Mortality in the Medicare population and chronic exposure to fine particulate air pollution in urban centers (2000-2005).

abstract：BACKGROUND:High-level occupational exposures to some industrial chemicals have been associated with liver diseases, including nonalcoholic fatty liver disease (NAFLD). However, the potential role of low-level environmental pollution on liver disease in the general population has not been evaluated. OBJECTIVE:We determ...

journal_title：Environmental health perspectives

authors： Cave M,Appana S,Patel M,Falkner KC,McClain CJ,Brock G

更新日期：2010-12-01 00:00:00

abstract：:A brief description of chromosome aberrations and sister chromatid exchange (SCE) as cytogenetic endpoints for evaluation of DNA damaging agents is presented. Problems associated with the use of cytogenetic assays as population monitors of radiation and chemical exposures are discussed. Adequate cell sample size requi...

journal_title：Environmental health perspectives

authors： Conner MK,Wald N

更新日期：1981-12-01 00:00:00

abstract：:Nationwide, 45 states issue health advisories for sport fish consumers. Chemical contaminants in some Great Lakes (GL) sport fish include compounds suspected of causing adverse reproductive and developmental effects. Although advisories to reduce consumption of contaminated fish, especially by women, have been issued ...

journal_title：Environmental health perspectives

authors： Tilden J,Hanrahan LP,Anderson H,Palit C,Olson J,Kenzie WM

更新日期：1997-12-01 00:00:00

abstract：BACKGROUND:Whether there is a causal relation between long-term exposure to traffic and asthma development is so far not clear. This may be explained by inaccurate exposure assessment. OBJECTIVE:We investigated the associations of long-term traffic-related exposures with asthma onset assessed retrospectively and respi...

journal_title：Environmental health perspectives

authors： Oftedal B,Nystad W,Brunekreef B,Nafstad P

更新日期：2009-05-01 00:00:00

abstract：:The type II cell plays an important role in the response of the alveolar epithelium after lung injury through its synthesis and secretion of pulmonary surfactant, and by acting as the stem cell for the replacement of damaged type I epithelial cells. The nonciliated bronchiolar epithelial (Clara) cell is thought to pla...

journal_title：Environmental health perspectives

authors： Finkelstein JN,Johnston C,Barrett T,Oberdörster G

更新日期：1997-09-01 00:00:00

abstract：:Epidemiological studies examining the association between exposure to tap water contaminants (such as chlorination by-products) and disease outcomes (such as cancer and adverse reproductive outcomes) have been limited by inaccurate exposure assessment. Failure to take into account the variation in beverage and tap wat...

journal_title：Environmental health perspectives

authors： Shimokura GH,Savitz DA,Symanski E

更新日期：1998-02-01 00:00:00

abstract：:Articles in the literature on alpha-1 antitrypsin (AAT) deficiency have been interpreted as indicating that AAT deficiency is a rare disease that affects mainly Caucasians (whites) from northern Europe. In a recent publication on the worldwide racial and ethnic distribution of AAT deficiency, new data were presented d...

journal_title：Environmental health perspectives

authors： de Serres FJ

更新日期：2003-12-01 00:00:00

abstract：:This article briefly summarizes the epidemiology of the health effects of fine particulate air pollution, provides an early, somewhat speculative, discussion of the contribution of epidemiology to evaluating biologic mechanisms, and evaluates who's at risk or is susceptible to adverse health effects. Based on prelimin...

journal_title：Environmental health perspectives

authors： Pope CA 3rd

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:The impact of prenatal lead exposure on neurodevelopment remains unclear in terms of consistency, the trimester of greatest vulnerability, and the best method for estimating fetal lead exposure. OBJECTIVE:We studied prenatal lead exposure's impact on neurodevelopment using repeated measures of fetal dose as...

journal_title：Environmental health perspectives

authors： Hu H,Téllez-Rojo MM,Bellinger D,Smith D,Ettinger AS,Lamadrid-Figueroa H,Schwartz J,Schnaas L,Mercado-García A,Hernández-Avila M

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Use of pyrethroid insecticides has increased dramatically over the past decade; however, data on their potential health effects, particularly on children, are limited. OBJECTIVE:We examined the cross-sectional association between postnatal pyrethroid exposure and parental report of learning disability (LD) ...

