunocompromised status. As the number of organ recipients and their life span increase with recent progress in organ transplantation, ocular complications tend to become more divers...

journal_title：Transplantation

authors： Chung H,Kim KH,Kim JG,Lee SY,Yoon YH

更新日期：2007-03-27 00:00:00

abstract：:Immunosuppressive therapy increases the risk of recurrence of initial cancers in organ transplant patients, and compelling therapeutic protocols are needed to suppress the malignancy and protect the allograft. We examined the potential use of 15-deoxyspergualin (DSG) in relation to organ transplantation and cancer. Th...

journal_title：Transplantation

authors： Ohsawa I,Uemoto S,Kobayashi E,Murakami T

更新日期：2007-08-15 00:00:00

abstract：:Recent suggestions that the rat prostate is an alymphatic, immunologically privileged site stimulated further investigation of its status using a variety of techniques. Fixation of certain organs by vascular perfusion of glutaraldehyde followed by plastic embedding avoids the distortion and stromal reorganization that...

journal_title：Transplantation

authors： Neaves WB,Billingham RE

更新日期：1979-02-01 00:00:00

abstract：:There is considerable current interest in the possibility that long-term graft acceptance in clinical solid-organ transplantation might be dependent upon the development of a microchimeric state between the donor and recipient. This possibility has been prompted by the observation that in some transplant patients cell...

journal_title：Transplantation

authors： Bushell A,Pearson TC,Morris PJ,Wood KJ

更新日期：1995-05-27 00:00:00

abstract：:In a three-year period between January 1980 and December 1982, 242 consecutive cadaver transplant recipients in one center were tested before transplantation by cytotoxicity against a random panel of T and B lymphocytes at 5 degrees C and 37 degrees C incubation. They were also tested for HLA-A, B, and DR antigens. Ki...

journal_title：Transplantation

authors： Mendez R,Chatterjee SN,Mendez R,Bogaard T

更新日期：1985-09-01 00:00:00

abstract：:Seasonal variation in blood pressure (BP) has been described in the general and dialysis populations, with higher recordings noted in the winter than in the summer. This difference has been attributed to changes in weight, ambient temperature, and length of daylight. In this study, we sought to determine whether such ...

journal_title：Transplantation

authors： Prasad GV,Nash MM,Zaltzman JS

更新日期：2001-12-15 00:00:00

abstract：BACKGROUND:The once-daily (QD), prolonged-release formulation of tacrolimus has been shown to improve adherence versus twice-daily (BD) tacrolimus. Treatment nonadherence in transplant recipients has been associated with poor graft outcomes. METHODS:This open-label, parallel-group study randomized adults with end-stag...

journal_title：Transplantation

authors： Albano L,Banas B,Klempnauer JL,Glyda M,Viklicky O,Kamar N,Optimising immunoSuppression After Kidney transplantation with ADVAGRAF Study Group.

更新日期：2013-11-27 00:00:00

abstract：BACKGROUND:Success of human pancreatic islet isolation depends largely on the techniques used during pancreas procurement and the quality of the gland. Warm ischemia of the pancreas of any duration during organ procurement may be detrimental to subsequent islet yield and functional viability of the islets. The aim of t...

journal_title：Transplantation

authors： Lakey JR,Kneteman NM,Rajotte RV,Wu DC,Bigam D,Shapiro AM

更新日期：2002-04-15 00:00:00

abstract：BACKGROUND:Hepatic artery thrombosis (HAT) is a significant cause of morbidity after liver transplantation. The aims of this study are to identify and compare risk factors that might contribute to HAT. METHODS:A total of 424 liver transplants performed at the University of Virginia were reviewed. HAT was defined as co...

journal_title：Transplantation

authors： Oh CK,Pelletier SJ,Sawyer RG,Dacus AR,McCullough CS,Pruett TL,Sanfey HA

更新日期：2001-03-27 00:00:00

abstract：BACKGROUND:NKp46 expression in natural killer (NK) cells has recently been shown to affect the responsiveness to antiviral treatment in hepatitis C virus (HCV)-infected patients. However, the density of NKp46 on intrahepatic NK cells is remarkably higher than that on peripherally circulating NK cells, whereas the bioph...

journal_title：Transplantation

authors： Tanimine N,Tanaka Y,Abe T,Piao J,Chayama K,Ohdan H

更新日期：2016-02-01 00:00:00

abstract：:FK506 (tacrolimus) is a strong immunosuppressant: it has been approved as a drug for liver transplantation in Japan, the United States, and the United Kingdom. One of its main adverse effects is hyperglycemia. Thus, in this study, we investigated the mechanism and the reversibility of the hyperglycemia caused by FK506...

