Abstract：
:Over 250 adults and children were exposed to chlordane when the wooden building surfaces and soil around an apartment complex were sprayed in 1987. Two hundred-sixteen adults had neurobehavioral functions measured and completed questionnaires for symptom frequency, mood status, confounding factors, and medical, rheumatic, and respiratory disorders in 1994. Measurements included simple and choice reaction time, balance, blink reflex latency, color vision, cognitive, perceptual motor, memory, and recall functions. We analyzed 216 exposed and 174 referent adults. Age, educational level, weight, height, and gender ratio were similar for the exposed and referent groups. Performance of balance, reaction times, Culture Fair, digit symbol, verbal recall, and trail-making were significantly impaired in exposed persons compared to referents. Mood-state scores were elevated, as were the frequencies of respiratory, neurobehavioral, and rheumatic symptoms. In contrast, long-term memory function was similar in both groups, consistent with its status before exposure. There was no identified bias or confounding factors. Chlordane exposure was associated with protracted impairment of neurophysiological and psychological functions. The central nervous system is the most important target of chlorinated cyclodiene insecticides. Human exposure should be prohibited.
journal_name
Environ Health Perspectjournal_title
Environmental health perspectivesauthors
Kilburn KH,Thornton JCdoi
10.1289/ehp.95103690subject
Has Abstractpub_date
1995-07-01 00:00:00pages
690-4issue
7-8eissn
0091-6765issn
1552-9924journal_volume
103pub_type
杂志文章abstract：BACKGROUND:Psychological sequelae are among the most pronounced effects in populations following exposure to oil spills. Women in particular represent a vulnerable yet influential population but have remained relatively understudied with respect to the Deepwater Horizon oil spill (DHOS). OBJECTIVE:To describe the rela...
journal_title：Environmental health perspectives
pub_type： 杂志文章
doi：10.1289/EHP167
更新日期：2016-09-01 00:00:00
abstract：BACKGROUND:Prostaglandins (PGs) play key roles in development and maintenance of homeostasis of the adult body. Despite these important roles, it remains unclear whether the PG pathway is a target for endocrine disruption. However, several known endocrine-disrupting compounds (EDCs) share a high degree of structural si...
journal_title：Environmental health perspectives
pub_type： 杂志文章
doi：10.1289/ehp.1002635
更新日期：2011-04-01 00:00:00
abstract：:In numerous in vivo systems it has been shown that diets high in menhaden oil (a fish oil high in omega-3 fatty acids) can inhibit the carcinogenic process. In the present study, we have assessed the effects of a diet containing menhaden oil on 2-amino-3-methylimidazo[4,5-f]quinoline (IQ)-DNA adduct formation in targe...
journal_title：Environmental health perspectives
pub_type： 杂志文章
doi：10.1289/ehp.94102s657
更新日期：1994-10-01 00:00:00
abstract：:Occupational and environmental asbestos exposure continues to represent a public health problem, despite increasingly restrictive laws adopted by most industrialized countries. Peritoneal mesothelioma is a rare and aggressive asbestos-related malignancy. We present the case of a 65-year-old man who developed recurrent...
journal_title：Environmental health perspectives
pub_type： 杂志文章
doi：10.1289/ehp.6542
更新日期：2004-04-01 00:00:00
abstract：:Lead, cadmium, mercury, and arsenic are common environmental pollutants in industrialized countries, but their combined impact on children's health is little known. We studied their effects on two main targets, the renal and dopaminergic systems, in > 800 children during a cross-sectional European survey. Control and ...
journal_title：Environmental health perspectives
pub_type： 杂志文章
doi：10.1289/ehp.8202
更新日期：2006-04-01 00:00:00
abstract：:A biodosimetric approach to determine alpha-particle dose to the respiratory tract epithelium from known exposures to radon has been developed in the rat. Cytotoxicity assays have been used to obtain dose-conversion factors for cumulative exposures typical of those encountered by underground uranium miners. However, t...
journal_title：Environmental health perspectives
pub_type： 杂志文章
doi：10.1289/ehp.97105s4913
更新日期：1997-06-01 00:00:00
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journal_title：Environmental health perspectives
pub_type： 杂志文章
doi：10.1289/ehp.95103936
更新日期：1995-10-01 00:00:00
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journal_title：Environmental health perspectives
pub_type： 杂志文章
doi：10.1289/ehp.1308038
更新日期：2014-12-01 00:00:00
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journal_title：Environmental health perspectives
pub_type： 杂志文章,评审
doi：10.1289/EHP1465
更新日期：2017-03-01 00:00:00
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journal_title：Environmental health perspectives
pub_type： 杂志文章
doi：10.1289/ehp.6560
更新日期：2004-02-01 00:00:00
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journal_title：Environmental health perspectives
pub_type： 杂志文章
doi：10.1289/ehp.9399129
更新日期：1993-03-01 00:00:00
abstract：:The three modern "faces" of mercury are our perceptions of risk from the exposure of billions of people to methyl mercury in fish, mercury vapor from amalgam tooth fillings, and ethyl mercury in the form of thimerosal added as an antiseptic to widely used vaccines. In this article I review human exposure to and the to...
