Phospholipid liposomes and prolactin secretion: effects on spontaneous and drug-induced hyperprolactinaemia.

abstract：:A number of experimental studies report that biological systems can be affected by in vivo exposure to low frequency and extremely low frequency electromagnetic fields. However, attempts to independently replicate some of these studies have shown the reported effects to be elusive. The difficulty in replicating result...

journal_title：Life sciences

authors： Ubeda A,Díaz-Enriquez M,Martínez-Pascual MA,Parreño A

更新日期：1997-01-01 00:00:00

abstract：:The biosynthesis of phospholipids during differentiation of normal and dystrophic muscle cells was studied using [32Pi] added to primary culture media. Labeled phosphatides were separated by two-dimensional thin-layer chromatography, exposing the plates to HCl vapors between solvents to cleave the alk-1-enyl bonds. Ph...

journal_title：Life sciences

authors： Leskawa KC,Erwin RE,Hogan EL

更新日期：1986-01-13 00:00:00

abstract：:The effects of caffeine (Cf), theophylline (Tph) and theobromine (Tb) on the adrenal cortex were studied. No direct effect (hypophysectomized: hypo(-) rats) was observed with any of the three methyl-xanthines (MX) after chronic oral administration (5 days). An indirect effect (via the hypothalamo-hypophyseal-adrenal a...

journal_title：Life sciences

authors： Okyayuz GI,Ventura MA,Gardey C,Rey E,Thiroux G

更新日期：1985-09-30 00:00:00

abstract：:The role of the autonomic nervous system in the modulation of the immune response to emotional stimuli, was established in rats subjected to the passive avoidance test. An increase in splenic primary antibody response directed against SRBC was found after exposure of rats to the passive avoidance apparatus (novelty). ...

journal_title：Life sciences

authors： Croiset G,Heijnen CJ,van der Wal WE,de Boer SF,de Wied D

更新日期：1990-01-01 00:00:00

abstract：:The purpose of this study was to characterize behavioral interactions between glutamatergic and serotonergic 5-HT2 receptors. Both competitive (AP-5 [D-2-amino-5-phosphovalerate] and D-CPP [3-(2carboxypiperazine-4yl)-propylphosphonate]) and noncompetitive (MK-801 [dizocilpine], ketamine, dextrorphan and dextromethorph...

journal_title：Life sciences

authors： Kim HS,Park IS,Park WK

更新日期：1998-01-01 00:00:00

abstract：:A number of studies have been made on the role played by endogenous opioid peptides in the secretion of LH in humans. However no previous studies have compared the effects of the most potent pharmacological agonist and antagonist, morphine and naloxone, in the same subjects. The present study examined the acute effect...

journal_title：Life sciences

authors： Petraglia F,Porro C,Facchinetti F,Cicoli C,Bertellini E,Volpe A,Barbieri GC,Genazzani AR

更新日期：1986-06-09 00:00:00

abstract：:Immunoreactive (ir) beta-endorphin (b-END) and dynorphin (DYN) in rat brain and pituitary were measured after food and water deprivation and from brains taken during either day or night. In other rats, eating and drinking were measured following lesions in the arcuate n. Ir-DYN levels are higher in hypothalamus and lo...

journal_title：Life sciences

authors： Reid LD,Konecka AM,Przewłocki R,Millan MH,Millan MJ,Herz A

更新日期：1982-10-18 00:00:00

abstract：:Indomethacin (0.14-.5 mM concentration) inhibits nitric oxide production in murine peritoneal macrophages. This was evidenced by measuring both nitrite production or 14C-L-citrulline formation. The inhibition was caused by the diminution of de novo inducible nitric oxide synthase production as demonstrated by Western ...

journal_title：Life sciences

authors： Hrabák A,Vercruysse V,Kahán IL,Vray B

更新日期：2001-03-09 00:00:00

abstract：:Peripheral blood cells express the complete non-neuronal cholinergic system. For example synthesis of acetylcholine and nicotinic as well muscarinic receptors have been demonstrated in leucocytes isolated from human peripheral blood. In the present experiments mononuclear cells and granulocytes were isolated from the ...

journal_title：Life sciences

authors： Neumann S,Razen M,Habermehl P,Meyer CU,Zepp F,Kirkpatrick CJ,Wessler I

更新日期：2007-05-30 00:00:00

abstract：AIMS:Amiodarone (AMIO) is currently used in medical practice to reverse ventricular tachycardia. Here we determine the effects of AMIO in the electromechanical properties of isolated left ventricle myocyte (LVM) from mice and guinea pig and in a cellular model of Long QT Syndrome Type 3 (LQTS-3) using anemone neurotoxi...

journal_title：Life sciences

authors： Beserra SS,Santos-Miranda A,Sarmento JO,Miranda VM,Roman-Campos D

更新日期：2020-08-15 00:00:00

abstract：:Endogenous dopamine (DA) and norepinephrine (NE) in the superfusate from slices of rat medial prefrontal cortex were measured by high-performance liquid chromatography coupled to electrochemical detection (HPLC-ECD). Stimulation with high K+ or methamphetamine (MAP) evoked a dose-dependent elevation in the release of ...