journal_title：Transplantation

authors： Tamura K,Fujimura T,Tsutsumi T,Nakamura K,Ogawa T,Atumaru C,Hirano Y,Ohara K,Ohtsuka K,Shimomura K

更新日期：1995-06-15 00:00:00

abstract：BACKGROUND:Human CD58 is an adhesion molecule that interacts with CD2 on lymphocytes. We describe here an antibody that blocks responses of human peripheral blood mononuclear cells (PBMCs) to porcine cells and reacts with a porcine protein with homology to CD58. METHODS:Antibodies were isolated with a screen for inhib...

journal_title：Transplantation

authors： Crosby K,Yatko C,Dersimonian H,Pan L,Edge AS

更新日期：2004-04-27 00:00:00

abstract：:Transplantation provides life-saving therapy to critically ill patients with end-stage organ failure. We found that the specialized knowledge of mental health clinicians and physicians, committed to the evaluation and management of transplant recipients, is essential for the optimal care of these patients who require ...

journal_title：Transplantation

authors： Surman OS,Cosimi AB,DiMartini A

更新日期：2009-06-27 00:00:00

abstract：BACKGROUND:In the hamster to rat xenogeneic combination, antibodies, T cells, and natural killer (NK) cells have all been implicated in the process of rejection. 3.2.3 is a mouse IgG1kappa monoclonal antibody (mAb) directed against NKR-P1A on rat NK cells. The purpose of this study was to evaluate the effect of this mA...

journal_title：Transplantation

authors： Gourlay WA,Chambers WH,Monaco AP,Maki T

更新日期：1998-03-15 00:00:00

abstract：:We examined the cytokine profiles associated with tolerance and rejection using the mouse model of neonatal tolerance. BALB/c mice primed with CAF1 splenocytes during the neonatal stage showed increased A/J skin graft survival of > 60 days and failed to develop anti-A/J cytotoxic responses, but rejected third-party C5...

journal_title：Transplantation

authors： Chen N,Field EH

更新日期：1995-04-15 00:00:00

abstract：BACKGROUND:The authors have investigated the effectiveness of virus detection from bronchoalveolar lavage (BAL) samples for the identification of symptomatic cytomegalovirus (CMV) infection in lung transplant recipients. METHODS:Thus, 275 BAL samples taken from 105 lung transplant recipients during follow-up were anal...

journal_title：Transplantation

authors： Zedtwitz-Liebenstein K,Jaksch P,Bauer C,Popow T,Klepetko W,Hofmann H,Puchhammer-Stöckl E

更新日期：2004-06-27 00:00:00

abstract：:Sixty-two adults who underwent orthotopic liver transplantations between February 1981 and June 1983 were followed for a mean of 170 days after the operation. Twenty-six patients developed 30 episodes of significant fungal infection. Candida species and Torulopsis glabrata were responsible for 22 episodes and Aspergil...

journal_title：Transplantation

authors： Wajszczuk CP,Dummer JS,Ho M,Van Thiel DH,Starzl TE,Iwatsuki S,Shaw B Jr

更新日期：1985-10-01 00:00:00

abstract：BACKGROUND:Successful pancreatic islet transplantation (PIT) has resulted in several transplant centers wanting to start PIT programs. PIT remains experimental and must be performed safely for its continued use. We describe the radiographic techniques used at our center and their results. METHODS:Between January 17, 2...

journal_title：Transplantation

authors： Goss JA,Soltes G,Goodpastor SE,Barth M,Lam R,Brunicardi FC,Froud T,Alejandro R,Ricordi C

更新日期：2003-07-15 00:00:00

abstract：BACKGROUND:Intestinal allograft mucosa undergoes repopulation with host immunocytes. However, critical changes within key immunocyte subsets are not known. METHODS:To explain acute cellular rejection after intestine transplantation (ITx) on the basis of altered mucosal immunocytes, rejecting and rejection-free ITx all...

journal_title：Transplantation

authors： Ningappa M,Ashokkumar C,Ranganathan S,Schmitt L,Higgs BW,Sun Q,Branca M,Mazariegos G,Zeevi A,Abu-Elmagd K,Squires R,Rudolph J,Alissa F,Hakonarson H,Sindhi R

更新日期：2012-12-27 00:00:00

abstract：BACKGROUND:Perioperative renal dysfunction in liver transplant recipients complicates maintenance immunosuppressive therapy, particularly in patients with hepatitis C. Calcineurin inhibitors exacerbate renal dysfunction and mammalian target-of-rapamycin inhibitors are generally avoided because of perceived perioperativ...

journal_title：Transplantation

authors： LaMattina JC,Jason MP,Hanish SI,Ottmann SE,Klassen DK,Potosky D,Hutson WR,Barth RN