journal_title：Environmental health perspectives

authors： Quirós-Alcalá L,Mehta S,Eskenazi B

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Few studies have been conducted to identify risk factors for balance and vestibular dysfunction in general populations, but previous studies have reported evidence of adverse effects of lead and cadmium on balance control in high-risk groups. OBJECTIVE:We evaluated the relationship between blood lead and ca...

journal_title：Environmental health perspectives

authors： Min KB,Lee KJ,Park JB,Min JY

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:In animals, some phthalates impair male reproductive development and function. Epidemiological studies have reported inconsistent evidence of associations between phthalates and markers of human testicular function. OBJECTIVES:We aimed to provide estimates of the effects of phthalate exposure on reproductiv...

journal_title：Environmental health perspectives

authors： Joensen UN,Frederiksen H,Blomberg Jensen M,Lauritsen MP,Olesen IA,Lassen TH,Andersson AM,Jørgensen N

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Bisphenol A (BPA) is widely used in the manufacture of polycarbonate plastic bottles, food and beverage can linings, thermal receipts, and dental sealants. Animal and human studies suggest that BPA may disrupt thyroid function. Although thyroid hormones play a determinant role in human growth and brain devel...

journal_title：Environmental health perspectives

authors： Chevrier J,Gunier RB,Bradman A,Holland NT,Calafat AM,Eskenazi B,Harley KG

更新日期：2013-01-01 00:00:00

abstract：:In this article we summarize the results of a series of studies that measured the relative bioavailability (RBA) of lead in a variety of soil and soil-like test materials. Reference material (Pb acetate) or Pb-contaminated soils were administered orally to juvenile swine twice a day for 15 days. Blood samples were col...

journal_title：Environmental health perspectives

authors： Casteel SW,Weis CP,Henningsen GM,Brattin WJ

更新日期：2006-08-01 00:00:00

abstract：:Building-related illness ranges from mild rhinitis to potentially life-threatening hypersensitivity pneumonitis and legionellosis. Sick-building syndrome, consisting of headache, mucous membrane irritation, and fatigue, may be present in 30% of all office workers. Hypersensitivity pneumonitis, asthma, and legionellosi...

journal_title：Environmental health perspectives

authors： Welch LS

更新日期：1991-11-01 00:00:00

abstract：:The effects of global change on biodiversity and ecosystem functioning encompass multiple complex dynamic processes. Climate change and exposure to endocrine-disrupting chemicals (EDCs) are currently regarded as two of the most serious anthropogenic threats to biodiversity and ecosystems. We should, therefore, be espe...

journal_title：Environmental health perspectives

authors： Jenssen BM

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:Epidemiologic studies have demonstrated that occupational noise exposure is associated with hypertension, but the related mechanism in vascular structural changes is unclear. OBJECTIVE:This panel study aimed to investigate effects of occupational noise exposure on ambulatory vascular structural properties i...

journal_title：Environmental health perspectives

authors： Chang TY,Su TC,Lin SY,Jain RM,Chan CC

更新日期：2007-11-01 00:00:00

abstract：:Three to 4 million children and adolescents in the United States live within 1 mile of a federally designated Superfund hazardous waste disposal site and are at risk of exposure to chemical toxicants released from these sites into air, groundwater, surface water, and surrounding communities. Because of their patterns ...

journal_title：Environmental health perspectives

authors： Landrigan PJ,Suk WA,Amler RW

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:Policy decisions regarding climate change mitigation are increasingly incorporating the beneficial and adverse health impacts of greenhouse gas emission reduction strategies. Studies of such co-benefits and co-harms involve modeling approaches requiring a range of analytic decisions that affect the model out...

journal_title：Environmental health perspectives

authors： Remais JV,Hess JJ,Ebi KL,Markandya A,Balbus JM,Wilkinson P,Haines A,Chalabi Z

更新日期：2014-05-01 00:00:00

abstract：:We examined 100 symptomatic Gulf War veterans (patients) and 100 controls for immunologic assays. The veterans and controls were compared for the percentage of T cells (CD3); B cells (CD19); helper:suppressor (CD4:CD8) ratio; natural killer (NK) cell activity; mitogenic response to phytohemagglutin (PHA) and pokeweed ...

journal_title：Environmental health perspectives

authors： Vojdani A,Thrasher JD

更新日期：2004-06-01 00:00:00

abstract：:A major concern of the chlorination of aquatic humic materials is the ubiquitous production of trihalomethanes. A large number of other chlorinated organic compounds, however, have been shown to be formed by chlorine's reaction with humic substances. In this study, humic material was concentrated from a coastal North ...

