Pagetoid dyskeratosis: a selective keratinocytic response.

abstract：:POEMS syndrome is an unusual plasma cell dyscrasia with multisystemic manifestations featuring polyneuropathy, organomegaly, endocrinopathy, M protein and constant skin involvement. We have seen a 58-year-old white man presenting with generalized eruptive angiomas as a rare skin manifestation of this syndrome. We revi...

journal_title：Journal of the American Academy of Dermatology

authors： Puig L,Moreno A,Domingo P,Llistosella E,de Moragas JM

更新日期：1985-05-01 00:00:00

abstract：:We used an avidin-biotin complex immunoperoxidase technique with various monoclonal antibodies to determine Langerhans cell densities, class II antigen expression on keratinocytes, and phenotypes of other infiltrating cells in several malignant and benign epithelial tumors of the skin. Our observations indicate (1) th...

journal_title：Journal of the American Academy of Dermatology

authors： Chen HD,Zhao YM,Sun G,Yang CY

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND:Early specialist evaluation during rapid proliferative growth of complicated infantile hemangiomas (IH) is crucial. Health disparities and barriers of access-to-care for children with IH have not been examined. OBJECTIVE:Investigate whether socioeconomic status (SES) is associated with age at subspecialist ...

journal_title：Journal of the American Academy of Dermatology

authors： Lie E,Psoter KJ,Püttgen KB

更新日期：2018-10-01 00:00:00

abstract：:A series of thirty-eight cases of congenital nevocellular nevi were excised and studied histologically. Depending on the extent of nevoid cell dermal infiltration, four histologic patterns were observed: diffuse or patchy infiltration of the upper dermis alone, or diffuse or patchy infiltration of the upper and deep d...

journal_title：Journal of the American Academy of Dermatology

authors： Stenn KS,Arons M,Hurwitz S

更新日期：1983-09-01 00:00:00

abstract：:Fifteen children who had foot dermatitis were evaluated by examinations with potassium hydroxide and fungal cultures. In eight cases dermatophyte infection was identified. Tinea pedis in prepubertal children is more common than previously reported. ...

journal_title：Journal of the American Academy of Dermatology

authors： Kearse HL,Miller OF 3rd

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND:Previous studies have demonstrated that patients with psoriasis may have an increased risk of a variety of noncutaneous diseases, including arterial and venous occlusive diseases. Changes in plasma lipid and lipoprotein composition in patients with psoriasis may be the reason for the increased risk of athero...

journal_title：Journal of the American Academy of Dermatology

authors： Seçkin D,Tokgözoğlu L,Akkaya S

更新日期：1994-09-01 00:00:00

abstract：:Pigmentary demarcation lines are borders of abrupt transition between more deeply pigmented skin and that of lighter pigmentation. Two patients developed these lines on the lower extremities during pregnancy. ...

journal_title：Journal of the American Academy of Dermatology

authors： James WD,Meltzer MS,Guill MA,Berger TG,Rodman OG

更新日期：1984-09-01 00:00:00

abstract：:This report reflects the best data available at the time the report was prepared, but caution should be exercised in interpreting the data; the results of future studies may require alteration of the conclusions or recommendations set forth in this report. ...

journal_title：Journal of the American Academy of Dermatology

authors： Miller OF 3rd,Phillips TJ

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Some patients develop a disproportionate number of cutaneous squamous cell carcinomas (SCCs) on their lower extremity (LE). OBJECTIVE:We sought to characterize the clinical features, treatment, and outcome in patients who develop multiple LE SCCs. METHODS:We identified 22 patients with 4 or more biopsy-dia...

journal_title：Journal of the American Academy of Dermatology

authors： Kim C,Ko CJ,Leffell DJ

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The Psoriasis Area and Severity Index (PASI) is considered the gold standard assessment tool for psoriasis severity, but PASI is limited by its complexity and insensitivity in people with mild psoriasis. OBJECTIVE:We sought to evaluate the product of a Physician Global Assessment (PGA) and Body Surface Area...

journal_title：Journal of the American Academy of Dermatology

authors： Walsh JA,McFadden M,Woodcock J,Clegg DO,Helliwell P,Dommasch E,Gelfand JM,Krueger GG,Duffin KC

更新日期：2013-12-01 00:00:00

abstract：:Five patients are described with the clinical and histopathologic picture, including flame figures, of eosinophilic cellulitis (Wells' syndrome). Two of them had documented tick bites in the center of these expanding annular lesions, and the histologic picture showed the diagnostic flame figures of Wells' syndrome (eo...