journal_title：Environmental health perspectives
pub_type： 杂志文章,评审
doi：10.1289/ehp.02110s111
更新日期：2002-02-01 00:00:00
abstract：OBJECTIVE:This study was designed to determine whether prenatal mercury exposure, including potential releases from the World Trade Center (WTC) disaster, adversely affects fetal growth and child development. METHODS:We determined maternal and umbilical cord blood total mercury of nonsmoking women who delivered at ter...
journal_title：Environmental health perspectives
pub_type： 杂志文章
doi：10.1289/ehp.10831
更新日期：2008-08-01 00:00:00
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journal_title：Environmental health perspectives
pub_type： 杂志文章
doi：10.1289/ehp.4980
更新日期：2003-02-01 00:00:00
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journal_title：Environmental health perspectives
pub_type： 杂志文章
doi：10.1289/ehp.02110591
更新日期：2002-06-01 00:00:00
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journal_title：Environmental health perspectives
pub_type： 杂志文章
doi：
更新日期：2006-05-01 00:00:00
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journal_title：Environmental health perspectives
pub_type： 杂志文章
doi：10.1289/ehp.0800511
更新日期：2009-09-01 00:00:00
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journal_title：Environmental health perspectives
pub_type： 杂志文章,评审
doi：10.1289/ehp.8990
更新日期：2007-06-01 00:00:00
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journal_title：Environmental health perspectives
pub_type： 杂志文章
doi：10.1289/ehp.98106s61419
更新日期：1998-12-01 00:00:00
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journal_title：Environmental health perspectives
pub_type： 杂志文章
doi：10.1289/ehp.96104s2173
更新日期：1996-04-01 00:00:00
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journal_title：Environmental health perspectives
pub_type： 杂志文章
doi：10.1289/ehp.11339
更新日期：2008-10-01 00:00:00
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journal_title：Environmental health perspectives
pub_type： 杂志文章
doi：10.1289/ehp.866989
更新日期：1986-11-01 00:00:00
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journal_title：Environmental health perspectives
pub_type： 杂志文章
doi：10.1289/ehp.7617227
更新日期：1976-10-01 00:00:00
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journal_title：Environmental health perspectives
pub_type： 杂志文章
doi：10.1289/ehp.11449
更新日期：2008-12-01 00:00:00
abstract：:Polychlorinated biphenyls (PCBs) and dioxins are known as neurotoxic compounds that may modulate sex steroid hormones. Steroid hormones play a mediating role in brain development and may influence behaviors that show sex differences, such as childhood play behavior. In this study we evaluated the effects of perinatal ...
journal_title：Environmental health perspectives
pub_type： 杂志文章
doi：10.1289/ehp.021100593
更新日期：2002-10-01 00:00:00
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journal_title：Environmental health perspectives
pub_type： 杂志文章
doi：10.1289/ehp.1206039
更新日期：2013-03-01 00:00:00
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journal_title：Environmental health perspectives
pub_type： 杂志文章
doi：10.1289/ehp.771943
更新日期：1977-08-01 00:00:00
abstract：BACKGROUND:Bacterial meningitis causes a high burden of disease in the African meningitis belt, with regular seasonal hyperendemicity and sporadic short, but intense, localized epidemics during the late dry season occurring at a small spatial scale [i.e., below the district level, in individual health centers (HCs)]. I...
journal_title：Environmental health perspectives
pub_type： 杂志文章
doi：10.1289/EHP2752
更新日期：2018-09-01 00:00:00
abstract：:This paper summarizes the clinical phenomenology of multiple chemical sensitivity (MCS), outlines the concepts and evidence for the olfactory-limbic, neural sensitization model for MCS, and discusses experimental design implications of the model for exposure-related research. Neural sensitization is the progressive am...
journal_title：Environmental health perspectives
pub_type： 杂志文章,评审
doi：10.1289/ehp.97105s2457
更新日期：1997-03-01 00:00:00
abstract：BACKGROUND:Drinking water contamination related to the use of aqueous film-forming foam (AFFF) has been documented at hundreds of military bases, airports, and firefighter training facilities. AFFF has historically contained high levels of long-chain per- and polyfluoroalkyl substances (PFAS), which pose serious health...
journal_title：Environmental health perspectives
pub_type： 杂志文章
doi：10.1289/EHP6470
更新日期：2020-09-01 00:00:00
