Diffusion of residual monomer in polymer resins.

abstract：:Lead is a male reproductive toxicant. Data suggest that rats dosed with relatively high levels of lead acetate for short periods of time induced changes in the hypothalamic gonadotropin-releasing hormone (GnRH) at the molecular level, but these changes were attenuated with increased concentration of exposure. The curr...

journal_title：Environmental health perspectives

authors： Sokol RZ,Wang S,Wan YJ,Stanczyk FZ,Gentzschein E,Chapin RE

更新日期：2002-09-01 00:00:00

abstract：:In this article we report a simple and efficient method for detecting nonsteroidal estrogens in a biologic sample. This method uses polyclonal antibodies to estradiol (E2) to immunoprecipitate these major biologically active steroidal estrogens, leaving behind the nonsteroidal estrogens, which are then detected in a c...

journal_title：Environmental health perspectives

authors： Natarajan K,Overstreet JW,Rogers JM,Denison MS,Chen J,Lohstroh PN,McConnell DS,Lasley BL

更新日期：2002-08-01 00:00:00

abstract：:Erythropoietic cells in bone marrow are vulnerable to cytotoxic substances. There are three types of erythroid precursors: cells that can take up Fe but do not proliferate (reticulocytes), those that can take up Fe and proliferate (normoblasts and pronormoblasts), and those cells that do not take up Fe but can prolife...

journal_title：Environmental health perspectives

authors： Lee EW,Kocsis JJ,Snyder R

更新日期：1981-06-01 00:00:00

abstract：BACKGROUND:The toxicity of many xenobiotic compounds is believed to involve oxidative injury to cells. Direct assessment of mechanistic events involved in xenobiotic-induced oxidative stress is not easily achievable. Development of genetically encoded probes designed for monitoring intracellular redox changes represent...

journal_title：Environmental health perspectives

authors： Gibbs-Flournoy EA,Simmons SO,Bromberg PA,Dick TP,Samet JM

更新日期：2013-03-01 00:00:00

abstract：:Fanconi anemia (FA) is an autosomal recessive disorder characterized by diverse developmental abnormalities, progressive bone marrow failure, and a markedly increased incidence of malignancy. FA cells are hypersensitive to DNA cross-linking agents, suggesting a general defect in the repair of DNA cross-links. Some for...

journal_title：Environmental health perspectives

authors： Vilcheck SK,O'Brien TJ,Pritchard DE,Ha L,Ceryak S,Fornsaglio JL,Patierno SR

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Traffic noise affects a large number of people, particularly in urbanized areas. Noise causes stress and annoyance, but less is known about the relationship between noise and depression. OBJECTIVE:We investigated the association of residential road traffic noise with depressive symptoms using 5-year follow-...

journal_title：Environmental health perspectives

authors： Orban E,McDonald K,Sutcliffe R,Hoffmann B,Fuks KB,Dragano N,Viehmann A,Erbel R,Jöckel KH,Pundt N,Moebus S

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Exposure to organophosphate (OP) pesticides is an occupational hazard for farmworkers and affects their children through the take-home pathway. OBJECTIVES:We examined the effectiveness of a randomized community intervention to reduce pesticide exposure among farmworkers and their children. METHODS:We condu...

journal_title：Environmental health perspectives

authors： Thompson B,Coronado GD,Vigoren EM,Griffith WC,Fenske RA,Kissel JC,Shirai JH,Faustman EM

更新日期：2008-05-01 00:00:00

abstract：:Syrian hamster embryo cells were treated with galactose oxidase, followed by reduction with tritiated sodium borohydride at pH 7.4. The labeling patterns of galactosyl and N-acetyl galactosaminyl residues on the cell surface were altered in comparing scraped vs. unscraped and buffer vs. media-soaked cells treated with...

journal_title：Environmental health perspectives

authors： Newman HA,Saat YA,Hart RW

更新日期：1980-02-01 00:00:00

abstract：:The Sertoli cell is the primary target for FSH action in the mammalian testis. These cells contain the majority of testicular plasma membrane receptors for this hormone. Receptor occupancy is directly correlated with a stimulation of adenylyl cyclase and a decrease in the activity of a cytoplasmic Ca++-sensitive cAMP ...

journal_title：Environmental health perspectives

authors： Tindall DJ,Tash JS,Means AR

更新日期：1981-04-01 00:00:00

abstract：BACKGROUND:Microcystin-LR, a cyclic heptapeptide, possesses the ability to inhibit the serine/threonine protein phosphatases PP1 and PP2A and, consequently, exhibits acute hepatocytotoxicity. Moreover, microcystin-LR induces cellular proliferation, resulting in tumor-promoting activity in hepatocytes. However, mechanis...

