Abstract:
:We have attempted to clarify clinical differentiating features of psychotic depression. Forty-six depressed subjects meeting DSM-III-R criteria for major depression with psychotic features were compared with (i) DSM-defined melancholic, (ii) Newcastle-defined endogenous, and (iii) a residual DSM-defined major depressive episode group. Additionally, a 'bottom up' latent class analysis (LCA) suggested a larger sample of 82 'psychotic depressive' subjects, and multivariate analyses contrasted these subjects with both LCA-identified melancholic and all residual depressed subjects. Analyses suggested that, in addition to two features with absolute specificity (delusions and hallucinations), both the DSM-defined and LCA-defined 'psychotic depressive' subjects were significantly more likely to demonstrate marked psychomotor disturbance, to report two morbid cognitions (feeling sinful and guilty; feeling deserving of punishment), as well as be more likely to report constipation, terminal insomnia, appetite/weight loss and (variable across the defined 'psychotic depressive' groups) loss of interest and pleasure. The study identifies a wider set of potentially discriminating clinical variables than previous studies, as well as both indicating the existence and assisting identification of 'true' psychotic depression in the absence of formal psychotic features being acknowledged or elicited.
journal_name
Psychol Medjournal_title
Psychological medicineauthors
Parker G,Hadzi-Pavlovic D,Brodaty H,Austin MP,Mitchell P,Wilhelm K,Hickie Idoi
10.1017/s0033291700035078subject
Has Abstractpub_date
1995-07-01 00:00:00pages
825-32issue
4eissn
0033-2917issn
1469-8978journal_volume
25pub_type
杂志文章abstract:BACKGROUND:Attention deficit hyperactivity disorder (ADHD) shows a strong phenotypic and genetic association with reaction time (RT) variability, considered to reflect lapses in attention. Yet we know little about whether this aetiological pathway is shared with other affected cognitive processes in ADHD, such as lower...
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更新日期:2012-03-01 00:00:00
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doi:10.1017/s0033291797005187
更新日期:1997-07-01 00:00:00
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更新日期:1976-11-01 00:00:00
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doi:10.1017/s0033291700002580
更新日期:1986-02-01 00:00:00
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doi:10.1017/S0033291716001057
更新日期:2016-10-01 00:00:00
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doi:10.1017/s0033291700051552
更新日期:1983-11-01 00:00:00
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doi:10.1017/S0033291718003598
更新日期:2019-05-01 00:00:00
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pub_type: 社论
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更新日期:2005-07-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2011-08-01 00:00:00
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doi:10.1017/S003329170999225X
更新日期:2010-11-01 00:00:00
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pub_type: 杂志文章
doi:10.1017/s0033291700028063
更新日期:1995-01-01 00:00:00
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pub_type: 杂志文章,meta分析,评审
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更新日期:2016-07-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291709991711
更新日期:2010-08-01 00:00:00
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更新日期:2014-09-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1017/S0033291713000949
更新日期:2013-12-01 00:00:00
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doi:10.1017/s0033291799001579
更新日期:2000-01-01 00:00:00
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pub_type: 杂志文章,meta分析
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更新日期:2019-04-01 00:00:00
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