The devil is in the detail: exploring the intrinsic neural mechanisms that link attention-deficit/hyperactivity disorder symptomatology to ongoing cognition.

abstract：BACKGROUND:The neurodevelopmental model of psychosis was established over 30 years ago; however, the developmental influence on psychotic symptom expression - how age affects clinical presentation in first-episode psychosis - has not been thoroughly investigated. METHODS:Using generalized additive modeling, which allo...

journal_title：Psychological medicine

authors： Bridgwater M,Bachman P,Tervo-Clemmens B,Haas G,Hayes R,Luna B,Salisbury DF,Jalbrzikowski M

更新日期：2020-10-06 00:00:00

abstract：BACKGROUND:Prior research suggested that time splitting--suppressing the past and dissociating it from present and future--protected refugee mental health in the aftermath of catastrophe. The current study investigates temporal reintegration, defined as cognitive recapture of the past and reconnecting it with present a...

journal_title：Psychological medicine

authors： Beiser M,Wickrama KA

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Somatoform disorders are costly for society in terms of increased healthcare expenditure. Patients' illness perceptions have been found to play a role in somatoform disorders. However, it is unclear whether illness perceptions predict higher health costs in these patients. METHOD:A total of 1785 primary car...

journal_title：Psychological medicine

authors： Frostholm L,Petrie KJ,Ornbøl E,Fink P

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Two types of mentalization-based treatment (MBT), day hospital MBT (MBT-DH) and intensive outpatient MBT (MBT-IOP), have been shown to be effective in treating patients with borderline personality disorder (BPD). This study evaluated trajectories of change in a multi-site trial of MBT-DH and MBT-IOP at 36 mo...

journal_title：Psychological medicine

authors： Smits ML,Feenstra DJ,Bales DL,Blankers M,Dekker JJM,Lucas Z,Kamphuis JH,Busschbach JJV,Verheul R,Luyten P

更新日期：2020-06-30 00:00:00

abstract：:An attempt was made to identify background, sociodemographic and clinical variables which are associated with attempted suicide in depression. Within a sample of 308 depressed psychiatric inpatients, suicide attempters were younger than non-attempters and were identified by a pattern of chronic interpersonal maladjust...

journal_title：Psychological medicine

authors： Crook T,Raskin A,Davis D

更新日期：1975-11-01 00:00:00

abstract：BACKGROUND:The Psychiatric Genomics Consortium (PGC) has made major advances in the molecular etiology of MDD, confirming that MDD is highly polygenic. Pathway enrichment results from PGC meta-analyses can also be used to help inform molecular drug targets. Prior to any knowledge of molecular biomarkers for MDD, drugs ...

journal_title：Psychological medicine

authors： Docherty AR,Moscati A,Bigdeli TB,Edwards AC,Peterson RE,Adkins DE,Anderson JS,Flint J,Kendler KS,Bacanu SA

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Cognitive models propose that auditory verbal hallucinations arise through defective self-monitoring and external attribution of inner speech. We used a paradigm that engages verbal self-monitoring to examine how deficits in this process are related to symptoms and diagnosis in patients with psychosis. METH...

journal_title：Psychological medicine

authors： Johns LC,Gregg L,Allen P,McGuire PK

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:The histological basis of schizophrenia is unknown, but it appears to affect the hippocampal and neocortical cytoarchitecture. Some cytoarchitectural parameters normally differ between the two cerebral hemispheres. Moreover, schizophrenia is associated with altered structural cerebral asymmetry. However, few...

journal_title：Psychological medicine

authors： Zaidel DW,Esiri MM,Harrison PJ

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:Executive functions have been proposed as endophenotypes for attention deficit hyperactivity disorder (ADHD); however, data regarding visual memory are lacking. We therefore assessed visual memory in adolescents with ADHD and their unaffected siblings compared with controls. METHOD:The participants included...

journal_title：Psychological medicine

authors： Shang CY,Gau SS

更新日期：2011-12-01 00:00:00

abstract：:Parental representation was assessed with the Parental Bonding Instrument (PBI) in 12 monozygotic (MZ) and 19 dizygotic (DZ) same-sexed twin pairs discordant for DSM-III-R schizophrenia. The schizophrenic twins reported less care and more overprotection from both parents than the non-schizophrenic co-twins. Multiple r...

journal_title：Psychological medicine

authors： Onstad S,Skre I,Torgersen S,Kringlen E

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND:Psychological traumatic events, such as war or road traffic accidents, are widespread. A small but significant proportion of survivors develop post-traumatic stress disorder (PTSD). Distressing, sensory-based involuntary memories of trauma (henceforth 'flashbacks') are the hallmark symptom of PTSD. Understan...