journal_title：Environmental health perspectives

authors： Johnson JD,Christman RF,Norwood DL,Millington DS

更新日期：1982-12-01 00:00:00

abstract：:It is necessary but not sufficient to develop laboratory animal models in sensory behavioral toxicology for screening toxic substances and for the analysis of sensory impairment at threshold levels of stimulation. It is important to develop more thorough and quantitative tests of impairment which in their greater comp...

journal_title：Environmental health perspectives

authors： Stebbins WC

更新日期：1982-04-01 00:00:00

abstract：:The types of biological response to an environmental agent can depend on dose, thus in this case a family of widely different dose-response relationships would be expected. For those situations where the magnitude of the effect may be determined on probabilistic grounds as a function of dose ("stochastic" model), no p...

journal_title：Environmental health perspectives

authors： Radford EP

更新日期：1981-12-01 00:00:00

abstract：:An estimated 8000 children 0 to 14 years of age are diagnosed annually with cancer in the United States. Leukemia and brain tumors are the most common childhood malignancies, accounting for 30 and 20% of newly diagnosed cases, respectively. From 1975 to 1978 to 1987 to 1990, cancer among white children increased sligh...

journal_title：Environmental health perspectives

authors： Zahm SH,Devesa SS

更新日期：1995-09-01 00:00:00

abstract：:Fumonisin B1(FB1) is a fungal metabolite of Fusarium verticillioides (= F. moniliforme), a fungus that grows on many crops worldwide. Previous studies demonstrated that male BD IX rats consuming diets containing 50 ppm fumonisin B1 developed hepatocellular carcinomas. In our recent studies, diets containing FB1 at 50 ...

journal_title：Environmental health perspectives

authors： Howard PC,Warbritton A,Voss KA,Lorentzen RJ,Thurman JD,Kovach RM,Bucci TJ

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Miners inhaling respirable coal dust (CD) frequently develop coal workers' pneumoconiosis, a dust-associated pneumoconiosis characterized by lung inflammation and variable fibrosis. Many coal miners are also exposed to polycyclic aromatic hydrocarbon (PAH) components of diesel engine exhaust and cigarette sm...

journal_title：Environmental health perspectives

authors： Ghanem MM,Battelli LA,Mercer RR,Scabilloni JF,Kashon ML,Ma JY,Nath J,Hubbs AF

更新日期：2006-09-01 00:00:00

abstract：:Previous investigations suggest that dietary sources of polycyclic aromatic hydrocarbons (PAHs) contribute to the PAH-DNA adduct load in peripheral white blood cells (WBCs). In the current study, we measured PAH-DNA adducts by enzyme-linked immunosorbent assay in WBCs obtained from 47 California wildland (forest) fire...

journal_title：Environmental health perspectives

authors： Rothman N,Poirier MC,Haas RA,Correa-Villasenor A,Ford P,Hansen JA,O'Toole T,Strickland PT

更新日期：1993-03-01 00:00:00

abstract：:The unique nonrespiratory functions of the lungs have become more apparent in recent years. The isolated perfused lung model offers many advantages over other methods for the study of pulmonary metabolism, xenobiotic disposition and the influence of interactions among agents of different physical forms. Detailed descr...

journal_title：Environmental health perspectives

authors： Niemeier RW

更新日期：1984-06-01 00:00:00

abstract：:Low-dose extrapolation model selection for evaluating the health effects of environmental pollutants is a key component of the risk assessment process. At a workshop held in Baltimore, Maryland, on 23-24 April 2007, sponsored by U.S. Environmental Protection Agency and Johns Hopkins Risk Sciences and Public Policy Ins...

journal_title：Environmental health perspectives

authors： White RH,Cote I,Zeise L,Fox M,Dominici F,Burke TA,White PD,Hattis DB,Samet JM

更新日期：2009-02-01 00:00:00

abstract：:The remarkable frequency of uterine leiomyoma in the human population calls into question the potential for the participation of environmental factors in tumor etiology. Having been implicated in the dramatic rise in hormone-related cancers in recent years, endocrine disruptors are salient suspects in this pathogenesi...

journal_title：Environmental health perspectives

authors： Hunter DS,Hodges LC,Eagon PK,Vonier PM,Fuchs-Young R,Bergerson JS,Walker CL

更新日期：2000-10-01 00:00:00