journal_title：Journal of the American Academy of Dermatology

authors： Schorr WF,Tauscheck AL,Dickson KB,Melski JW

更新日期：1984-12-01 00:00:00

abstract：:We report an unusual case of congenital melanocytic nevus presenting in a 19-year-old African woman as widespread papules and variably sized nodules and tumors affecting the entire body, including the palms, soles, and oral mucous membrane. Histopathologic examination of 3 representative skin lesions showed mainly der...

journal_title：Journal of the American Academy of Dermatology

authors： Rose C,Kaddu S,El-Sherif TF,Kerl H

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:Localized lymphedema is a nonneoplastic condition associated with obesity and predominantly involving the legs. This condition has distinctive clinical and histologic features and only rarely has been mentioned in the dermatologic literature. OBJECTIVE:We sought to evaluate the clinical and histopathologic ...

journal_title：Journal of the American Academy of Dermatology

authors： Plaza JA,Requena L,Kazakov DV,Vega E,Kacerovska D,Reyes G,Michal M,Suster S,Sangueza M

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Some patients with pemphigus vulgaris (PV) have mucous membrane erosions with minimal skin involvement (mucosal dominant type), and others show extensive skin blisters and erosions in addition to mucous membrane involvement (mucocutaneous type). Patients with pemphigus foliaceus (PF) show only skin involveme...

journal_title：Journal of the American Academy of Dermatology

authors： Amagai M,Tsunoda K,Zillikens D,Nagai T,Nishikawa T

更新日期：1999-02-01 00:00:00

abstract：:Three siblings with infantile-onset biotin-responsive multiple carboxylase deficiency are described. Recognition of the characteristic dermatologic manifestations, alopecia and periorificial dermatitis, should result in early diagnosis and institution of potentially lifesaving therapy with biotin. Other metabolic diso...

journal_title：Journal of the American Academy of Dermatology

authors： Williams ML,Packman S,Cowan MJ

更新日期：1983-07-01 00:00:00

abstract：:Atenolol is a beta-blocker commonly used for treating hypertension. It can induce various kinds of adverse side effects, including psoriasiform skin eruptions, skin necrosis, vasculitis, and (rarely) drug-induced connective tissue disease. We encountered a patient receiving atenolol for his hypertension for 3 years wh...

journal_title：Journal of the American Academy of Dermatology

authors： McGuiness M,Frye RA,Deng JS

更新日期：1997-08-01 00:00:00

abstract：:Mycobacterium avium complex, a common opportunistic pathogen among patients with AIDS, usually manifests as disseminated disease involving the lung, lymph nodes, and gastrointestinal tract. Primary cutaneous infections with M avium complex are extremely rare, and most cutaneous lesions are caused by dissemination. Cut...

journal_title：Journal of the American Academy of Dermatology

authors： Kayal JD,McCall CO

更新日期：2002-11-01 00:00:00

abstract：:Transepithelial elimination of granulomas was observed in histologic specimens taken from involved skin of a patient with disseminated tuberculosis and two patients with sarcoidosis. This phenomenon, previously also observed in other granulomatous disorders, represents one of the skin's several mechanisms to rid itsel...

journal_title：Journal of the American Academy of Dermatology

authors： Goette DK,Odom RB

更新日期：1986-01-01 00:00:00

abstract：:In recent years, our understanding of adipose tissue physiology and function has undergone an enormous transformation. Once considered a passive storage receptacle with a fixed number of cells and limited purpose, adipose tissue is now recognized as a complicated organ with important endocrine and metabolic functions....

journal_title：Journal of the American Academy of Dermatology

authors： Avram MM,Avram AS,James WD

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Onychomycosis, a fungal infection of the nail bed, is responsible for up to 50% of nail disorders. Although several surveys have been conducted in different parts of the world, there have been no multicenter epidemiologic surveys of onychomycosis in North America. OBJECTIVE:A 12-center study was undertaken ...

journal_title：Journal of the American Academy of Dermatology

authors： Ghannoum MA,Hajjeh RA,Scher R,Konnikov N,Gupta AK,Summerbell R,Sullivan S,Daniel R,Krusinski P,Fleckman P,Rich P,Odom R,Aly R,Pariser D,Zaiac M,Rebell G,Lesher J,Gerlach B,Ponce-De-Leon GF,Ghannoum A,Warner J,Is