journal_title：Psychological medicine

authors： Bourne C,Mackay CE,Holmes EA

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Discriminating Alzheimer's disease (AD) and mild cognitive impairment (MCI) from depression is a challenge in psychogeriatric medicine. A study was set up to ascertain whether cued recall could be useful in differentiating early AD and MCI from depression among elderly individuals. METHOD:The Visual Associa...

journal_title：Psychological medicine

authors： Dierckx E,Engelborghs S,De Raedt R,De Deyn PP,Ponjaert-Kristoffersen I

更新日期：2007-05-01 00:00:00

abstract：:Post-traumatic stress disorder (PTSD) was studied in the Piedmont region of North Carolina. Among 2985 subjects, the lifetime and six month prevalence figures for PTSD were 1.30 and 0.44% respectively. In comparison to non-PTSD subjects, those with PTSD had significantly greater job instability, family history of psyc...

journal_title：Psychological medicine

authors： Davidson JR,Hughes D,Blazer DG,George LK

更新日期：1991-08-01 00:00:00

abstract：:Diffuse loss of cortical volume and ventricular enlargement have been demonstrated in schizophrenia using imaging. In addition, histological studies have provided evidence that the number of neurons in the medial temporal lobe structures is reduced and that the cytoarchitecture is abnormal. In an attempt to correlate ...

journal_title：Psychological medicine

authors： Maier M,Ron MA,Barker GJ,Tofts PS

更新日期：1995-11-01 00:00:00

abstract：:On the background of the recent discussion about the appropriateness of linear difference and ratio models for testing interaction effects of social support and stress, it is argued that interaction effects are basically unstable when dichotomized continuous variables are analysed. A data set with known interrelations...

journal_title：Psychological medicine

authors： Veiel HO

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND:The clinician-administered version of the Liebowitz Social Anxiety Scale (LSAS-CA) is a commonly used assessment device for the evaluation of social anxiety disorder and has been shown to have strong psychometric characteristics. Because of its apparently straightforward rating format and potential savings i...

journal_title：Psychological medicine

authors： Fresco DM,Coles ME,Heimberg RG,Liebowitz MR,Hami S,Stein MB,Goetz D

更新日期：2001-08-01 00:00:00

abstract：:Thirty-eight boys, referred for psychiatric treatment because of serious problems of behaviour, underwent a double-blind, placebo-controlled, crossover trial of methylphenidate and placebo. Methylphenidate was an effective treatment over a 3-week period. A good response to methylphenidate was predicted by higher level...

journal_title：Psychological medicine

authors： Taylor E,Schachar R,Thorley G,Wieselberg HM,Everitt B,Rutter M

更新日期：1987-02-01 00:00:00

abstract：BACKGROUND:Post-traumatic stress disorder (PTSD) has been called one of the signature injuries of the Iraq War. In this review prevalence estimates of PTSD are summarized and discrepancies are discussed in relation to methodological differences between studies. METHOD:We searched for population-based studies with a mi...

journal_title：Psychological medicine

authors： Sundin J,Fear NT,Iversen A,Rona RJ,Wessely S

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:The atypical processing of eye contact is a characteristic hallmark of autism spectrum disorder (ASD). The severity of these symptoms, however, is thought to lie on a continuum that extends into the typical population. While behavioural evidence shows that differences in social cognitive tasks in typically d...

journal_title：Psychological medicine

authors： Madipakkam AR,Rothkirch M,Dziobek I,Sterzer P

更新日期：2019-04-01 00:00:00

abstract：:The increase in plasma prolactin which follows intravenous administration of L-tryptophan (LTP) was used to assess changes in brain 5-hydroxytryptamine (5-HT) function in normal male and female subjects, following a three week period of dieting. In women, but not men, there was a marked increase in the prolactin respo...

journal_title：Psychological medicine

authors： Goodwin GM,Fairburn CG,Cowen PJ

更新日期：1987-11-01 00:00:00

abstract：BACKGROUND:Nitric oxide synthase (NOS) activity, an enzyme potentially involved in the major depressive episodes (MDE), could be indirectly measured by the L-Citrulline/L-Arginine ratio (L-Cit/L-Arg). The aim of this study was: (1) to compare the NOS activity of patients with a MDE to that of healthy controls (HC); (2)...

journal_title：Psychological medicine

authors： Loeb E,El Asmar K,Trabado S,Gressier F,Colle R,Rigal A,Martin S,Verstuyft C,Fève B,Chanson P,Becquemont L,Corruble E