journal_title：Life sciences

authors： Ohmori T,Koyama T,Yamashita I

更新日期：1991-01-01 00:00:00

abstract：:The aim of this study was to investigate whether the A1/A2 receptor agonist, 5'-N-ethylcarboxamidoadenosine (NECA), and the selective A1 agonist, N6-cyclopentyladenosine (CPA), induced physical dependence by quantifying specific antagonist-precipitated withdrawal syndromes in conscious rats. In addition, the presence ...

journal_title：Life sciences

authors： Coupar IM,Tran BL

更新日期：2001-07-06 00:00:00

abstract：:The cytokeratins from human bladder and esophageal epithelia were separated using chromatographic techniques. The cytokeratins were first extracted from fresh autopsy tissue using high and low salt buffers. Urea, 8.0-9.5 M, was used to solubilize the resulting cytokeratin pellet. Imidazole was found to increase the so...

journal_title：Life sciences

authors： Meiklejohn B,Nagle RB,McDaniel KM,Wilson GS

更新日期：1990-01-01 00:00:00

abstract：:In this study, we investigated the effects of zinc L-carnosine, an anti-ulcer drug, on acetic acid-induced colonic mucosal injury and the correlation of these effects with expression of 72-kDa heat shock proteins (HSP72) and nuclear factor kappa B (NF-kappaB) activation in rat colonic mucosa in vivo. After intrarectal...

journal_title：Life sciences

authors： Odashima M,Otaka M,Jin M,Wada I,Horikawa Y,Matsuhashi T,Ohba R,Hatakeyama N,Oyake J,Watanabe S

更新日期：2006-11-10 00:00:00

abstract：:It has been shown that the antagonism of glutamate receptors activity was able inhibit proliferation and induce apoptosis in several neuronal and non-neuronal cancer cell lines. In addition, it has been shown that glutamate might facilitate the spread and growth of leukemia T cells through interactions with AMPA recep...

journal_title：Life sciences

authors： Parenti S,Casagrande G,Montanari M,Espahbodinia M,Ettari R,Grande A,Corsi L

更新日期：2016-05-01 00:00:00

abstract：AIMS:Exposure to glucose and its metabolites in peritoneal dialysis fluid (PDF) results in structural alterations of the peritoneal membrane. Icodextrin-containing PDF eliminates glucose and reduces deterioration of peritoneal membrane function, but direct effects of icodextrin molecules on peritoneal mesothelial cells...

journal_title：Life sciences

authors： Matsumoto M,Tamura M,Miyamoto T,Furuno Y,Kabashima N,Serino R,Shibata T,Kanegae K,Takeuchi M,Abe H,Okazaki M,Otsuji Y

更新日期：2012-06-14 00:00:00

abstract：:Losartan, a recently developed nonpeptide angiotensin II (Ang II) receptor antagonist, was administered orally to 10-week-old spontaneously hypertensive rats (SHR) for 2 weeks. Cardiac weight and tissue Ang II, as well as plasma renin activity (PRA) and Ang II, were determined. Treatment with Losartan (10 mg/kg per da...

journal_title：Life sciences

authors： Mizuno K,Tani M,Hashimoto S,Niimura S,Sanada H,Watanabe H,Ohtsuki M,Fukuchi S

更新日期：1992-01-01 00:00:00

abstract：AIMS:Previous investigations by our group have shown that prenatal treatment with lipopolysaccharide (LPS; 100 μg/kg, intraperitoneally) on gestation day (GD) 9.5 in rats, which mimics infections by Gram-negative bacteria, induces short- and long-term behavioral and neuroimmune changes in the offspring. Because LPS ind...

journal_title：Life sciences

authors： Galvão MC,Chaves-Kirsten GP,Queiroz-Hazarbassanov N,Carvalho VM,Bernardi MM,Kirsten TB

更新日期：2015-01-01 00:00:00

abstract：:This study was undertaken to investigate whether or not alpha 2-adrenergic pathways would negatively modulate the hypothalamic somatostatin release in rats. To induce pharmacological changes in SS release, three groups of male Sprague-Dawley rats (n = 30/group) were separately anesthetized by ip administration of uret...

journal_title：Life sciences

authors： Lima L,Arce V,Tresguerres JA,Devesa J

更新日期：1993-01-01 00:00:00

abstract：AIMS:Multiple sclerosis (MS) whose pathogenesis is still unclear is a chronic progressive disease in the central nervous system. Gut microbiota can directly or indirectly affect the immune system through the brain gut axis to engage in the occurrence and development of the disease. MATERIALS AND METHODS:C57BL/6 mice w...

journal_title：Life sciences

authors： Xu L,Zhang C,He D,Jiang N,Bai Y,Xin Y

更新日期：2020-07-15 00:00:00

abstract：:Macrophages and other host cells activated by interferon-gamma (IFN-gamma) can be induced to form a flavoprotein that converts L-arginine to nitric oxide+L-citrulline. Nitric oxide causes efflux of non-heme iron from neoplastic and infected host cells. In the absence of L-arginine, IFN-gamma-induced infected cells can...