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:Highly variable results of topical diphenylcyclopropenone (DPCP) in the treatment of alopecia areata have been reported so far. OBJECTIVE:The purposes of our study were to evaluate the efficacy and tolerability of DPCP in the treatment of chronic, extensive alopecia areata and to assess the long-term overal...

journal_title：Journal of the American Academy of Dermatology

authors： Cotellessa C,Peris K,Caracciolo E,Mordenti C,Chimenti S

更新日期：2001-01-01 00:00:00

abstract：:A patient with symptomatic urticaria pigmentosa who responded to nifedipine therapy is reported. Relief from cold-induced urtication and flushing was obtained with 10 mg taken orally three times daily. Calcium influx is an early step in the degranulation of mast cells. We hypothesize that the beneficial effect of nife...

journal_title：Journal of the American Academy of Dermatology

authors： Fairley JA,Pentland AP,Voorhees JJ

更新日期：1984-10-01 00:00:00

abstract：:Kyrle's disease is a chronic, genetically determined, hyperkeratotic disorder occurring in the middle forties. We report fourteen cases of this disorder in a population of 1.5 million over a period of 15 years. We observed a female/male ratio of 6:1. Straw-colored keratotic plugs and flat scale show a marked predispos...

journal_title：Journal of the American Academy of Dermatology

authors： Cunningham SR,Walsh M,Matthews R,Fulton R,Burrows D

更新日期：1987-01-01 00:00:00

abstract：:The term "the contact urticaria syndrome," proposed in 1975, has been generally accepted and led to proliferation of new examples. This paper summarizes this clinical material and presents a diagnostic and pathogenetic evaluation method. The risks (and minimization, thereof) of systemic skin test-induced reactions are...

journal_title：Journal of the American Academy of Dermatology

authors： von Krogh G,Maibach HI

更新日期：1981-09-01 00:00:00

abstract：:The evaluation of skin findings is critical in identifying many types of injury, whether self- inflicted or accidentally or intentionally inflicted. Specific causes of injury include homicide, abuse, neglect, assault, self-inflicted injury, suicide, torture, poisoning, and bioterrorism. Forensic findings in hair and n...

journal_title：Journal of the American Academy of Dermatology

authors： Reddy K,Lowenstein EJ

更新日期：2011-05-01 00:00:00

abstract：:Twenty percent of Americans will be over age 65 by 2030,1 and without a dedicated geriatrics curriculum in many residency trainings programs, dermatologists may be less familiar with age-associated side effects of common dermatologic medications. Herein, we provide a practical guide and clinical safety pearls for the ...

journal_title：Journal of the American Academy of Dermatology

authors： Grinnell M,Price KN,Shah A,Butler D

更新日期：2021-01-16 00:00:00

abstract：BACKGROUND:Primary closure of surgical defects after excision of cutaneous malignancies has been traditionally accomplished with layered closure. OBJECTIVE:We sought to compare the cosmetic outcome of cheek defects repaired with layered closure versus buried sutures and adhesive strips. METHODS:In all, 38 patients un...

journal_title：Journal of the American Academy of Dermatology

authors： Plotner AN,Mailler-Savage E,Adams B,Gloster HM Jr

更新日期：2011-06-01 00:00:00

abstract：:Cutaneous T-cell lymphoma is a malignancy of T cells that express a clone-specific heterodimer T-cell receptor for antigen. The second recognized case of an epidermotropic malignancy of T-cells expressing gamma/delta T-cell receptor-expressing cells is reported. The immunophenotype of the malignant T-cells was CD3+, C...

journal_title：Journal of the American Academy of Dermatology

authors： Heald P,Buckley P,Gilliam A,Perez M,Knobler R,Kacinski B,Edelson R

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND:The pathologic evaluation of mycosis fungoides (MF) is a challenging area in dermatopathology. OBJECTIVE:We sought to determine the usefulness of flow cytometry for the diagnosis of MF from skin biopsy specimens. METHODS:Skin biopsy specimens from 22 patients with a clinical suggestion for MF were evaluate...

journal_title：Journal of the American Academy of Dermatology

authors： Oshtory S,Apisarnthanarax N,Gilliam AC,Cooper KD,Meyerson HJ

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Tissue-destructive and more selective cytotoxic therapies are the main methods used to treat actinic cheilitis. A topical immune stimulant, 5% imiquimod cream, has recently been used for treatment of cutaneous epithelial malignancies including squamous cell carcinoma in situ and basal cell carcinoma. OBJECT...

journal_title：Journal of the American Academy of Dermatology

authors： Smith KJ,Germain M,Yeager J,Skelton H

更新日期：2002-10-01 00:00:00