更新日期：2020-06-11 00:00:00

abstract：:Recent studies have suggested that expanded CAG/CTG repeats contribute to the genetic aetiology of schizophrenia and bipolar disorder. However, the nature of this contribution is uncertain and difficult to predict from other known trinucleotide repeat diseases that display much simpler patterns of inheritance. We have...

journal_title：Psychological medicine

authors： O'Donovan MC,Guy C,Craddock N,Bowen T,McKeon P,Macedo A,Maier W,Wildenauer D,Aschauer HN,Sorbi S,Feldman E,Mynett-Johnson L,Claffey E,Nacmias B,Valente J,Dourado A,Grassi E,Lenzinger E,Heiden AM,Moorhead S,Harriso

更新日期：1996-11-01 00:00:00

abstract：:An entire population of 32 patients on regular dialysis treatment (RDT) in their own homes were ranked according to their present mental state as assessed by a standardized semi-structured interview. The point-prevalence of psychiatric morbidity was 31% which compares closely with that of patients attending a general ...

journal_title：Psychological medicine

authors： Farmer CJ,Snowden SA,Parsons V

更新日期：1979-08-01 00:00:00

abstract：BACKGROUND:The mechanisms that contribute to emotion dysregulation in anxiety disorders are not well understood. Two common disorders, generalized anxiety disorder (GAD) and panic disorder (PD), were examined to test the hypothesis that both disorders are characterized by hypo-activation in prefrontal cortex (PFC) duri...

journal_title：Psychological medicine

authors： Ball TM,Ramsawh HJ,Campbell-Sills L,Paulus MP,Stein MB

更新日期：2013-07-01 00:00:00

abstract：:The relationships among symptoms, cognitive functioning and social functioning were investigated in 60 patients with recent-onset schizophrenia. Positive symptoms were unrelated to cognitive measures. Disorganization and depressive symptoms were correlated significantly with Card Sorting performance. Furthermore, only...

journal_title：Psychological medicine

authors： Van der Does AJ,Dingemans PM,Linszen DH,Nugter MA,Scholte WF

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND:No studies have reported on how to relieve distress or relax in medical health workers while wearing medical protective equipment in coronavirus disease 2019 (COVID-19) pandemic. The study aimed to establish which relaxation technique, among six, is the most feasible in first-line medical health workers wear...

journal_title：Psychological medicine

authors： Zhang H,Li A,Zhu B,Niu Y,Ruan Z,Liu L,Gao X,Wang K,Yin L,Peng M,Xue Q,Leng H,Min B,Tian Q,Wang C,Yang Y,Zhu Z,Si T,Li W,Shangguan F,Hong X,Chang H,Song H,Li D,Jia L,Dong H,Wang Y,Cosci F,Wang H

更新日期：2020-08-24 00:00:00

abstract：BACKGROUND:Evidence from high-income countries suggests that childhood trauma is associated with schizophrenia. Studies of childhood trauma and schizophrenia in low and middle income (LMIC) countries are limited. This study examined the prevalence of childhood traumatic experiences among cases and controls and the rela...

journal_title：Psychological medicine

authors： Mall S,Platt JM,Temmingh H,Musenge E,Campbell M,Susser E,Stein DJ

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:The base rate of transition from subthreshold psychotic experiences (the exposure) to clinical psychotic disorder (the outcome) in unselected, representative and non-help-seeking population-based samples is unknown. METHOD:A systematic review and meta-analysis was conducted of representative, longitudinal p...

journal_title：Psychological medicine

authors： Kaymaz N,Drukker M,Lieb R,Wittchen HU,Werbeloff N,Weiser M,Lataster T,van Os J

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Discontinuation of antipsychotics predisposes patients with remitted/stable first-episode psychosis (FEP) to a higher risk of relapse, but it remains unclear how long discontinuation increases the relapse rate in these patients compared with maintenance. METHODS:This meta-analysis of randomized controlled t...

journal_title：Psychological medicine

authors： Kishi T,Ikuta T,Matsui Y,Inada K,Matsuda Y,Mishima K,Iwata N

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Cognitive models postulate that negative-self-schemas (NSS) cause and maintain positive symptoms and that negative affect mediates this link. However, only few studies have tested the temporal mediation claim systematically using an appropriate design. METHODS:A longitudinal cohort design in an online commu...

journal_title：Psychological medicine

authors： Jaya ES,Ascone L,Lincoln TM

更新日期：2018-06-01 00:00:00