journal_title：Life sciences

authors： Weinberg ED

更新日期：1992-01-01 00:00:00

abstract：AIMS:Hypercholesterolemia is a hazard for increasing susceptibility of the heart to myocardial infarction (MI) by inducing platelet hyperaggregability. Clopidogrel and prasugrel have documented cardioprotective effects in clinical studies. Herein, we investigated whether clopidogrel and prasugrel could protect against ...

journal_title：Life sciences

authors： Mohammad HMF,Makary S,Atef H,El-Sherbiny M,Atteia HH,Ibrahim GA,Mohamed AS,Zaitone SA

更新日期：2020-04-15 00:00:00

abstract：:Brain noradrenaline takes part in the regulation of several brain functions. The formation of brain noradrenaline depends on brain tyrosine (Tyr) levels, which associates with the ratio in plasma of Tyr to other large, neutral amino acids (LNAA). Tyr metabolism has been studied in users of the new generation combined ...

journal_title：Life sciences

authors： Møller SE,Maach-Møller B,Olesen M,Madsen B,Madsen P,Fjalland B

更新日期：1995-01-01 00:00:00

abstract：:We examined the effects of arginine-vasopressin (AVP) C-terminal fragment 4-9, which facilitates learning and memory, on the extracellular acetylcholine (ACh) release in hippocampus of freely-moving rats using the microdialysis technique. Following administration of AVP4-9, p-Glu-Asn-Cys[Cys]-Pro-Arg-Gly-NH2, through ...

journal_title：Life sciences

authors： Maegawa H,Katsube N,Okegawa T,Aishita H,Kawasaki A

更新日期：1992-01-01 00:00:00

abstract：:In adult male Wistar rats submitted to a standardized noise stress, intravenous TRH induced a prolactin (PRL) secretory response. Prior IV naloxone administration not only lowered plasma PRL levels in those stressed rats but abolished also the stimulatory action of TRH. This effect was further studied by superfusion e...

journal_title：Life sciences

authors： Velkeniers B,Buydens P,Baldys A,De Boel S,Finné E,Golstein J,Vanhaelst L

更新日期：1987-06-22 00:00:00

abstract：AIMS:Aging and drug-induced side effects may contribute to deteriorate mitochondrial bioenergetics in many tissues, including kidney and liver. One possibility is that the combination of both aging and drug toxicity accelerates the process of mitochondrial degradation, leading to progressive bioenergetic disruption. We...

journal_title：Life sciences

authors： Rocha-Rodrigues S,Santos-Alves E,Coxito PM,Marques-Aleixo I,Passos E,Guimarães JT,Martins MJ,Oliveira PJ,Magalhães J,Ascensão A

更新日期：2013-09-03 00:00:00

abstract：:Plasma 7B2-immunoreactivity (7B2-IR) concentrations in umbilical artery (UA), umbilical vein (UV) and maternal vein (MV) were measured by RIA at the time of obstetrical delivery at term. Plasma 7B2-IR concentrations (Mean +/- SEM) in UA (N = 12), UV (N = 16) and MV (N = 16) were 725 +/- 69, 699 +/- 64 and 116 +/- 4.5 ...

journal_title：Life sciences

authors： Iguchi H,Natori S,Nawata H,Kato K,Ibayashi H,Chan JS,Seidah NG,Chretien M

更新日期：1987-10-19 00:00:00

abstract：:In order to determine whether CCl4, CBrCl3, CBr4 or CHCl3 undergo oxidative metabolism to electrophilic halogens by liver microsomes, they were incubated with liver microsomes from phenobarbital pretreated rats in the presence of NADPH and 2,6-dimethylphenol. The analysis of the reaction mixtures by capillary gas chro...

journal_title：Life sciences

authors： Mico BA,Branchflower RV,Pohl LR,Pudzianowski AT,Loew GH

更新日期：1982-01-11 00:00:00

abstract：:Type-II iodothyronine 5'-deiodinase activity (5'-D) in both anterior pituitary and pineal was significantly elevated at 2400 h, approximately 0.5- and 20-fold higher than the noon value, respectively. The nocturnal rise in both organs was abolished by 6 h additional light. Short-term constant darkness did not alter 5'...

journal_title：Life sciences

authors： Murakami M,Greer MA,Greer SE,Hjulstad S,Tanaka K

更新日期：1988-01-01 00:00:00

abstract：:Since hypertension may compromise the ability to withstand hypernatremic dehydration, we investigated the impact of two experimental models of hypertension and pharmacologic normalization of blood pressure on the tolerance to chronic hypernatremic dehydration. In DOCA-salt hypertensive animals and the spontaneously-hy...

journal_title：Life sciences

authors： Trachtman H,del Pizzo R,Sturman J

更新日期：1990-01-01 00:00:00