更新日期：2014-01-27 00:00:00

abstract：:Predictors of survival after lung transplant were analyzed in a large cohort of 990 lung transplanted patients from a single center. The overall survival was 41.6%, (41.5% in males, and 41.8% in females), the average length of the follow up was 45.84+/-51.98 months (range 0-282.47 months). Females tend to live longer ...

journal_title：Transplantation

authors： Creel M,Studer SM,Schwerha J,Harper J,Ortiz L,Ragin C,Taioli E

更新日期：2008-04-27 00:00:00

abstract：:Cyclosporine (CsA) administration and nitric oxide (NO) blockade promote similar chronic renal hemodynamic alterations in rats. We evaluated various clinical CsA doses under conditions of NO blockade using L-NAME (N-nitro L-arginine methyl ester). Groups of Sprague-Dawley rats kept on a normal salt (+NaCl) or low-salt...

journal_title：Transplantation

authors： Gardner MP,Houghton DC,Andoh TF,Lindsley J,Bennett WM

更新日期：1996-05-27 00:00:00

abstract：BACKGROUND:Proteinuria is associated with endothelial dysfunction (ED) and increased mortality. We investigated whether urinary protein excretion (UPE) is correlated with markers of ED and whether these markers affect the association of proteinuria with mortality in renal transplant recipients (RTR). METHODS:Six hundr...

journal_title：Transplantation

authors： van Ree RM,Oterdoom LH,de Vries AP,Homan van der Heide JJ,van Son WJ,Navis G,Gans RO,Bakker SJ

更新日期：2008-12-27 00:00:00

abstract：BACKGROUND:Metrics for evaluating low-quality kidneys have failed to predict outcomes or reduce the kidney refusal and discard rates. Kidneys from extended-criteria donors (ECDs) and kidneys with ≥85% kidney donor profile indexes (KDPIs) might have different sensitivities to the proinflammatory milieu generated by brai...

journal_title：Transplantation

authors： Florim GMS,Caldas HC,Gonçalves NN,Bueno GOBE,Baptista MASF,Fernandes-Charpiot IMM,Abbud-Filho M

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:The incidence of stroke and risk factors for different subtypes of cerebrovascular (CBV) events in renal transplant recipients have not been examined in any large prospective controlled trial. METHODS:The Assessment of Lescol in Renal Transplantation was a randomized, double-blind, placebo-controlled study ...

journal_title：Transplantation

authors： Abedini S,Holme I,Fellström B,Jardine A,Cole E,Maes B,Holdaas H,ALERT Study Group.

更新日期：2009-01-15 00:00:00

abstract：:Mucosal injury is an immediate event following revascularization of small intestinal grafts in the context of transplantation (SBTx). The generation of oxygen free radicals (OFR) and tissue infiltration by activated neutrophils are consequences of ischemia and reperfusion and known causative factors of tissue injury; ...

journal_title：Transplantation

authors： Cicalese L,Caraceni P,Nalesnik MA,Borle AB,Schraut WH

更新日期：1996-07-27 00:00:00

abstract：BACKGROUND:LCP-Tacro is an extended-release formulation of tacrolimus designed for once-daily dosing. Phase 1 studies demonstrated greater bioavailability to twice-daily tacrolimus capsules and no new safety concerns. METHODS:In this phase 2 study, adult stable kidney transplant patients on tacrolimus capsules (Progra...

journal_title：Transplantation

authors： Gaber AO,Alloway RR,Bodziak K,Kaplan B,Bunnapradist S

更新日期：2013-07-27 00:00:00

abstract：BACKGROUND:The infiltration of epithelium by CD8+ T lymphocytes in human renal or liver allografts is a critical feature of acute rejection. CD103 expression can be acquired in vitro by CD8+ cytotoxic T lymphocytes in response to allogeneic renal epithelial cells and promotes their adhesion to epithelium and subsequent...

journal_title：Transplantation

authors： Leteurtre E,Copin MC,Labalette M,Noel C,Roumilhac D,Pruvot FR,Lecomte-Houcke M,Gosselin B,Dessaint JP

更新日期：2000-07-15 00:00:00

abstract：:Cyclosporine CsA nephrotoxicity was examined in male Sprague-Dawley rats with or without prior uninephrectomy, injected daily with 12.5 mg/kg CsA, and fed a salt-depleted or normal diet for 3-10 weeks. Control rats received the CsA vehicle. CsA induced a fall in creatinine clearance in salt-depleted rats, from 1.3 +/-...

journal_title：Transplantation

authors： Rosen S,Greenfeld Z,Brezis M

更新日期：1990-02-01 00:00:00