journal_title：Environmental health perspectives

authors： Takumi S,Komatsu M,Furukawa T,Ikeda R,Sumizawa T,Akenaga H,Maeda Y,Aoyama K,Arizono K,Ando S,Takeuchi T

更新日期：2010-09-01 00:00:00

abstract：:Metal ions form complexes with naturally occurring complexing agents or ligands released from industrial activity. The metal complexes are thereby mobilized and transported in environmental and biological systems. The impact of such metal complexes depends on the metal complex species that are kinetically and thermody...

journal_title：Environmental health perspectives

authors： Fernando Q

更新日期：1995-02-01 00:00:00

abstract：BACKGROUND:Mortality displacement (or "harvesting") has been identified as a key issue in the assessment of the temperature-mortality relationship. However, only a few studies have addressed the "harvesting" issue and findings have not been consistent. OBJECTIVES:We examined the potential impact of both short- and lon...

journal_title：Environmental health perspectives

authors： Qiao Z,Guo Y,Yu W,Tong S

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Ambient air ozone (O3) is a pulmonary irritant that has been associated with respiratory health effects including increased lung inflammation and permeability, airway hyperreactivity, respiratory symptoms, and decreased lung function. Estimation of O3 exposure is a complex task because the pollutant exhibits...

journal_title：Environmental health perspectives

authors： Adam-Poupart A,Brand A,Fournier M,Jerrett M,Smargiassi A

更新日期：2014-09-01 00:00:00

abstract：:Three to 4 million children and adolescents in the United States live within 1 mile of a federally designated Superfund hazardous waste disposal site and are at risk of exposure to chemical toxicants released from these sites into air, groundwater, surface water, and surrounding communities. Because of their patterns ...

journal_title：Environmental health perspectives

authors： Landrigan PJ,Suk WA,Amler RW

更新日期：1999-06-01 00:00:00

abstract：:We assessed chlorinated hydrocarbon contamination of mink and river otters on the Columbia and Fraser River systems of northwestern North America, in relation to morphological measures of condition. We obtained carcasses of mink and river otters from commercial trappers during the winters 1994-1995 and 1995-1996. Necr...

journal_title：Environmental health perspectives

authors： Harding LE,Harris ML,Stephen CR,Elliott JE

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:Bisphenol A (BPA) is known to be biologically active in experimental models even at low levels of exposure. However, its impact on endometrial cancer remains unclear. OBJECTIVES:This study aimed to investigate whether lifelong exposure to different doses of BPA induced uterine abnormalities and molecular ch...

journal_title：Environmental health perspectives

authors： Leung YK,Biesiada J,Govindarajah V,Ying J,Kendler A,Medvedovic M,Ho SM

更新日期：2020-12-01 00:00:00

abstract：:The past and current EPA research and regulatory programs as they relate to non-regulated emissions from light-duty motor vehicles are reviewed. Provisions of Sections 202(a) and 211 of the 1970 Clean Air Act Amendments are discussed and their relationships to the nonregulated emissions issue detailed. The EPA positio...

journal_title：Environmental health perspectives

authors： Moran JB

更新日期：1975-04-01 00:00:00

abstract：:Carbon monoxide is widely distributed in the environment, and acute or chronic toxic effects may be of considerable public health significance. A review of the basis for current ambient standards is given. Mortality and morbidity studies have been negative or equivocal in relating carbon monoxide levels to health effe...

journal_title：Environmental health perspectives

authors： Kuller LH,Radford EP

更新日期：1983-10-01 00:00:00

abstract：:Ambient monitoring of acid aerosols in four U.S. cities and in a rural region of southern Ontario clearly show distinct periods of strong acidity. Measurements made in Kingston, TN, and Steubenville, OH, resulted in 24-hr H+ ion concentrations exceeding 100 nmole/m3 more than 10 times during summer months. Periods of ...

journal_title：Environmental health perspectives

authors： Spengler JD,Keeler GJ,Koutrakis P,Ryan PB,Raizenne M,Franklin CA

更新日期：1989-02-01 00:00:00

abstract：:Environmental health and environmental quality issues along the U.S.-Mexico border have been of concern for several years. The enactment of the North American Free Trade Agreement and the presence of the maquiladoras (foreign-owned industries using imported raw materials) have intensified those concerns recently. Effo...

