Abstract：
:We have examined the molecular basis of the response of individuals of D. melanogaster to artificial selection for high and low abdominal bristles. By monitoring the fate of particular rDNA spacer length variants associated with individually isolated X and Y chromosomes, we show that flies from the low bristle number selection lines have undergone an unequal exchange between the X and Y rDNA arrays. Such exchanges result in translocations between X and Y chromosomes, visualised as X.Y compound chromosomes at mitosis. Transfer of few copies of a length variant between X and Y indicates a clustering of variants. Flies that have reverted back to wild-type seemingly have undergone a second unequal exchange, giving rise to a compound X.Y chromosome containing Y rDNA of normal amounts. Unequal exchanges between X and Y rDNA arrays could contribute to the observed coevolution of rDNA sequences on these chromosomes. The biological significance of this outcome is discussed.
journal_name
Celljournal_title
Cellauthors
Coen ES,Dover GAdoi
10.1016/0092-8674(83)90027-2subject
Has Abstractpub_date
1983-07-01 00:00:00pages
849-55issue
3eissn
0092-8674issn
1097-4172pii
0092-8674(83)90027-2journal_volume
33pub_type
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