journal_title：Environmental health perspectives

authors： Carter DE,Peña C,Varady R,Suk WA

更新日期：1996-06-01 00:00:00

abstract：:Consideration of needs for public health interventions and new research requires comparative assessments of the health benefits that are likely to result from alternative uses of limited regulatory and technical resources. This paper briefly examines regulatory and research priorities in the light of recent informatio...

journal_title：Environmental health perspectives

authors： Hattis D

更新日期：1981-10-01 00:00:00

abstract：BACKGROUND:Cigarette smoke exposure in utero and during early postnatal development increases the incidence of asthma and airway hyperresponsiveness (AHR) later in life, suggesting that a possible critical period of developmental sensitivity exists in the prenatal and early postnatal periods. OBJECTIVE:We investigated...

journal_title：Environmental health perspectives

authors： Wu ZX,Hunter DD,Kish VL,Benders KM,Batchelor TP,Dey RD

更新日期：2009-09-01 00:00:00

abstract：:Individual variability in human arsenic metabolism has been reported frequently in the literature. This variability could be an underlying determinant of individual susceptibility to arsenic-induced disease in humans. Recent analysis revealing familial aggregation of arsenic metabolic profiles suggests that genetic fa...

journal_title：Environmental health perspectives

authors： Yu L,Kalla K,Guthrie E,Vidrine A,Klimecki WT

更新日期：2003-08-01 00:00:00

abstract：:The Tradescantia genetic system developed by the late Dr. Arnold H. Sparrow for the study of effects of ionizing radiation is applicable to chemical mutagen detection. Early radiobiological data demonstrated that the stamen hairs were sensitive to as little as 0.25 rad of x-rays and that the number of cells showing a ...

journal_title：Environmental health perspectives

authors： Schairer LA,Van't Hof J,Hayes CG,Burton RM,de Serres FJ

更新日期：1978-12-01 00:00:00

abstract：:There is a significant public health concern about the potential effects of occupational exposure to toxic substances on reproductive outcomes. Several toxicants with reported reproductive and developmental effects are still in regular commercial or therapeutic use and thus present potential exposure to workers. Examp...

journal_title：Environmental health perspectives

authors： Lawson CC,Schnorr TM,Daston GP,Grajewski B,Marcus M,McDiarmid M,Murono E,Perreault SD,Schrader SM,Shelby M

更新日期：2003-04-01 00:00:00

abstract：:The assessment of mixture effects of estrogenic agents is regarded as an issue of high priority by many governmental agencies and expert decision-making bodies all over the world. However, the few mixture studies published so far have suffered from conceptual and experimental problems and are considered to be inconclu...

journal_title：Environmental health perspectives

authors： Payne J,Rajapakse N,Wilkins M,Kortenkamp A

更新日期：2000-10-01 00:00:00

abstract：:A comparative analysis was performed of the phenotype and function of peripheral blood leukocytes of two age-matched cohorts of industrial workers in chemical plants, one of which was exposed occupationally to high concentrations of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Median actual TCDD burdens were 116 ng/kg ...

journal_title：Environmental health perspectives

authors： Ernst M,Flesch-Janys D,Morgenstern I,Manz A

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND:The damaging effects of exposure to environmental toxicants differentially affect genetically distinct individuals, but the mechanisms contributing to these differences are poorly understood. Genetic variation affects the establishment of the gene regulatory landscape and thus gene expression, and we hypothe...

journal_title：Environmental health perspectives

authors： Chappell GA,Israel JW,Simon JM,Pott S,Safi A,Eklund K,Sexton KG,Bodnar W,Lieb JD,Crawford GE,Rusyn I,Furey TS

更新日期：2017-10-16 00:00:00

abstract：:In an attempt to elucidate the relationship between DNA adduct formation and tumorigenesis, DNA adducts were measured in the livers and bladders of mice during chronic exposure to several different doses of 2-acetylaminofluorene (2-AAF) and 4-aminobiphenyl (4-ABP). Continuous oral administration of these compounds for...

journal_title：Environmental health perspectives

authors： Poirier MC,Beland FA

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:Lead (Pb) exposure has been associated with a host of pathological conditions in humans. In rodents Pb exposure has been shown to alter the hypothalamic-pituitary-adrenal (HPA) axis function. OBJECTIVE:We investigated the effects of lead on responses of the HPA axis to a psychosocial laboratory stressor adm...

journal_title：Environmental health perspectives

authors： Fortin MC,Cory-Slechta DA,Ohman-Strickland P,Nwankwo C,Yanger TS,Todd AC,Moynihan J,Walton J,Brooks A,Fiedler N

更新日期：2012-02-01 00:00:00